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Transcript
The Hill Card
Jinnie Garrett - Faculty
176453328971892364738736198364818…..AATGCCYNNNAATCG
HT-1/HT-6
CH: QR9/Q5
IQ: 1124/1125, cdA/cdA M: 70/78
RB: 12/18
AA: gdD/gdB CR: B/OC-2, SC-8, CC-3, LC-5, Other-4
___________________________________________________________
IC for DMD
+ XC. M:85:95, RbA/RbA
Hamilton College, Clinton, NY.
2011
Genetic information listed on your Hill Card includes:
HT: Predisposition to hypertension.
Normal alleles – HT-1, 3, 4, 7, Elevated risk – HT-2, 6, 8, Highly elevated – HT-5.
M: Memory. Predicted age of short term memory decline/expected age of dementia onset.
CR: Cancer risk. B/O – breast/ovarian, P – prostate, S – skin, C – colon, L – lung,
On scale 1 (very low) – 10 (almost certain)
Additional information
IC –identified carrier for recessive alleles for DMD (Duschenne Muscular Dystrophy), CS (cystic fibrosis),
TS (Tay-Sach’s), FX (fragile X syndrome)
+XC – additional chromosome added at pre-implantation stage. If you do not have an XC be aware
these were available to your parents at the time of your conception.
RbA= retinoblastoma – tumor suppressor gene.
BRCA1, BRCA2, = normal copies of the breast cancer genes
AUD7 = Auditory transmitter signaling – highly increased likelihood of perfect pitch.
MSC – Myostatin-suppressing variant C – increased aerobic capacity for long distances/times.
MSD - Myostatin-suppressing variant D – increased muscle capacity for strength.
Bear in mind that all genetic identities are really statistical risk factors that are impacted by the person’s
environment and lifestyle.
Your final paper must be a response to the genetic identity given to
you on your “Hill Card” and you must choose a particular position
to argue. Papers that just discuss the topic without taking a position
will be seriously penalized.
There are several possible approaches to choose from – two examples
• Some of you have additional chromosomes that provide copies of
genes that should decrease your predicted risk of undesirable
events (cancer, early memory loss). Are you glad that your parents
chose these modifications? Do you think such genetic
enhancements should be available to the general population?
• Those of you who have genomes that have not been modified to
decrease your risk may discuss whether you would want to have
been modified. Why/ why not?
• *In your paper, you must use at least 6 of the assigned course
readings, which must include both Watson and McKibben