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Transcript
‫بسم هللا الرحمن الرحيم‬
Choose the correct answer for questions (1 – 90 )
1. Increased serum a level of which of the following is associated with a decreased risk of
atherosclerosis?
a) Cholesterol
d) Triglyceride
b) LDL
e) VLDL
c) HDL
2. The active ingredient in Tinasil is
a) Fexofenadine
d) Dimethindene
b) Naftifine
e) Amlodipine
c) Terbinafine
3. The manufacturer of Tinasil is
a) Birzeit
d) Jerusalem
b) Pharmacare
e) Gama
c) Beit jala
4. Tinasil is
a) Antiangina
b) Anti-inflammatory
c) Antiviral
d) Antimalaria
e) Antifungal
5. Which of the following have been shown to be effective in the acute management of
digitalis toxicity ?
a) Cholestyramine resin
d) A and B
b) Fab fragment antibody
e) All
c) Potassium administration
6. What are the most common adverse effects of anticonvulsive drugs?
a) Headache and dizziness
b) Gastrointestinal symptoms
c) Adverse effects on appetite and body weight
d) Alteration of cognition and mentation
e) All of the above
7. in the emergency department, the preferred first-line therapy for asthma exacerbation is
a) theophylline
d) a corticosteroid
b) a B-agonist
e) cromolyn sodium
c) an antihistamine
8. Current criteria used in the diagnosis of diabetes mellitus (DM) include all of the
following symptoms EXCEPT
a) Fasting hyperglycemia
d) polydipsia
b) Polyuria
e) tinnitus
c) weight loss
9. Sulfonylurease are a primary mode of therapy in the treatment of
a) Insulin-dependent (type 1) diabetes mellitus (IDDM) patients
b) Diabetic patients experiencing severe hepatic or renal dysfunction
c) Diabetic pregnant women
d) Patients with diabetic ketoacidosis
e) Non-insulin-dependent (type 2) DM (NIDDM) patients
1
10. Exjade is an antidote that is used in case of --------------- poisoning:
a) Iron
d) Calcium
b) Heparin
e) None of the above.
c) Paracetamol
11. The thyroid gland normally secretes which of the following substances into the serum ?
a) Thyrotropin-releasing hormone (TRH)
b) Thyrotropin (thyroid-stimilating hormone)
c) Diiodothyronine (DIT)
d) Thyroglobulin
e) Thyroxine (T4)
12. Potential adverse effects associated with aspirin include all of the following EXCEPT:
a) Gastrointestinal ulceration
b) Renal dysfunction
c) Enhanced methotrexate toxicity
d) Cardiac arrhythmias
e) Hypersensitivity asthma
13. All of the following facts are true about nonsteroidal anti-inflammatory drugs (NSAIDs)
EXCEPT
a) They are antipyretic
b) There is a ceiling effect to their analgesia
c) They can cause tolerance
d) They do not cause dependence
e) They are anti-inflammatory
14. A common adverse effect of thrihexyphenidyl is:
a) Insomnia
b) Nausea and vomiting
c) Dry mouth and urinary retention
d) Depression
e) Anorexia
15. Which inhibits monoamine oxidase (MAO)?
a) Benztropine
d) Pramipexole
b) Bromocriptine
e) Selegiline
c) Tolcapone
16. How does carbidopa affect levodopa ?
a) Slows the release from presynaptic neurons
b) Prevents the excretion of dopamime receptors
c) Increases stimulation of dopamime receptors
d) Decreases tolerance to normal doses
e) Inhibits the peripheral conversion to dopamine
17. Acetylcysteine is used to treat overdoses of
a) Benadryl
d) Aspirin
b) Ayds
e) No Doz
c) Acetaminophen
2
18. Long-acting topical nasal decongestants share which of the following properties?
a) They are sympathomimetic agents
b) They are likely to produce rebound congestion with prolonged use
c) Their effects last for more than 24 hours
d) A and B
e) B and C
19.
Which of the following drugs is available over-the-counter for the treatment of nausea
and vomiting?
a) Dimenhydrinate
d) Prochlorperanzine
b) Perphenazine
e) Scopolamine
c) Danthron
20. Predisposing causes of hemorrhoids include all of the following EXCEPT
a) Prolonged standing
d) high-fiber diet
b) heredity
e) inadequate fluid intake
c) diarrhea
21. How many grams of water are needed to make 150 g of a 4% w/w solution of potassium
acetate?
a) 100
d) 135
b) 130
e) 144
c) 156
22. The term bioavailability refers to the
a) Relationship between the physical and chemical properties of a drug and the systemic
absorption of the drug
b) Measurement of the rate and amount of therapeutically active drug that reaches the
systemic circulation
c) Movement of a drug into the body tissues over time
d) Dissolution of a drug in the gastrointestinal tract
e) Amount of drug destroyed by the liver prior to systemic absorption from the
gastrointestinal tract
23. The passage of drug molecules across a cell membrane from a region of high drug
concentration to a region of low drug concentration is known as
a) Active transport
b) bioavailability
c) biopharmaceutics
d) passive diffusion
e) pinocytosis
24. The following patient instructions are necessary when prescribing Co-Trimoxasole
suspension:a) Shake well before use.
b) Take medicine with plenty of fluids.
c) Exposure to sunlight may cause adverse reactions.
d) a + b
e) All of the above
25. All of the following drugs are classified as Anti-Viral except:a) Amantadine
d) Amikacin
b) Ribavirin
e) Peginterferon alfa-2a
c) Acyclovir
3
26. The following Tetracycline has the longest duration of action
a) Doxycycline
d) Minocycline
b) Tetracycline
e) Oxytetracycline
c) Demeclocycline
27. The following drug is classified as a narcotic antagonist
a) Butorphenol
d) Naloxone
b) Buprenorphine
e) Sufentanil
c) Nalbuphine
28. Which of the following is true concerning regular insulin:
a) It is a clear product.
b) It may be administered either SC or IV.
c) It is a short acting insulin.
d) It is a rapid acting insulin.
e) All of the above.
29. Dormicum contains the following active ingredient:
a) Meropenem
d) Propofol
b) Midazolam
e) Promethazine
c) Bupivacaine
30. Norvasc is manufactured by:
a) Pfizer
b) Wyeth
c) Novartis.
d) Astra Zeneca
e) Abbot
31. The active ingredient in Lioresal is:
a) Propofol
b) Baclofen
c) Leucovorin
d) Levofloxacin
e) Lithium carbonate.
32. When considering the appropriateness of Metformin monotherapy for a patient
type II diabetes mellitus, relevant patient factors to consider include:
I. Obesity
II. Renal dysfunction.
III. Thyroid function.
a) I only
d) II and III only
b) III only.
e) I, II and III.
c) I and II only.
33. Auxiliary labeling for Clarithromycin suspension includes which of the following:
a) Shake well before use.
b) Take with plenty of fluids.
c) Avoid prolonged exposure to sunlight.
d) Keep refrigerated.
e) May cause discoloration of urine.
4
with
Read the following prescription carefully, then answer questions (34-36)
Mepral 20 mg cap
20mg I x dly
34) The active ingredient in the drug Mepral is:
a) Metronidazole.
d) Esomeprazole.
b) Sulpride.
e) Famotidine
c) Omeprazole
35) Mepral is manufactured by:
a) JPH
b) BPC
c) Pharmacare
d) JCL
e) Belpharm
36) According to the prescription the drug should be administered as follows:
a) One tab daily.
d) One tab four times daily.
b) One tab twice daily.
e) None of the above.
c) One tab three times daily.
37) Which of the followings is not correct:
a) Orazole = Ketoconazole
b) Rafassal = Sulphasalazine.
c) Cellecept = Cyclosporine.
d) Rocephin = Ceftriaxone.
e) Zitrocin = Azithromycin.
38) Read the following prescription carefully then calculate the volume of the solution that
the patient need for 20 days:-
Rx
a)
b)
c)
d)
e)
Morphine Sulphate Solution
5mg/ml q 4h
For 20 days
20ml
60ml
80ml
100ml
120ml
39) All of the following drugs should be avoided during pregnancy except:a) Narcotics
b) Barbiturates
c) Diazepam
d) Acetaminophen
e) None of the above
40) Pareteral products with an osmotic pressure greater than that of blood or 0.9% sodium
chloride are referred to as:
a) Isotonic solutions
b) Hypertonic solutions
c) Hypotonic solutions
d) Iso-osmotic solutions
e) Neutral solutions
5
41) Molarity is defined as:a) Gram molecular weight of solute in 1 liter of solution
b) Gram equivalent weight of solute in 1 liter of solution
c) Saturated solution of a solute in 1 liter of solution
d) ml of solvent required to dissolve 10 grams of solution
e) Supersaturated solution of a solute
Read the following prescription then answer questions from (42-47)
Zitrocin 200mg/5ml Pwdr for Susp
10mg/Kg dly for III days
15ml bottle
42) Zitrocin is the trade name for the following drug:
a) Amoxycillin
d) Roxithromycin
b) Cefuroxin
e) Ceftriaxone
c) Azithromycin
43) Zitrocin is classified as a:
a) Penicillin antibiotic
b) Cephalosporin antibiotic.
c) Macrolide antibiotic
d) Tetracycline
e) Quinalone
44) Zitrocin is manufactured locally by the following company:a) JPH
d) Belpharm
b) BPC
e) JCL
c) Pharmacare
45) A drug that contains the same active ingredient as Zitrocin is:
a) Augmentin
d) Zinacef
b) Azenil
e) Rulid
c) Zinnat
46) According to the prescription, the single daily dose for a child weighing 20 Kg is:a) 2.5 ml
d) 15 ml
b) 5 ml
e) None of the above
c) 10 ml
47) According to the prescription, the total dose for a child weighing 20 Kg is:a) 15 ml
d) 30 ml
b) 20 ml
e) 35 ml
c) 25 ml
48) Factors that determine bioequivalence of two brands of a drug include:I. The taste of the preparations
II. The physical appearance of the preparations.
III. Pharmacokinetic parameters of the preparations.
a)I only
d) I and II only
b) III only
e) II and III only
c) I, II, and III
6
49) Clofibrate is classified as a/an:
a) ACE inhibitor
b) Lipid lowering agent
c) Antihypertensive agent
d) Beta blocker
e) Immuno-suppressive agent
50) The active ingredient in the drug Prograf is:
a) Cyclosporine
d) Piroxicam
b) Tacrolimus
e) Sirolimus
c) Tamoxifen
51) Prednisolone may cause all of the following effects except:a) Skeletal muscle weakness
b) Hypoglycemia
c) Sodium retention
d) Peptic ulceration
e) Lowered resistance to infections
52) A package insert lists a drug dose for a neonate as being 10 mcg/kg/ day. The age range for a neonate
is considered to be :
a) birth to 1 month
b) 1 month to 6 months
c) 1 month to 1 year
d) birth to 1 week
e) 1 year through 5 years
53) INR:
1. is monitored in patients with arthritis
2. is monitored in patients receiving warfarin
3. stands for international normalised ratio
a) 1, 2, 3
d) 2, 3 only
b) 1, 2 only
e) 1 only
c) 3 only
54) When administered at the same time , antacids can decrease the therapeutic efficacy of
which of the following drugs ?
a) Sucralfate
d) B and C
b) Ranitidine
e) A , B and C
c) Cimetidine
55) Specific therapy for an acute extrapyramidal reaction to chlorpromazine is
a) Physostigmine
d) bethanechol
b) Diphenhydramine
e) propranolol
c) metoclopramide
56) Rectal suppositories intended for adult use usually weight approximately
a) 1 g
d) 3 g
b) 2 g
e) 4 g
c) 5 g
57) All of the following preparations contain alcohol EXCEPT
a) Syrup USP
b) Terpin hydrate elixir USP
c) Aromatic ammonia spirit USP
d) Green soap tincture USP
e) Eriodictyon fludextract NF
7
58) Which of the following capsule sizes has the smallest capacity?
a) 5
d) 1
b) 4
e) 0
c) 000
59) A satisfactory suppository base must meet all of the following criteria EXCEPT
a) It should have a narrow melting range
b) It should be nonirritating and nonsensitizing
c) It should dissolve or disintegrate rapidly in the body cavity
d) It should melt below 30 C
e) It should be inert
60) A prescription label should contain all of the following EXCEPT
a) Quantity dispensed
b) Lot number
c) Patient diagnosis
d) Expiration date
e) Physician name
61) Which of the following substances when present in urine is the most likely positive sign
of pregnancy?
a) Thyroid-stimulating hormone (TSH)
b) Corporation (ACTH)
c) Human Chorionic gonadotropin (HCG)
d) Interstitial cell-stimulating hormone (ICSH)
e) Protamine zinc insulin (PZI)
62) All of the following substances are endogenous tropic hormones secreted by the pituitary
gland EXCEPT
a) somatotropin
b) human chorionic gonadotropin (HCG)
c) follicle-stimulating hormone (FSH)
d) thyroid-stimulating hormone (TSH)
e) corticotrophin (ACTH)
63) The pH value is calculated mathematically as the
a) Log of the OH- concentration
b) Negative log of the OH- concentration
c) Log of the H+ concentration
d) Negative log of the H+ concentration
e) Ratio of H+/OH- concentration
64) Which of the following tissues has the greatest capacity to biotransform drugs?
a) Brain
d) liver
b) Kidney
e) lung
c) Skin
65) The active ingredient in Trovan is
a) Simvastatin
b) Atrovastatin
c) Fluvastatin
d) Pravastatin
e) Ciprofibrate
8
66) The manufacturer of Trovan
a) Birzeit
b) Pharmacare
c) Gama
d) Beit jala
e) Jerusalem
67) Which brand name – generic name combinations are correct?
a) Feldene – meclofenamate.
b) Vioxx – celecoxib.
c) Naprosyn – naproxen.
d) a and b.
e) b and c.
68) Which substance should be used in a case of overdosage with methotrexate (MTX)?
a) Brewer's yeast.
b) Leucovorin.
c) Para- aminobenzoic acid.
d) Sulfisoxazole.
e) Trimethoprim.
69) OTC cold and allergy products often contain a combination of active ingredients. An
OTC product that contains guaifenesin, pseu-doephedrine, and dextromethorphan would have
a) Antihistamine, decongestant, and antitussive activity.
b) Expectorant, decongestant, and antitussive activity.
c) Demulcent, antitussive, and antihistamine activity.
d) Expectorant, demulcent, and antitussive activity.
e) Antitussive, decongestant, and demulcent activity.
70) A friend of yours has very severe hypertension and asks about a drug her doctor wishes to
prescribe. Her physician has explained that this drug is associated with tachycardia and fluid
retention (which may be marked) and increased hair growth. Which of the following is most
likely to produce the effects your friend has described?
a) Captopril
d) Minoxidil
b) Guanethidine
e) Prazocin
c) Propranolol
71) Which drug is a substituted imidazole for treating many systemic fungal infections and is
an effective agent taken orally?
a) Butoconazole.
b) Clotrimazole.
c) Ketoconazole.
d) Miconazole.
e) Nystatin.
72) True comparisons of Trufen to Otamol include
a) Otamol has less anti- inflammatory activity than Trufen
b) Otamol is contraindicated in children because they are susceptible to Reye's
syndrome.
c) Otamol l irritates the gastrointestinal tract more than Trufen
d) a & b
e) c & a
9
73) A visitor from another city comes to your pharmacy complaining of incessant cough. He
has diabetes and hypertension and has recently taking a new antihypertensive medication.
The most likely cause of his cough is
a) Enalapril
b) Losartan
c) Minoxidil
d) Propranolol
e) Verapamil
74) Which of the following are true regarding Helicobacter pylori?
a) It is present in the majority of patients with duodenal ulcer.
b) H. pylori eradication can cure peptic ulcer disease and reduce ulcer recurrence.
c) Treatment of active duodenal ulcer is best managed with a combination of
antisecretory therapy plus appropriate antibiotic (s).
d) A & c
e) All of above.
75) Which of the following matches is not true?
a) Coxib – etoricoxib
b) Sinagra - Sildenafil
c) Adcef - Cefdinir
d) Movalis - Meloxicam
e) Zydex – fusidic acid
76) Enythropoietin procrit is used in chronic renal failure to treat?
a) Peripheral neuropathy.
b) Anemia.
c) Hyperphosphatemia.
d) Metabolic alkalosis.
e) Hyperuricemia
77) The active ingredient in Exforge is
a) Amlodipine
b) Valsartan
c) Nifedipine
d) a + b
e) a + c
78) The manufacturer of Exforge is
a) Pfizer
b) Glaxo
c) Novartis
d) CTS
e) Dexxon
79) Lucast (montelukast sodium) is indicated for
a) prophylaxis of asthma
b) chronic treatment of asthma
c) relief of symptoms of seasonal allergic rhinitis
d) a + b
e) all of the above
10
80) The manufacturer of Lucast is
a) Birzeit
b) Pharmacare
c) Beit jala
d) Jerusalem
e) Gama
81) Nystatin suspension is used as prophylaxis against which organism?
a) Histoplasma capsulatum.
b) Candida albicans.
c) Pneumocystis carinii.
d) Pseudomonas aeruginosa.
e) Staphylococcus aureus
82) A patient allergic to penicillin group of antibiotics has to avoid
a) Klacid
b) Azenil
c) Doxacin
d) Denacine
e) Drypen
83) The active ingredient in Acidex Complete
a) Famotidine
b) Magnesium Hydroxide
c) Calcium Carbonate
d) b + c
e) All of the above
84) The manufacturer of Acidex Complete is
a) Birzeit
b) Pharmacare
c) Beit jala
d) Jerusalem
e) Gama
85) The active ingredient in Crestor is
a) Bezafibrate
b)Colestipol
c) Rosuvastatin
d) Fluvastatin
e) Atrovastatin
86) The manufacturer of Crestor is
a) Pfizer
b) Glaxo
c) Novartis
d) Lapidot
e) AstraZeneca
11
87) The most likely cause of death associated with an overdose of acetaminophen is
a) Arrhythmia
b) Hemorrhagic stroke
c) Liver Failure
d) Noncardiogenic pulmonary edema
e) Ventilatory failure
88) Aspirin overdose is characterized by a syndrome of
a) Bone marrow dysfunction and possibly aplastic anemia.
b) Fever, hepatic dysfunction and encephalopathy
c) Hyperthermia, metabolic acidosis, and coma
d) Rapid, fulminant hepatic failure
e) Rash, interstitial nephritis and acute renal failure
89) Ingestion of which of the following vitamins should be avoided by a patient taking the
oral anticoagulant warfarin?
a) Vitamin A
b) Vitamin B
c) Vitamin D.
d) Vitamin E.
e) Vitamin K.
90) Creatinine clearance is a measurement of :
a) Glomerular filtration rate (GFR).
b) Active tubular secretion.
c) Muscle metabolism.
d) Hepatic function.
e) Effective renal plasma flow.
:)911-19( ‫أجب بنعم أو ال على األسئلة من‬
)
(
.‫ يجوز للصيدلي أن يكون مالكا ألكثر من مؤسسة صيدالنية واحدة‬.19
)
(
.‫ متر مربع‬04 ‫ يجب أن ال تقل مساحة الصيدلية عن‬.19
)
(
.‫ مستودع األدوية مخصص لبيع األدوية بالجملة و المفرق ألي كان‬.13
‫ شهرا فقط حسب األصول بسبب سفره إلى الخارج و عندما رجع له الحق‬91 ‫ صيدلية أغلقها صاحبها لمدة‬.10
)
(
.‫بإعادة فتحها و ممارسة عمله‬
)
(
‫ يجوز أن يكون تاريخ انتهاء الدواء مختوما بالحبر أو مطبوعا من قبل الشركة الصانعة‬.11
)
(
.‫ ال يجوز أن يكون للصيدلية العامة باب فرعي آخر يتصل بمنزل الصيدالني المسئول‬.19
) (
.‫ يجوز حقن اإلبر في الصيدلية من قبل أي كان‬. 19
) (
.‫ ال يجوز أن يكون باب الصيدلية الخاصة التابعة لجمعية خيرية على الشارع العام‬.19
.‫ يجوز للصيدلي المالك و المسئول عن الصيدلية العمل كمندوب دعاية باإلضافة إلى عمله في الصيدلية‬.11
(
)
)
(
.‫ يلغى الترخيص الممنوح من الوزارة في حال تم بيع الصيدلية دون علم و موافقة الوزارة‬.944
‫مع تمنياتنا لكم بالنجاح‬
12