* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Download EvolutionNotesTE
Dual inheritance theory wikipedia , lookup
X-inactivation wikipedia , lookup
Human genetic variation wikipedia , lookup
SNP genotyping wikipedia , lookup
Inbreeding avoidance wikipedia , lookup
Pharmacogenomics wikipedia , lookup
History of genetic engineering wikipedia , lookup
Quantitative trait locus wikipedia , lookup
Polymorphism (biology) wikipedia , lookup
Genome-wide association study wikipedia , lookup
Koinophilia wikipedia , lookup
Population genetics wikipedia , lookup
Genetic drift wikipedia , lookup
Microevolution wikipedia , lookup
Evolution: Change over time; the process by which modern organisms have descended from ancient organisms ∆ 𝒄𝒉𝒂𝒏𝒈𝒆 = 𝒕𝒊𝒎𝒆 𝒕 Tiktaalik: Transitional fossil DNA: Take a minute and write down everything you know about DNA End Chromosomes: Take a minute and write down everything you know about Chromosomes End Inheritance: Take a minute and write down everything you know about how traits are inherited End Genes & Alleles Take a minute and write down everything you know about genes and alleles End Phenotype and Genotype Take a minute and write down everything you know about phenotype and genotype End Phylogeny And the evolution of plants Phylogeny • Evolutionary history of a species What is a plant? All Land Plants (Embryophytes): • Alternation of Generations • Roots & Shoots • Cuticle (prevents water loss) Bryophytes: Mosses, Liverworts and Hornwarts • What makes them special? – No vascular tissue • Can’t transport nutrients -> limited size – Need water to reproduce – No seeds Nonvascular Plants Time Mosses, liverworts, hornworts (vascular tissue) Ancestral Algae (Autotroph) Vascular Plants Ferns: Seedless Vascular Plants • What makes them special? • No seeds • Need water to reproduce Time Mosses, liverworts, hornworts Seeded Vascular Plants Ferns (Seeds) (vascular tissue) Ancestral Algae (Autotroph) Gymnosperm (conifers, gingkoes, cycads) • What makes them special? • Wind pollination, Seeds, • No flowers Mosses, liverworts, hornworts Ferns Gymnosperm Angiosperm Time Flowers, (Seeds) (vascular tissue) Ancestral Algae (Autotroph) Angiosperm (Flowering Plants) • What makes them special? • Flowers- pollination by animals • Double fertilization – Seed doesn't develop w/out pollination Modeling Phylogenetic Trees Ferns Gymnosperm Time Mosses, liverworts, hornworts Angiosperm Look at the Nodes Ancestral Algae Any of the branches can be rotated at the nodes: Mosses, Ferns Angiosperm Time liverworts, hornworts Gymnosperm Look at the Nodes Ancestral Algae Are Angiosperm more closely related to Ferns, or to mosses/liverworts and hornworts? Gymnosperm Time Ferns Ferns Angiosperm Mosses, liverworts, hornworts Are Ferns more closely related to Angiosperm, or to Gymosperm? Angiosperm Ferns Time Gymnosperm Mosses, liverworts, hornworts Neither: They are equally related Tree of Life Tree of Life Bonus Opportunity • Fantasy Phylogeny – Create a phylogenetic tree of fantasy creatures – Include at least 5 creatures – Include descriptions of creatures – Describe characteristic that is associated with each node (example: seeds, vascular tissue in plants) Lizard Lab • 3 Parts- must be done sequentially. When you complete part 1, return that handout and pickup the next. • Turn in at end of class- we will be working on them next class also. They are due on _____ Evolution: A more technical definition frequency in • the change in allele __________ a population, over _________. time Mechanisms of Evolution • Mutation Change in the DNA code “Instant Evolution” Almost always harmful. Why? Mechanisms of Evolution • Migration Movement of organisms in or out of a population Changes allele frequency Mechanisms of Evolution Drift • Genetic _________which is a sampling ______ error. Founder Effect – ____________in which a population is isolated from the parent population. • This new population is a random sample of the original, containing different Allele frequencies ______________ Mechanisms of Evolution Drift • Genetic _________which is a sampling ______ error. Bottleneck Effect – ___________ in which a population declines rapidly, so that only a small number of members remains. The remaining members are essentially frequencies a random sample and have different Allele ______, _________ than the parent population. Cheetahs underwent this. The population – ______ 99 shares ____% of their DNA- they are siblings more closely related than most _____. Mechanisms of Evolution • ______ Natural _______ Selection was proposed by ______ _____ in The Origin of Species. Charles Darwin Conditions: – There must be variation _______ heritable variation – The ________must be ________ survive – More are born ____ than will _________. variations survive better than – Some ________ others. Mechanisms of Evolution • ______ Natural _______ Selection increases fitness __________, which is measured in the number of offspring an individual has, relative to other members of its species.. Definitions: Genotype vs Phenotype • Genotype: What your genes are; 2 alleles • Phenotype: What you look like; your appearance Genotype or Phenotype? • The bunny has brown fur… Phenotype Genotype or Phenotype? • Lucy is a carrier for X-linked color blindness. Genotype Genotype or Phenotype? • The flowers are pink. Phenotype Genotype or Phenotype? • The plants are short Phenotype Definitions: Dominant & Recessive • Dominant: Represented by a capital letter Single copy determines the trait “overrides” other alleles • Recessive: Represented by a lower-case letter Can be “masked” Dominant or Recessive • The “O” in blood types Recessive – It may be helpful to know that an individual with an AO genotype has type A, and an individual with BO has type B, while an individual with OO has blood type O Dominant or Recessive Dominant • If an individual inherits even a single copy of the allele associated with Huntington’s disease, the individual will develop the disease. Dominant or Recessive Recessive • Brown-eyed parents sometimes have blue-eyed children. Is the blue eyed allele dominant, or recessive? Definitions: Homozygous & Heterozygous • Homozygous: Homo- prefix meaning same Refers to an organism with 2 identical copies of an allele. Example: AA or aa • Heterozygous Hetero- prefix meaning different Refers to an organism with 2 different alleles Example: Aa A) homozygous dominant… B) homozygous recessive… C) heterozygous…? • AA Homozygous dominant A) homozygous dominant… B) homozygous recessive… C) heterozygous…? • Aa Heterozygous A) homozygous dominant… B) homozygous recessive… C) heterozygous…? • An individual is a carrier for sickle cell disease Heterozygous A) homozygous dominant… B) homozygous recessive… C) heterozygous…? • Pure breeding purple flowers, given that crossing purple and white flowers will result in purple flowers. Homozygous dominant A) homozygous dominant… B) homozygous recessive… C) heterozygous…? • An individual with O blood type. Homozygous recessive Write the genotype: • Homozygous dominant – (use ‘A’ and ‘a’ to represent the alleles) AA Write the genotype: • An individual that will not develop Huntington's disease. aa Write the genotype: • An individual with blue eyes. Use ’B’ and ‘b’ to represent the alleles bb Write the genotype: • Mary has type A, blood type, but her father had type O. AO Hardy-Weinberg Principle allele • Principle stating that _______ change unless frequencies do not _____ there is a factor causing change Hardy-Weinberg Principle Assumes: – – – – – Large population No Migration Random Mating No Mutations No Selection Hardy-Weinberg Principle • Equations: 𝑝 + 𝑞 = 1 – Where 𝑝 is: frequency of the dominant allele – Where 𝑞 is: frequency of the recessive allele Hardy-Weinberg Principle • Equations: 𝑝2 + 2𝑝𝑞 + 𝑞 2 = 1 • Where 𝑝2 is: frequency of homozygous • dominant genotype in population Where 𝑞 2 is: frequency of homozygous recessive genotype in population • Where 2𝑝𝑞 is: frequency of heterozygous genotype in population Hardy-Weinberg Principle • Video on how to solve HardyWeinberg problems • If the frequency of the dominant allele is .3 – What is the frequency of the recessive allele? Given: 𝑝 = .3 Equation: 𝑝+𝑞 =1 𝑞 =1−𝑝 𝑞 = 1 − .3 𝑞 = .7 • If the frequency of the dominant allele is .3 𝑝 = .3 𝑞 = .7 – What percentage of the population will be heterozygous for the trait? Equation: 𝑝2 + 2𝑝𝑞 + 𝑞2 = 1 Calculate 2pq 2𝑝𝑞 = 2 ∙ .3 ∙ (.7) 2𝑝𝑞 = .42 So, 42% Solve: The frequency of the homozygous recessive genotype is 0.09. What is the frequency of individuals that are homozygous for the dominant allele? Given: Find: 𝑞 = .09 𝑝2 = 𝑝+𝑞 =1 𝑝=1−𝑞 𝑝 = 1 − .09 𝑝 = .91 (.91)2 =.83 Solve: The frequency of the homozygous recessive genotype is 0.09. In a population of 1000, how many would have the dominant phenotype ? Given: 𝑞 = .09 𝑝 = .91 Find: 1000 ∗ (2𝑝𝑞 + 𝑝2 ) = 1000 ∗ (2 (.09)(.91) + (.91)2 ) = 9938 Solve: If the frequency of two alleles in a gene pool is 90% A and 10% a, what is the frequency of individuals in the population with the genotype Aa? Find: Given: 𝑝 = .9 𝑞 = .1 2𝑝𝑞 = 2 .9 . 1) = .18 Solve: In humans, Rh-positive individuals have the Rh antigen on their red blood cells, while Rh-negative individuals do not. If the Rh-positive phenotype is produced by a dominant gene (A), and the Rhnegative phenotype is due to its recessive allele (a), what is the frequency of the Rh-positive allele if 84% of a population is Rh-positive? Given: Find: 2𝑝𝑞 + 𝑝2 = .84 𝑝2 + 2𝑝𝑞 + 𝑞2 = 1 𝑞2 = 1-(𝑝2 + 2𝑝𝑞) 𝑞2 = 1-.84 𝑞2 = .16 𝑞2 = .16 𝑞 = .4 𝑝= 𝑝= 𝑝+𝑞 =1 Linking HW to Genetic Drift • Bozeman Bio: https://youtu.be/mjQ_yN5znyk?t= 63 Problem 1- first set of Hardy-Weinberg Problems