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Healthy Soil Cover Crops, Composting & Microbe Propagation Circle of Life Healthy People Healthy Soil Microbes! Healthy Food Healthy Human Gut Microbes! History of the Connections between Healthy Soil, Food grown in it, and Human Health… Why Magnesium is Important, why we have become Deficient, and how you can improve it The Boron Story which is similar to Mg. Why Vitamin D is Important, & Help you Understand How to Deal with it Successfully Finally, Gut Microbes, the New Frontier of Human Health, influenced (Controlled?) by our Diets - Many in the Audience cannot hear the question being asked… - Many questions will be answered later in the talk anyway… - It causes me to run way over my time limit! “Healthy Soil, Healthy Food, Healthy People” has been attributed to J. I. Rodale, viewed by many as the father of the organic farming movement. , PhD 4. J. I. Rodale Father of Organic Movement 1898 – 1971 – 1947, The Rodale Institute “Healthy Soil, Healthy Food, Healthy People” “Prevention”1950 5. Charles Walters, Jr. 1926 – 2009 Sustainable Farming, Acres USA, “The Albrecht Papers” The Farm Unfortunately there has been Resistance, both in Agriculture and Medicine, to Acceptance of these Important Concepts. • In the 1800’s, the availability of pristine farmland in the West provided the opportunity for early settlers to move there after depleting the east coast soil so it no longer produced crops, because of poor unsustainable farming practices. Modern farming practices, especially since World War II, emphasize the use of chemical fertilizers, pesticides and herbicides to maximize yield, ignoring the impact on the quality of the soil and the Nutrient Density of the food produced. Iron in hemoglobin carries Oxygen throughout the body, keeping tissues alive and healthy. Chlorophyll uses sunlight to make sugars, critical for plant growth and health. A portion is excreted through the roots to feed soil biota in exchange for important soil nutrients. Twilight Zone… Sign of corn magnesium deficiency Grass Tetany – Impact on Cow Grazing magnesium deficient grass. The Circle of Life: Healthy Soil, Healthy www.mooregrassfedbeef.com Food, Healthy People ! “ Multiple Local Beef Farmers Cooperative Direct Selling Local Grass Fed Beef Please visit our website to learn more! Magnesium is needed for approximately 300 biochemical reactions in the body. •It • serves a similar # of functions in plants. Helps maintain normal muscle and nerve function Keeps heart rhythm steady Supports a healthy immune system • • Heart health, high BP & vascular disease Diabetes, asthma, cancer Dementia, depression and mental illnesses Osteoporosis Fibromyalgia, PMS Migraine headaches, strokes US Dietary Intake of Magnesium: Moderately Below RDA At or Above RDA Significantly Below RDA Soft drinks, medications, and other factors can often cause inadequate absorption of the Magnesium by their digestive systems resulting progressive total body Magnesium deficiency. . Our agricultural soils have systematically become depleted because of a failure to replace Mg lost from crop harvesting. Today’s diets, eaten by most, contain insufficient Mg Some medications result in either problems absorbing Mg (Acid lowering meds, Soft Drinks), or increase its kidney excretion. (Diuretics) Major Illnesses, Trauma and Surgery all cause sudden super depletions of Mg. Unfortunately, it is not routinely possible to do testing for it since it is ~ 98% inside the cells of our body. After Oxygen, water & basic food, Mg may be the most important element needed by our bodies. More important than Calcium, Potassium or Sodium, & it Regulates all 3 of them! (but so does Boron…) Livestock farmers have been told for many years that Hi-Mg supplements must be supplied to their animals if they want them to be healthy and thrive! Too bad someone forgot to tell most Doctors… In animals, magnesium is essential for muscular and nervous systems. Deficiency causes a wide array of life threatening challenges that are illustrated above. Individuals with Diabetes almost all have low Mg. People with low Mg are much more likely to develop Diabetes. People who routinely consume low Mg containing diets are much more likely to develop Diabetes. How Mg connects with the Insulin Resistance and Diabetes check the link: (from 2009) http://drsircus.com/medicine/magnesium/theinsulin-magnesium-story-2/ •Insulin Resistance leads to Diabetes •Thromboxane •Enhances causes elevated BP and also blood clotting which is a problem with MI’s and Strokes •Americans •Pre-Diabetes •Pre •Suggests •29 >65 years old: 26% are Diabetic (elevated A1C ) Adults > 20 y.o.: 37% Diabetes in Adults >65: 51% vast majority people > 65 are in trouble… Million Americans are now Diabetic •Another 86 Million are Pre-Diabetic •Significantly Reduced risk of Diabetes •Promotes •Improved Weight loss Cardiovascular health is observed •Lowered BP & Decreased Stroke Risk The Foods in a Mediterranean Diet are rich in Magnesium! Eating a magnesium-rich diet is important in fighting against the Metabolic Syndrome according to a new study funded by the National Heart, Lung and Blood Institute (1). Spanish researchers did a prospective study Following the subjects for five years, They found those with the highest average intakes of magnesium (442 mg/day) were at... • 59% reduced risk of Cardiovascular Mortality, a • 37% reduction in Cancer Mortality, and a • 34% reduction in all-cause mortality, • The study authors conclude that: “Dietary magnesium intake was Inversely Associated with Mortality Risk in Mediterranean individuals at High Risk of Heart Disease.” An article published online on April 7, 2008 in the Proceedings of the National Academy of Sciences reported human cells grown in Mg deficient culture undergo accelerated senescence (aging). “The long-term consequence of low Mg in human fibroblast cultures was accelerated cellular aging which may be a mechanism by which chronic low Mg diet could cause or speed up age-related disease.” This same cellular DNA division defect mechanism could also account for the increase of observed malignancies! (Higher risk of Mutations) Giving IV Mg Sulphate within 2 hours of a Stroke resulted in dramatic early recovery in 42% of patients and a good 90 day outcome in 75% of treated patients. High BP is a primary cause of Stroke, but a High Mg diet results in lower BP Mg also causes decreased clumping of Platelets (clots), another cause of Strokes Heart rhythm disturbance (Atrial Fib) increases the risk of Strokes, but Mg significantly reduces the risk of Heart arrhythmias! •Magnesium (& Boron!) is intimately connected to Neurological Disorders due to the critical roles in Neurotransmitter Production, energy production and the integrity of the blood brain barrier. •Mg shortage can cause a Serotonin Deficiency with associated Depression, Suicide and Irrational Violence. •In 2002, The National Institute of Health officially listed Depression as a sign of Mg Deficiency. •Increase Magnesium in your diet (i.e., Mediterranean type Diet) •Mg is actually better absorbed thru skin than from gut. Mg “oil” to skin, &/or Epsom Salt soaks •Mg Gluconate is One of the Best Oral sources (550 mg. available from Walgreens on line, take 2-3 X a day) •Best to do all 3 in my opinion. •Like Magnesium, many soils have become deficient, adversely affecting plants and food that we eat. •Boron is related to activation of Vit. D, so it may be part of the reason so many are deficient! •Boron appears to be directly related to Bone health, osteoporosis, joint cartilage health and arthritis. •Regulates sex hormones so appears tied to higher observed rates of low Testosterone and decreased libido Since 1923 Boron was recognized as an Essential Nutrient for plants. •Boron is the most common deficiency of any trace element in plants. •Boron concentration of food varies widely based on the availability of Boron in the soil. •Foods grown on soils with Low Boron levels will then contain Low Boron levels. •Humans who consume these foods then develop Sub-Optimum Boron Levels also. How does it work for humans? •Boron seems to help regulate the way our body handles other minerals such as Calcium, Magnesium and Phosphorus. •It also seems to increase Estrogen, Androgen, & Vit. D levels in older (post-menopausal) women and healthy men. Documenting Study reported in 2003, but it has not seen much light… •Androgens/Testosterone help maintain Muscle Mass and are involved with Libido. (Has become new common deficiency) •Boron has been shown to be helpful in maintaining healthy Bones and Mental Function. Decreased risk of dementia. Boric acid, a common form of boron, is effectively used to kill yeast that cause vaginal infections. Perhaps toenail fungus too? Common Boron deficiency Health Issues: Arthritis & Degenerative cartilage Osteoporosis - Brittle Bones Memory loss Muscle pain Carpal Tunnel syndrome Receding gums/ Periodontal disease Sex Hormonal deficiency - Loss of libido (Active) Vitamin D deficiency s Link between boron deficiency and osteoarthritis. • Epidemiological studies indicate that in Mauritius and Jamaica, where boron intake is low, the incidence of osteoarthritis is around 50 to 70 percent. •In countries such as the USA, UK and Australia, where boron intake is relatively high, the incidence of osteoarthritis is around 20 percent. (but increasing!) •Studies indicate that Boron concentrations in cartilage of osteoarthritic joints appears to be significantly lower than in normal joints.5 Even though I’ve gotten my vegetable garden, after 21 years, in excellent soil shape I’m still a bit deficient in magnesium and boron, despite working to amend and correct these deficiencies. “Doing the right thing” does not immediately correct decades of farming practices that caused the deficiencies to develop. March 2017 AARP Bulletin How My Interest in Vitamin D came about.. • As a medical student, I developed a presentation for medical students and endocrinology residents related to Bone Metabolism and Calcium, which involved Vitamin D. D3 had just become available. • Work and research with an endocrinologist led me to see the impact of low Vitamin D on dialysis patients which caused Hyper Parathyroidism, bone loss and pain, requiring surgery. Renal Failure Patients can not produce D3, and the absence of D3 caused their Hyper Parathyroidism, the solution seemed obvious to me… However, the two major Nephrologists in Buffalo that I took my hypothesis to dismissed it. (What did a young Surgical Resident know…) It was another 10-20 years before the Mayo Clinic started routine D3 medication of dialysis patients to prevent the dreaded Endocrine Problem A normal vitamin D level should never be below 32 ng/ml, and any levels below 20 ng/ml are considered serious deficiency states, increasing your risk of as many as 16 different cancers and autoimmune diseases like multiple sclerosis and rheumatoid arthritis, just to name a few. Article in MedScape - Scotland , a 12 month summary of all vitamin D testing •Bone health, absorption of Calcium and Phosphate •Important to having a healthy strong Immune System •Linked to HBP, insulin resistance, Diabetes risk, Obesity •Linked to reduced inflammation, beneficial for keeping your Heart healthy & reduction of risks for several Cancers. •Massive body of scientific research links low vitamin D levels, which causes serotonin (the happy hormone) to plummet in the brain, leading to Depression. (But also low Mg and Boron!) found that Vitamin D Deficiency was linked to All-Cause Mortality. People with the lowest levels (bottom 25%) of vitamin D had a 26% increase in risk of death during the study period compared to people with the highest levels of vitamin D. •Researchers •Clearly we want our Vit. D in the “Optimal” Range! •Those who have devoted their careers to studying Vit. D suggest the Optimal Levels you should seek to maintain are in the 40-80 range. is listed as 30-100, but many individuals have levels much lower. •It is not wise to take Vit. D3 without having your blood levels checked as too much is bad for you also. •“Normal” If your MD finds your Vit. D level is low, get the actual # & explore taking 2-5,000 units a day of D3 instead of the 50,000 units once a week that commonly is recommended but often does not work. (Remember, too high is bad also!) Always request a repeat blood test in about 4-6 weeks to determine if the dose is working. Shoot for a test level in the 40-80 range and don’t settle for one that just makes it to 30. Request testing twice each year, late summer and late winter, as requirements are higher in winter (Sunshine) by usually at least 2,000 units per day. We have known that Soil Microbes play very important roles in Plant Health for some time… In early 1900’s evidence of the relationship of Human Gut Microbes tied to our Immune System Even Colon Cancer (study done in 1960’s) Now we are opening an amazing and informative window about how Gut Microbes are tied to Many (All?) Human Diseases & Illnesses! Immunology & Infectious Diseases Gastroenterology Rheumatology Diabetes Neurology and Mental Illness We may have as many as 400 Trillion Microbes! The number of Microbes is about equal to the number of Our Body Cells! While they are mostly Bacteria, there are also Fungi, Viruses, and Protozoa… Modern Hygienic practices and overuse of Antibiotics may have Weakened our Immune System Balances (Reduced Good Bacteria…) Studies show Tribes in remote areas of the World have more Diverse Microbiome's than those of Industrialized Populations. They live longer and have less DM, HD, Obesity Our “Modern Hygiene” habits (& Diets) may be weakening aspects of our Health. This also opens the possibility that there may be simple ways to intervene to correct our Health Problems? Élie Metchnikoff - Russian scientist 1845 – 1916, Worked in Louis Pasteur's Lab This Present Day Topic actually has been around for over 100 Years! This Gentleman was way ahead of his time & a great thinker “Outside The Box!” He even suggested that the reason more Agrarian populations Lived Longer and had Less Dementia might be due to the fact their diets included fermented foods rich in Probiotics! Two centuries after bacteria were discovered, the first theories of the microbiome's role in maintaining health were put forth by Élie Metchnikoff . He won a Nobel Prize in 1908 for helping to pioneer Cellular and Humeral Immunology.. This was possibly the first instance in which Probiotics (the practice of introducing micro organisms for their health benefits) were specifically offered as a medical solution. There were significant Microbe Population Differences between individuals There were certain Microbe Patterns observed with certain Diseases (Obesity, Diabetes, Arthritis…) Finally, examination of stool from random individuals could help suggest what diseases they might actually have from the types of Microbes in their gut! “Only one in 10 Americans eat recommended amounts of Fruits and Vegetables each day.” “This is Especially Concerning since decades of Nutritional Research shows increased consumption of Fruits and Vegetables can improve Health and Prevent Diseases like Cancer, Heart Disease, Diabetes and Obesity!” Studies determined differences in Gut Microbes between Lean and Obese Individuals Then they observed the profiles changed upon weight loss on a low calorie diet, demonstrating a relationship between gut flora changes with Diet Changes, and how it can effect Health. Microbiome - Is involved in complex relationships with our bodies, opening possibility of new treatment opportunities and relationships. In the 1960’s it was observed that Beef Consumption resulted in both colon bacteria changes and also Liver Bile Acid changes resulting in Carcinogens being formed in Colon by the bacteria and the different Bile Acids Rates of Colon Cancer were shown to be tied to Beef Consumption rates in different countries. Except for Argentina where the rate was half of predicted, likely due to high fruit and vegetable consumption rates there. We know High Fiber Diets of those eating lots of Fruits and Vegetables results in much larger Stool Bulk, and more Rapid Transit Times (Faster from mouth to toilet) These two factors would logically both dilute the concentration of the produced Carcinogens as well as reduce Exposure of the Colon Mucosa These simple factors resulted in Cutting Colon Cancer Risk in half. If you enjoy eating Beef be sure to eat lots of Fruits and Vegetables also! Of Course you already know that lots of Fruits and Vegetables are good for you, but it is not only because of their great Nutrient Density value! Fiber has many positive influences on Colon Health as well as Overall Health, and they are just the “Icing on the Cake” of eating lots of Fruits and Vegetables, only without the Sugar! Clostridium Difficile Infections, which have become more common and difficult to treat, now have successful treatment rates near 90% from “Fecal Transplants!” Inflammatory Bowel Disease (Crohn’s Disease & Ulcerative Colitis) may also have both diet influences as well as treatment possibilities from introducing favorable microbes. Studies have demonstrated common Gut Micro-biomes among those with RA, supporting the potential role in the cause of RA It would appear that a Genetic Predisposition might play a role also. Studies are being conducted with Probiotics Interventions to evaluate their use in treatments. Human Mother’s Milk produces a number of complex sugars, some of which are totally unable to be digested by the baby. They are likely food for Specialized Microbes in the baby’s gut which in turn produce Immuno-Potective and Anti-Inflammatory properties, benefiting the baby. Breast Fed babies’ gut microbiome are significantly different from those fed formula! A multi-country study in the US and Europe of Diabetics who were not caused by AutoImmune disease, allowed a model to be created of the Stool Microbiome Patterns differentiating between Non-Diabetics Pre-Diabetics Diabetics In China, the pattern was different, indicating possible differences due to regional diets The Mediterranean Diet, with lots of Fruits and Vegetables and rich in Boron and Magnesium, is a prime example of one that can greatly reduce one’s risk of becoming Diabetic. I decided to research how the Mediterranean Diet might have been found to influence Gut Microbes… Actually I was not surprised to find a huge number of reported studies from very recently documenting just how this all relates… The Mediterranean Diet, Disease Prevention, and changes found in Gut Microbes from following the MD vs. “Western Diets” Int. J Molecular Sci. 2014 Jul; 15(7): 11678–11699. High-level adherence to a Mediterranean diet beneficially impacts the gut microbiota and associated metabolome.[Gut. 2015] [Evidences on the relationship between Mediterranean diet and health status].[Recenti Prog Med. 2009] 'The way to a man's heart is through his gut microbiota'--dietary pro- and prebiotics for the management of cardiovascular risk.[Proc Nutr Soc. 2014] One of the most interesting findings has been the role of Microbiome in Mental Health and Neurologic Conditions! The Microbes can communicate with the Brain and Central Nervous System with Neurotransmitters to the Vagus Nerve. Certain Gut changes appear associated with Autism Spectrum Disorders. Perhaps Bipolar Disorder, Major Depressive Disorder and even Schizophrenia may be effected by gut Microbe changes The more we uncover very interesting connections and relationships! The findings and associations help us better understand how eating a Healthy Diet can actually result in chemical changes wrought by Gut Bacterial changes that can either keep us Healthy or make is ill by their influences on the different systems of our bodies! Helps us better understand how we need to do things differently to achieve health. There is much more to learn but this clearly is the next step in our understanding how our bodies work I believe that things like Vitamin D, Magnesium, and Boron intake will also soon be found to impact favorably how our gut microbes can help make us healthier too! Just as Soil Health, Soil Microbes, & Farming Methods are all related to production of Healthy Foods without the need to use Toxic Chemicals… We are seeing that consuming those Healthy Foods, in the Proper Types & mixtures, can Hugely Impact what types of Bacteria that will grow in our guts, And that the correct types of Bacteria can play Huge roles in Preventing Diseases and Preserving our Health! Conclusion… 1. Consider a Mediterranean Style Diet (Available on line) A glass of red wine 1-2 X a day fits in nicely with this! 1. Consider Mg Gluconate 550 mg supplement 2. Get your blood Vitamin with each meal. D level checked 2 X a year . 4. If your level is low, consider Monitored use of D3 (blind is not wise) 5. Consider Boron Complex 3 mg. with each meal. 6. Remember, Exercise, Weight & Stress Management, and adequate Sleep are also very important as well! 5 cents per pill 2.5 cents per pill 5 cents per pill This comes to about $10/month! Today‘s PowerPoint available on my Website! My Business Cards w/ website are available! Go to Home Page, Select “Menu” and then select “Nutrition” Today’s Hand Out is the first item. The PowerPoint “Circle of Life” is next, you can Share it with your Friends & Family Followed by a long Bibliography with “HyperLinks of studies and articles documenting things I have stated in my presentation. Thank You for coming! I hope you learned something to benefit your lives and health!