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Chapter 23 Digestive System Elsevier items and derived items © 2007, 2003, 2000 by Saunders, an imprint of Elsevier Inc. Slide 1 Overview of the Digestive System • Functions of the Digestive System – – – – Ingestion (eating) Digestion Absorption Elimination • The Wall of the Digestive Tract and Membranes – Four layers: mucosal, submucosa, muscle, serosa – Peritoneal membranes: mesentery, mesocolon, greater and lesser omentum Slide 2 Structures and Organs of the Digestive System • Mouth – Teeth and tongue – Salivary glands: parotid, submandibular, and sublingual • Pharynx (Throat) Slide 3 Structures and Organs of the Digestive System - cont’d • Esophagus – The esophagus is a long tube that connects the pharynx to the stomach. – There are two sphincters. • Stomach – The three parts of the stomach are the fundus, body, and pylorus. – The stomach functions in digestion; its most important role is regulate the rate at which chyme is delivered to the small intestine. Slide 4 Structures and Organs of the Digestive System - cont’d • Small Intestine – The three parts of the small intestine are the duodenum, jejunum, and ileum. – Most of the digestion and absorption occurs within the duodenum. – The end-products of digestion are absorbed into villi. Slide 5 Structures and Organs of the Digestive System - cont’d • Large Intestine – The large intestine consists of the cecum, ascending colon, transverse colon, descending colon, sigmoid colon, rectum, and anus. – The large intestine functions in absorption of water and electrolytes. Slide 6 Accessory Digestive Organs • Liver – The liver has many functions; its most important digestive function is the secretion of bile. – The liver receives blood from the portal vein; portal blood is rich in digestive end products. Slide 7 Accessory Digestive Organs - cont’d • Biliary Tree – The biliary tree is composed of the bile ducts that connect the liver, gallbladder, and duodenum. – The common bile duct empties into the duodenum. Slide 8 Accessory Digestive Organs - cont’d • Gallbladder – The gallbladder functions to store and concentrate bile. – The gallbladder contracts and releases bile in response to the hormone cholecystokinin (CCK). Slide 9 Accessory Digestive Organs - cont’d • Pancreas – The pancreas secretes the most important digestive enzymes. – The pancreatic enzymes empty into the duodenum. Slide 10 Digestion and Absorption • Carbohydrate Digestion – To be absorbed, carbohydrates must be broken down into glucose. – Carbohydrates are digested by enzymes called amylases and disaccharidases. Slide 11 Digestion and Absorption - cont’d • Protein Digestion – To be absorbed, proteins must be broken down into amino acids. – Proteins are broken down by proteolytic enzymes or proteases. Slide 12 Digestion and Absorption - cont’d • Fat Digestion – To be absorbed, fats must be broken down into fatty acids and glycerol. – Fats are digested by enzymes called lipases. Fats are first emulsified by bile. Slide 13 Nutrition and Body Energy • Carbohydrates – Carbohydrates are either simple or complex. – Glucose, the simplest carbohydrate, is the major fuel used by the body for energy. Slide 14 Nutrition and Body Energy - cont’d • Protein – The body needs essential amino acids, which it cannot synthesize, and nonessential amino acids, which it can synthesize. – Dietary proteins are complete or incomplete. Slide 15 Nutrition and Body Energy - cont’d • Fats (Lipids) – Most dietary lipids are triglycerides. – Fats are either saturated fats (like butter) or unsaturated fats (like oils). Slide 16 Nutrition and Body Energy - cont’d • Vitamins – Vitamins are small organic molecules that help regulate cell metabolism. Dietary vitamin deficiencies give rise to many diseases (see Table 23-2). – Vitamins are either water soluble (vitamins B and C) or fat soluble (vitamins A, D, E, and K). Slide 17 Nutrition and Body Energy - cont’d • Minerals – Minerals are inorganic substances necessary for normal body function. – Mineral deficiencies can cause serious health problems. Slide 18 Nutrition and Body Energy - cont’d • Body Energy – The body needs energy to do its work and maintain body temperature. – The basal metabolic rate (BMR) is the amount of energy the body requires per unit time to perform essential activities at rest. – Metabolism is determined by many factors, including age; gender; surface area; emotional state; overall health status; and hormones (especially thyroxine). Slide 19