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Transcript
COURSE OVERVIEW
This course is taught to students who have experienced one year of
introductory biology and one year of chemistry.
My students are from very diverse backgrounds which makes this
course an excellent vehicle to transport them through their lives and help
them achieve their goals. The goal of most of my students is a career in
health care or science related fields, which can in turn affect the lives of
others and the planet we all share.
My goal is to give students a conceptual understanding of biology
and how biology topics are very intertwined. I cover every chapter from
Campbell’s Biology and have included listed subtopics from each chapter
from Campbell’s book to demonstrate the subtopics covered in the
course, The course text maps out twelve themes of biology, which are
aligned with the “eight major themes” of biology according to the AP
curriculum. On my list of subtopics, I have listed one or several of the
eight themes of biology in italics as I see them relating to that topic. I
frequently tell students that a topic we have just covered will come back
to “haunt” them.
Topics frequently relate back to evolution which I point out when
we cover translation and the universality of genetic codons and the
phylogenetic order as we move from the very beginning of life on Earth to
the more complex organisms and as organisms interact and natural
selection occurs.
Students apply their knowledge of biology and use critical thinking
to explore environmental and social concerns. When the topic of nutrition
is covered, students do an activity where they are given a fast food menu
and must calculate protein, carbohydrates, fats and total calories for
three meals. For the fourth meal, they must make a nutritionally balanced
meal. Students also do an activity where they must calculate a well
balanced diet for one day and then cut calories while maintaining
nutritional values. Eventually, they get down to 800 calories and an
anorexic diet. We do an activity based on the Donner party and must sort
out and graph data to explain why some lived and some died. These are
very eye opening activities and many swear they are never eating fast
food again.
Environmental issues are other topics whereby students see with
greater clarity how biology addresses environmental and social concerns.
As my students and I are surrounded by the Great Lakes, we have been
and will be profoundly affected by exotic species and pollution being
introduced into our waterways. Students do research on the species
introduced into our lakes and present findings. In previous years, we have
tested the water in a nearby river and reported our findings in conjunction
with other schools to a website at our intermediate school district. This
was also done in conjunction with the We Are Here Foundation.
The ethics of biotechnology also addresses both environmental and
social concerns. As we study genetic engineering, cloning and new
biotechnologies, students must research an issue, such as stem cell
research. Students then debate the pros and cons of the issue and use
their research to back up their claim.
Students have the opportunity to design and conduct a minimum of
two experiments, which are extensions of experiments done in class. They
must gather and analyze their data, write a full lab report and present
their findings.
LABS
Students perform all labs in the AP manual as well as others I have
found over the years. Lab comprises a minimum of twenty-five percent of
our class time. Each lab requires a written lab report.
TEACHING STRATEGIES
When not doing labs and activities, I use PowerPoint lectures with
graphs, photos, illustrations, diagrams, and embedded videos. I use the
module exercises from another biology text that correlates to ours for
students to practice applying their knowledge. Occasionally, pertinent
DVDs may be shown or interactive CDs may be used. I also use a variety
of newspapers, magazines, and some journals on current events in
biology.
2
ASSESSMENT
I use many forms of assessment to measure understanding. Each
chapter has a written test from the text. There are also quizzes, essays,
research papers, lab reports, and a final cumulative exam at the end of
each semester.
BOOKS AND RESOURCES
AP Biology Lab Manual for Students, College Entrance Examination Board,
2001.
AP Biology Lab Manual for Teachers, College Entrance Examination Board,
2001.
Bernstein, Ruth & Bernstein, Stephen, Biology, Wm. C. Brown Publishing,
1996.
BSCS, Biology, A Human Approach, Kendall-Hunt, 1997.
Campbell, Neil, Biology, Benjamin/Cummings Publishing Co., 1996, Fourth
Edition.
Education Development Center, Inc., Insights in Biology – The Matter of
Life, Kendall-Hunt, 1998.
Education Development Center, Inc., Insights in Biology – Traits and Fates,
Kendall-Hunt, 1998.
Lawrence, Sonya, Heidemann, Merle & Straney, Donald, Biological Sciences
111L Lab Manual, Hayden-McNeil Publishing, Inc., 2000.
Liebart, Richard, Student Study Guide for Biology: Concepts &
Connections, Benjamin Cummings, Second Edition, 1997.
Van Hoeck, Kathy, Genetics Lab and Classroom Activities, Flinn Scientific,
Inc., 2001.
3
CONTENT
TOPIC I
Unit I Chemistry of Life (12 days)
Reading + Topics
Chapter 1 Themes of Biology
• Life is organized on many structural levels
• Each level of biological organization has emergent properties
• Cells are an organism’s basic units of structure and function
• The continuity of life is based on heritable information in the form
of DNA
• A feeling for organisms enriches the study of life
• Structure and function are correlated at all levels of biological
organization
• Organisms are open systems that interact continuously with their
environments
• Diversity and unity are the dual faces of life on Earth
• Evolution is the core theme of biology
• Science as a process of inquiry often involves hypotheticodeductive thinking
• Science and technology are functions of society
• Biology is a multidisciplinary adventure
Chapter 2 The Chemical Context of Life
• Matter consists of chemical elements in pure form and in
combinations called compounds
• Life requires about 25 chemical elements
• Atomic structure determines the behavior of an element
• Atoms combine by chemical bonding to form molecules
• Weak chemical bonds play important roles in the chemistry of life
• A molecule’s biological function is related to its shape~relationship
of structure to function
• Chemical reactions change the composition of matter
• Chemical conditions on the early Earth set the stage for the origin
and evolution of life
4
Chapter 3 Water and the Fitness of the Environment
• The polarity of water molecules results in hydrogen bonding
• Organisms depend on the cohesion of water
molecules~interdependence in nature
• Water contributes to Earth’s habitability by moderating
temperatures
• Oceans and lakes don’t freeze solid because ice floats
• Water is the solvent of life
• Organisms are sensitive to changes in pH
• Acid precipitation threatens the fitness of the
environment~science, technology and society/interdependence of
nature
Chapter 4 Carbon and the Molecular Diversity of Life
• Organic chemistry is the study of carbon compounds
• Carbon atoms are the most versatile building blocks of molecules
• Variation in carbon skeletons contributes to the diversity of organic
molecules~evolution
• Functional groups also contribute to the molecular diversity of life
• The chemical elements of life
Chapter 5 The Structure and Function of Macromolecules
• Most macromolecules are polymers
• A limitless variety of polymers can be built from a small set of
monomers
• Organisms use carbohydrates for fuel and building material~energy
transfer
• Lipids are mostly hydrophobic molecules with diverse functions~energy
transfer
• Proteins are the molecular tools for most cellular functions
• A polypeptide is a polymer of amino acids connected in a specific
sequence~relationship of structure to function
• A protein’s function depends on its specific conformation~structure
related to function
• Nucleic acids store and transmit hereditary information~
relationship of structure to function
• A DNA strand is a polymer with an information-rich sequence of
nucleotides
5
•
•
Inheritance is based on precise replication of DNA relationship of
structure to function
We can use DNA and proteins as measures of evolution~evolution
Chapter 6 An Introduction to Metabolism
• The chemistry of life is organized into metabolic pathways~energy
transfers
• Organisms transform energy~energy transfers
• The energy transformations of life are subject to two laws of
thermodynamics
• Organisms live at the expense of free energy
• ATP powers cellular work by coupling exergonic to endergonic
reactions
• Enzymes speed up metabolic reactions by lowering energy barriers
• Enzymes are substrate-specific~structure related to function
• The active site is an enzyme’s catalytic center
• A cell’s chemical and physical environment affects enzyme
activity~structure related to function
• Metabolic order emerges from the cell’s regulatory systems and
structural organization~regulation
• The theme of emergent properties is manifest in the chemistry of
life
LABS
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AP Lab 2 Enzyme Catalysis
Food Analysis-Testing Some Common Foods Lab (Flinn Scientific)
Milk is a Natural Lab-Biology, Chemistry, and Nutrition (Flinn Scientific)
Mystery Food Lab
Little Miss Muffet Discovers Chy-Max Cheese Making Lab (Flinn
Scientific)
Student designed extension of cheese making lab
UNIT II THE CELL (18 days)
Reading + Topics
Chapter 7 Tour of the Cell
• Microscopes provide windows to the world of the cell
• Cell biologists can isolate organelles to study their functions
• A panoramic view of the cell
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•
The nucleus is a cell’s genetic library~relationship of structure to
function
Ribosomes build a cell’s proteins~regulation
Many organelles are related through the endomembrane system
The endoplasmic reticulum manufactures membranes and performs
many other biosynthetic functions~regulation
The Golgi apparatus finishes, sorts, and ships many products of the
cell~regulation
Lysosomes are digestive compartments~regulation
Vacuoles have diverse functions in cell maintenance~regulation
Peroxisomes consume oxygen in various metabolic
functions~regulation
Mitochondria and chloroplasts are the energy transformers of
cells~regulation/energy transfer
The cytoskeleton provides structural support and functions in cell
motility~regulation
Plant cells are encased by cell walls
The extracellular matrix of animals cells functions in support,
adhesion, movement and development~regulation
Intercellular junctions integrate cells into higher levels of structure
and function~regulation/relationship of structure to function
The cell is a living unit greater than the sum of its
parts~interdependence of nature
Chapter 8 Membrane Structure and Function
• Membrane models have evolved to fit new data: science as a
process
• A membrane is a fluid mosaic of lipids, proteins and
carbohydrates~relationship of structure to function
• A membrane’s molecular organization results in selective
permeability~relationship of structure to function
• Passive transport is diffusion across a membrane~regulation
• Osmosis is the passive transport of water~regulation
• Cell survival depends on balancing water uptake and loss~regulation
• Specific proteins facilitate the passive transport of selected
solutes~relationship of structure to function
• Active transport is the pumping of solutes against their
gradients~relationship of structure to function/regulation
• Some ion pumps generate voltage across membranes
7
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•
In cotransport, a membrane protein couples the transport of one
solute to another~relationship of structure to function
Exocytosis and endocytosis transport large molecules~regulation
Specialized membrane proteins transmit extracellular signals to the
inside of the cell~interdependence in nature
Chapter 11 The Reproduction of Cells
• Cell division functions in reproduction, growth, and
repair~relationship of structure to function/regulation
• Bacteria reproduce by binary fission~regulation
• The genome of a eukaryotic cell is organized into multiple
chromosomes~regulation/relationship of structure to function
• Mitosis alternates with interphase in the cell cycle~regulation
• The mitotic spindle distributes chromosomes to daughter
cells~regulation
• Cytokinesis divides the cytoplasm~regulation
• External and internal cues control cell division~regulation
• Cyclical changes in regulatory proteins function as a mitotic
clock~regulation
• Cancer cells escape from the controls on cell division~regulation
Chapter 12 Meiosis and Sexual Life Cycles
• Offspring acquire genes from parents by inheriting
chromosomes~regulation
• Like begets like, more or less: a comparison of asexual and sexual
reproduction
• Fertilization and meiosis alternate in sexual life cycles~regulation
• Meiosis reduces chromosome number from diploid to
haploid~regulation
• Sexual life cycles produce genetic variation among
offspring~evolution/continuity and change
• Evolutionary adaptation depends on a population’s genetic
variation~evolution/continuity and change
LABS
• AP Lab 1
• Surface Area to Volume Ratio Lab (using agar cubes from Ward’s
Scientific)
• AP Lab 3 Mitosis and Meiosis
8
UNIT III Cellular Energetics
Reading + Topics
(14 days)
Chapter 9 Cellular Respiration: Harvesting Chemical Energy
• Cellular respiration and fermentation are catabolic pathways
• Cells must recycle the ATP they use for work
• Redox reactions release energy when electrons move closer to
electronegative atoms
• Electrons “fall” from organic molecules to oxygen during cellular
respiration
• The “fall” of electrons during respiration is stepwise, via NAD+ and
an electron transport chain
• Respiration is a cumulative function of glycolysis, the Krebs cycle,
and electron transport
• Glycolysis harvests chemical energy by oxidizing glucose to
pyruvate~energy transfer
• The Krebs cycle completes the energy-yielding oxidation of organic
molecules~energy transfer
• The inner mitochondrial membrane couples electron transport to
ATP synthesis
• Cellular respiration generates many ATP molecules for each sugar
molecule it oxidizes~energy transfer
• Fermentation enables some cells to produce ATP without the help
of oxygen
• Glycolysis and the Krebs cycle connect to many other metabolic
pathways
• Feedback mechanisms control cellular respiration~regulation
Chapter 10 Photosynthesis
• Plants and other autotrophs are the producers of the
biosphere~energy transfer/interdependence in nature
• Chloroplasts are the sites of photosynthesis in plants
• Evidence that chloroplasts split water molecules enabled
researchers to track atoms through photosynthesis: science as a
process
• The light reactions and the Calvin cycle cooperate in transforming
light to the chemical energy of food~energy transfer
• The light reactions convert solar energy to the chemical energy of
ATP and NADPH~energy transfer
9
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LABS
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The Calvin cycle uses ATP and NADPH to convert CO2 to sugar
Alternative mechanisms of carbon fixation have evolved in hot, arid
climates~evolution/regulation
Photosynthesis is the biosphere’s metabolic
foundation~interdependence in nature
AP Lab 5 Cell Respiration
Respirometer Lab with CBLs
Elodea Lab
Root Beer Fermentation Lab
AP Lab 4 Plant Pigments and Photosynthesis
TOPIC II
UNIT IV Heredity (14 days)
Reading + Topics
Chapter 13 Mendel and the Gene Idea
• Mendel brought an experimental and quantitative approach to
genetics: science as a process
• According to the law of segregation, the two alleles for a character
are packaged into separate gametes~regulation
• According to the law of independent assortment, each pair of
alleles segregates into gametes independently~regulation
• Mendelian inheritance reflects rules of probability
• Mendel discovered the particulate behavior of genes~science as a
process
• The relationship between genotype and phenotype is rarely simple
• Pedigree analysis reveals Mendelian patterns in human inheritance
• Many human disorders follow Mendelian patterns of inheritance
• Technology is providing new tools for genetic testing and
counseling~science, technology and society
Chapter 14 The Chromosomal Basis of Inheritance
• Mendelian inheritance has its physical basis in the behavior of
chromosomes during sexual life cycles~regulation
• Morgan traced a gene to a specific chromosome: science as a
process
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LABS
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Linked genes tend to be inherited together because they are
located on the same chromosome~regulation
Independent assortment of chromosomes and crossing over cause
genetic recombination~evolution
Geneticists can use recombination data to map a chromosome’s
genetic loci~science as a process
The chromosomal basis of sex produces unique patterns of
inheritance
Alterations of chromosome number or structure cause some
genetic disorders~regulation
The phenotypic effects of some genes depend on whether they
were inherited from the mother or the father~regulation
Extranuclear genes exhibit a non-Mendelian pattern of inheritance
Investigation #4 How are laws of probability applied to genetics?
Investigation #6 Who gets the money?
Investigation #5 Pedigrees
Investigation #8 Inheritance in Zea mays (corn)
Investigation #9 Heredity and environment
Traits and fates Karyotyping lab (NSF)
Beaker Babies Lab (Tufts University)
Gene mapping lab
Genetic disorder research project
Numerous Punnett squares
AP Lab 7 Genetics of Organisms
Wisconsin Fast Plants Lab
UNIT V Molecular Genetics (16 days)
Reading + Topics
Chapter 15
• The search for the genetic material led to DNA: science as a
process
• Watson and Crick discovered the double helix by building models to
conform to X-ray data: science as a process
• During DNA replication, base pairing enables existing DNA strands
to serve as templates for new complementary strands~regulation
• A team of enzymes and other proteins functions in DNA
replication~regulation
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Enzymes proofread DNA during its replication and repair damage to
existing DNA~regulation
Chapter 16 From Gene to Protein
• The study of metabolic defects provided evidence that genes
specify proteins: science as a process
• Transcription and translation are the two main steps from gene to
protein~regulation
• In the genetic, a particular triplet of nucleotides specifies a certain
amino acid~regulation
• Transcription is the DNA-directed synthesis of RNA~regulation
• Translation is the RNA-directed synthesis of a
polypeptide~regulation
• Some polypeptides have signal sequences that target them to
specific destinations in the cell~regulation
• Comparing protein synthesis in prokaryotes and eukaryotes
• Eukaryotic cells modify RNA after transcription~evolution/regulation
• A point mutation can affect the function of a
protein~evolution/structure relates to function
• What is a gene?
Chapter 17 Microbial Models: The Genetics of Viruses and Bacteria
• Researchers discovered viruses by studying a plant disease: science
as a process
• Most viruses consist of a genome enclosed in a protein shell
• Viruses can only reproduce within a host cell~regulation
• Phages exhibit two reproductive cycles: the lytic and lysogenic
cycles~regulation
• Animal viruses are diverse in their modes of infection and
mechanisms of replication~regulation
• Plant viruses are serious agricultural pests~science, technology and
society
• Viroids and prions are infectious agents even simpler than viruses
• Viruses may have evolved form other mobile genetic
elements~evolution
• The short generation span of bacteria facilitates their evolutionary
adaptation to changing environments~evolution
• Genetic recombination and transposition produce new bacterial
strains~evolution/continuity and change
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The control of gene expression enables individual bacteria to adjust
their metabolism to environmental change~regulation/continuity
and change
Chapter 18 Genome Organization and Expression in Eukaryotes
• Each cell of a multicellular eukaryote expresses only a small fraction
of its genome~regulation
• The structural organization of chromatin sets coarse controls on
gene expression~regulation
• Noncoding sequences and gene duplications account for much of a
eukaryotic genome~regulation/relationship of structure to function
• The control of gene expression can occur at any step in the
pathway from gene to functional protein~regulation
• Chemical signals that help control gene expression include
hormones~regulation
• Chemical modification or relocation of DNA within a genome can
alter gene expression~evolution/relationship of structure to
function
• Cancer can result from the abnormal expression of genes that
regulate cell growth and division~regulation
Chapter 19 DNA Technology
• DNA technology makes it possible to clone genes for basic research
and commercial applications~science, technology and society
• The toolkit for DNA technology includes restriction enzymes, DNA
vectors, and host organisms~science, technology and society
• Recombinant DNA technology provides a means to transplant genes
from one species into the genome of another~science, technology
and society
• Additional methods for analyzing and cloning nucleotide sequences
increase the power of DNA technology~science, technology and
society
• DNA technology is catalyzing progress in many fields of
biology~science, technology and society
• The Human Genome Project is an enormous collaborative effort to
map and sequence DNA~science, technology and society
• DNA technology is reshaping the medical and pharmaceutical
industries~science, technology and society
• DNA technology offers forensic, environmental, and agricultural
applications~science, technology and society
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LABS
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DNA technology raises important safety and ethical
questions~science, technology and society
Viral Spread Lab
Investigation #12 DNA Structure
Investigation #13 DNA Extraction from Cells
Investigation #14 Simulating Protein Synthesis
Investigation #15 Hidden Message
Investigation #10 Mosaic Cats
Investigation #18 Tools of the Genetic Engineer
Investigation #24 DNA Profiling
Investigation #25 Detection of Genetic Disease using RFLP Analysis
AP Lab 6 Molecular Biology
UNIT VI Mechanisms
Reading + Topics
of Evolution
Chapter 20 Descent with Modification: A Darwinian View of Life
• Western culture resisted evolutionary views of life~science,
technology and society
• Theories of geological gradualism helped clear the path for
evolutionary biologists~science as a process
• Lamarck placed fossils in an evolutionary context~science as a
process
• Field research helped Darwin frame his view of life: science as a
process
• The Origin of Species developed two main points: the occurrence of
evolution and natural selection as its mechanism
• Evidence from many fields of biology validates the evolutionary
view of life
• What is theoretical about the Darwinian view of life?
Chapter 21 The Evolution of Populations
• The modern evolutionary synthesis integrated Darwinism and
Mendelism: science as a process
• A population has a genetic structure defined by its gene pool’s
allele and genotype frequencies
• The Hardy-Weinberg theorem describes a nonevolving population
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Microevolution is a generation-to-generation change in a
population’s allele or genotype frequencies
Genetic drift can cause evolution via chance fluctuation in a small
population’s gene pool
Gene flow can cause evolution by transferring alleles between
populations
Mutations can cause evolution by substituting one allele for another
in a gene pool~evolution/continuity and change
Nonrandom mating can cause evolution by shifting the frequencies
of genotypes in a gene pool~evolution/continuity and change
Natural selection can cause evolution via differential reproductive
success among varying members of a population
Genetic variation is the substrate for natural
selection~evolution/continuity and change
Natural selection is the mechanism of adaptive evolution
Does evolution fashion perfect organisms?
Chapter 24 Early Earth and the Origin of Life
• Life on Earth originated between 3.5 and 4.0 billion years ago
• The first cells may have originated by chemical evolution on a
young Earth
• Abiotic synthesis of organic monomers is a testable hypothesis:
science as a process
• Laboratory simulations of early Earth conditions have produced
organic polymers
• Protobionts can form by self-assembly
• RNA was probably the first genetic material
• The origin of hereditary information made Darwinian evolution
possible
• Debate about the origin of life abounds
• Arranging the diversity of life into kingdoms is a work in progress
LABS
• Investigation #16 Using Comparative Genetics to Examine
Evolutionary Relationships
• Gene Frequency Lab using M &Ms Candy
• AP Lab 8 Population Genetics and Evolution
15
TOPIC III
UNIT VII Diversity of Organisms
Reading + Topics
Chapter 22 The Origin of Species
• The biological species concept emphasizes reproductive isolation
• Reproductive barriers separate species
• Geographical isolation can lead to the origin of species: allopatric
speciation
• A new species can originate in the geographical midst of the parent
species: sympatric speciation
• Population genetics can account for speciation
• The theory of punctuated equilibrium has stimulated research on
the tempo of speciation
Chapter 23 Tracing Phylogeny: Macroevolution, the Fossil
Record, and Systematics
• The fossil record documents macroevolution
• Paleontologists use a variety of methods to date fossils
• What are the major questions about macroevolution?
• Some evolutionary novelties are modified versions of older
structures
• Genes that control development play a major role in evolutionary
novelty
• Recognizing trends in the fossil record does not mean that
macroevolution is goal-oriented
• Macroevolution has a biogeographical basis in continental drift
• The history of life is punctuated by mass extinctions followed by
adaptive radiations of the survivors
• Systematics connects biological diversity to phylogeny
• Molecular biology provides powerful new tools for modern
systematics~science, technology and society
• Cladistics highlights the phylogenetic significance of systematics
• Is a new evolutionary synthesis necessary?
16
Chapter 25 Prokaryotes and the Origins of Metabolic Diversity
• They’re (almost) everywhere!
• Archaea and Bacteria are the two main branches of prokaryotic
evolution
• The success of prokaryotic life is based on diverse adaptations of
form and function
• All major types of nutrition and metabolism evolved among
prokaryotes
• The evolution of prokaryotic metabolism was both cause and effect
of changing environments of Earth
• Molecular systematics is leading to a phylogenetic classification of
prokaryotes
• Prokaryotes continue to have an enormous ecological impact
Chapter 26 The Origins of Eukaryotic Diversity
• Eukaryotes originated by symbiosis among prokaryotes
• Archezoans provide clues to the early evolution of eukaryotes
• The diversity of protists represents “experiments” in the evolution
of eukaryotic organization
• Protistan taxonomy is in a state of flux
• Diverse modes of locomotion and feeding evolved among protozoa
• Funguslike protists have morphological adaptations and life cycles
that enhance their ecological role as decomposers
• Eukaryotic algae are key producers in most aquatic ecosystems
• Systematists continue to refine their hypotheses about eukaryotic
phylogeny
• Multicellularity originated independently many times
Chapter 27 Plants and the Colonization of Land
• Structural and reproductive adaptations made colonization of land
possible: an overview of plant evolution
• Plants probably evolved from green algae called charophytes
• Bryophytes are embryophytes that generally lack vascular tissue
and require environmental water to reproduce~relationship of
structure to function
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The origin of vascular tissue was an evolutionary breakthrough in
the colonization of land
Ferns and other seedless plants dominated the Carboniferous “coal
forests”
Reproductive adaptations catalyzed the success of the seed
plants~relationship of structure to function
Gymnosperms began to dominate landscapes as climates became
drier at the end of the Paleozoic era~relationship of structure to
function
The evolution of flowers and fruits contributed to the radiation of
angiosperms
Plant diversity is a nonrenewable resource~continuity and
change/interdependence in nature
Chapter 28 Fungi
• Structural and life history adaptations equip fungi for an absorptive
mode of nutrition~continuity and change/interdependence in nature
• The three major divisions of fungi differ in details of reproduction
• Molds, yeasts, lichens, and mycorrhizae represent unique lifestyles
that evolved independently in all fungal divisions
• Fungi have a tremendous ecological impact~interdependence in
nature
• Fungi and animals probably evolved from a common protistan
ancestor~evolution
Chapter 29 Invertebrates and the Origin of Animal Diversity
• What is an animal?
• Comparative anatomy and embryology provide clues to animal
phylogeny~evolution
• Sponges are sessile animals lacking true tissues
• Cnidarians with ctenophores are radiate, diploblastic animals with
gastrovascular cavities
• Flatworms and other acoelomates are bilateral, triploblastic animals
lacking body cavities
• Rotifers, nematodes, and other pseudocoelomates have complete
digestive tracts and blood vascular systems
• Mollusks and annelids are among the major variations on the
protostome body plan
• The protostome phylum Arthopoda is the most successful group of
animals ever to live
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The deuterstome lineage includes echinoderms and chordates
The Cambrian explosion produced all the major animal body plans
Chapter 30 The Vertebrate Genealogy
• Vertebrates belong to the phylum Chordata
• Invertebrate chordates provide clues to the origin of vertebrates
• The evolution vertebrate characteristics is associated with
increased size and activity
• Vertebrate diversity and phylogeny
• Agnathans are jawless vertebrates
• Placoderms were armored fishes with jaws and paired fins
• Sharks and their relatives have adaptations for powerful swimming
• Bony fishes are the most abundant and diverse vertebrates
• Amphibians are the oldest class of tetrapods
• The evolution of the amniotic egg expanded the success of
vertebrates on land
• A reptilian heritage is evident in all amniotes
• Birds began as flying reptiles
• Mammals diversified extensively in the wake of the Cretaceous
extinctions
• Primate evolution provides a context for understanding human
origins
• Humanity one very young twig on the vertebrate tree
Labs
• Streaking agar plate and use of inoculating loop
• Bacteria in Milk (Flinn Scientific)
UNIT VIII Structure
Reading + Topics
and Function of Plants and Animals (57 days)
Chapter 31 Plant Structure and Growth
• Plant biology reflects the major themes in the study of life
• A plant’s root and shoot systems are evolutionary adaptations to
living on land
• The major types of plant cells are organized into three major tissue
systems
• Meristems generate cells for new organs throughout the lifetime of
a plant
• Apical meristems extend roots and shoots
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Lateral meristems add girth to stems and roots
Chapter 32 Transport in Plants
• The traffic of water and solutes occurs on cellular, organ and
whole-plant levels
• Roots absorb water and minerals from soil
• The ascent of xylem sap depends mainly on transpiration and the
physical properties of water
• Guard cells mediate the transpiration-photosynthesis compromise
• A bulk-flow mechanism translocates phloem sap from sugar sources
to sugar sinks
Chapter 33 Plant Nutrition
• Plants require at least seventeen essential nutrients
• The symptoms of a mineral deficiency depend on the function and
mobility of the element
• Soil characteristics are key environmental factors in terrestrial
ecosystems
• Soil conservation is one step toward sustainable
agriculture~science, technology and society
• The metabolism of soil bacteria makes nitrogen available to plants
• Improving the protein yield of crops is a major goal of agricultural
research~science, technology and society, science as a process
• Predation and symbiosis are evolutionary adaptations that enhance
plant nutrition~interdependence in nature
Chapter 34 Plant Reproduction and Development
• Sporophyte and gametophyte generations alternate in the life
cycles of plants
• Male and female gametophytes develop within anthers and ovaries,
respectively
• Pollination brings female and male gametophytes together
• The ovule develops into a seed containing a sporophyte embryo
and a supply of nutrients
• The ovary develops into a fruit adapted for seed dispersal
• Evolutionary adaptations in the process of germination increase the
probability that seedlings will survive
• Many plants can clone themselves by asexual reproduction
• Vegetative reproduction of plants is common in agriculture
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Sexual and asexual reproduction re complementary in the life
histories of many plants
Growth, morphogenesis, and differentiation produce the plant body
The cytoskeleton guides the geometry of cell division and
expansion
Cellular differentiation depends on the control of gene expression
Mechanisms of pattern formation determine the location and tissue
organization of plant organs
Chapter 35 Control Systems in Plants
• Research on how plants grow toward light led to the discovery of
plant hormones: science as a process
• Plant hormones help coordinate growth, development, and
responses to environmental stimuli~regulation
• Tropisms orient the growth of plant organs toward or away from
stimuli~regulation
• Turgor movements are relatively rapid, reversible plant responses
• Biological clocks control circadian rhythms in plants and other
eukaryotes~regulation
• Photoperiodism synchronizes many plant responses to changes of
season~regulation
• Phytochrome functions as a photoreceptor in many plant responses
to light and photoperiod~regulation
• Control systems enable plants to cope with environmental
stress~regulation/interdependence in nature
• Signal-transduction pathways mediate the responses of plant cells
to environmental and hormonal stimuli~regulation/interdependence
in nature
Chapter 36 An Introduction to Animal Structure and Function
• The functions of animal tissues and organs are correlated with their
structures~relationship of structure to function
• Bioenergetics is fundamental to all animal functions~energy transfer
• An animal’s size and shape affect its interactions with the external
environment~interdependence in nature/relationship of structure to
function
• Homeostatic mechanisms regulate an animal’s internal
environment~regulation
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Chapter 37 Animal Nutrition
• Diets and feeding mechanisms vary extensively among animals
• Ingestion, digestion, absorption, and elimination are the four main
stages of food processing~energy transfer/relationship of structure
to function
• Digestion occurs in food vacuoles, gastrovascular cavities, and
alimentary canals~ energy transfer/relationship of structure to
function
• A tour of the mammalian digestive system
• Vertebrate digestive systems exhibit many evolutionary
adaptations associated with diet
• An adequate diet provides fuel, carbon skeletons for biosynthesis,
and essential nutrients~energy transfer
Chapter 38 Circulation and Gas Exchange
• Transport systems functionally connect body cells with the organs
of exchange~relationship of structure to function
• Most invertebrates have a gastrovascular cavity or a circulatory
system for internal transport
• Diverse adaptations of a cardiovascular system have evolved in
vertebrates~evolution/relationship of structure to function
• Rhythmic pumping of the human heart drives blood through
pulmonary and systemic circuits
• The lymphatic system returns fluid to the blood and aids in body
defense
• Blood is a connective tissue with cells suspended in plasma
• Cardiovascular diseases are the leading cause of death in the United
States and many other developed nations~science, technology and
society
• Gas exchange supplies oxygen for cellular respiration and disposes
of carbon dioxide~relationship of structure to function
• Gills are respiratory adaptations of most aquatic animals~evolution
• Tracheae are respiratory adaptations of insects~evolution
• Lungs are the respiratory adaptation of most terrestrial
vertebrates~ evolution
Chapter 39 The Body’s Defenses
• Nonspecific mechanisms provide general barriers to infection
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The immune system defends the body against specific
invaders~regulation
Clonal selection of lymphocytes is the cellular basis for
immunological specificity and diversity
Memory cells function in secondary immune
responses~regulation/relationship of structure to function
Molecular markers on cell surfaces function in self/nonself
recognition~regulation/relationship of structure to function
In the humoral response, B cells defend against pathogens in body
fluids by generating specific antibodies~regulation/relationship of
structure to function
In the cell-mediated response, T cells defend against intracellular
pathogens~regulation/relationship of structure to function
Complement proteins participate in both nonspecific and specific
defenses
The immune system’s capacity to distinguish self for nonself is
critical in blood transfusions and transplantation
Abnormal immune function leads to disease states~science,
technology and society
Invertebrates exhibit a rudimentary immune system
Chapter 40 Controlling the Internal Environment
• Homeostatic mechanisms protect an animal’s internal environment
from harmful fluctuations~regulation
• Cells require a balance between water uptake and loss
• Osmoregulation depends on transport
epithelia~regulation/relationship of structure to function
• Tubular systems function in osmoregulation and excretion in many
invertebrates
• The kidneys of most vertebrates are compact organs with many
excretory tubules
• The kidney’s transport epithelia regulate the composition of
blood~regulation/relationship of structure to function
• The water-conserving ability of the mammalian kidney is a key
terrestrial adaptation~evolution
• Diverse adaptations of the vertebrate kidney have evolved in
different habitats~evolution
• An animal’s nitrogenous wastes are correlated with its phylogeny
and habitat
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Thermoregulation maintains body temperature within a range
conducive to metabolism~regulation
Ectotherms derive body heat mainly from their surroundings and
endotherms derive it mainly from metabolism
Thermoregulation involves physiological and behavior
adjustments~regulation
Comparative physiology reveals diverse mechanisms of
thermoregulation~evolution
Regulatory systems interact in the maintenance of
homeostasis~regulation
Chapter 41 Chemical Signals in Animals
• A variety of chemical signals coordinates body functions~regulation
• Hormone binding to specific receptors triggers signaling
mechanisms at the cellular level~regulation
• Many chemical signals are relayed and amplified by second
messengers and protein kinases
• Invertebrate control systems often integrate endocrine and nervous
system functions
• The hypothalamus and pituitary integrate many functions of the
vertebrate endocrine system
• The vertebrate endocrine system coordinates homeostasis and
regulates growth, development, and reproduction~regulation
• The endocrine system and the nervous system are structurally,
chemically, and functionally related~regulation/interdependence in
nature
Chapter 42 Animal Reproduction
• Both asexual and sexual reproduction occur in the animal kingdom
• In sexual reproduction, gametes unite in the external environment
or within the female
• Diverse reproductive systems have evolved in the animal kingdom
• Human reproduction involves intricate anatomy and complex
behavior
• Spermatogenesis and oogenesis both involve meiosis but differ in
three significant ways
• A complex interplay of hormones regulates reproduction~regulation
• Embryonic and fetal development occur during pregnancy in
humans and other placental mammals
• Contraception prevents pregnancy
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New technologies offer help for reproductive problems~science,
technology and society
Chapter 43 Animal Development
• From egg to organism, an animal’s form develops gradually: the
concept of epigenesis~regulation
• Embryonic development involves cell division, differentiation, and
morphogenesis~regulation
• Fertilization activates the egg and brings together the nuclei of
sperm and egg
• Cleavage partitions the zygote into many smaller cells~regulation
• Gastrulation rearranges the blastula top form a three-layered
embryo with a primitive gut~regulation
• Organogenesis forms the organs of the animal body from the three
embryonic germ layer~regulation
• Amniote embryos develop in a fluid-filled sac within a shell or uterus
• The developmental fate of cells depends on cytoplasmic
environment, location, and cell-cell interactions~interdependence in
nature
• Pattern formation in Drosophila is controlled by a hierarchy of gene
activations~regulation
• Comparisons of genes that control development reveal homology in
animals as diverse as flies and mammals~evolution
Chapter 44 Nervous Systems
• Nervous systems perform the three overlapping functions of
sensory output, integration, and motor
output~regulation/relationship of structure to function
• The nervous system is composed of neurons and supporting cells
• Impulses are action potentials, electrical signals propagated along
neuronal membranes
• Chemical or electrical communication between cells occurs at
synapses~regulation
• Invertebrate nervous systems are highly diverse
• The vertebrae nervous system is a hierarchy of structural and
functional complexity
• The human brain is a major research frontier~science, technology
and society
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Chapter 45 Sensory and Motor Mechanisms
• Sensory receptors detect changes in the external and internal
environment~regulation/relationship of structure to function
• Photoreceptors contain light-absorbing visual pigments~
regulation/relationship of structure to function
• Hearing and balance are related in most animals~
regulation/relationship of structure to function
• The interacting senses of taste and smell enable animals to detect
many different chemicals~ regulation/relationship of structure to
function/interdependence in nature
• Movement is a hallmark of animals
• Muscles move skeletal parts by contracting~relationship of
structure to function
LABS
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AP Lab 9 Transpiration
AP Lab 10 Physiology of the Circulatory System
AP Lab 11 Animal Behavior
Fast Food Lab
Donner Party Lab
Anorexia Lab “Madeline” (BSCS)
Fetal Pig Dissection
UNIT IX ECOLOGY (18 days)
Reading + Topics
Chapter 46 An Introduction to Ecology: Distribution and
Adaptations of Organisms
• Ecology is the scientific study of the interactions between
organisms and their environments~interdependence in nature
• Basic ecology provides a scientific context for evaluating
environmental issues~science, technology and society
• Ecological research ranges from the adaptations of organisms to
the dynamics of ecosystems~interdependence in nature
• Climate and other abiotic factors are important determinants of the
biosphere’s distribution of organisms~interdependence in nature
• The costs and benefits of homeostasis affect an organism’s
responses to environmental variation~interdependence in
nature/continuity and change
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The response mechanisms of organisms are related to
environmental grain and the time scale of environmental
variation~interdependence in nature
The geographical distribution of terrestrial biomes is based mainly
on regional variations in climate
Aquatic ecosystems, consisting of freshwater and marine biomes,
occupy the largest part of the biosphere
Chapter 47 Population Ecology
• Two important characteristics of any population are its density and
the spacing of individuals~interdependence in nature/continuity and
change
• Demography is the study of factors that affect birth and death
rates in a population~interdependence in nature/continuity and
change
• The traits that affect an organism’s schedule of reproduction and
death make up its life history~regulation
• A mathematical model for exponential growth describes an idealized
population in an unlimited environment
• A logistic model of population growth incorporates the concept of
carrying capacity
• Both density-dependent and density-independent factors can affect
population growth~interdependence in nature /continuity and
change
• The human population has been growing exponentially for centuries,
but will not be able to do so indefinitely~interdependence in
nature/continuity and change/science, technology and society
Chapter 48 Community Ecology
• The interactive and individualistic hypotheses pose alternative
explanations of community structure: science as a process
• Community interactions can provide strong selection factors in
evolution~interdependence in nature /continuity and
change/evolution
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Interspecific interactions may have positive, negative, or neutral
effects on a population’s density~interdependence in nature
/continuity and change/evolution
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Predation and parasitism are +/- interactions~interdependence in
nature
Interspecific competitions are -/- interactions~interdependence in
nature
Commensalisms and mutualism are +/0 and +/+ interactions,
respectively~interdependence in nature
A community’s structure is defined by the activities and abundance
of its diverse organisms~interdependence in nature
The factors that structure communities include competition,
predation, and environmental patchiness~interdependence in nature
Succession is the sequence of changes in a community after a
disturbance~interdependence in nature/evolution
Biogeography complements community ecology in the analysis of
species distribution
Lessons from community ecology and biogeography can help
preserve biodiversity~science, technology and society
Chapter 50 Behavior
• Behavior is what an animal does and how it does it~
interdependence in nature
• Behavior ecology emphasizes evolutionary hypotheses: science as a
process
• A behavior has both an ultimate and a proximate cause~
interdependence in nature
• Certain stimuli trigger innate behaviors called fixed action patterns~
interdependence in nature
• Learning is experience-based modification of behavior~
interdependence in nature
• Rhythmic behaviors synchronize an animal’s activities with daily and
seasonal changes in the environment~interdependence in nature
• Environmental cues guide animal movement~interdependence in
nature
• Behavioral ecologists are using cost/benefit analysis to study
foraging behavior~interdependence in nature
• Sociobiology places social behavior in an evolutionary context~
interdependence in nature/evolution
• Competitive social behaviors often represent contests for
resources~ interdependence in nature
• Mating behavior relates directly to an animal’s fitness~
interdependence in nature/regulation
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Social interactions depend on diverse modes of communication~
interdependence in nature
The concept of inclusive fitness can account for most altruistic
behavior~ interdependence in nature
Human sociobiology connects biology to the humanities and social
sciences
LABS
• AP Lab 12 DO and Aquatic Primary Productivity
• Various labs from Water Quality with CBLs (Vernier)
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