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2015-04-01 LightandMatter Rayleigh Scattering_Phase Function MD6305Laser‐TissueInteractions Class4 JaeGwan Kim [email protected] ,X2220 DepartmentofMedicalSystemEngineering Gwangju InstituteofSciencesandTechnology Copyright.Mostfigures/tables/textsinthislecturearefromthetextbook“Laser‐Tissue InteractionsbyMarkolf H.Niemz 2007”andthismaterialisonlyforthosewhotakethis classandcannotbedistributedtoanyonewithoutthepermissionfromthelecturer. ModelsofLightScattering whereπDp isthecircumferenceofa particle andλisthewavelengthofincidentradiation • α<<1:Rayleighscattering(smallparticlecompared towavelengthoflight,I1/λ4) • α≈1:Miescattering(particleaboutthesamesizeas wavelengthoflight) • α>>1:Geometricscattering(particlemuchlarger thanwavelengthoflight) 1 2015-04-01 RayleighScattering • Rayleighscatteringreferstothescatteringoflight offofthemoleculesoftheair,andcanbeextendedto scatteringfromparticlesuptoaboutatenthofthe wavelengthofthelight MieScattering • Forparticlesizeslargerthanawavelength,Mie scatteringpredominates.Thisscatteringproducesa patternlikeanantennalobe,withasharperand moreintenseforwardlobeforlargerparticles. 2 2015-04-01 Rayleighvs MieScattering Rayleigh’sLawofScattering 3 2015-04-01 RayleighScattering • Rayleighscatteringiselasticscattering same valuesofk andλ asincidentlight 1. WeneglectedabsorptionduringtheRayleighlaw derivation 2. Wealsodidnotconsiderthespatialextentof scatteringparticles(Rayleighonlyworksforthe particleswhichhasmuchsmallersizethanthe wavelength) needtoapplyMiescatteringtheory RayleighvsMieScattering • Theyaredifferentintwoimportantrespects 1. Miescatteringshowsaweakerdependenceon wavelength(~ with0.4 0.5)whileRayleigh scattering(~ ) 2. Miescatteringmostlyoccursintheforwarddirection, whereasRayleighscatteringis~1 forward andbackwardscatteredintensitiesarethesame 4 2015-04-01 Brillouin Scattering • Brillouin scattering:inelasticscattering – Arisesfromacousticwavespropagatingthrougha mediumandthuscausesinhomogeneities oftheR.I. – Itcanhaveeitherhigherorlowerfrequenciesbecause scatteringparticlesaremovingtoward(orawayfrom)the lightsource consideredasanopticalDoppler effect – Thisbecomesimportantonlyduringthegenerationof shockwaves Léon Nicolas Brillouin (French: [bʁilwɛ̃], bree‐u‐we(n)); August 7, 1889 – October 4, 1969) was a French physicist. He made contributions to quantum mechanics, radio wave propagation in the atmosphere, solid state physics, and information theory. However,inRealTissue… • Photonsaremostlyforwardscattering(Rayleighscattering cannotbeapplied) • WavelengthdependencyisstrongerthanpredictedbyMie theory • Thus,neitherRayleighnorMietheorycompletelydescribe scatteringintissues • Definingaprobabilityfunction p(θ)ofaphotontobe scatteredbyanangleθ isconvenienttofitwithexperimental data • , :phasefunctionofaphotontobescatteredfrom direction into , • Ifp(θ)isnotdependentonθ isotropicscattering, otherwise,anisotropicscatteringoccurs 5 2015-04-01 ProbabilityFunction • Coefficientofanisotropyg isdefinedby Arc length cos where sin isaprobabilityfunctionand istheelementarysolidangle. • Bydefinition,g representstheaveragevalueofcos cos • g rangesfrom0.7~0.99inbiologicaltissues 8o~45o isalsocalledasphasefunction. • PhaseFunction • Phasefunctionisnormalizedby 1 4 1 – Since theprobabilityofphotonscatteredintosomewherewithin4 steradianis1,theintegralof in4 is4 . • Severaltheoreticalphasefunction – – – – proposed Henyey‐Greensteinfunction Rayleigh‐Gans function δ‐Eddington function Reynoldsfunction ’ • Amongthese,Henyey‐Greensteinfunctionisthebestfitwith theexperimentalobservations 6 2015-04-01 Henyey‐GreensteinFunction • ThiswasintroducedbyHenyey andGreenstein(1941)andisgivenby 1 1 4 1 2 cos / • Itiscommonpracticetoexpressasthefunction cos 1 1 2 1 2 cos / • Thisismathematicallyveryconvenienttohandlebecauseitisequivalent to cos where • 2 1 cos aretheLegendrepolynomials ! 1 ,∑ ModifiedHenyey‐GreensteinFunction • Insomecase,acompositefunctionofanisotropictermu and theHenyey‐Greensteinfunctionfitbettertoexperimental data. • Themodifiedfunctionisgivenby 1 1 1 4 1 2 cos / 7 2015-04-01 Henyey‐GreensteinFunction • Itdescribesthedominantprocessofscatteringin theforwarddirectionverywell • Fig.2.9describesanexperimentaldataforan80μm sampleofaortictissue TurbidMedia • Sofar,weconsideredtheoccurrenceofeitheronly absorptionorscattering • Inmosttissues,bothofthemarepresent turbid media • Totalattenuationcoefficient • Themeanfreepathofturbidmediais 1 1 8 2015-04-01 OpticalAlbedo • Itisveryconvenienttodefinetheopticalalbedoby • Whena=0,attenuationisexclusivelyduetoabsorption, whereasa=1,attenuationisonlyfromscattering OpticalDepth • Inturbidmedia,definingopticaldepthd isgivenby where denotesthesegmentofopticalpathands isthetotallengthofopticalpath • Whenthemediumishomogeneous,i.e. is constant, 9 2015-04-01 Advantageofaandd • Insteadof and ,aanddaredimensionless parameters • However,aanddcontainssameinformationas and • Inturbidmedia,thenormalizationofthephase functionshouldbealteredto ,(0 • • 1) / cos ∑ 2n 1 cos Reduced ScatteringCoefficient • Reducedscatteringcoefficientisveryusefulwhen discussingthediffusionapproximationandisgiven as 1 • Sinceforwardscatteringalonewillnotcause attenuationofintensity,thereducedtotal attenuationcoefficientisgivenby 10