Metabolic downregulation during diapause in embryos of Artemia
... Trehalose has been shown to accumulate in desiccation tolerant tissues of plant and animal species (Clegg 2001). Trehalose is able to stabilize proteins and membranes during freezing and drying (Crowe et al. 2005). Numerous in vitro studies have demonstrated the ability of molecules like trehalose ...
... Trehalose has been shown to accumulate in desiccation tolerant tissues of plant and animal species (Clegg 2001). Trehalose is able to stabilize proteins and membranes during freezing and drying (Crowe et al. 2005). Numerous in vitro studies have demonstrated the ability of molecules like trehalose ...
Riboflavin (Vitamin B )
... Riboflavin is known as vitamin B2, riboflavin was the second B complex vitamin to be discovered. Riboflavin is the precursor for the coenzymes, flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD). The enzymes that require FMN or FAD as cofactors are termed flavoproteins. Several flavop ...
... Riboflavin is known as vitamin B2, riboflavin was the second B complex vitamin to be discovered. Riboflavin is the precursor for the coenzymes, flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD). The enzymes that require FMN or FAD as cofactors are termed flavoproteins. Several flavop ...
Evidence of separate pathways for lactate uptake and release by the
... from decreased blood flow in subendocardium (49) or inter- or intracellular compartmentation of lactate metabolism. Arguing against tissue heterogeneity is an in vivo study in newborn lambs (2), in which simultaneous myocardial lactate uptake and release were observed despite reports that, in the la ...
... from decreased blood flow in subendocardium (49) or inter- or intracellular compartmentation of lactate metabolism. Arguing against tissue heterogeneity is an in vivo study in newborn lambs (2), in which simultaneous myocardial lactate uptake and release were observed despite reports that, in the la ...
CYP 2D6 Polymorphism
... „Every human differs (more or less) “ The phenotype can be distinguished by the actual activity or the amount of the expressed CYP enzyme. The genotype, however, is determined by the individual DNA sequence. Human: two sets of chromosomes That mean: The same genotype enables different phenotypes Dep ...
... „Every human differs (more or less) “ The phenotype can be distinguished by the actual activity or the amount of the expressed CYP enzyme. The genotype, however, is determined by the individual DNA sequence. Human: two sets of chromosomes That mean: The same genotype enables different phenotypes Dep ...
Cytochrome P450 and Polymorphism - uni
... „Every human differs (more or less) “ The phenotype can be distinguished by the actual activity or the amount of the expressed CYP enzyme. The genotype, however, is determined by the individual DNA sequence. Human: two sets of chromosomes ...
... „Every human differs (more or less) “ The phenotype can be distinguished by the actual activity or the amount of the expressed CYP enzyme. The genotype, however, is determined by the individual DNA sequence. Human: two sets of chromosomes ...
The metabolic responses of high intensity intermittent exercise in
... effect of interspersed work and passive rest. Although the aforementioned studies were training studies, this study used single bouts of workload matched HIIE and moderate intensity, continuous exercise (CON) and found similar levels of fat utilisation between the two trials as well as significantly ...
... effect of interspersed work and passive rest. Although the aforementioned studies were training studies, this study used single bouts of workload matched HIIE and moderate intensity, continuous exercise (CON) and found similar levels of fat utilisation between the two trials as well as significantly ...
Elucidating Flux Regulation of the Fermentation Modes of
... Christian has taught me numerous principles, skills and knowledge in practical as well as theoretical molecular biology and cellular metabolism. From the very first day he has helped me, a person without any previous experience in biological experiments, to survive in the lab. He always came up with ...
... Christian has taught me numerous principles, skills and knowledge in practical as well as theoretical molecular biology and cellular metabolism. From the very first day he has helped me, a person without any previous experience in biological experiments, to survive in the lab. He always came up with ...
Midazolam Oxidation by Cytochrome P450 3A4 and Active
... were generated with the megaprimer method. In the first amplification reaction, the mutagenic primer (see Fig. 1) and a pSE380 3⬘specific primer were used with pSE3A4His as the template (Domanski et al., 1998). The product was used in a second amplification as a primer in conjunction with a pSE380 5 ...
... were generated with the megaprimer method. In the first amplification reaction, the mutagenic primer (see Fig. 1) and a pSE380 3⬘specific primer were used with pSE3A4His as the template (Domanski et al., 1998). The product was used in a second amplification as a primer in conjunction with a pSE380 5 ...
- The University of Liverpool Repository
... These reactions show a clear dose-dependent relationship and can be avoided by lowering the dose. These reactions are rarely life threatening, and account for 80% of all drug reactions (Williams 2006). Off-target (idiosyncratic) reactions are not related to the primary or secondary pharmacology of t ...
... These reactions show a clear dose-dependent relationship and can be avoided by lowering the dose. These reactions are rarely life threatening, and account for 80% of all drug reactions (Williams 2006). Off-target (idiosyncratic) reactions are not related to the primary or secondary pharmacology of t ...
Mechanism of Posttranslational Regulation of Phenol
... been separated and purified from rat liver (11, 12). PST has been cloned and expressed in Escherichia coli (13). During the growth of the bacterial cells, the R- and β-forms of the sulfotransferase are produced and are both active. The ratio of the two forms PST expresses is dependent on cell cultur ...
... been separated and purified from rat liver (11, 12). PST has been cloned and expressed in Escherichia coli (13). During the growth of the bacterial cells, the R- and β-forms of the sulfotransferase are produced and are both active. The ratio of the two forms PST expresses is dependent on cell cultur ...
Sucrose breakdown in the potato tuber - publish.UP
... Then I would like to thank Prof. Thomas Altmann and Prof. David Fell (Oxford) for agreeing to examine this thesis. ...
... Then I would like to thank Prof. Thomas Altmann and Prof. David Fell (Oxford) for agreeing to examine this thesis. ...
Mutational and spectroscopic studies of the significance of the active
... interesting that Gln at position 146 does not enforce Mn-binding. Cambialistic 4 SOD from Porphyromonas gingivalis has also been mutated to incorporate the Gln characteristic of MnSOD, instead of its native Gln characteristic of FeSOD [18]. This resulted in lower-than-WT activity with Fe bound but h ...
... interesting that Gln at position 146 does not enforce Mn-binding. Cambialistic 4 SOD from Porphyromonas gingivalis has also been mutated to incorporate the Gln characteristic of MnSOD, instead of its native Gln characteristic of FeSOD [18]. This resulted in lower-than-WT activity with Fe bound but h ...
Regulation of Urea Synthesis by Agmatine in the Perfused Liver
... Samples were dried under N2 and azeotroped with methylene chloride. Then 100 µl of methanolic HCl (3N) (Supelco) was added. Capped vials were heated at 60oC for 10 min., cooled and dried under a gentle stream of N2. The residue was extracted into 1 ml of ethyl acetate and 300 µl of H2O after vortexi ...
... Samples were dried under N2 and azeotroped with methylene chloride. Then 100 µl of methanolic HCl (3N) (Supelco) was added. Capped vials were heated at 60oC for 10 min., cooled and dried under a gentle stream of N2. The residue was extracted into 1 ml of ethyl acetate and 300 µl of H2O after vortexi ...
- Surrey Research Insight Open Access
... toxins (over 20 exotoxins in certain strains) which are responsible for illness in humans. The most clinically significant of C. perfringens toxins, α-toxin, is the most common cause of gas gangrene; a life-threatening disease characterised by fever, edema, myonecrosis, pain and gas production (Saku ...
... toxins (over 20 exotoxins in certain strains) which are responsible for illness in humans. The most clinically significant of C. perfringens toxins, α-toxin, is the most common cause of gas gangrene; a life-threatening disease characterised by fever, edema, myonecrosis, pain and gas production (Saku ...
Roles of the Methylcitrate and Methylmalonyl
... To detect propionate-derived intermediates, metabolite analysis by targeted liquid chromatography-tandem mass spectrometry (LC-MS/MS) was used in this study. Accumulation of these metabolites under propionate exposure was identified in a strain of M. smegmatis impaired in both metabolic routes, but ...
... To detect propionate-derived intermediates, metabolite analysis by targeted liquid chromatography-tandem mass spectrometry (LC-MS/MS) was used in this study. Accumulation of these metabolites under propionate exposure was identified in a strain of M. smegmatis impaired in both metabolic routes, but ...
coordination of some monodentate and hybrid multident ate
... feature of this work, the metal-phosphine complexes. It describes common routes for the preparation of transition-metal phosphine complexes, some of which are implicated in this work, followed by an analysis of the metal-phosphine bonding and the different factors contributing to its stability. In a ...
... feature of this work, the metal-phosphine complexes. It describes common routes for the preparation of transition-metal phosphine complexes, some of which are implicated in this work, followed by an analysis of the metal-phosphine bonding and the different factors contributing to its stability. In a ...
Modern Analytical Chemistry
... An additional problem is encountered when the isolated solid is nonstoichiometric. For example, precipitating Mn2+ as Mn(OH)2, followed by heating to produce the oxide, frequently produces a solid with a stoichiometry of MnOx , where x varies between 1 and 2. In this case the nonstoichiometric produ ...
... An additional problem is encountered when the isolated solid is nonstoichiometric. For example, precipitating Mn2+ as Mn(OH)2, followed by heating to produce the oxide, frequently produces a solid with a stoichiometry of MnOx , where x varies between 1 and 2. In this case the nonstoichiometric produ ...
Physiological Strategies During Animal Diapause: Lessons from
... embryos are introduced into the brood pouch and then released into the lake. These embryos enter diapause at the gastrula stage (Clegg and Conte, 1980). Although the developmental cessation is complete by the time embryos are released by the female into the water column, the metabolic depression req ...
... embryos are introduced into the brood pouch and then released into the lake. These embryos enter diapause at the gastrula stage (Clegg and Conte, 1980). Although the developmental cessation is complete by the time embryos are released by the female into the water column, the metabolic depression req ...
Carnitine Overview
... Long-chain fatty acids (>12 C) are extracted from triglycerides by an intracellular lipase. Fatty acids are then activated by Acyl-CoA Synthetase, located in the outer mitochondrial membrane. ...
... Long-chain fatty acids (>12 C) are extracted from triglycerides by an intracellular lipase. Fatty acids are then activated by Acyl-CoA Synthetase, located in the outer mitochondrial membrane. ...
Copyright 2010 Scott R
... water, and the structure of the partial hydrolysis product [La(H3BNMe2BH3)2(OH)]4 is described. Field ionization MS data, melting and decomposition points, thermogravimetric data, and NMR data, including an analysis of the paramagnetic lanthanide induced shifts (LIS), are reported for all of the co ...
... water, and the structure of the partial hydrolysis product [La(H3BNMe2BH3)2(OH)]4 is described. Field ionization MS data, melting and decomposition points, thermogravimetric data, and NMR data, including an analysis of the paramagnetic lanthanide induced shifts (LIS), are reported for all of the co ...
Capability of Lactobacillus reuteri to Produce an Active Form of
... which fermentation was divided into two stages. In the first, 24 h of fermentation, the bacteria were grown anaerobically at 37°C in anaerobic incubator and after that, the cultivation was shifted to the aerobic cultivation with a rotary shaker at 120 rpm for 8 h, (B) Addition of DMB (100 mg/L) with ...
... which fermentation was divided into two stages. In the first, 24 h of fermentation, the bacteria were grown anaerobically at 37°C in anaerobic incubator and after that, the cultivation was shifted to the aerobic cultivation with a rotary shaker at 120 rpm for 8 h, (B) Addition of DMB (100 mg/L) with ...
Derivatization - Sigma
... environmental disciplines. Derivatization enables the analyst to analyze a wide variety of compounds by GC, GC-MS, HPLC and LC-MS that were otherwise less volatile and unstable for these techniques. In general, analytical derivatization is employed for two reasons: ...
... environmental disciplines. Derivatization enables the analyst to analyze a wide variety of compounds by GC, GC-MS, HPLC and LC-MS that were otherwise less volatile and unstable for these techniques. In general, analytical derivatization is employed for two reasons: ...
Selective 15N labeling and direct observation by NMR
... chains of Asn and Gln (50 000 scans), obtained using a 1.0 s relaxation delay, and (c) 2 mM Fe-SOD labeled exclusively in the side chains of Gln (20 000 scans) obtained using a 3 s relaxation delay. (d) Non-decoupled 15N spectrum of a different preparation of Fe-SOD, labeled exclusively in the side ...
... chains of Asn and Gln (50 000 scans), obtained using a 1.0 s relaxation delay, and (c) 2 mM Fe-SOD labeled exclusively in the side chains of Gln (20 000 scans) obtained using a 3 s relaxation delay. (d) Non-decoupled 15N spectrum of a different preparation of Fe-SOD, labeled exclusively in the side ...
Malic acid production by Aspergillus oryzae
... concerning yields, rates and titers. This strain can then be used in a biorefinery, which is in analogy to the petroleum refinery producing fuels, power and chemicals, just that the ...
... concerning yields, rates and titers. This strain can then be used in a biorefinery, which is in analogy to the petroleum refinery producing fuels, power and chemicals, just that the ...
The Reciprocal Principle of Selectand-Selector-Systems in
... 1. Introduction Separation approaches in highly selective supramolecular chromatography [1,2], with their most refined expression of stereochemical resolution [3], rely on the fast and reversible non-covalent association equilibrium between functionally and/or structurally complementary partners. Th ...
... 1. Introduction Separation approaches in highly selective supramolecular chromatography [1,2], with their most refined expression of stereochemical resolution [3], rely on the fast and reversible non-covalent association equilibrium between functionally and/or structurally complementary partners. Th ...