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15.3 PDQ 1. Fill out the chart Hardy Weinberg Equations P + Q =1 P2 + 2PQ + Q2 = 1 Required Conditions for HW Equilibruim No net mutations No natural selection No gene flow Large population size Random Mating 2. What is the significance of the HW equilibrium? • It allows us to see if evolution is occurring in a population 3. • 1 If all of the above conditions hold, how many generations are required for a population to reach HW equilibrium? 4. What do deviations from HW equilibrium indicate? • That evolution is occurring! 5. p. 299 A. Calculate the allele and genotype frequencies of Ldh in this newly founded population? Allele frequency of A = 10/20 = 0.5 = p Allele frequency of a = 10/20 = 0.5 = q AA Genotype frequency = 4/10 = 0.4 = P2 Aa Genotype frequency = 2/10 = 0.2 = 2pq aa Genotype frequency = 4/10 = 0.4 = q2 5. p. 299 #b • No because P2 does not equal 0.4, it equals 0.25. and Q2 does not equal 0.2, it equals 0.25. 5. #c • Same Allele frequencies: p = 0.5, q = 0.5 (unchanged) Genotype frequencies: Frequency of aa = p2 = 0.25 Frequency of Aa = 2pq = 0.5 Frequency of AA = q2 = 0.25 • #5 d • Small population (only 10) • Gene flow could occur (it happened before due to the hurricane!) • Random mating is not possible • Selection for or against a trait could occur Summarize the effect of the following on allele frequencies Mutations If dominant mutation, p goes up; If recessive mutation, p goes down etc. Gene Flow Emmigration would lower p and q; Immigration would increase p and q Genetic Drift Random – p and q would change either way Non-Random mating Chosen traits (dominant or recessive) would go up Natural Selection Best fit traits for survival (dominant or recessive) would go up