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Transcript
Digestive System
Anatomy and Physiology
BIO 169
Turk
Digestive System

Alimentary canal
–


gastrointestinal (GI) tract
mouth, pharynx, esophagus,
stomach, small intestine,
and large intestine
accessory digestive organs
include
–
teeth, tongue, gallbladder,
salivary glands, liver, and
pancreas
Digestive Processes


Ingestion
Propulsion
–

Mechanical digestion
–



swallowing is followed by
peristalsis
chewing, mixing food with saliva,
churning, and segmentation
Chemical digestion
Absorption
Defecation
Digestive Processes
chemoreceptors and mechanoreceptors
 parasympathetic enhances secretory activities
and mobility
 sympathetic inhibits
digestive activity

Digestive System Organs


visceral peritoneum
parietal peritoneum
–
–

peritoneal cavity
Mesentery
all digestive organs have four tunics
–
Mucosa



secretes mucus, digestive enzymes, and hormones
absorbs end products of digestion
protects against pathogens
Digestive System Organs
–
Submucosa

–
Muscularis Externa (aka muscularis)

–
connective tissue with blood vessels, lymph vessels,
lymph nodes, and nerve fibers
responsible for segmentation and peristalsis
Serosa


visceral peritoneum
adventitia
Digestive System Organs

Mouth and Associated Organs
–
–
–
oral cavity or buccal cavity
lined with stratified squmaous epithelium
Palate

–
hard anterior and soft posterior
Tongue



lingual frenulum
Filiform, fungiform, circumvallate
sulcus terminalis
Digestive System Organs

Mouth and Associated Organs
cont.
–
salivary glands





bolus
parotid, submandibular, sublingual
serous cells
mucous cells
Amylase, mucin, lysozyme, and IgA
Digestive System Organs

Mouth and Associated Organs cont.
–
–
–
–
–
–
–
–
Teeth
Mastication
deciduous teeth (baby teeth or milk teeth)
Incisors, canines, bicuspids (premolars), and molars
Crown is enamel covered
dentin
pulp
Gingivitis and periodontitis
Digestive System Organs

Pharynx
–
–
–

oropharynx than laryngopharynx
inner longitudinal muscles
outer pharyngeal constrictor muscles
Esophagus
–
–
cardiac (gastroesophageal) sphincter
Heartburn - hiatus hernia
Digestive System Organs

Esophagus cont.
–
Swallowing






buccal phase
involuntary pharyngeal-esophageal phase
tongue blocks reentry into the mouth
soft palate closes off the nasopharynx
larynx rises so the epiglottis covers the respiratory
passages
peristalsis
Digestive System Organs

Stomach
–
–
–
–
where protein digestion begins
chyme (a creamy paste)
rugae (folds)
pyloric region is inferior and funnel shaped
Digestive System Organs

Stomach cont.
–
–
gastric pits lead to gastric glands that produce
gastric juices
parietal (oxyntic) cells

–
secrete hydrochloric acid and intrinsic factor
chief (zymogenic) cells

produce pepsinogen (inactive form of pepsin)
Digestive System Organs

Stomach cont.
–
–
mucosal barrier of bicarbonate-rich mucus
gastric ulcers



–
pepsin is the enzyme involved in protein digestion

–
hypersecretion of hydrochloric acid
hyposecretion of mucus
Helicobacter pylori
children also have rennin
alcohol and aspirin
Digestive System Organs

Stomach cont.
–
–
Gastrin
cephalic (reflex) phase

–
–
–
triggered by sight, smell, taste, or
thought of food
gastric phase
intestinal phase
emetic center of the medulla
Digestive System Organs

Small Intestine and Associated Structures
–
–
pyloric sphincter to ileocecal valve
duodenum curves around the head of the pancreas

–
–
hepatopancreatic ampulla
Jejunum
ileum
Digestive System Organs

Small Intestine and Associated Structures cont.
–
–
plicae circulares (circular folds)
Villi



–
simple columnar absorptive cells

–
Lacteal
Microvilli
brush border enzymes
goblet cells and enteroendocrine cells
duodenal glands secrete an alkaline mucus to
neutralize the stomach acid entering
Digestive System Organs

Liver
–
Bile in the common hepatic duct goes to the
duodenum

–
–
–
fuses with the cystic duct that drains the gallbladder to
make the bile duct
liver sinusoids are very leaky capillaries
Kupffer cell (hepatic macrophages)
process nutrients – store fat soluble vitamins – help
with detoxification of the blood
Digestive System Organs

Liver
–
Hepatitis


–
–
–
–
HVB, HVC, HVD
HVA
Cirrhosis
bile contains bile salts, bile pigment, cholesterol,
natural fats, phospholipids, and electrolytes
bile salts emulsify fats to facilitate fat and
cholesterol absorption
bilirubin
Digestive System Organs

Gallbladder
–
–
–
stores bile not immediately needed and
concentrates it
cholecystokinin (CCK)
gallstones
Digestive System Organs

Pancreas
–
–
–
–
main pancreatic duct fuses with the bile duct
acini – clusters of secretory cells surrounding ducts
pancreatic islets (islets of Langerhans) which
release insulin and glucagon
pancreatic juice is alkaline
Digestive System Organs

Large Intestine
–
–
–
–
–
ileocecal valve to the anus
absorb water from food residue and eliminate it as
feces
teniae coli
Haustra
Cecum with veriform appendix
Digestive System Organs

Large Intestine
–
–
–
–
–
–
–
–
Ascending colon
transerse colon
descending colon
sigmoid colon
Rectum
anal canal to the anus
involuntary internal anal sphincter
voluntary external anal sphincter
Digestive System Organs

Large Intestine
–
–
simple columnar epithelium
stratified squamous epithelium

–
–
anal sinuses
haustral contraction
mass movements


gastrocolic reflex
defecation reflex
Digestion


Hydrolysis
Carbohydrates – monosaccharides
–
–

Proteins - amino acids
–

pepsin – works best in acidic conditions
Lipids (fats)
–

digestion begins in the mouth (salivary amylase)
pancreatic amylase in the small intestine
lipases are relased by the pancrease
Nucleic Acids - nucleotides
Absorption



active transport
absorption of iron and calcium occur in the
duodenum
95% of water is absorbed by the small intestine
by osmosis