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Unit 1: Energy Flow and Cellular Matter Cellular Chemistry: Metabolism: sum of all chemical reactions that occur within the cell. Catabolism: chemical reactions in which complex molecules are broken down into smaller compounds. Anabolism: chemical reactions where simple molecules are combined together to form more complex compounds. Organic Chemistry: Chemistry of carbon ~ hydrocarbons (HC’s) Carbohydrates: sugars (CHO) ending of OSE Role: Structure: cell wall in plant cells ~ cellulose. Function: energy. Monosaccharides: simple single sugars ~ C3 to C10 Disaccharides: double sugars that are combinations of single sugars. Polysaccharides: many sugars. General formula (C6H10O5). o Cellulose (dietary fibre) Starch ~ plant storage carbohydrate. Glycogen: animal starch ~ animal storage liver and muscles. Chemical Tests: Starch Test: drops of iodine solution; blue or black color indicates presence of starch. Reducing (mono & diasaccharide) Sugar: drops of Benedict’s solution. Lipids: (CHOP) ending of OL Role: Structural: phospholipids in cell membranes and fat deposits for physical protection. Functional: fat deposits for heat insulation and long term storage of energy. Triglycerides: union of glycerol and three fatty acids. o Fats: animal lipids composed of glycerol and saturated fatty acids. o Oils: plant lipids composed of glycerol and unsaturated fatty acids. Phospholipids: phosphate molecule is attached to the glycerol molecule making the molecule polar. Major components to cell membranes in animals and plants. Chemical Test: Lipids Test: 1. Grease spot test on brown paper, translucent result indicates fat or oil. 2. Add a trace of Sudan IV stain that is only soluble in lipids: color will show. Proteins: structural components of cells. (CHONS) ending of IN Roles: Structural: cell membrane and determine the shape of cells. Functional: enzymes control all chemical reactions, hormones, and energy. Very large macromolecules composed of Amino Acids. Amino Acid ~~~ peptide bond ~~~~ Amino Acid Primary Structure: polypeptide chain O-O-O-O Secondary Structure: coil made of weak hydrogen bonds Tertiary Structure: unique 3-dimensional structure allows proteins to become very specific and determines largely the properties of that protein. o This process is called Denaturation ~ uncoiling the protein shape. Caused by environmental agents: Heavy metals ~ Pb and Hg. Electricity ~ electrocution Heat ~ cooking eggs or fever pH Sometimes if the agent is removed the protein can recapture its shape, if not the permanent change is referred to Coagulation. Chemical Test: Protein Test: drops of Biuret Reagent (test for the peptide bond), a violet color indicates the presence of protein. Chemical Processes: Dehydration Synthesis: combination of simple molecules to form larger, macromolecules which yields a water molecule. Hydrolysis: breaking down of a macromolecule to form simpler, micromolecules through the addition of water. Enzymes: “lock and key” hypothesis. Suffix ~ ase Protein Reactant : 2 Glucose Must stretch to + Active Site Enzyme (maltase) + H2O break the bonds Complementary Shape Substrate (Maltose) Enzyme/Substrate Complex Enzyme Product Induced fit hypothesis. Substrate and enzyme must stretch and strain to fit. The strain breaks the bonds. Characteristics of Enzymes: Proteins Needed in small quantities (reuseable) Substrate specific Action is reversible Organic catalysts Great energy Of activation Less energy of activation No Enzyme Enzyme Allow chemical reactions to proceed under “milder” conditions in terms of temperature and pH. Have optimum pH and temperature where they are most effective or work the best. Temperature Reaction Rate pH Opt. Reaction Rate Temp. pH Rate is regulated by the relative amounts of enzyme and substrate. High (150) Reaction Rate Low Enzyme (100) Concentration of Substrate Co-Enzyme: Chemical molecules, such as a vitamin, which are needed to alter the active site of enzymes to correctly fit it with the substrate. Competitive Inhibition: Interference, caused by a non-substrate, with the active site of an enzyme or a specific site on a substrate. This chemical interference prevents the normal chemical reaction that involves that enzyme. Non-Competitive Inhibition: A process where a substance that doesn’t resemble the substrate at all attaches to the enzyme (not on its active site) which rearranges the enzyme rendering it useless. Negative Feedback ~ Homeostasis: The ability of the body to keep the normal internal body environment in a stable state even as the external environment is changing. Stops a process Positive Feedback ~ Precursor Activity: Activation of the last enzyme in a pathway due to a build up of the initial substrate. Starts a process Biology 20: Unit 2 Cellular Respiration and Photosynthesis Cell Organelles: Cell membrane: controls what comes in and out of the cell. Cytoplasm: solution within the cell. Endoplasmic reticulum (ER): contain ribosomes which are responsible for protein synthesis. Golgi Apparatus: prepare materials for secretion (proteins or enzymes). Lysosomes: Digestive enzymes Mitochondria: produces most of the cell’s energy, has its own DNA. Plastids: plants only, sites of photosynthesis, has its own DNA. Vacuoles: storage deposits Cilia and Flagella: movement of the cell. Microfilaments and Microtubules: movement of materials within the cell and movement of the cell itself. Cell Wall: plants only, supports the cell. Nucleus: determines the shape, metabolism, and heredity of the cell (DNA). Movement through the Cell Membrane: Passive Transport: Diffusion: movement of materials from an area of high concentration to an area of low concentration. Facilitated diffusion: macromolecules that are recognized by proteins on the membrane guide the molecules into the cell using passive transport. Osmosis: movement of water across a semi-permeable membrane from an area of low solute concentration to high solute concentration. o Isotonic – solution on both sides have the same concentration of water. Hypotonic solution: solution with less solute concentration and more water. Hypertonic: solution with more solute and less water Active Transport: similar to facilitated diffusion but the movement of the molecules requires the cell to use energy. o Endocytosis: large particle is engulfed by the cell Pinocytosis: small particles engulfed by the cell Phagocytosis: large particles engulfed by the cell. o Exocytosis: vacuole moves toward the cell membrane and dumps the contents out. o Ion Pump: small ions move against the gradient ATP: Adenosine Triphosphate (ATP) is the storage form of energy for cellular activity. High energy bond between the second and third phosphate group. Once broken the energy released is transformed and used within the cell. Anaerobic Metabolism: ~ absence of oxygen Glucose Glucose 2 lactic acid Alcohol + CO2 + + 6 ATP ~ animals 6 ATP ~ plants = fermentation Aerobic Metabolism: ~ presence of oxygen Glucose + 6 O2 (C6H12O6) 6 CO2 + 6 H2O + 36 ATP * more energy and excrete wastes. Phosphorylation: the process of adding a phosphate to a molecule. FOOD + P FOOD – P Phosphorylation FOOD ~ P Food Fragments internal (into the bond) arrangement (lactic acid) ADP ATP Oxidation and Reduction: Oxidation: release energy when a compound loses electrons. Reduction: absorb energy when a compound gains electrons. Hydrogen or Electron Transport: o Hydrogen electrons in hydrogen gas or in organic molecule have a great deal of energy. o Hydrogen electrons in water have low energy. H2 ~ hydrogen is separated 2H+ 2eNAD P + ADP ATP P + ADP FAD ATP ½ O2 3 ATP ADP + P = ATP Cytochrome System H2O Cellular Respiration: Glycolysis: Outside of the mitochrondria ATP ADP Glucose 6C no P add P Glucose – Phosphate 6C1P Fructose - Phosphate 6C1P add p ATP ADP Fructose - Diphoshphate 6C2P 2P + 2ADP 2ATP 2 Phosphoglyceric Acid 2 diphosphoglyceric acid 2 Glyceraldehyde – 2 P (PGA) (PGA) add 2 P (PGAL) 2P 4P 2ATP 2 ADP 3 C 2 P 2H2 2NAD 2 phosphopyruvic acid 2P 6 ATP 2 pyruvic acid (0 P 3 C) Used 4 ATP Gained 10 ATP Net gain of 6 ATP 2NADH2 2ADP 2 ATP Fate of Pyruvic Acid: Without Oxygen: Anaerobic Staircase is incomplete 0 ATP Lactic Acid animals Ethanol plants ~ fermentation Amount of ATP = 6 ATP due to glycolysis With Oxygen: Aerobic Staircase is complete 36 ATP Citric Acid/Krebs Cycle: within mitochondria Uses oxygen and produces carbon dioxide and water The cycle is repeated 2 times. Total ATP produced = 6 + (2 x 12) + 6 (from glycolysis) = 36 Water as a waste Photosynthesis: The process whereby plants store solar energy into organic compounds. 6 CO2 + 12 H2O + solar energy carbon water sunlight dioxide C6H12O6 + 6 O2 + 6 H2O glucose oxygen water Takes place in the chloroplasts of plant cells. o Contains cellulose and cholorphyll which is the pigment that traps sunlight. o Photosynthesis takes place within specialized membranes called thylakiod membranes. o These membranes are stacked one upon another to form stacks known as grana o The fluid surrounding the grana is called stroma. Chemiosmosis: o Different pigments absorb different wavelengths of light that provide the right amount of energy to the electrons within them. Ex: chlorophyll a, chlorophyll b, carotenoid See colours not absorbed by the object (Chloroplasts absorb red and blue) o The trapped energy excites the electrons and boosts them to a higher energy level. Photosystems: Energy capturing phase ~ light dependent The thylakoid membrane appears to have two systems that operate at the same time. High Energy Electron Acceptor Electron Acceptor Electron transport system 3 ATP Electron transport system 3 ATP Photosystem I Pigment Photosystem II Pigment Low Energy 2e- H2O H+ H+ O (lost) Photolysis: splitting of water by light energy NADP Co-enzyme accepts H+ from photolysis NADPH Calvin-Benson Cycle: Carbon fixing phase ~ light independent Occurs in the stroma Light 12 H2O Thylakiod Membrane (Photosystems) ADP, NADP+ 6 O2 ATP, NADPH Light Independent Reactions 6 CO2 6 H2O 3 cycles Glucose Surcose Lipids Proteins Unit 3: Energy and Matter Flow in the Human Body Muscles: Tissue designed to convert chemical energy (ATP) into kinetic energy (movement & heat). Supports body functions Responsible for locomotion (bones), heat production, peristalsis, breathing etc. Types of Muscle Tissue: Smooth Muscle: non-striated, one nucleus, contracts involuntarily, slow and long contracts, don’t fatigue easily, and found along the wall of internal organs. Cardiac Muscle: striated, tubular and branched, one nucleus, contracts involuntarily, found in the walls of the heart. Skeletal Muscle: striated and tubular, contain many nuclei, contracts voluntarily, attached to bones of the skeleton. Functions of Skeletal Muscle: Opposes the force of gravity and enables standing Constant temperature by releasing of metabolic heat is distributed to the body (shivering) Protects internal organs and stabilizes joints: Ligaments hold bones (cartilage in between) together at the joints. Tendons attach muscle to bones Cooperation of Skeletal Muscle: All muscle tissue contracts (shortens) and relaxes (lengthens). Muscles can only pull on a bone when they contract but there must be a force that stretches the muscle after it has stopped contracting and relaxes Flexing causes the bone or limb to move away from its original position. Extension is when the bone or limb moves towards its original position. Muscles are allows in pairs: antagonistic o Bicep causes the arm to flex as the muscle shortens o Triceps causes the arm to extend as the muscle shortens. Hierarchy of Muscle Structure: Muscle (Tendon is heavy tissue that attaches to bone) Muscle-Fibre Bundle (connective tissue surrounds each muscle fibre with nerve and blood vessel running between each bundle of fibres) Muscle Fibre (single muscle cell) o Myoglobin (stores oxygen) o Sarcoplasm (cytoplasm of the muscle fibre, containds myoglobin & glycerine) o Sarcolemma (membrane of the muscle fibre that regulates movement of material) o Sarcoplasmic Reticulum (stores calcium ions) o Myofibrils (cylindrical sub-units that make up a muscle fibre) Myofilaments (protein structures responsible for muscle contractions) Thick Filaments: composed of myosin(heads) Thin Filaments: composed of actin Mechanisms of Muscle Contractions: 1. Myosin head attaches to actin 2. Myosin head flexes, advancing the actin filament 3. Myosin head releases and unflexes, powered by ATP. 4. Myosin reattaches to actin farther along the fibre. Sliding Filament Model of the Sarcomere 1. The heads of the two ends of myosin filament are oriented in opposite directions. When the heads attach to the actin, they bend towards the centre of the myosin. 2. As one end of the myosin filament draws the actin filament and its attached Z line towards the centre, the other end of the myosin filament does the same. 3. Both Z lines move towards the centre, and contraction occurs. Role of Calcium Ions in Muscle Contraction: 1. Muscle is at rest: A long filament, composed of the protein molecule tropomyosin, blocks the myosin binding sites of the actin molecule. Without these sites exposure, muscle contraction will not occur. Calcium ions bond with a molecule called troponin, which results in exposing the myosin binding sites of actin so now muscle contraction can occur. Sequence in Muscle Contraction: 1. Nerve impulse travels to the muscle fibre bundle (stimulus) 2. Ca ions are released from the sarcoplasmic reticulum into the sarcoplasm. 3. Ca ions attach to the troponin (Ca receptor site) thereby causing the tropomyosin to release from the actin. 4. Myosin heads can now attach, release, and reattach using ATP thereby causing muscle contraction (z-lines move together). Sequence in Muscle Relaxation: 1. Nerve impulse stops 2. Ca ions reabsorbed from sarcoplasm into the sarcoplasmic reticulum. 3. Absence of the Ca ions on the troponin allows tropomyosin to reattach to the actin preventing the binding of myosin. 4. Myosin and actin just slide away from each other (z-lines move away). Energy for Muscle Contractions: Stored Energy in a Resting Muscle: 1. Creatine Phosphate is built up and stored in a resting muscle. 2. Glucose and Glycogen is stored in muscle to be used during cellular respiration. Release Energy (make ATP) and Contract the Muscle: 1. Breaks down creatine phosphate, adding the phosphate to ADP to create ATP for immediate use. 2. Carries out anaerobic respiration, by which glucose is broken down to lactic acid and ATP is formed. Lead to fermentation (another way of providing ATP without oxygen which causes cramping and muscle fatigue) Oxygen Debt (replenish creatine phosphate and remove lactate) More in shape a person is the more mitochondria he or she has the less oxygen debt. 3. Carries out aerobic respiration, by which glucose, glycogen, fats and amino acids are broken down in the presence of oxygen to produce ATP. Muscle Contractions or Twitches: Muscles require a stimulus (nerve) to contract, latent period, contraction period (muscle shortens), and a relaxation period (when the muscle returns to its former length). All or none response (one muscle fibre will contract). When there is a short relaxation period, the muscle will fatigue due to a lack of glycogen and excess lactic acid. More stimulus is received, more 100% fibres bundles contract Types of Muscle Twitches: Classified based on how fast the muscle fibres contract. Slow-Twitch: smaller, contract slow, produce energy aerobically, rich in mitochondria, many blood vessels, and are resistant to fatigue (endurance) Fast-Twitch: larger, contract fast, use a lot of ATP, rich in glycogen, low in michondria, less blood vessels, produce energy anaerobically, and fatigue faster (power) Intermediate –Twitch: fast twitch but have a high oxidative capacity. Can increase the proportion of these fibers by training but also heredity. Exercise: Limited by amount of glycogen stored and buildup of lactate. Adaptation to muscles that stores, utilizes, or spares glycogen and removes lactate efficiently improves endurance. Hypertrophy: exercised induced increase in muscle mass Atrophy: reduction in muscle mass o Loss of muscle mass as one ages Disorders of Skeletal Muscles: Technologies to treat muscle condition: Cold: reduces swelling after a tearing Heat: encourages blood flow to healing area (reduces pain and muscle stiffness) Unit 4 Digestion Digestive Processes: 1. Ingestion: taking food into the body (eating). 2. Movement: propels food through the digestive system. 3. Secretion: release of digestive juices in response to a specific stimulus. 4. Digestion: breakdown of food into molecular components through the use of chemical and mechanical means. 5. Absorption: passage of the molecules into the body’s blood stream and movement into the cells. 6. Egestion: removal of undigested food and wastes. Mechanical Digestion verses Chemical Digestion: Mechanical Digestion: molecules stay the same size and the physical motions break big pieces into smaller pieces. Ex: chewing. Chemical Digestion: molecules change and different molecules are produced. Ex: enzyme action. Factors that stimulate ingestion: Habit Hunger caused by low blood glucose levels. Brain stimulation Organs of Digestion: Organs are classified into two groups: Gastrointestinal (GI) Tract: Tube Oral cavity, pharynx, epiglottis, esophagus, stomach, the small and large intestines, appendix, and the rectum/anus. Accessory Structures: Teeth, tongue, salivary glands, liver, gallbladder, and the pancreas. Digestive secretions. Organs of Digestion: Mouth: moistens food with secretions of saliva, grids food which increase the surface area for chemical digestion, and directs the food down the esophagus. Chewing or mastication food creates bolus. Salivary Glands: secrets saliva into food, contains amylase (enzyme) that begins the digestion of starch. Epiglottis: a flap of skin in the pharynx region that closes off the trachea when swallowing food. Esophagus: a large muscular tube that carries food to the stomach. It is made of smooth muscle that contracts in a peristaltic wave motion, pushing the bolus of food along. Peristalsis – squeezing, pushing down Vomiting – reverse wave pushing up Stomach: 1. Provides storage for 1 to 2 litres of material for 3 to 5 hours. 2. Mixes organic juices with a muscular wave-like motion. 3. Starts protein digestion. 4. Sets the rate of digestion between 4 to 24 hours. Liver: Chemistry lab of the body and is the largest gland Produces bile (breaks down fats and neutralizes strong acids) which is stored in the gall bladder. Duel blood supply (poison smasher). Pancreas: Endocrine gland that produces and secretes hormones into the blood stream. (Insulin and Glucagon) Exocrine gland that releases chemicals into the small intestine. Small Intestine: Six meters long. Majority of digestion and absorption occurs in this area. Movement through active transport. Three sections: duodenum (shortest), jejunum, and the ileum (longest) Absorption: Villius Structure: Villi Microvilli Arterial Venous Blood To the liver (HPV) Lymph Fluid Uses active transport so the cells contain a large number of mitochondria. A capillary net supplies the mircovilli with oxygenated blood (arterial) and removes carbon dioxide and organic molecules (amino acids, glucose, fatty acids) through the venous vessels (deoxygenated) toward the liver. Glycerol and more fatty acids are removed via the lacteal vessel that transports the materials to the lymphatic system. Appendix: Stores beneficial bacteria which assists in the digestion of organic material. Large Intestine: Absorbs water, minerals, and salts. 1. Decomposes left-over organic material with the help of resident bacteria (e-coli) which produces vitamin B, K, and Folic acid. Rectum & Anus: Stores feces (undigested cellulose and matter) until it is appropriate to eliminate. Digestion of Carbohydrates Digestion of Lipids Digestion of Proteins Enzyme Summary: Organ Salivary Glands Digestive Secretion Saliva Stomach Gastric Juice Active Digestive Agent Amylase Pepsinogen (+HCL) into Pepsin Rennin Lipase Mucin Liver Bile (gall bladder) Bile Salts Pancreas Pancreatic Juice Sodium Bicarbonate Lipase Amylase Peptidase Small Intestine Intestinal Juice (intestinal glands) Trypsin (active) Chymotrypsin (active) Carbohydrase o o o Mucin Erepsin Maltase Sucrase Lactase Action on Food Breaks down starch into maltose Protein to peptide chains Clots milk lipids into 3 fatty acids and 1 glycerol protective mucus secretion Emulsifies fats Neutralizes acids Neutralizes acids Breaks down fats to fatty acids and glycerol Breaks down starch to maltose Continues the protein breakdown of amino acids. Completes digestion of sugars to glucose. protective mucus secretion Continues the protein breakdown of amino acids. Absorption: Stomach: alcohol and drugs Small Intestine: organic compounds Large Intestine: water, minerals, salts, vitamins How the liver handles excessive material: Glucose is stored in the liver and muscle in the form of glycogen controlled by insulin. Insulin is produced by the pancreas. Glycogen is released by the liver and muscles in the form of glucose controlled by glucagon. Glucagon is produced by the pancreas. Glycerol and fatty acids are converted into lipids and is stored as fat. Amino acids broken down (deamination) into fatty acids that is stored in the liver or in fatty tissue and urea which is excreted via the kidney. Water and minerals are stored in the blood and excess goes through kidneys. Vitamins that are water soluble goes through kidneys and vitamins that are fat soluble are stored in fatty tissue. Glands are stimulated by: Neural control: senses Hormonal control: hormones in the blood Mechanical control or Movement: peristalsis and other movement The hormonal control of digestion: Cholecystokinin (CCK) and Secretin: Trigger: food in the small intestine Produced by: cells lining the duodenum Released into: blood Travels to: gall bladder and pancreas Cause: release of bile to emulsify fat and the release of pancreatic juice (protease, amylase, and lipase) Effect: neutralizes acids and digests fats, starch, and proteins Gastrin: Trigger: presence of undigested food in the stomach Produced by: cells lining the stomach Released into: blood Travels to: gastric glands Cause: release of HCl, pepsinogen, and lipase Effect: digests proteins and lipids Technologies: Endoscope: tube-shaped camera that is inserted into the abdominal cavity. Unit 5: Excretion & Pulmonary Systems Excretion: Location of the Kidney: Renal Abdominal cavity towards the back Right kidney is slightly higher than the left kidney. Diagram of the Urinary System: Role of the Kidney: Remove “waste” Remove any chemical that is present in the blood in amounts greater than the body needs. (water, salt, glucose, etc.) Structure of the Kidney: Nephron: Deamination: Removal of amino group from an organic compound which forms one molecule of urea and one fatty acid. Urea ~ two molecules of ammonia and one molecule of carbon dioxide (less toxic) Uric Acid ~ waste from breakdown of nucleic acid Processes of the Kidney: 1. Force or Glomerular Filtration: Movement of fluids (exception of proteins) from the glomerulus (blood) into the Bowman’s capsule due to blood pressure to become apart of the nephric filtrate. 2. Tubular Reabsorption: Selective transfer of essential solutes back into the blood through active transport. Molecules the body still needs. Proximal tubule, ascending loop of Henle, and distal tubule 3. Tubular Secretion: Movement of wastes from the blood into the nephron through diffusion. 15% of the molecules stay within the nephric filtrate and are removed via the bladder. Proximal tubule, distal tubule 4. Water Reabsorption: Removes water from the filtrate and returns it to the blood. Proximal tubule, descending loop of Henle, distal tubule, and collecting tube. Kidney Reabsorption: Glucose, amino acids, vitamins, and minerals are absorbed by active transport. Change in solute concentration as Cl- is attracted to the + blood causes the tubule to become hypotonic and the blood hypertonic. Hormonal Control of Water Reabsorption: Urine Formation. Hormone: Anti Diuretic Hormone (ADH) Source: Posterior end of the Pituitary Gland Trigger: decreased solute concentration in the blood and osmotic pressure. Released: blood Target: Proximal tubule, descending loop of Henle, distal tubule, and collecting tube. Effect: increased water reabsorption. Hormone: Aldosterone Source: Adrenal Cortex Trigger: increased solute concentration in the blood and osmotic pressure. Released: blood Target: Proximal tubule, ascending loop of Henle, and distal tubule Effect: Reabsorbs Na ions (Na pump) into the blood Kidney Diseases: Diabetes Mellitus: sugar diabetes, body is not producing enough insulin, sugar is not reabsorbed, causing a greater loss of water. Diabetes Insipidus: cannot produce ADH to regulate water reabsorption. Kidney stones: precipitation of mineral solutes in the blood break the kidney tissue. Bright’s disease: protein found in the urine Case Study: Comparing Solutes in Plasma, Nephron, and Urine Micropipettes were used to draw fluids from the Bowman’s capsule, the glomerulus, the loop of Henle, and the collecting duct. Solutes in the fluids were measured. The resulting data are displayed in Table 1. Table 1 Solute Concentrations in Various Parts of the Kidney Solute Bowman’s Glomerulus Loop of Capsule Henle Protein 0 0.8 0 Urea 0.05 0.05 1.50 Glucose 0.10 no data 0 Chloride Ions 0.37 no data no data Ammonia 0.0001 0.0001 0.0001 Substance X 0 9.15 0 Quantities are in g/100ml Technologies: Dialysis: Collecting Duct 0 2.00 0 0.6 0.04 0 Breathing and Gas Exchange: Pulmonary System: Bronchiole Alveoli: Artery Vein * surface area Alveolus (Alveoli) Composition of Air: Compound N2 O2 CO2 High pressure to Low pressure Forces air into the lungs Inhaled Air 78% 21% 0.04% Exhaled Air 78% 16% 5% Breathing Centre: Acidity(low pH) & High Temperature High blood CO 2 No Nerve Impulse Low blood O 2 Breathing Centre Medulla Breathing impulse Muscles Breathing Muscles Relax Elastic Recoil Of Cartilage, Alveoli, & Lung Contraction Nerve Impulse Inhibiting Medulla Decrease in Lung/Chest Volume Increase in Lung Volume Stretch Receptors Decrease Lung Pressure Inhalation Inflated Alveoli Increase in Lung Pressure Exhalation Deflated Alveoli Stops Impulse Removes Inhibition of Medulla Chemoreceptors: send an impulse to the medulla initiating the breathing process. Stretch Receptors: (inflated) inhibit the nerve impulse to the ribs. (deflated) enables chemoreceptors to signal the medulla Breathing Volumes Residual (Dead) Air: air needed to maintain the inflation of the lung Tidal Volume: normal breathing (10%) Inspiratory Reserve Volume: inhale deeply as much as one can Expiratory Reserve Volume: exhale deeply as much as one can Vital Lung Capacity: Tidal, inspiratory, and expiratory reserve volumes. Total Lung Capacity: All capacities together. Case Study: Measuring Respiratory Volumes Patient Tidal Volume (mL) Vital capacity (mL) 1 (normal) 2 3 4 5 500 500 400 550 550 5 000 4 000 3 000 5 000 6 000 Hemoglobin: last from 110 to 120 days Hb (red) carries O2 – 4 sites Hb Breakdown Bilirubin (yellow) Iron Containing Molecule Bile Haem (hem) Globin (protein) Yellow/Brown Feces Kidney Yellow Urine Deficiency Anemia Gas Exchange: Oxygen Deficiency: Short Term: 1. Increased breathing rate and depth 2. Increased heart rate Long Term 1. Increased Hb production (red blood cells). Respiratory rate of patients at rest (breaths/min) 18 20 38 17 17 Unit 6: Circulatory and Immune System: Transport or Circulatory System: Pulmonary Circulatory System: o Carries deoxygenated blood from the heart to the lungs and oxygenated blood back to the heart. Systemic Circulatory System: o Carries oxygenated blood from the heart to the body and deoxygenated blood back to the heart. Blood Vessels: Artery: white color, carry blood away from the heart. o Strong, thick muscular walls, contains three layers. o Has a pulse, carries oxygenated, bright red blood. o Carries blood at high pressure and contains no valves. o Found deep below the surface. Arteriole: tiny vessels that carry oxygenated blood away from the arteries and into the capillaries. Capillary: fluid moves into and out of the capillaries with gases and nutrients. o Thin permeable walls. Venule: move deoxygenated blood back to the veins. o Lower blood pressure because they are further from the heart. Vein: bluish red color, carry blood towards the heart. o Weak, thin non-muscular walls, contains three layers. o No pulse and has low blood pressure. o Contains valves because pressure is low and uses skeletal muscle movement to move blood back up towards the heart. o Found near the surface. Skeletal Muscle Pump: Cardiac or Heart Muscle: Muscle tissue contracts without any nervous impulse (myogenic muscle) and needs to be regulated. Cardiac nodes control and regulate the simultaneous contraction. o Sino-Atrial (S-A) Node: the main regulator or pacemaker of the heart that is able to develop an electrical charge that will cause the atria to contract as a single unit. o Atrial-Ventricular (A-V) Node: tissue that detects the contraction and after a slight pause it develops an electrical charge (depolarization) of its own. RA S-A Node LA A-V Node Bundle of His RV LV Purkinje Fibres Heart Structure: Chambers: Right Atrium: receives blood from the body (deoxygenated) Right Ventricle: sends blood directly to the lungs (deoxygenated) Left Atrium: receives blood from the lungs (oxygenated) Left Ventricle: sends blood to the entire body (oxygenated) Valves: Tricuspid Valve: connects the right ventricle to the right atrium. Prevents blood from flowing back into the atrium when the ventricle contracts. Bicuspid Valve: connects the left ventricle to the left atrium. Prevents blood from flowing back into the atrium when the ventricle contracts. Semi-lunar Valves: prevent the back flow of blood from the arteries to the ventricles. Pulmonary Valve: prevents deoxygenated blood from back flowing from the pulmonary artery to the right ventricle. Aortic Valve: prevents oxygenated blood from back flowing from the aorta to the left ventricle. Septum: divides the right ventricle from the left ventricle. Blood Vessels of the Heart: Coronary Arteries: the blood vessels of the heart, provides oxygen and nutrients to the heart tissue. Pulmonary Artery: carries blood to the lungs for oxygen (deoxygenated). Pulmonary Vein: carries blood to the heart from the lungs (oxygenated). Aorta: the main artery of the body arising from the left ventricle of the heart. Inferior Vena Cava: large vein that leads into the heart with blood from the lower body. Superior Vena Cava: large vein that leads into the heart with blood from the upper body. Pericardium: membranous sac of fluid found around the heart to reduce friction and protect the heart as it works. Major Blood Vessels: Hepatic Portal Vein: blood rich with food material from the intestinal walls traveling to the liver. Hepatic Artery: Hepatic Vein: blood (deoxygenated) the travels from the liver (without food material) back to the heart. Carotid Arteries: left and right in the neck, supplies blood to the neck and brain. Jugular Veins: left and right in the neck, drains blood from the neck and brain. Renal Artery: Renal Vein: Gastroduadenal Artery: connects the hepatic artery to the small intestine. Mechanics of the Heart: Pulse: the movement of the arterial walls due to surges of blood. Vasoconstriction: narrowing of a blood vessel. Less blood goes to the tissues when the arterioles constrict. Caused by low blood volume or increased arteriolar resistance due to plaque or muscle contractions. Vasodilatation: widening of the diameter of the blood vessel. More blood moves to the tissues when the arterioles dilate. Control: Brain * S-A Node Pace Maker Parasympathetic NS Sympathetic NS (Slows) (Speeds) Atria A-V Node (delays impulse) Ventricles Spinal Cord Mechanics: 1. Atrium relaxed (diastole) and fills with blood from the S.V.C. and I.V.C. 2. Atrium contracts (systole) and forces blood through the A-V valves into the ventricle which is relaxed (diastole). 3. Ventricle contracts (systole). Blood tries to escape to the atrium (back flow) but gets caught in the valve flaps causing the A-V valves to snap shut. (1st heart beat ~ lub). Blood is now forced out the pulmonary artery or aorta opening the semi-lunar valves which causes the arteries to stretch. 4. Ventricle relaxes (diastole). Blood pressure decreases and blood attempts to back flow because of gravity and the elastic recoil or the arteries. This blood gets caught in the semi-lunar valves which snap shut. (2nd heart beat ~ dub). Electrocardiograph: Measures the electrical activity of the heart. Systolic Pressure (heart contracts) Diastolic Pressure Heart relaxes Blood Pressure and Capillary Exchange Blood pressure is necessary for circulation and fluctuates within normal ranges. Measured in the arteries Factors involved with Blood Pressure: Blood Volume: amount of blood. Hemorrhaging (blood loss) can cause a drop in blood pressure. Heart Rate and Force Arteriolar Resistance: vasoconstriction increased blood pressure vasodilatation decreased blood pressure Control of Blood Pressure: o Blood pressure sensed by baroreceptors or stretch receptors found in the aorta and carotid arteries sends messages to the medulla oblongata. o Osmotic Pressure: pressure exerted on the wall of a semi permeable membrane resulting from differences in solute concentration sends information to hypothalamus. Sphygmomanometer: measures blood pressure using mm Mercury (mm Hg) Ex: 120 / 70 mm Hg Cardiac Output: Humans have about 5 L of blood in an adult Cardiac Output: the amount of blood pumped from the heart each minute. o Cardiac output = stroke volume X heart rate Stroke Volume: the quantity of blood pumped with each beat of the heart. o Most individuals pump about 70 ml of blood per beat while resting. o Stronger hearts pump more which results in lower heart rates. CO = SV x HR 5 L = 50ml/beat x 100 beats/minute Heart Diseases or Disorders: Technologies: CT scan CAT scan MRI scan Angioplasty Components of Blood: Whole Blood Plasma (Liquid) 55% *cannot pass through a capillary Proteins ~ Albumins & Globulins (antibodies) Smaller Proteins ~ Insulin Organic Molecules (G, AA, FA) Glycerol, Vitamins Urea Mineral Salts Water Mineral Ions *can pass through a capillary Cell Component Bone Marrow ~ Stem Cells Erythrocytes Red Blood Cells Hemoglobin which transports O2 45% Leucocytes (Leukocytes) White Blood Cells Larger / Less than RBC Immunity Cells - engulf organisms - produce antibodies <1% Platelets (Thrombocytes) Very small and rare Blood Clotting Blood Types: ABO Antigen: proteins found on cells ~ identification marker Antibody: proteins found in plasma that react with specific antigens RBC Antigen A Blood Type Antibody Potential Whom it can be Donated Whom it can be Received A Anti B A, AB A, O Anti A B, AB B, O - AB A, B, O, AB nd 2 most common B rd B 3 most common A&B AB Universal Recipient Least common - A, B, AB, & O O Universal Donor Sensitized Blood: blood has developed antibody potential For Compatible Transfusions: must match donor’s antigen with recipient’s antibodies Agglutination: clumping of blood caused by the antibodies attacking the antigens. Rhesus Factor: Rh -/+ Antigen RBC R Most common O Anti A and B Blood Type Antibody Potential Whom it can be donated Whom it can be received Rh + - Rh + Rh + & Rh - Anti R Rh + & Rh - Rh - Most common - Blue Baby Syndrome: Rh - Lymphatic System Collects the excess fluid and proteins that causes swelling in the tissues (edema). Fluid and proteins are returned to the circulatory system by way of the lymphatic system. Lymph Nodes: enlargements located at intervals along the lymph vessel that house lymphocytes (white blood cells). ~ swell when sick. Fluid moves as a result of osmotic pressure, gravity, and absorption. Lymph node Lymph Vessel The Immune System: A system of non-specific and specific defence mechanisms. Lines of Defence: 1. Skin and Mucus Membranes: (barriers) Oil, sweat, mucus, and tears contain chemicals that kill or capture bacteria. 2. Non-specific Defence (Cell-Mediated Immunity): White Blood Cells: Macrophages, neutrophils, & monocytes o Phagocytes (neutrophils & Monocytes) eat other cells or objects found in the body using phagocytosis. o Natural Killer Cells target the body’s own infected cells or that have become cancerous. Inflammatory Response: o Damaged tissue release histamine which cause blood to flow to the area (swelling and pus formation) and could cause the body to raise its temperature. Allergies: overreaction to harmless cells. 3. Specific Defence (Antibody-Mediated Immunity): Immune Response: a recognization system that distinguishes “self” from “non-self”. Production of antibodies that circulated around the body in blood and lymph fluid. Protects against bacteria and viruses. Cells destroy host cells infected by protozoans, fungi, bacteria, and viruses as well as cancer cells and foreign tissues. B Cells (from bone marrow) ~ produce antibodies T Cells (from thymus gland) Immunological Memory: enables a quick response to reinfection by the same antigen. Vaccines: adding a weakened version of the antigen to the body so that it develops antibodies and a memory to combat it in the future. Unit 7: Energy and Matter Exchange in the Biosphere Biosphere: Stable environment in which nonliving and living things interact and in which minerals are recycled and energy flows in and out. Closed System: System is self-contained Nothing is needed from an outside source ~ raw materials or waste removal. Abiotic and Biotic components Abiotic or Nonliving Components ~ chemical, geological, or physical factors. Ex: soil, minerals, temperature, water, energy, and atmosphere. Biotic or Living Components ~ life forms Biotic Influences in the Biosphere: Solar energy powers the cycling of biochemical matter trapped and release in living organisms. Input energy solar energy Biochemical Cycles Output Energy heat The Biogeochemical Cycles: 1. Hydrological Cycle: As water travels through the biotic and abiotic components of the biosphere, it carries much material with it, including chemical nutrients. This links the hydrologic cycle with the biogeochemical cycles, through which nutrients travel. Large specific heat capacity holds and releases a great deal of heat. Hydrological cycle connects ecosystems together Metabolic reactions take place within water. Supply of hydrogen and oxygen 1. 2. 3. 4. 5. 6. 7. evaporation condensation precipitation infiltration runoff (percolation) transpiration storage (in atmosphere, ice and snow, freshwater bodies, and oceans) 2. The Carbon Oxygen Cycle: Biotic component ~ complementary processes of photosynthesis and cellular respiration. Decomposers release organic material back into carbon dioxide. Abiotic component ~ carbon dioxide is mostly stored as carbonic acid in water and the release via volcanic eruptions Disruption by human activity ~ release of stored organic (deforestation) and inorganic (fossil fuels) carbon. ~ greenhouse effect 3. The Nitrogen Cycle: The nitrogen cycle is a biogeochemical cycle that shows how nitrogen is converted into different forms as it is transported through the air, water, and soil. All organisms require nitrogen to make proteins and genetic material (DNA). Nitrogen in the Air: Nitrogen gas (N2) makes up 78.1 percent of Earth’s atmosphere by volume. Most organisms, however, cannot use atmospheric nitrogen. Nitrogen in the Water: Nitrogen gas is removed from the atmosphere via nitrogen-fixing cyanobacteria, which convert it into a form plants can use— ammonium (NH4+). Some types of aquatic bacteria then convert the ammonium into nitrate (NO3), which plants can also use. Nitrogen in the Soil: Nitrogen fixation or Nitrification is the conversion of nitrogen gas (N2) into nitrates (NO3-) and ammonium ions (NH4+), which then can be used by plants. Nitrogen-Fixing bacteria convert atmospheric nitrogen to nitrates Ammonification ~ process where nitrogen is released from decaying protein as ammonia. Other bacteria convert nitrate back into nitrogen gas via denitrification. Lightening causes nitrogen to react with oxygen to produce nitrates to be dissolved in the soil solution. 4. The Phosphorous Cycle: The phosphorus cycle is a biogeochemical cycle that shows how phosphorus is converted into different forms as it is transported through the water and soil. All organisms require phosphorus as a part of cellular DNA and ATP (the energy carrier essential to all cells). Phosphorus in the Air: Unlike carbon, nitrogen, and sulfur, phosphorus does not cycle through the atmosphere. Phosphorus in the Soil: Weathering gradually releases phosphorus trapped in rocks and makes it available to organisms. Plants and algae can only use phosphorus in the form of phosphate (PO 43). Phosphorus is scarce in the environment. This keeps the growth of producers in balance, but it can also limit the growth of crops. Phosphorus in the Water: The growth of algae in aquatic ecosystems is limited by the amount of available nutrients. Because it is scarce in the environment, excess phosphorus in aquatic ecosystems can result in algal overgrowth, known as an algal bloom. 5. The Sulfur Cycle: The sulfur cycle is a biogeochemical cycle that shows how sulfur is converted into different forms as it is transported through the air, water, and soil. All organisms require sulfur as an important component of proteins and vitamins. Sulfur in the Air: The decomposition of organic matter, volcanic offgassing, and human activities all release sulfur into the atmosphere. Rain and snow soon return sulfur to Earth’s surface via acid deposition. Sulfur in the Water: Plants and algae take up sulfur in the water-soluble form of sulfate (SO42). Sulfur in the Soil: Decomposers quickly return sulfur to the soil or air as hydrogen sulfide (H2S). Soil bacteria use sulfur compounds in photosynthesis or cellular respiration, thus playing an essential role as they convert one form of sulfur to another. Some sulfur is taken out of rapid cycling when bacteria convert sulfur to forms that are layered down as sediments, eventually becoming part of rocks. Ecology: The study of the flow of energy and matter through an environmental system. Open System: System is depended upon an outside source ~ influx and removal of materials. Ex: human cells, ecosystems etc. Dynamic Equilibrium or Homeostasis: All parts of a system must adjust to any change made by one component to keep balance. Ecosystems: Semi-closed system where matter is recycled between abiotic and biotic components. Driven by energy driven ~ eventually lost. ~ open system The Laws of Thermodynamics: 1. Energy cannot be created nor destroyed, only transformed from one form to another. Energy Input = Energy Output 2. During an energy transformation, some of the energy produced (heat) is lost from the system. Energy Input = Energy Output + Waste Energy (Heat) All organisms need: Organic molecules and energy Energy Flow in the Ecosystem: Autotrophs ~ Self-Feeder, organisms capable of obtaining their energy and matter from the physical environment. Producers: photosynthesis or chemosynthesis ~ formation of carbohydrates from chemical energy and not light energy. Ex: nitrogenfixing bacteria Heterotrophs ~ organisms that obtain food and energy from autotrophs or other heterotrophs. Consumers: organisms that break down living tissue. Primary: herbivores (organisms that only eat producers) Secondary: omnivores (organisms that eat producers and primary consumers) Tertiary: omnivores and carnivores (organisms that only eat consumers) Decomposers ~ bacteria and fungus that break down the remains or waste of other organisms to obtain their organic nutrients. Trophic Levels: Locates the position of an organism during its energy – seeking activities. The number of energy transfers an organism is form the original solar energy entering the system. Food Chain: rule of 10 !00% 0.001% Sun Top 10% 1% 0.1% Plant Grasshopper Bird Producer Primary Consumer st 1 Trophic nd 2 Trophic Level Herbivore Snake Secondary rd 3 Trophic Carnivore 0.01% Owl Tertiary Quaternary or th 4 Trophic 5 Th Trophic Food Webs: A series of interlocking food chains representing the transfer of energy through various trophic levels in an ecosystem. th 4 Consumer Sun nd 2 Consumer st 1 Consumer Producers Decomposers Heat Types of Ecosystems: 1. Terrestrial Ecosystems: Classified into major types called biomes. Each biome has a distinctive climate (water and heat), plant and animal life. Tundra: arctic, short growing season, permafrost, low precipitation, seals, lichen, caribou. Boreal Forest: south of tundra, wet & acidic soil, more precipitation, spruce, moose. Mixed Deciduous Woodland Forest: rich fertile soil, most precipitation, maple, weasels, woodpeckers. Grassland: less precipitation, soil holds less water, hawks, rattlesnakes, bison. 2. Aquatic Communities: High specific heat capacity and the high thermal conductance (rate at which heat passes through water) of water allows a much more stable temperature than in the terrestrial ecosystem. Divided into two categories depending upon the amount of salt dissolved in the water (salinity); Freshwater and Saltwater. Marine Communities: More diverse than freshwater communities. Divide it into zones based upon water depth. Freshwater Communities: Lakes have three layers: Littoral region: light can reach the bottom resulting in a large community of producers and consumers. Limnetic region: open water that allows for photosynthesis but doesn’t allow rooted plants to exist. Profundal region; Insufficient light for photosynthesis and contains only scavengers. Littoral Limnetic Profundal Ecological Pyramids: Represent energy flow in food chains and webs. Based on the idea that energy is lost at each trophic level. Energy lost due to heat, activity, growth, and reproduction. 1. Pyramid of Numbers: Energy pyramid based on the numbers of organisms in each trophic level. th 1 4 consumer rd 75 3 consumer nd 500 2 consumers st 50 000 1 consumers 100 000 producers st Sometimes a pyramid of numbers can be inverted because many 1 consumers can live on one producer. 2. Pyramid of Biomass: Energy pyramid based on the dry mass of tissue of the organisms at each trophic level. Measured in kg 25kg 500kg 12 000kg 200 000kg 3. Pyramid of Energy: Energy pyramid based on the amount of thermal (heat) energy produced at each trophic level. Measured in KJ/m²/year 100 1 000 15 000 100 000 20 000 Factors Interfering with Ecological Pyramids: Seasons ~ decreased amount of solar radiation in winter months changes the number of producers. Natural Changes ~ retreating glaciers, floods, volcanic eruptions, earthquakes, and fires. Human-Induced Changes ~ Fires, flooding due to dams, pollution, hunting and fishing, monocultures ( growing a single plant species to the exclusion of others), and pesticides (DDT and Peregrine falcon). Biological Amplification: The buildup of toxic chemicals in organism as tissues containing the chemical move through the food chain. Scientific Explanations for Changes in Atmospheric Conditions: Beginning: anoxic environment (no oxygen) Big Bang which released radiation, particles, and clouds of atoms creating stars. New stars (SUN), with the help of gravity, created planets. Soon life appeared on Earth in the form of primitive single cell photosynthetic organisms. Middle: Evolution was played out the same time the continents were drifting. Single cell organisms with nuclei appeared e.g.; algae (plants) and protozoa (animals) Organisms began to live together in colonies resulting in invertebrate animals and more complex algae. Plants moved onto land and followed by animals. Current: (Biosphere Equilibrium) Atmosphere is composed of solid particles, water vapour, and atmospheric gases: Greenhouse Effect: Carbon Dioxide absorbs the heat and acts as a heat trap and results in the warming of the Earth’s temperature. Human activity has caused an influx of carbon dioxide. Ozone Layer: Contains the ozone layer absorbing ultraviolet radiation (O2 ~~> O3) Depletion is the result of the release of Chloroflurocarbons (CFCs), which are broken down by UV light allowing chlorine molecules to combine and trap thousands of ozone molecules. Unit 8 Ecosystems and Population Change Organizational Levels of the Biosphere: Organism: one individual (single or multicellular) Population: group of individuals of the same species located in a particular area. Species: individuals which are genetically similar enough to produce viable and fertile offspring. Sexual reproduction at this level allows for variation and genetic recombination. Variation is any genetic, behavioural, and physical difference between individuals in a population or between parents and offspring, allows for the continuation of the species in changing environments, and is source of new adaptations (mutations). Community: many populations interacting together as they coexist in the same area. Ecosystem: biotic (living) and abiotic (non-living) characteristics combine and interact together. Biotic Components: community (living factors) Abiotic Components: chemical, geological, or physical factors (environment) that influence living organisms. Biosphere: many ecosystems (terrestrial and aquatic) interacting together Biogeochemical and Hydrological Cycles connect the ecosystems together. Taxonomy: Classification of Living Things (Domains, Kingdoms, Phyla, Classes, Order, Family, Genus, Species) Three Domains Bacteria: prokaryote, unicellular organisms, lack a membrane-bound nucleus, reproduce asexually, heterotrophic by absorption, autotrophic by chemosynthesis or photosynthesis, move by flagella. Archaea: prokaryote, unicellular organisms, lack a membrane-bound nucleus, reproduces asexually, many are autotrophic by chemosynthesis, unique rRNA sequence, distinctive cell membrane. Eukarya: eukaryotic, unicellular to multicellular organisms, membranebounded nucleus, sexual reproduction, nutrition diverse. Six Kingdoms: Archaea: single celled, prokaryote cells living in extreme environments. Bacteria: single celled, prokaryote cells living in a wide range of habitats. Protista: unicellular and multicellular organisms that are eurkaryote (autotrophs and heterotrophs). Fungi: obtain food by digesting and absorbing food outside of their tissues, sessile, no chloroplasts. Plantea: photosynthesizers, sessile, contain chloroplasts Animalia: consumers (decomposers) that move and ingest food Binomial Nomenclature: Linnaeus used Latin and Greek terminology to name organisms (universal understanding) Genus and Species Dichotomous Keys: Identification key that uses series of paired comparisons to sort organism into smaller and smaller group. Climate and Biomes Climate: average weather conditions (temperature and rainfall) in a particular region over a period of time affected by unequal heating of the earth (sphere), snow and ice cover, proximity to water, local geography, currents, and seasons (tilt). Biomes: terrestrial ecosystems types that are directly affected by climate. (Ex: taiga, tundra, desert, etc.) o Mix of plants and animals that are adapted to living under these climate conditions. Habitat: The environment in which an organism survives. Limited by climate, water, soil conditions, and vegetation. Geographic Range: o The total area, extent of locations of habitat, where and organism may live naturally. Ecological Niche: o An organism’s profession, role, trophic level or feeding level o It is the total environment and way of life of all the members of a particular species in the ecosystem o Involves factors like feeding habits, number of offspring per birth, interspecies (different species) relationships, effect on soil, etc. o E.g. producer/consumer/decomposer, predator, prey, parasite. Limiting Factors: Components of an ecosystem that can limit or restrict the number of individuals within a population. They can influence an organism distribution and range. Abiotic Limiting Factors: o Non-living components or requirements like soil type, moisture, humidity, temperature, altitude, pH levels etc. that can influence the growth of plants and thus, animals. Biotic Limiting Factors: o Populations can grow fast when more births occur than deaths o Populations can level off and be constant if births roughly equal deaths o Populations can also drop or die off if there are more deaths than births. o Determined by: Competition for Resources: food, space, water, niche, mates Intraspecific competition for resources among members of the same species Interspecific competition for resources among populations Predators: Predator consumes prey (deer eating grass or wolf eating deer) More prey, more predators etc. Parasites: Parasite derives nourishment from a host that is harmed by the relationship. More hosts, more parasites Sampling Population Size and Density: By sampling a portion of the population one can get an estimate of the whole population size. Biologist use transects and quadrates to calculate density which is used to estimate the size of populations. Random locations. Transects are long, narrow, rectangular area marked out in a study area where one counts all the individuals of each species. (5m x 100m) Quadrates are square areas used to count the individuals of one species. (1m x 1m). Density: the number of individuals per unit of volume or area. Environmental Changes: Organisms are adapted to their environment and when there is a change in those environmental conditions they have to do one of three things: 1. Migrate to a more suitable environment. E.g. birds, seeds. 2. Die out as a species. 3. Adapt as a species or Evolution Evolution: Cumulative changes in characteristics of populations of organism in successive generations. Environment exerts selective pressure on the population not the individual. Certain characteristics are better suited for the environmental conditions are selected for and ones that are not are selected against. Adaptation: An inherited trait or set of traits that improve the chances of survival and ultimately lead to a greater chance of reproducing. ~ genes or DNA Variation in traits can provide a population with flexibility if the environmental conditions change. Selective Advantage: characteristic that improves an organism’s chances of survival in a changing environment as a result of a mutation. Ex: ground squirrel blood factor that combats rattlesnake venom Types of Adaptations: Structural: The most obvious adaptation. Involves modifications to the organisms’ body shape or parts. Functional like ducks have webbed feet for swimming. Deceptive like camouflage Warning coloration: bright colors and patterns to warn other organism like a bee Mimicry: color pattern or body shape which resembles a harmful or distasteful organism. Physiological: Involves the chemical processes organisms use to survive and be successful in their environment. Enzymes: special protein structures that control body functions like temperature, digestion, muscle contraction, etc. Example: snake venom Pheromones: chemicals secreted by organisms to influence the behaviour of another organism of the same species. Example: line of ants Behavioural: Quickest adaptation to environmental change. Involves a behavioural response to a specific stimulus. Hibernation, migration, hunting, reproductive rituals, attraction to light. Ex: dogs, plants, people. Evolution of the Theory of Natural Selection: Leading theory behind the mechanisms of evolution 1. Buffon’s Histoire Naturelle: Suggested that the earth was older than 6000 years. Noted similarities between humans and apes and suggested that they might have a common ancestor. 2. Cuvier’s Fossils: Developed the science of paleontology which studies ancient life by looking at fossils and the residue of geological changes in time (volcanoes etc.) Oldest fossils are in deeper layers. 3. Lyell’s Principle of Geology: Geological changes and processes operate at the same rate now ands they did in the past. (Biblical stories ???) 4. Lamarck’s Theory of Evolution: 1801 One attempt to explain evolution had three parts: 1. The Theory of Need: Organisms produce new organs or parts as they need them. Ex: ancestor of snakes had a short body and legs but as the land changed it became necessary for them to stretch into narrow spaces. 2. The Theory of Use and Disuse: Organs and parts only remain healthy and strong as long as they are used and disappear when they are no longer used. Ex: snake’s legs disappeared because the snake didn’t use them anymore. 3. The Theory of the Inheritance of Acquired Characteristics: All the changes that an organism makes in life are passed onto its offspring. Ex: snakes whom lost their legs in life would produce legless offspring. 5. Charles Darwin and Alfred Wallace’s Theory of Natural Selection: 1859 1. Overproduction: All organisms produce more offspring than can survive. Ex: Fish 2. Struggle for Existence: (Competition) Due to this overproduction, organisms constantly struggle for existence. Ex: My brother the hamburger 3. Individual Variation: Individuals within a species will vary. Genes the basis of natural selection. 4. Survival of the Fittest: The best adapted, or fittest, individuals will survive. Organisms, which survive, will pass the variations onto their offspring. 5. Origin of New Species: Over numerous generations, new species arise by the accumulation of inherited variations. Species becomes a group of organisms which normally interbreed in nature to produce fertile offspring. Speciation: the formation of a new species.. 1. Transformation: a new species gradually develops as a result of mutation and adaptation to changing environmental conditions and the old species is replaced. Ex: ancestral mammoths to steppe mammoths to wooly mammoths. 2. Divergence: one or more species, with different characteristics adapted to different environmental factors, arise from a parent species that continues to exist. Ex: Ancient bear evolved into polar bear, grizzle bear, and brown bear. Isolation or Barriers that Lead to Divergence: Geographic Isolation: A part of a population becomes isolated by the environment causing the changes to the amount of variation found in the gene pool. Adaptive Radiation: evolution of many new species from a common ancestor in new environments. New species fit into different niches and are then adapted to that different environment but from the same ancestor ex: finches found on many islands. Reproductive Isolation: Any resulting barrier to interbreeding which limits variation and produces new species. Ex: dogs Pace of Evolution: Gradualism: changes in populations occur in a steady, linear fashion where change is consistent. (Contradicted by fossil record) Punctuated Equilibrium: long periods of equilibrium where there is little change and then is interrupted by periods of speciation. Evidence for Evolution: 1. Fossil Record: Skeletal remains preserved as fossils documents the gradual change that has occurred among species. Fossils are formed in sedimentary rock and deposited in layers. Many extinct organisms documented in deeper layers. Fossils provide direct evidence of the pathways taken by living organisms in their evolutionary history or phylogeny. Older organisms are less complex than newer ones. The number of early forms of organisms was small. Gaps in the record prevent a complete pathway of evolution. 2. Biogeography: Distribution patterns of organisms have been affected by geographical events: Theory of Plate Tectonics: The earth’s plates are constantly moving and have caused the continents to drift apart. Separated and isolated species. Climate: Different climates have caused different species to evolve in order for them to survive the environment. Convergent Evolution: the process by which distantly related organisms develop similar characteristics as a result of being subjected to similar environmental pressures. Ex: dolphin, salmon, whale Ex: Australia, marsupial animals evolved. 3. Embryology: The development of the embryo is similar for all vertebrates which suggests a relationship between species or that they all evolved from the same ancestor. 4. Physiological Evidence: Vestigial Organs: seemingly useless organs that are also found in related species. Remnants of structures in ancestors that are no longer selected for. A contradiction to Lamarck’s Theories. Ex: Human appendix or tailbone. Similar physiology can also indicate a relationship between two species. Ex: kidney waste in birds is similar to that of reptiles. Ex: hormones from sheep and pigs can be injected into humans ~ insulin. 5. Biochemical Evidence: Similar molecules that make up different living things suggest relationships. DNA analysis, humans share 98% of the same genetic information as chimpanzees. Amino acid sequencing. 6. Homologous and Analogous Structures: Homologous Structures: similar origins but difference uses in different species. Ex; front flipper of a dolphin and front paw of a dog. Indicate similarities in ancestry. Analogous Structures: similar in function and appearance but not in origin. Ex. Wing of a bird and insect.