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Review: purpose of the endocrine system endocrine glands hormones produced and their purpose Oct 1110:27 AM Negative Feedback Loop a process that detects and reverses changes from normal body constants (homeostasis) involves a receptor (ex. sensory organ), an integrator (ex. hypothalamus) and an effector (ex. gland) an example would be the hypothalamus pituitary complex Oct 1110:31 AM 1 Example of Negative Feedback Loop Hypothalamuspituitary complex the hypothalamus is the part of the brain that controls the endocrine system this is due to its control of the pituitary gland (the master gland) the pituitary gland has two parts: the anterior pituitary (front) and the posterior pituitary (back) see page 428 Oct 1110:38 AM Positive Feedback Loop often associated with disease or change (ex. drug addiction) and thus is often rare acts to increase the stimuli and in the case of drugs push the body away from homeostasis an exception is use of oxytocin, a hormone that causes contractions during childbirth each contraction causes the release of more oxytocin until the child is born Oct 1110:34 AM 2 Negative Feedback Mechanism Hypothalamus Releasing Factor (Hormone 1) Pituitary Gland Feedback (excess hormone levels) inhibits release of hormone 1 Stimulating Factor (Hormone 2) Feedback inhibits release of hormone 2 Target Gland Target Hormone Released Oct 1410:18 AM Positive Feedback Mechanism (Oxytocin Loop) Uterine water breaks Pressure Exerted on Cervix Uterine Contractions Increase Increase Oxytiocin Released Oct 1410:30 AM 3 Antagonistic Hormones hormones that work against each other or have opposite effects on the body Ex. insulin and glucagon parathyroid hormone and calcitonin Tropic Hormones hormones that regulate the hormone production of many other hormones Readings: Pages 427 435 Oct 142:56 PM 4