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Personality Disorders 3FM CU Module Neurobehavioural Sciences II 5th year Practice Barbora Kohútová Personality Disorders (PD) CONTENTS: • Personality: definition, structure, historical development of typology and classification • PD: definition, classification according to DSM-IV and ICD-10 • Specific PD: general and specific diagnostic criterions, clinical picture • PD: Diagnostics, differential diagnostics • Etiology and pathogenesis • Treatment: psychotherapy and psychopharmacology Definitions of personality • A dynamic and organized set of characteristics possessed by a person that uniquely influences his or her cognitions, motivations, and behaviors in various situations. → A relatively stable and enduring set of characteristic behavioral and emotional traits (the set of emotional qualities, ways of behaving, etc.) that makes a person different from other people. It manifests itself in sociocultural enviroment. • Personality is thought to be determined by genetics and biology, and its developement is completed by environment and experiences • around 50% of personality traits is genetically determined Components of personality Temperament Biological component Character Social and psychological component Intelligence modifies both these basic components TEMPERAMENT • Congenital component of personality (particuraly genetically determined) • „temper“, „excitability“ • It is related to way of emotional manifestation in specific situations CHARACTER • Aquired component of personality • „nature“ • Arises during early developement by psychosocial learning (mental maps) • Moral and behavioral traits in sociocultural enviroment Personality typology: historical viewpoint • Hippokrates: – Sanguine, Melancholic, Choleric, Phlegmatic • • C.G.Jung: – Extraverted / Introverted 460-377 BC Kretschmer (constitutional body types 1875 - 1961 associated with certain personality traits ): – asthenic/leptosomic (thin, small, weak), athletic (muscular, large–boned), and pyknic (stocky, fat) • 1895-1978 Vondráček: – Dysthymia, Cyclothymia 1888-1964 Personality typology: historical viewpoint Hans Eysenck (1916-1997) - 1947 he described two personality dimensions: extraversion and neuroticism (E and N) • High N and high E = Choleric type – emotionall unstable extraverted • High N and low E = Melancholic type – emotionall unstable introverted • Low N and high E = Sanguine type – emotionall stable extraverted • Low N and low E = Phlegmatic type – emotionall stable introverted What does personality disorder („psychopathy“) mean? • An enduring pattern of inner experience and behavior that deviates markedly from the expectations of the individual’s culture, – – – – is pervasive and inflexible, has an onset in adolescence or early adulthood, is stable over time, and leads to distress or impairment • It is not „mental illnes“ in the right meaning • People with personality disorder are not matured, they are lacking in empathy and fail in interpersonal relationship. Definition of PD due to DSM-IV An enduring pattern of inner experience and behavior that deviates markedly from the expectations of the individual's culture. This pattern is manifested in two (or more) of the following areas: – Cognition (i.e., ways of perceiving and interpreting self, other people and events) – Affectivity (i.e., the range, intensity, liability, and appropriateness of emotional response) – Interpersonal functioning – Impulse control • DSM-5: Latest revision of DSM, May 2013 DSM-5: definition of PD The essential features of a personality disorder are • impairments in personality – self functioning – interpersonal functioning • the presence of pathological personality traits Specific P.D.: 10 types, each type is defined by a specific pattern of impairments and traits. DSM-5: General Criteria for a PD • • • Significant impairments in self (identity or selfdirection) and interpersonal (empathy or intimacy) functioning. One or more pathological personality trait domains or trait facets. These changes – are relatively stable across time and consistent across situations – are not better understood as normative for the individual‟s developmental stage or socio-cultural environment – are not solely due to the direct physiological effects of a substance (e.g., a drug of abuse, medication) or a general medical condition (e.g., severe head trauma) Specific PD 10 distinct types of P.D. (3 basic clusters) • A - Odd or Eccentric: – Paranoid – Schizoid – Schizotypal • B – Dramatic or Erratic: – – – – Antisocial Narcissistic Borderline Histrionic • C- Anxious: – Avoidant – Dependent – Obsessive-compulsive The hybrid methodology for clinicians (6 types): • • • • • • Borderline Obsessive-Compulsive Avoidant Schizotypal Antisocial Narcissistic • PD-TS (personality disorder – trait specified) - PD is present, but the criteria for a specific personality disorder are not fully met (must be noted) Highlights of differences between DSM-5 and ICD-10 classifications • ICD-10: 10 + 1 basic types – Paranoid, Schizoid, Antisocial, Histrionic, Emotional unstable, Avoidant, Anankastic (Obsessive–compulsive), Narcissistic, Pasive-agressive PD + Schizotypal disorder – Schizotypal disorder is not in PD (F6x), but in psychotic disorders (F2x) – Emotional unstable PD (F60.4) is divided into impulsive and borderline type – Narcissistic and passive-aggressive PD are cathegorized in Others PD (F61) • DSM-5: 10 basic types – Passive-aggressive PD is not described – Emotional unstable, respectively Impulsive PD is not described (only Borderline PD) Paranoid PD • Pervasive distrust • Suspiciousness of others • Touchiness • They believe that other people’s motives are suspect or even malevolent • Distortion and wrong interpretation of neutral or friendly motives as unfriendly or contemptuous • Jealousy - they suspect their partner from infidelity Criteria of Paranoid PD • Pervasive Distrust • Suspiciousness • Interpret Motives as Evil • • • • • Feels Attacked Preoccupation with Distrust Jealous Won’t Confide Misinterprets Motives Schizoid PD • Detached • Few emotions - emotionally cold • • • • • • • Closeness No Close Friends Solitary Indifferent, cold Low Sex Interest They don´t enjoy activities Unrealistic phantasies, goals, „inner world“ „Party at the Technical University“ Schizotypal PD: DSM-5 Criteria • Eccentricity – Odd, unusual, or bizarre behavior or appearance; saying unusual or inappropriate things • Cognitive and perceptual dysregulation – Odd or unusual thought processes; vague, circumstantial, metaphorical, over-elaborate, or stereotyped thought or speech; odd sensations in various sensory modalities • Unusual beliefs and experiences – Thought content and views of reality that are viewed by others as bizarre or idiosyncratic; unusual experiences of reality Antisocial PD • Disregard rights and emotions of others • Disorderly conduct • Unlawful • Irresponsible • Impulsive • Lack Remorse • Aggressive • „Criminal types“ • „Psychopaths“ DSM-5 Criteria of Antisocial PD • Antagonism – Manipulativeness – Deceitfulness: Dishonesty and fraudulence – Callousness: Lack of concern for feelings or problems of others; lack of guilt or remorse about the negative or harmful effects of one„s actions on others; aggression; sadism – Hostility: Persistent or frequent angry feelings; anger or irritability in response to minor slights and insults • Disinhibition – Irresponsibility – Impulsivity: Acting on the spur of the moment in response to immediate stimuli; acting on a momentary basis without a plan or consideration of outcomes – Risk taking Borderline PD • Unstable emotional experiences • Frequent mood changes • Unstableself-image, often associated with excessive selfcritisism • Chronic feeling of emptiness • Intense, unstable, and conflicted close relationships DSM-5 Criteria of Borderline PD • Negative Affectivity – Emotional lability: Unstable emotional experiences and frequent mood changes – Anxiousness: Intense feelings of nervousness, tenseness – Separation insecurity: Fears of rejection – Depressivity: Frequent feelings of being down, miserable, and /or hopeless • Disinhibition – Impulsivity: self-harming behavior under emotional distress – Risk taking: Risky, and potentially self-damaging activities • Antagonism – Hostility: Persistent or frequent angry feelings „SPLITTING“ Self-harm, self-injury • It is performed on the grounds of: – release of inner tension – cover of feelings of emptiness – cover of emotional pain with physical pain • It is not: – attraction of sb's attention – suicidal behaviour Self-harming Histrionic PD • • • • • • Self-dramatization Excessive emotions Attention seeking Suggestibility Exaggerating Inappropriate seductiveness • „drama-queen“ Obsessive-Compulsive PD • „punctiliouos“ • concerned with details • perfectionism • rules, perfect order, lists DSM-5 Criteria of Obsessive-Compulsive PD • Compulsivity – Rigid perfectionism: Rigid insistence on everything being flawless, perfect, without errors or faults, preoccupation with details, organization, and order • Negative Affectivity – Perseveration: Persistence at tasks long after the behavior has ceased to be functional or effective; continuance of the same behavior despite repeated failures Avoidant PD • Excessive feelings of shame or inadequacy • • • • • • • • Avoids Social Activity Reluctant Relationships Fears Intimacy Fears Criticism Avoids New Activities Sees Self Inferior Fears Embarrassment DSM-5 Criteria of Avoidant PD • Withdrawal – avoidance of social contacts and activity; lack of initiation of social contact • Intimacy avoidance – avoidance of close or romantic relationships • Anhedonia – lack of enjoyment from, engagement in, or energy for life‟s experiences • Anxiousness – intense feelings of nervousness, tenseness, or panic, often in reaction to social situations; worry about the negative effects of past unpleasant experiences and future negative possibilities Dependent PD • Needs to be taken care of • Fears separation • Dependence inclination • often „role of victim“ Narcissistic PD • „self-love“ • Excessive reference to others for self-definition and selfesteem regulation • Exaggerated self-appraisal • Impaired ability to recognize or identify with the feelings and needs of others DSM-5 Criteria of Narcissistic PD • Grandiosity – Feelings of entitlement, either overt or covert; selfcenteredness; firmly holding to the belief that one is better than others; condescending toward others. • Attention seeking – Excessive attempts to attract and be the focus of the attention of others; admiration seeking. Passive-aggressive PD • Undirect complaints • Sabotage of teamwork • Intransigence • Unproductivity Mixed PD • Common in clinical practice • Examples of combination of personality traits: – histrionic + narcissistic – avoidant + obsessive-compulsive – narcissistic + antisocial – paranoid + antisocial Diagnostics of PD • Diagnostic tools – psychiatric investigation – structured interviews – psychological assessment (objective qustionnaire) • MMPI: Minnesota Multiphasic Personality Inventory • MCMI: Millon Multiaxial Inventory • TPQ Cloningerův trojrozměrný dotazník – Neuropsychological test: diagnostics of organic disorders • Dg. of adult age, at least 18 years Etiology a pathogenesis of PD • Multifactorial • Biological influence: – genetics – perinatal injury – stress in gravidity – brain inflammations • • frontal cortex – impulsivity, judgment, abulia temporal cortex – excitability, psychomotoric restlessness, religiosity • parietal cortex – euforia, refusing Etiology a pathogenesis of PD • Psychological theories • Psychoanalytical - Freud – Oral ( oral personality) 0-1 year – Anal ( anal personality) 1-2 years – Uretral 2-3 years – Phallic 3-6 years – Latence stage 6-12 let – Genital 12 years - adult Neurobiology of PD Symptoms PD Neurobiological changes ↑impulsivity Emotional lability Borderline Antisocial ↑ limbic cortex (amygdala) ↓ prefrontal inhibition ↓ serotoninergní aktivity prefrontálně Cognitive dysregulation and information processing Schizotypal Paranoid (Schizophrenia) ↑ dopaminergic activity limbic area ↓ dopaminergic activity prefrontally anxiety Avoidant ↑ activity amygdala Obsessive-compulsive ↓ activity prefrontal cortex Treatment PD • Combination of pharmacotherapy and psychotherapy • Goal of the treatment determination – Crisis intervension • Suicidal tendencies, self-harming, aggression – Short-therm treatment of acute comorbid disorder (personality decompensation) • Depressive, anxious, psychotic – Long-therm treatment of PD Possibilities od treatment of PD • Pharmacotherapy • Supporting psychotherapy • Dynamic psychotherapy • Cognitive-behavioral psychotherapy (CBT) • Group psychotherapy Common treatment process • Symptomatic pharmacological treatment of acute symptoms – depressive, anxious, psychotic symptoms, .. – symptoms-related pharmacotherapy (antidepressants, antipsychotics, mood stabilizers) • Long-therm psychotherapy treatment of PD – It takes years, individual od group form of psychotherapy Symptomatic pharmacotherapy Neurotransmiter Peronality dimension Disordes Primary therapy Dopamin (D) ↑D Cognition / perception Schizophrenia SchizotypalPD Paranoid PD AP Serotonin (5-HT) ↓ 5-HT Impulsivity / aggressivity Antisocial PD Borderline PD Gambling SSRI Affective disorders (BAP) Borderline PD Mood-stabilizers AD Noradrenalin (NA) Affectivity regulation ↑ NA Inspired by: Dušek, Večeřová, 2010 Děkuji za pozornost. 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