Download High Affinity Monoclonal Antibodies

High Affinity
Monoclonal Antibodies
Introduction
Randox Life Sciences was founded in 1982 in the United
Kingdom as a division of our parent company, Randox
Laboratories. We develop and manufacture a wide range
of products including high quality antibodies and conjugates
targeting drugs of abuse, steroids, hormones and biochemical
markers. We also offer customers our extensive list of human
recombinant cytokines, chemokines, adhesion molecules and
tumour markers.
Our product range consists of over 1000 products that are
all manufactured in our state of the art, ISO 13485 accredited
facility. As well as our ever expanding range, we can provide
a number of services such as custom production and
technical support. Our products can be used in a multitude
of applications including ELISA, Lateral flow, Western Blot
analysis and immunofluorescence.
With over 30 years experience in manufacturing and
developing antibodies, we know how important quality is in
creating testing kits as many of our products have been used
in the development of our parent company’s diagnostic kits,
including the patented Biochip Array Technology.
Monoclonal Antibodies
Our monoclonal antibody products are produced in sheep
for use in both research and commercial development.
Sheep monoclonal antibodies have been shown to have
higher affinities than standard mouse monoclonal antibodies
and have also been shown to have a much broader range of
epitope recognition. When looking to develop immunoassays,
this translates into an increase in your assay sensitivity and
precision, ultimately leading to many technical and commercial
advantages;
• Specificity – as the antibody only binds to one specific
region, it is possible to produce a highly specific antibody
for the required target. Alternatively, a generic antibody
can also be produced that binds to a common epitope
on all cross reactants
• Affinity – each antibody molecule binds to the target with
the same affinity – therefore it is possible to produce
monoclonal antibodies with extremely high affinity
• Cross reactivity can be eliminated
General monoclonal specification
Host Animal: Sheep
Format: Purified high affinity monoclonal antibody
pH: 7.2
Buffer: PBS
Preservative: 0.09% Sodium Azide
Method of Production: In vitro cell culture using standard DMEM media supplemented with foetal bovine
serum of a USDA approved origin
Method of Purification: Protein A Affinity Chromatography
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Products
Drug Residues
Drugs of Abuse
17α Hydroxy Progesterone
Cortisol
DHEA-S
Estradiol
Methylprednisolone
Norfloxacin
Progesterone
Salbutamol
SEM
Tetracycline
EDDP
Norketamine
Normeperidine
Secobarbital
TCA
ETG
Biochemical markers
Apolioprotein E4
Creatinine
Glutathione S-Transferase Omega 1 Mutant
Glutathione S-Transferase Omega 1 Wild-Type
Granulocyte Macrophage Colony Stimulating Factor
Intercellular Adhesion Molecule 1
L-Selectin
Thyroid Stimulating Hormone Beta Specific Capture
Thyroid Stimulating Hormone Beta Specific Detector
Vascular Cellular Adhesion Molecule
cTnI Epitopes
Epitope 1-20
Epitope 1-20 Detector 1
Epitope 170-189 Detector 2
Epitope 170-189
Epitope 21-39
Epitope 80-89
Epitope 80-89 Capture
Epitope 190-209
FABP
H-FABP (Heart-Type Fatty Acid Binding Protein) Clone 1
H-FABP (Heart-Type Fatty Acid Binding Protein) Clone 2
H-FABP (Heart-Type Fatty Acid Binding Protein) Capture
Clone 3
H-FABP (Heart-Type Fatty Acid Binding Protein) Detector
Clone 4
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Custom
Manufacturing
Services
With 300 research scientists and over 30 years experience in
commercial assay development Randox Life Sciences can provide a
tailor made assay development service to meet your specifications.
Randox Life Sciences has accumulated considerable experience
and expertise in the custom manufacture of high quality polyclonal
and monoclonal antibodies as well as recombinant proteins and
recombinant antibody fragments (ScFv’s).
Our customisation service has proved incredibly
successful in the research and development
industries, allowing the customer to use our
expertise to obtain the antibody and/or protein
most relevant to their line of work.
Order online:
www.randox-lifesciences.com
Pdf Download:
Randox Life Sciences, 55 Diamond Road, Crumlin, County Antrim, BT29 4QY, United Kingdom
T +44 (0) 28 9442 2413 F +44 (0) 28 9445 2912 E [email protected] I www.randox-lifesciences.com
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Information correct at time of print.
Randox Laboratories Limited is a subsidiary of Randox Holdings Limited a company registered within Northern Ireland with company number N.I. 614690. VAT Registered Number: GB 151 6827 08. Product availability may vary from country to country. Please contact your local
Randox representative for information. Products may be for Research Use Only and not for use in diagnostic procedures in the USA