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Transcript
Lorne Infection and Immunity Conference 2017 Preliminary Program – Subject to change Mantra Lorne, 15-17 February 2017 Wednesday, February 15, 2017 12:00-13:00 Registration 13:00-13:10 Welcome + opening remarks 13:10-15:00 Session 1: Host - Pathogen Interactions 13.10-13.40 Thierry Soldati, University of Geneva Infecting Amoebae with Mycobacteria to Study Conserved Mechanisms of Cellular Innate Defences 13.40-14.00 Cynthia Whitchurch, University of Technology, Sydney Roles of bacterial morphotype plasticity in infection Wai-Hong Tham, Walter and Eliza Hall Institute 14.00-14.15 14.15-14.30 Malaria parasite invasion, versatile structural scaffolds and alternate erythrocyte receptors Amit Singhal, Singapore Immunology Network Reprograming host immune-metabolic circuits for restricting TB Matthew J Sullivan, Griffith University 14.30-14:45 14.45-15.00 The Streptococcus agalactiae virulence regulator CovR affects the pathogenesis of urinary tract infection Thomas Naderer, Monash University Targeting host cell death factors in infections 15:00-15:30 Afternoon tea 15:30-17:30 Session 2: Regulation of immunity 15.30-16.00 Bali Pulendran, Emory Vaccine Centre Systems Vaccinology: enabling rational vaccine design with systems biological approaches. 16.00-16.20 David Lynn, South Australian Health and Medical Research Institute Interplay between the microbiome, vaccines and the immune system Sam Forster, Wellcome Trust Sanger Institute 16.20-16:35 16.35-16.50 Culturing 'unculturable' human gastrointestinal microbiota provides phenotypic insights for bacteriotherapy design Ben Wade, Deakin University MicroRNA; a telltale sign of stress? 16:50-17:30 ~12x3min student talks 17.30-18.30 Break 18:30-20:00 Dinner – Mantra Lorne 20:00-21:30 Poster Session I Thursday, February 16, 2017 7:00-8:30 Breakfast 7:15-8:15 Jomar Life Research Breakfast Workshop 8:30-10:05 Session 3: Pathogenesis and Prevention of Viral Infections 8.30-9:00 George Gao, Chinese Academy of Sciences TBC 9:00-9.20 Katherine Kedzierska, University of Melbourne Immunity to the newly emerged A/H7N9 influenza virus 9.20-9.35 Stephen Rawlinson, University of Melbourne Hendra virus matrix protein localises to sub-nucleolar puncta, interacts with treacle and inhibits rRNA production 9.35-9:50 David Thomas, Monash University Nuclear trafficking of Venezuelan Equine Encephalitis Virus capsid protein as an antiviral target 9:50-10:05 Natalie Borg, Monash University Characterisation of Hendra virus V protein interactions with human nuclear transport receptors reveals opportunities to target Hendra virus infection 10:05-10:35 Morning tea 10:35-12:10 Session 4: Innate Immunity to Infection 10.35-11.05 Sonja Best, BNIH Rocky Mountain Laboratories, NIAID/NIH Move over retroviruses: restriction of flavivirus replication by human TRIM5a 11.05-11.25 Sammy Bedoui, University of Melbourne The role of microbiota in regulating CD8+ T cell memory 11:25-11:40 11.40-11.55 11.55-12.10 Si Ming Man, Australian National University Interferon-inducible proteins are essential for the activation of the inflammasomes Anthony Sadler, Hudson Institute and Monash Medical Centre MDA5 limits rotavirus infection but promotes cell death and inflammation in the pancreas Amelia Soderholm, University of Queensland Interaction of Group A Streptococcus with innate immune pathways 12:10-13:20 Lunch 12.15-13.15 Early Career Researcher Lunch 12.15-13.15 AVS Annual General Meeting 13:20-14:40 Session 5: Inflammation and Infectious Diseases 13.20-13.50 Caroline Demangel, Institut Pasteur Host immunomodulation by Mycobacterium ulcerans, the causative agent of Bairnsdale ulcer 13.50-14.10 Connie Wong, Monash University Translocation and dissemination of commensal bacteria in post-stroke infection 14.10-14.25 Bin Wei, Chinese Academy of Sciences STK4 regulates TLR pathways and protects against chronic inflammation–related hepatocellular carcinoma Nollaig Bourke, Hudson Institute of Medical Research 14.25-14.40 Characterising the novel regulation and function of interferon epsilon in the female reproductive tract 14.40-15:10 Afternoon tea 15:10-16:20 Session 6: ECR Session 15.10-15.25 VIIN Career Development Award Winner: Marcel Doerflinger, Walter and Eliza Hall Institute Utilizing in vitro CRISPR/Cas9 screening platforms for functional genomics to decipher host cell death mechanisms in chronic and acute infectious diseases 15.25-15.40 VIIN Career Development Award Winner: Michaela Finsterbusch, Monash University Monocytes contribute to neutrophil-dependent kidney injury in acute glomerulonephritis 15.40-16.20 ~12x3min ECR talks 16:20-17:00 Break 17:00-18:30 Session 7: Plenary 17:00-17:15 VIIN Young Investigator Award Winner: Charlotte Nejad, Hudson Institute of Medical Research Type-I Interferon dependent degradation of microRNA isoforms in mouse macrophages 17.15-17.30 VIIN Young Investigator Award Winner: Rhys Grinter, Monash University The structural basis of bacterial iron piracy from host ferredoxin 17.30-18.30 Plenary: Dominique Soldati-Favre, Geneva Medical School Apicomplexan aspartyl proteases play fundamental roles in establishment of parasitism 18:30-20:00 Dinner – Lorne Hotel 20:00-21:30 Poster Session II Friday, February 17, 2017 7:00-8:30 Breakfast and check out 8:30-10:20 Session 8: Adaptive Immunity to Infection 8.30-9.00 Marion Pepper, University of Washington Understanding Plasmodium-specific B cells 9.00-9.20 David Tscharke, Australian National University A CD8+ T cell-eye view of virus infection 9.20-9.35 9.35-9:50 Julian Vivian, Monash University MHC-I peptides get out of the groove and enable a novel mechanism of HIV-1 escape Susan Christo, University of Melbourne Differential programming shapes tissue-resident memory T cells in distinct environments 9:50-10.05 Simone Park, University of Melbourne Spontaneous formation and protective potential of tumour-specific tissue-resident memory T cells 10:05-10:20 Timothy Wells, University of Queensland Diamantina Institute Paradoxical antibody: The scope and treatment of antibody that exacerbates Gram- negative infections 10:20-10:50 Morning Tea 10:50-12:55 Session 9: Vaccines, Therapeutics and Diagnostics 10.50-11.20 Nancy Haigwood, Oregon Health and Science University The critical role of antibodies in HIV transmission, immunity, and vaccine development 11.20-11.40 Rowena Martin, Australian National University The role of an essential parasite-encoded transporter in the digestion of host cell proteins 11.40-11:55 11.55-12.10 Stephen Kent, University of Melbourne Partial efficacy of a broadly neutralizing antibody against cell-associated SHIV infection Larissa Dirr, Griffith University Challenges in inhibitor design for human parainfluenza virus type-3 - The butterfly effect Cody Allison, Walter and Eliza Hall Institute 12.10-12.25 12:25-12:40 12.40-12.55 The clinical stage SMAC-mimetic, birinapant, specifically sensitises HIV-infected CD4+ T cells to death, reducing viraemia and time-to-rebound in anti-retroviral treated humanised mice Kate Markey, QIMR Berghofer Medical Resarch Institute Towards a rapid molecular test for diagnosis and prediction of blood stream infection Diana Quan, University of Sydney Natural products as novel therapies for tuberculosis 12.55-13.00 Closing remarks 13:00- Depart