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Name ______________________________ Class ___________________ Date __________________ Skills Worksheet Test Prep Pretest In the space provided, write the letter of the term or phrase that best completes each statement or best answers each question. _____ 1. Large cells are difficult to maintain. How do cells overcome this problem? a. They double their DNA. c. They take in more nutrients. b. They coil DNA around proteins. d. They undergo cell division. _____ 2. How do chromosomes of eukaryotes compare with chromosomes of prokaryotes? a. Eukaryotes have a single chromosome, whereas prokaryotes have a number of chromosomes. b. Eukaryotes have chromosomes in the form of a ring, whereas prokaryotes have condensed chromatin in their chromosomes. c. Eukaryotes have chromosomes made of DNA and proteins in a condensed form, whereas prokaryotes have a twisted loop of DNA. d. Both (a) and (b) _____ 3. DNA is coiled in chromosomes so it can a. be packed into a small space. b. wind around the essential proteins. c. can code for RNA and proteins. d. form a centrosome. _____ 4. What do all cells need to do before they begin to divide? a. form a daughter cell c. uncoil their DNA b. form a cell plate d. copy their DNA _____ 5. In which order do the four stages of mitosis occur? a. anaphase, interphase, prophase, and telophase b. prophase, anaphase, metaphase, and telophase c. interphase, prophase, anaphase, and telophase d. prophase, metaphase, anaphase, and telophase _____ 6. During which phase of mitosis do chromatids line up along the equator of the dividing cell? a. anaphase c. interphase b. metaphase d. prophase _____ 7. Which of these structures is found only in a dividing animal cell and not in any other type of dividing cell? a. centrioles c. a spindle b. centrosomes d. sister chromatids Original content Copyright © by Holt, Rinehart and Winston. Additions and changes to the original content are the responsibility of the instructor. Holt Biology 22 Cell Growth and Division Name ______________________________ Class ___________________ Date __________________ Test Prep Pretest continued _____ 8. How does cytokinesis in animal cells differ from cytokinesis in plant cells? a. In animal cells, the loop of DNA attaches to the cell membrane, whereas in plant cells it does not. b. In animal cells, the formation of the cell membrane involves vesicles, whereas in plant cells it does not. c. In animal cells, protein threads pinch the dividing cell in half, whereas in plant cells a cell plate forms down the middle of the dividing cell. d. Both (a) and (b) _____ 9. What slows the rapid cell division of cells healing a cut in the skin? a. the need to copy DNA b. the need to renew the tissues c. contact with other skin cells d. contact with vesicles in the middle of the cell _____ 10. How does a cell ensure that no mistakes occur in the DNA when the cell is dividing? a. Environmental signals influence the cell cycle. b. Protein signals from nearby cells affect a dividing cell. c. There is a checkpoint during mitosis. d. There is a checkpoint before mitosis begins. Complete each statement by writing the correct term in the space provided. 18. A(n) ______________________ is a segment of DNA that codes for RNA and protein. 19. The material that makes up chromosomes in eukaryotic cells and which is formed of DNA and protein is called ______________________. 22. Sister chromatids attach to each other in the region called the ______________________. 23. ______________________ is a group of diseases caused by uncontrolled cell growth. Original content Copyright © by Holt, Rinehart and Winston. Additions and changes to the original content are the responsibility of the instructor. Holt Biology 23 Cell Growth and Division Name ______________________________ Class ___________________ Date __________________ Questions 24–31 refer to the sequence below. 24. The sequence above represents the ____________________ ______________________. 25. The S in the sequence represents the phase in which ___________________ occurs. 26. Phases G1, S, and G2 in the sequence above are collectively called ______________________. 27. During ______________________, a cell nucleus divides into two separate nuclei. _______________________________________________________________ Original content Copyright © by Holt, Rinehart and Winston. Additions and changes to the original content are the responsibility of the instructor. Holt Biology 24 Cell Growth and Division Name ______________________________ Class ___________________ Date __________________ Skills Worksheet Test Prep Pretest Complete each statement by writing the correct term or phrase in the space provided. 1. Asexual reproduction limits ______________________ diversity. 2. Spermatogenesis produces ______________________ sperm cells. 4. In the haploid life cycle, gametes are produced by ___________, and the zygote is produced by ______________________. 5. When corresponding portions of chromatids on two homologous chromosomes change places, ______________________-______________________ has occurred. 6. Only one ovum is produced by ______________________. 7. In plants that have alternation of generations, the haploid ______________________ produces the gametes. 8. Increased genetic variation often helps organisms withstand changes in the ______________________. 9. Meiosis in plants often produces ______________________, haploid cells that later lead to the production of gametes. 10. Crossing-over and _________________ __________________ produce genetic diversity. 11. The 22 pairs of chromosomes in human somatic cells that are the same in males and females are called ______________________. 12. The human chromosomes that determine an individual’s sex are called the ______________________ ______________________. Original content Copyright © by Holt, Rinehart and Winston. Additions and changes to the original content are the responsibility of the instructor. Holt Biology 25 Cell Growth and Division Name ______________________________ Class ___________________ Date __________________ Test Prep Pretest continued Questions 11–14 refer to the figure below. 13. The process shown above is called ______________________. 14. In the process shown above, label A refers to ______________________. 15. In the process shown above, label B refers to ______________________ and ______________________. 16. In the process shown above, label C refers to ______________________. Read each question, and write your answer in the space provided. 19. What is the difference between anaphase I and anaphase II? Why is the difference significant? _______________________________________________________________ _______________________________________________________________ _______________________________________________________________ _______________________________________________________________ _______________________________________________________________ _______________________________________________________________ _______________________________________________________________ 21. Describe the advantages of sexual reproduction. _______________________________________________________________ _______________________________________________________________ _______________________________________________________________ _______________________________________________________________ _______________________________________________________________ _______________________________________________________________ Original content Copyright © by Holt, Rinehart and Winston. Additions and changes to the original content are the responsibility of the instructor. Holt Biology 26 Cell Growth and Division Name ______________________________ Class ___________________ Date __________________ Test Prep Pretest 1. d 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 31. 32. 33. 16. 7; strand of fully condensed DNA ready c for cell division a 17. 4; structural unit of chromatin made up of d DNA wrapped around a histone core d 18. gene b 19. chromatin a 20. centrosome c 21. spindle c 22. centromere d 23. Cancer 3; group of eight histones that form a disc 24. cell cycle that DNA wraps around 25. DNA synthesis (or DNA replication or 1; nucleic acid that contains the genetic code DNA copying) 6; loops formed of nucleosome cords that 26. interphase are attached to a protein scaffold 27. mitosis 5; string of nucleosomes coiled to form a 28. cytokinesis cord 30 nm in diameter 29. M, C 2; protein molecule found in the 30. G1, S chromosomes of eukaryotic cells Each cell enters the G1 phase of interphase, during which it grows rapidly and builds more organelles. Cell size is limited by two things: (1) the ability of the cell to exchange substances with the environment and to get substances to where they are needed within the cell and (2) the ability of the cell to copy the DNA instructions to make proteins in a timely fashion. A tumor is a mass of defective cells that have an uncontrolled cell cycle. A benign tumor does not spread to other parts of the body. Benign tumors are usually easy to remove. Cells in malignant tumors invade and destroy nearby healthy tissues and organs; they can also break loose and spread to other parts of the body. Test Prep Pretest 1. genetic 10. independent assortment or random 2. four fertilization 3. budding, binary fission 11. autosomes 4. mitosis, fusion 12. sex chromosomes 5. crossing-over 13. meiosis 6. oogenesis 14. prophase I 7. gametophyte 15. anaphase I 8. environment 16. metaphase II 9. spores 17. The formation of male and female gametes involves meiosis. In spermatogenesis, meiosis produces four sperm cells. In oogenesis, however, the cytoplasm divides unequally and meiosis produces three polar bodies that do not survive and one egg cell. 18. In binary fission, the parent divides into two or more individuals of the same size. In fragmentation, the parent’s body breaks into several pieces that grow into complete individuals. In budding, new individuals split off from existing ones. In parthenogenesis, females lay unfertilized eggs that develop into offspring. 19. In anaphase I, the two chromatids of each chromosome remain attached at their centromeres as the homologous pairs move to the poles of the cell. In anaphase II, the centromeres divide and the chromatids Original content Copyright © by Holt, Rinehart and Winston. Additions and changes to the original content are the responsibility of the instructor. Holt Biology 27 Cell Growth and Division Name ______________________________ Class ___________________ Date __________________ move to opposite poles of the cell. If the centromeres did not divide and split the paired chromosomes during anaphase II, the new cells would not be haploid. 20. In the haploid life cycle, haploid cells develop into haploid multicellular individuals that produce gametes through mitosis. A diploid zygote forms through fusion of gametes, undergoes meiosis immediately, and creates new haploid cells. In the diploid life cycle, haploid gametes are produced through meiosis, and they create a diploid zygote through fertilization. The individual that results from the zygote remains diploid and occupies most of the diploid life cycle. 21. An advantage of sexual reproduction is that it provides a powerful means of quickly making different combinations of genes among individuals. This genetic diversity may increase the ability of a species to adapt and succeed. 22. A frog somatic cell is diploid and therefore has twice the number of chromosomes of the haploid frog egg cell. Original content Copyright © by Holt, Rinehart and Winston. Additions and changes to the original content are the responsibility of the instructor. Holt Biology 23 Cell Growth and Division