Download Total Thyroid #2 A comprehensive and unique formula developed

Total Thyroid #2
A comprehensive and unique formula developed especially for superior support of the Thyroid Gland.
The thyroid controls energy and
metabolic rate
The thyroid regulates the basal metabolic rate of almost every cell
in the body. If the thyroid isn’t functioning right, our metabolism
isn’t functioning right. Metabolism in the cell is needed for every
biochemical reaction that happens in our body. These reactions
include: digestion, elimination, body temperature regulation,
protein-building (including hormones, antibody formation and cell
receptors), calorie-burning, nerve conduction, brain neurotransmitter
production, energy creation (hypothyroidism is often the reason for
fatigue), enzyme formulation, and many other important functions.
Hypothyroidism can cause you to feel “off”.
Symptoms of low thyroid function include: weight gain, fatigue, muscle
weakness, cramps, appetite loss, slow heart rate, low body temperature,
sensitivity to cold, hair loss, dry skin, constipation, slow speech, difficulties
in concentration, depression, irritability, painful periods, drooping swollen
eyes, bumps on eyelids, swollen face, increased allergies, recurrent
infections, goiter, and calcium metabolism problems.
Books have been written about how rampant hypothyroidism is, and about
how difficult it is to diagnose when limiting lab analysis to one value (called
The thyroid controls immune
TSH, or thyroid stimulating hormone), which doesn’t really give you a
system metabolism
detailed picture of what’s going on in the thyroid. “Subclinical
hypothyroidism” is associated with all-cause mortality. Subclinical values aren’t “optimal” but escape the radar
because they aren’t “out of lab range”. Many people have subclinical hypothyroidism and don’t even know it,
because they don’t get red flags on their lab tests. Comprehensive
testing is recommended (including tests for the actual thyroid
hormones and thyroid antibody production).
Thyroid hormones operate in a complex hormonal environment
that includes multiple organs and hormones, along with
neurotransmitters such as serotonin. Dr. Winifred Cutler, the
biologist, calls this the "Hormonal Symphony." When thyroid
The thyroid controls
hormones are low it affects sex hormones adversely, particularly
nerve metabolism
progesterone, and can lead to estrogen dominance.
Sometimes hypothyroidism is caused by an autoimmune attack on the thyroid, where antibodies destroy
important thyroid molecules. This is why it is important, in any thyroid support product, to include nutrition to
support homeostasis and regulation of the immune system. .
Ashwagandha: In pre-clinical trials, it was revealed that ashwagandha “stimulates thyroidal activity and
also enhances the antiperoxidation of hepatic tissue hormone”, and that T-3 and T-4 (thyroxine), both thyroid
hormones, were increased by ashwagandha (J Pharm Pharmacol. 1998 Sep;50(9):1065-8; J Ethnopharmacol. 1999 Nov 1;67(2):2339.) Ashwagandha has also been found to be a potent antioxidant that prevents lipid peroxidation, and hence
damage of thyroid tissue due to oxidation. This can be really important when you consider that Hashimoto’s
(autoimmune hypothyroidism) is a condition of antibody production that can be increased during
oxidation/damage of thyroid tissue (Pharmacol Res. 2000 Jun;41(6):663-6.) Ashwagandha “potently inhibits
proinflammatory cytokines” (Drug Discov Ther. 2011 Aug;5(4):195-201.) Ashwagandha improves immune system
function and leads to improved “haematological, biochemical and immunological parameters” when
supplemented (Fish Shellfish Immunol. 2012 Mar 6.) It is believed that ashwagandha may even have neuroprotective
benefits (Hum Exp Toxicol. 2005 Mar;24(3):137-47).
Larch Arabinogalactan is commonly used to support the immune system and also to support the thyroid.
Larch is composed of greater than 98-percent arabinogalactan, making it an excellent source for this powerfully
functional nutrient. It is an excellent source of dietary fiber, and has been approved as such by the FDA. It has
been shown to increase the production of short-chain fatty acids, principally butyrate and propionate, and has
been shown to decrease the generation and absorption of ammonia. Butyrate is the main fuel for large intestine
cells. Evidence also indicates human consumption of larch arabinogalactan has a significant effect on
enhancing beneficial gut microflora, specifically increasing Bifidobacteria and Lactobacillus (Altern Med Rev. 1999
Apr;4(2):96-103.) In a randomized, double-blind, placebo-controlled, prospective four-week clinical trial,
arabinogalactan was found to possess immunomodulating properties (Altern Med Rev. 2007 Mar;12(1):25-48.)
Guggul Extract: NIEHS (a division of National Institutes of Health) reported in Feb 2005 that guggul
extract (gum) is increasingly being used as a dietary supplement and that “biological effects have been
demonstrated on lipid metabolism, thyroid hormone homeostatsis, female reproductive tissues, and
endogenous nuclear hormone receptors” (they also reported “anti-inflammatory activity” in pre-clinical trials)
(Masten, SA., PhD. Gum Guggul and Some of Its Steroidal Constituents Feb. 2005. NTP/NIEHS Research Triangle Park, NC).
Guggul supplements are reported to help regulate thyroid function and improve hypothyroidism, according to
pre-clinical trial studies (S. Panda et al. Phototherapy Research. January 2005; (Tripathi YB, et al. Thyroid stimulating action of Zguggulsterone... Planta Med . 1984;50(1):78-80.) Dr. Richard B. Kreider, author of the book "Exercise and Sport
Nutrition," also states that guggulsterones, found in guggul, have the ability to increase the output of the thyroid
gland and stimulate the conversion of the T4 thyroid hormone into its more active T3 form (Exercise & Sport
Nutrition: Principles, Promises, Science, & Recommendations; Richard B. Kreider et al.; 2009.) Increased T3 can help increase
metabolism and burn fat. The University of Maryland Medical Center recommends 25 mg of guggulsterones
three times daily to lower the high cholesterol levels associated with hypothyroidism.
Exciting research may be able to confirm that guggul naturally regulates a gene receptor called farnesoid X
receptor (FSX) which controls metabolism in the liver.
The iodine molecule is needed for the synthesis of the thyroid hormones. In fact, three iodine molecules are
added to the thyroid hormone T3 and four iodine molecules are added to T4. The fact that iodine insufficiency
is rampant, coupled with the necessity of iodine to produce thyroid hormones contributes to widespread
hypothyroidism.
Coleus Forskohlii raises cyclic AMP (which raises metabolism) in many systems, including endocrine
tissues such as the thyroid gland by acting at a post-surface receptor site on the thyroid (Ealey PA, et al. (Acta
Endocrinol (Copenh). 1985 Mar;108(3):367-71.) This increased metabolic rate is being researched for its effect on
thermogenesis, weight management and thyroid function. Cyclic AMP and the chemicals it activates comprise
a second messenger system that is responsible for carrying out complex and powerful effects of hormones in the
body. The forskolin in coleus forskohlii is believed to stimulate secretion of T3 and T4 in a manner similar to
TSH because of its effect on cyclic AMP (Venkateswaran A. et al. J Clin Endocrinol Metab. 2004 Dec;89(12):6168-72; Laurberg P.
Forskolin stimulation of thyroid secretion of T4 and T3. FEBS Lett. 1984 May 21;170(2):273-6; Hiraiwa M. Nippon Naibunpi Gakkai Zasshi. 1987
Jan 20;63(1):34-44) and also to stimulate iodine metabolism (iodine is needed to make thyroid hormones) (van Sande
J, et al. Forskolin stimulates adenylate cyclase and iodine metabolism in thyroid. FEBS Lett. 1982 Dec 13;150(1):137-41.)
The following abstract points out that iodine is an antioxidant, that mg doses are safe (and effective) and that
iodine has an important role in maintaining normal breast tissue as well as supporting the thyroid.
“Iodine deficiency is generally recognized as the most commonly preventable cause of mental retardation and
the most common cause of endocrinopathy (goiter and primary hypothyroidism). Iodine deficiency becomes
particularly critical in pregnancy due to the consequences for neurological damage during fetal development as
well as during lactation. The safety of therapeutic doses of iodine above the established safe upper limit of 1 mg
is evident in the lack of toxicity in the Japanese population that consumes 25 times the median intake of iodine
consumption in the United States. Japan's population suffers no demonstrable increased incidence of
autoimmune thyroiditis or hypothyroidism. Studies using 3-6 mg doses to effectively treat fibrocystic breast
disease may reveal an important role for iodine in maintaining normal breast tissue architecture and function.
Iodine may also have important antioxidant functions in breast tissue and other tissues that concentrate iodine
via the sodium iodide symporter” (Patrick, L. Altern Med Rev. 2008 Jun;13(2):116-27.)
Ginseng has been traditionally used for thyroid support for many years. American Ginseng and Eleuthero
(Siberian ginseng) are known as adaptogens and have been utilized traditionally for many years as thyroid
support. An adaptogen is defined as an agent that helps to bring the body’s organ systems into homeostasis,
whether function is high or low.
Selenium is a mineral that is absolutely essential for proper thyroid function. Selenium is highly concentrated
in the thyroid gland, more so than in any other organ in the human body, indicating its role in normal thyroid
function. It acts as an antioxidant that protects the thyroid gland, a cofactor nutrient that facilitates the
production of thyroid hormone, and as a nutrient that is required to facilitate the conversion of T4 to T3 and also
prevent the conversion of T3 into inactive, or reverse T3. Hypothyroidism can arise from many causes,
however when the cause is an overabundance of reverse T3 many times the simple solution is providing enough
selenium for this conversion.
L-Tyrosine is an amino acid that is crucial to thyroid hormone production. It is not only needed for thyroid
hormone production, the tyrosine molecule is incorporated tight into the thyroid molecule. Tyrosine converts to
dopamine and norepinephrine with the help of vitamin B6 and vitamin C. Norepinephrine is a neurotransmitter
that can stimulate the hypothalamus and pituitary to activate the production of thyroid hormone (through TRH
and TSH).
Yellow Dock is an herb which has practical applications in metabolism function, due to its high content of
valuable minerals which affect thyroid health. Yellow Dock is a blood purifier that has a special synergistic
function with iodine when it comes to the thyroid gland.
Gotu Kola has a long history of use in Ayurvedic medicine with many traditional indications. One of the
indications for gotu kola is thyroid support. In addition to all of these synergistic herbs and nutrients, Total
Thyroid #2 contains a blend of glandular support that ties in multiple organ systems that depend on each other
to operate at full speed, including thymus, spleen, pituitary, adrenal and parotid.
Additionally, Total Thyroid #2 is packed full of the vitamins and minerals that together ensure optimal
function of the thyroid gland, including: Vitamin B-1, Vitamin B-2, Vitamin B-6, Vitamin B-12, Vitamin A,
beta carotene, Vitamin C, Niacin, Folic acid, Calcium, Manganese, Molybdenum and Zinc.
Contraindications: Check with your doctor if you are on thyroid medication. If supplementation increases
thyroid activity it may be necessary to adjust the thyroid meds. Do not take with MAO inhibitors, blood
thinners or in pregnancy.
Total Thyroid #2 Ingredients: Ashwagandha Extract (root) 200 mg, Larch Arabinogalactan 100 mg,
Guggal Extract (gum) 25 mg, American Ginseng (root) 20 mg, Eleuthero (root) 20 mg, Yellow Dock (root) 5
mg, Gota Kola (herb) 5 mg, Coleus Forskohlii Extract (root) 25 mg, Vitamin A (as palmitate) (1% as Beta
Carotene) 505 IU, Vitamin C (as ascorbic acid) 50 mg, Calcium (as chelate) 25 mg, Thiamine (as
hydrochloride) 5 mg, Riboflavin 5 mg, Niacin 2 mg, Vitamin B6 (as pyridoxine hydrochloride) 5 mg, Folate (as
folic acid) 100 mcg, Vitamin B-12 (as methylcobalamin) 100 mcg, Iodine (as kelp, potassium iodide) 1530
mcg, Zinc (as chelate) 1.5 mg, Selenium (as methionine) 200 mcg, Manganese (as chelate) 0.800 mg,
Molybdenum (as chelate) 30 mcg, Thymus (bovine) 40 mg, Spleen (bovine) 10 mg, Pituitary (bovine) 3 mg,
Adrenal (bovine) 10 mg, Parotid (bovine) 3 mg, L-Tyrosine 50 mg, Choline (as bitartrate) 25 mg, Betaine (as
hydrochloride) 25 mg.
Compliments of
NUTRI-WEST BLUE RIDGE
800-334-3793 or 843-342-3688
www.nutriwestblueridge.com
The above statements have not been evaluated by the FDA. The nutritional information, suggestions, and
research provided are not intended to diagnose, treat, cure, or prevent disease and should not be used as a
substitute for sound medical advice. Please see your health care professional in all matters pertaining to your
physical health.