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Names (two only!) Create a poster that accomplishes the following learning objectives: Date Period Compare the structure of RNA and DNA. Outline (illustrate) DNA transcription in terms of the formation of an RNA strand complementary to the DNA strand by RNA polymerase. Describe (with an illustration) the genetic code in terms of codons composed of triplets of bases. Explain (using models) the processes of transcription and translation, leading to polypeptide formation. Modeling Transcription: Your assignment: Use your DNA and two other colors of construction paper (one for uracil and one for ribose) to construct a transcribed model of mRNA that is complimentary to one strand of your DNA molecule. Use those models as a basis to illustrate a poster that shows transcription of mRNA. Your transcribed mRNA must code for a polypeptide that is at least four amino acids long. It must begin with a proper initiation codon and end with a proper STOP codon. You poster must include labeled: • DNA •mRNA, •RNA plymerase You need to clearly label and identify (you may use a key or legend) the following: •the components of DNA, mRNA (sugar, phosphate, nitrogenous base, base pairing) •differences between DNA and RNA •processes of transcription including where in the cell they take place •correct representation of all base pairing (A-T, A-U, G-C) •a strand of mRNA coded from at least four codons, beginning with the proper initiation codon and ending with a STOP codon. Models of DNA, mRNA must be models attached to the paper, not simply drawn on the poster. Modeling Translation: Your assignment: Complete your poster with an illustration of the process of translation. You poster must include labeled: • tRNA (with attached amino acid) •Ribosome •Growing polypeptide chain Models of DNA, mRNA, tRNA and growing amino acid chain must be models attached to the paper, not simply drawn on the poster. For full credit, base pairing must be accurate throughout the entire poster. For full credit, you must demonstrate your understanding of the genetic code by illustrating the correct codon and anticodon sequences for initiation, all amino acids shown, and the stop codon. Your Name(s) Only one name for construction project. One or two names for performance project. Today’s Date URL Extra Credit Construction Opportunity (one student per construction project) •Option 1: Construct a 3 dimensional DNA model, clearly labeling deoxyribose, phosphate group, 4 different nitrogenous bases, base pairing, and a nucleotide. Label the 5’ and 3’ ends and clearly illustrate that the two strands are antiparallel. 10 points awarded into an optional 10 point test. This is like getting 100% on a 10 point test. •Option 2: Construct a 3 dimensional model showing semiconservative DNA replication. Construct a model as in option 1, but also illustrate correctly DNA replication. Add appropriate enzymes to the model, and clearly label the leading and lagging strands and ozaki fragments. 11 points awarded into an optional 10 point test. This is like getting 110% on a 10 point test. Option 3: Construct a 3 dimensional model showing transcription and translation. Construct a model as in option 1, but also illustrate correctly transcription of mRNA, and translation. Clearly label DNA, mRNA, tRNA, ribosome, amino acids in growing polypeptide chain. Follow all rules of base pairing and correctly translate the genetic code of at least four codons 12 points awarded into an optional 10 point test. This is like getting 120% on a 10 point test. Extra Credit Performance Opportunity (two students may collaborate on the performance project): The assignment: Design and perform a protein synthesis musical video and post it on YouTube or another internet video hosting site. For ten out of ten points, the video must correctly: Explain the processes of transcription and translation And must include accurate and complete descriptions of the roles of •DNA •mRNA •tRNA •ribosomes •amino acids •proteins Here are a few examples: This one is cute but not complete for our assignment: http://www.youtube.com/watch?v=gqvYOr78THo&feature=related This one done as a PowerPoint: http://www.google.com/url?sa=t&source=web&ct=res&cd=1&ved=0CAkQFjAA&url=http://www.nclark.ne t/cellwillsurvive.ppt&ei=03dfS6K5DZGssgPcgY21Cw&usg=AFQjCNHhhoX0UPJK688peW0aMsYlFM9h Rg&sig2=mAcAKgNR2TfxrTwqg9dz0w By some students: http://www.youtube.com/user/missbiologybaby - p/a/u/0/ZHiML0AQyIY A wonderful 1970’s (college student) version: http://www.youtube.com/watch?v=u9dhO0iCLww A somewhat updated version of the same (also college students): http://www.youtube.com/watch?v=eOqFlynf8JA I’m not sure about this one: http://www.youtube.com/watch?v=is4MpK44s-o A completed project will earn 10 points as an optional assignment. Two students may work together and submit one performance project.
