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Subject 12 - Chronic heart failure (4 hours) Place Training Room, cardiology department . Purpose To know: • The main causes of heart failure • Pathogenesis of disorders of the central and peripheral hemodynamics in various forms ( leftand right heart ). Systolic and diastolic dysfunction. The role of the kidneys and endocrine factors. • Classification of CHF. • Features of clinical course and diagnosis of chronic left-and right heart failure of varying degrees . • Methods of diagnosis , the value of instrumental methods. • Differential treatment based on the causes and stages of heart failure. Be able to: • Based on survey data of patients with CHF formulate the final clinical diagnosis and determine the tactics and principles of treatment. Professional orientation of students CHF complicates the majority of cardiovascular diseases and is largely prediction of patient notes and becoming a major factor in mortality. Timely treatment of the underlying disease may prevent the development of CHF. Modern adequate treatment of the heart failure can improve the prognosis and quality of life. Basic knowledge and skills № Discipline To be able to know To be able to do The anatomical structure of the heart 1 Anatomy 2 Histology Structure and functioning myocardium 3 Biochemistry Fundamentals of myocardial metabolism and cardiac contraction muscle 4 Pathophysiology Mechanisms of heart failure, the role of the kidneys and endocrine system 5 Propedevtika internal diseases Semiotics heart failure of different stages and forms Evaluate the clinical, instrumental and laboratory tests Plan for practical lesson № Elements of practical employments 1. Verification of present's students 5 2. Entrance control and his analysis 15 Time(minutes) 3. * Distributing patients for Supervision ( card or clinical tasks ) 10 4. * Review patients or study of educational hospital chart 40 5. Discussion of findings, formulation of previous diagnosis, determination of methods of additional inspection of patient, interpretation of their results, formulation of final diagnosis and plan of treatment 50 6. Exercises with clinical formulations for solving clinical situation tasks 20 7. Output control of knowledge and its evaluation 15 8. Results and final assessment of knowledge and skills of students and tasks to self- preparation for the next lesson 5 Note: * - in the case of patients absence in clinical, practice can be made in the form of preparation and decision of situational tasks. List of theoretical issues addressed in class 1. The main causes of heart failure . 2. Pathogenesis of disorders of the central and peripheral hemodynamics in various forms ( leftand right heart ). Systolic and diastolic dysfunction. The role of the kidneys and endocrine factors. 3. Classification of CHF. Concept stage heart failure and functional class of the patient. 4. Features of clinical course and diagnosis of chronic left-and right heart failure of varying degrees. 5. Methods of diagnosis , the value of instrumental methods. 6. Differential treatment based on the causes and stages of heart failure. Methods of practical classes * After reviewing the present teacher carries out writing the input control background knowledge (added a set of 15 of tests in accordance with the number of students). Teacher carries out the distribution of students for supervision of patients. № Task 1. To provide In a survey reveal: supervision of 1. Symptoms of chronic patients diagnosed circulatory disorders (clinical with heart failure and more) Instructions a student 2. Availability of the reasons that led to the development of heart failure 3. Characteristic changes in heart failure echocardiography, x-ray examination, in laboratory data Note teacher for students Pay particular attention to: • The existence of identified complaints and objective data • the disease, leading to heart failure, quality of treatment of the underlying disease • the availability and duration of changes in x-ray examination and echocardiography • determine the amount of tactics and treatment of heart failure Teachers work according to the plan of studies, spend the weekend at the end of the control knowledge. Before the end of class the teacher sums up the results of his studies on the assessment of each student and announce the topic of the next session. Forms and methods of selfTests 1. Specify the most characteristic systolic dysfunction changes we have identified in echocardiography: A. Mitral valve insufficiency. B. Reduced ejection fraction. C. Increased heart cavities. D. Thickening of the walls of the myocardium. E. Reducing heart cavities. 2. Specify the most typical for left ventricular failure changes we have identified in X-ray study of the chest cavity: A. Cardiomegaly. B. Increased vascular pattern. C. The increase in the left ventricle. D. The increase in the right ventricle. E. The expansion of the aorta. 3. Which drug can most effectively reduce the degree of secondary hiperaldosteronemi in CHF. A. Atenolol. B. Veroshpiron. C. Enalapril. D. Consists of digoxin. E. Furosemide. Situational tasks 1. The patient, 53 years, engineer, complaining of shortness of breath at the slightest exertion , swelling of the legs, heaviness in the right upper quadrant, an attack of breathlessness at night. In the 50 years suffered a myocardial infarction, 3 months began to notice shortness of breath, and a year later - the swelling. Objectively: general condition - moderate. Cyanosis of lips, swelling of the legs. The apical impulse is common, abnormal pulse determined in 5- 6th intercostal space 2 cm from the outside of the midclavicular line. Cardiac deaf. Heart rate - 100 per min. BP 140/90 mm Hg. Liver 4 cm below the right upper quadrant. Radiological findings: heart extended to the left and down, determined paradoxical pulse. ECG - focal cicatricial changes in the anterior wall of the left ventricle. Formulate a diagnosis. Identify tactics and treatments. What is the prognosis of the patient? 2. Woman, age 45, for 15 years suffering from chronic glomerulonephritis. Blood pressure within 200-180/105-110 mm Hg. Complained to the appearance of edema of the lower extremities, weakness, shortness of breath during severe stress, night cough. The blood creatinine - 160 mg/dL, albumin – 55 g/l. In urine daily proteinuria – 0,9 g/l. When echocardiographic ejection fraction (EF) - 35 %. Specify the most likely diagnosis. Is there a need for differential diagnosis? Your tactics in the management of patients. Visual material 1. Tables and slides to the classification of heart failure. 2. Videotape of echocardiography heart in CHF. 3. Sets of radiographs, ECG. 4. Tests case studies. Sources of information Basic: Therapy. Course of lectures. Simferopol. -2003.- 444p. Additional: 1. Harrison's Principles of Internal Medicine 18th edition. .org) 2. ESC Guidelines. Cardiovascular medicine. (Www.escardio.org / guidelines) Individual Students Program topics Explore: • The main causes of heart failure. • Pathogenesis of disorders of the central and peripheral hemodynamics in various forms (leftand right heart). Systolic and diastolic dysfunction. The role of the kidneys and endocrine factors. • Classification of CHF. Concept stage heart failure and functional class of the patient. • Features of clinical course and diagnosis of chronic left-and right heart failure of varying degrees. • Methods of diagnosis, the value of instrumental methods.