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Exercise 2 Deadline 8th November 4:15 pm 1 Nicotine is a drug that is derived from the tobacco plant. It acts as a receptor agonist for nicotinic acetylcholine receptors. The ventral tegmental area is responsible for dopamine release. These dopamine neurons also have nicotinic acetylcholine receptors. Presence of nicotine will increase the dopamine release. The exact process of how dopamine works is unknown, but we know that people when able to choose do things that release dopamine. It’s a sort of reward system, but with overuse, this gets downregulated, and the result is a need for larger intake of nicotine. (p 569, 175, 193) 2 a) b) Ipsilateral means that something exist on the same side laterally. Contralateral means that is placed on the opposite side. CSF is short for cerebrospinal fluid. It is found in CNS and flows through the ventricular system to the subarachnoid space. The fluid is produced by the choroid plexus. PNS is short for the peripheral nervous system and it consists of all parts of the nervous system except for the brain and spinal cord. ANS ont he other hand is short for the autonomic nervous system. It’s the involuntary part of PNS and as such controls the internal organs, blood vessels and glands. Afferent is term used to describe when something brings information to somewhere while efferent is used when something brings information from somewhere. 3 The frontal lobe is one of the four lobes (frontal, temporal, parietal and occipital) that divide the cerebral cortex. It is located in the forehead under the frontal bone. The posterior border of the frontal lobe is the central sulcus. Caudal to the frontal lobe lies the parietal lobe. The lateral Sylvian fissure and the insula separates the frontal lobe from the temporal lobe. Basal forebrain lies dorsal to the frontal lobe. The frontal lobe can be divided into two parts the prefrontal cortex and the motor cortex. The frontal lobe is larger in humans than in most other animals. It’s function is not very well known, but researchers suspect that it is responsible for what makes us human. Examples of these features are complex planning and, self awareness and problem solving. This means that the frontal lobe also is important for learning and memory. In left frontal lobe lies Brocas area which is responsible for language and speech. Lesions in the frontal lobe can lead to drastic personality changes. The motor are can be divided into primary motor area 4 and supplementary motor and premotor area 6. These area are involved in conscious moving. 4 P 251 1 temporal lobe 2 frontal lobe 3 parietal lobe 4 occipital lobe 5 insula 6 auditory cortex 7 inferotemporal cortex 8 prefrontal cortex 9 Premotor area 10 supplementary motor area 11 primary motor cortex 12 somatosensory cortex 13 posterior parietal cortex 14 visual cortex 15 gustatory cortex P 252 1 Medulla 2 pons 3 tectum 4 tegmentum 5 midbrain 6 hypothalamus 7 thalamus 8 pineal body 9 cerebellum 10 optic chiasm 11 olfactory bulb 12 formix? 13 cingulate gyrus 14 corpus callosum 15 calcarine fissure 16 hippocampus 17 amygdala P 253 1 spinal cord 2 fourth ventricle 3 cerebral aqueduct 4 third ventricle 5 lateral ventricle 6 medulla 7 cranial nerves 8 optic nerves 9 olfactory bulb 10 optic chiasm 11 optic tract 12 hypothalamus 13 mammillary body 14 midbrain 15 pons P 254 1 longitudinal cerebral fissure 2 central sulcus 3 left hemisphere 4 right hemisphere 5 corpus callosum 6 left cerebellar hemisphere 7 vermis 8 right cerebellar hemisphere 9 spinal cord 10 pons 11 midbrain 12 thalamus 13 pineal body 14 superior colliculus 15 inferior colliculus 16 cerebellar peduncle 17 fourth ventricle P 256 1 hypothalamus 2 basal forebrain 3 temporal lobe 4 lateral (Sylvian) fissure 5 insula 6 frontal lobe 7 lateral ventricle 8 thalamus 9 third ventricle 10 internal capsule 11 cortical white matter 12 formix 13 corpus callosum 14 cerebral cortex 15 septal area 16 caudate nucleus 17 putamen 18 globus pallidus P 256 1 hypothalamus 2 basal forebrain 3 temporal lobe 4 insula 5 thalamus 6 parietal lobe 7 lateral fissure 8 lateral (Sylvian) fissure 9 third ventricle 10 subthalamus 11 substantia nigra 12 amygdala 13 globus pallidus 14 putamen 15 ventral posterior nucleus 16 ventral lateral nucleus 17 corpus callosum 18 fornix 19 cerebral cortex 20 caudate nucleus 21 internal capsule 22 cortical white matter 23 mammillary body P 257 1 midbrain 2 temporal lobe 3 thalamus 4 third ventricle 5 parietal lobe 6 lateral ventricle 7 cerebral aqueduct 8 cortical white matter 9 corpus callosum 10 cerebral cortex 11 pulvinar nucleus 12 lateral geniculate nucleus 13 hippocampus 14 medial geniculate nucleus P 258 1 Red nucleus 2 substantia nigra 3 periaqueductal gray 4 superior colliculus 5 cerebral aqueduct 6 substantia nigra 7 periaqueductal gray 8 inferior colliculus 9 cerebral aqueduct 10 pontine nucleus 11 pontine reticular formation 12 deep cerebellar nuclei 13 cerebellar cortex 14 fourth ventricle P 259 1 medullary pyramid 2 inferior olive 3 superior olive 4 raphe nucleus 5 ventral cochlear nucleus 6 dorsal cochlear nucleus 7 fourth ventricle 8 medullary pyramid 9 medial lemniscus 10 inferior olive 11 medullary reticular formation 12 nucleus of the solitary tract (gustatory nuleus) 13 vestibular nucleus 14 fourth ventricle 15 medullary pyramid 16 medial lemniscus 17 dorsal column nuclei 18 spinal canal P 260 1 spinal dura mater 2 spinal arachnoid 3 subarachnoid space 4 spinal pia mater 5 ventral column 6 ventral horn 7 lateral column 8 dorsal horn 9 dorsal columns 10 spinal cord 11 lateral horn 12 dorsal root filaments 13 dorsal root 14 dorsal root ganglion 15 spinal nerve 16 ventral root 17 ventral root filaments 18 spinothalamic tract 19 dorsal column 21 ascending sensory pathways 21 descending motor pathways 22 corticospinal tract 23 rubrospinal tract 24 lateral pathway 25 medullary reticulospinal tract 26 tectospinal tract 27 pontine reticulospinal tract 28 vestibulospinal tract 29 ventromedial pathway P 261 1 olfactory 2 optic 3 oculomotor 4 trochlear 5 trigeminal 6 abducens 7 facial 8 auditory-vestibular 9 glossopharyngeal 10 vagus 11 spinal accessory 12 hypoglossal