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HYMAN HARTMAN Hyman Hartman was born in Montreal, Quebec, Canada. He received his B.Sc with honors In Biochemistry from McGill University (1957) and his PhD in Biochemistry from Columbia University (1964). He began his studies on the Origin of Life by publishing two pioneering papers in 1974 on the Evolution of the Genetic Code and the Origin and Evolution of Metabolism. These papers were based on the Clay theory for the Origin of Life. He edited a book with Graham Cairns-Smith entitled Clay Minerals and the Origin of Life (1987). He was on the Grant Board for NASA Exobiology Division and he was a co-editor with Jim Lawless and Phil Morrison on the book Search for the Universal Ancestors published by NASA. He and Temple Smith (Boston University) have been studying the Bioinformatics of the Ribosomal Proteins and the AminoacyltRNA Synthetases. These studies have allowed them to reconstruct the Origin and Evolution of the Translational Apparatus and the Origin and Evolution of the Genetic Code. He is also active with a group in the University of Kentucky and McGill University studying the De Novo synthesis of Clay as catalyzed by Amino acids and Dicarboxylic acids. The Origin of the Genetic Code and Metabolism: From the Eukaryotic Cell to the Carbonaceous Chondrites This lecture will be a journey starting with the Eukaryotic cell and then descending through the evolution of the Eukaryotic Cell to the Origin and Evolution of the Translational Apparatus and the Genetic Code. Then proceeding to the bacterial endosymbionts (mitochondria and choloroplasts) of the Eukaryotic Cell we are able reconstruct from them the evolution of metabolism (Biochemistry ) including Photosynthesis and then we continue to the Clays and Amino acids on Carbonaceous Chondrites (4.5 Billion years old). The experiments that will be discussed will be on the in vitro synthesis of Clays and the role that amino acids and dicarboxylic acids play in catalyzing the synthesis of the Clays themselves. These experiments are models for what happened on the Carbonaceous Chondrites 4.5 Billion years ago. Website: http://segovia.mit.edu/~hartman/