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Spring 2013 Course Announcement Plant Biochemistry (Biochemistry/Botany 621) Plants harnness sunlight energy, fix atomospheric carbon dioxide, and produce a diverse array of chemical compounds to survive in challenging ecological niches. Plant-derived metabolites are also major sources of human food, fiber, fuel, and medicine. The Biochemistry/Botany 621 course covers topics related to plant metabolism and discusses how plants generate carbon and energy sources by photosynthesis and synthesize various compounds through complex networks of metabolic pathways. Various analytical tools (e.g., mass spectrometry, NMR) that are used in plant biochemistry research will be also introduced. The course is designed for graduate students and advanced undergraduates and has two 75-minute classes per week, which consist of lectures and student presentations based on primary scientific literature. General chemistry and biochemistry are prerequisites to this course. Time and location: Tuesdays and Thursdays from 9:30-10:45 am in Biochemistry building room 1116. Textbook: There is no textbook for this course but we recommend two excellent plant biochemistry books. • Biochemistry and Molecular Biology of Plants. Buchannan, BB, Gruissem, W, and Jones, RL editors. American Society of Plant Physiologists publisher (2000) (www.aspb.org) • Plant Biochemistry and Molecular Biology. Heldt, H-W. Oxford University Press, 3rd ed. (2005) Instructors: Sebastian Y. Bednarek, Biochemistry, [email protected] Hiroshi A. Maeda, Botany, [email protected] John Ralph, Biochemistry, [email protected] Guest lecturers: Timothy J. Donohue, Bacteriology, [email protected] Michael R. Sussman, Biochemistry, [email protected] Jean-Michel Ané, Agronomy, [email protected] Tentative topics: 0) Introduction (overview of plant metabolism) 1) Photosynthesis light-dependent reaction 2) Photosynthesis light-independent reaction 3) Central carbon metabolism (sucrose/starch biosynthesis, photosynthate translocation) 4) Cellular respiration 5) Genomics and proteomics (tour to UW Biotech Center) 6) Metabolomics 7) Nitrogen metabolism / Rhizobia-plant symbiosis 8) Amino acid biosynthesis (GC-MS) 9) Specialized metabolism I (terpenoids) 10) Specialized metabolism II (phenylpropanoids, LC-MS) 11) Lipid metabolism I (fatty acid biosynthesis) 12) Lipid metabolism II (glycolipids, plant cuticles) 13) Plant cell wall I (sugar metabolism) 14) Plant cell wall II (polysaccharides) 15) Plant cell wall III (lignin, NMR) Please contact Hiroshi Maeda <[email protected]>, if you would like further information.