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Transcript
Carbapenemase-producing Bacteria
MULTIDRUG RESISTANCE AMONG GRAM-NEGATIVE
BACTERIA HAS BEEN INCREASINGLY REPORTED IN THE
LAST TEN YEARS. THE EMERGENCE OF
CARBAPENEMASE-PRODUCING BACTERIA IS OF
PARTICULAR CONCERN AS IT LEAVES VERY FEW
THERAPEUTIC OPTIONS FOR INFECTIONS WITH THESE
TYPES OF BACTERIA.
26
CARBAPENEMASE-PRODUCING GRAM-NEGATIVE ORGANISMS IDENTIFIED IN
SCOTLAND IN 2014, WHICH IS THE AT THE SAME LEVEL AS 2013.
8
1
KLEBSIELLA PNEUMONIAE CARBAPENEMASE-PRODUCING CLONE OF
K. PNEUMONIAE ST258 IDENTIFIED.
NEW-DEHLI METALLO-BETA-LACTAMASES IDENTIFIED. THE OCCURRENCE OF THESE ISOLATES IN THE COMMUNITY IS A CONCERN.
2 INCIDENTS OF LOCAL SPREAD OF CARBAPENEMASE-PRODUCING
BACTERIA MEANS THAT SCOTLAND IS NOW BEING REPORTED AS A COUNTRY
WITH ‘REGIONAL SPREAD’.
CARBAPENEMASE-PRODUCING BACTERIA HAVE BEEN REPORTED WORLDWIDE.
INCREASING INTERCONTINENTAL
TRAVEL HAS CONTRIBUTED TO
THEIR SPREAD.
Is.
2.2%
INCREASE IN THE USE OF CARBAPENEMS BETWEEN 2012 AND 2013.
THIS CONTINUES THE UPWARD TREND OBSERVED IN PREVIOUS
YEARS.
it is CRITICAL TO PRESERVE THE USE OF THESE ANTIBIOTICS
DUE TO LACK OF NEW ANTIBACTERIALS UNDER
DEVELOPMENT.
INTERVENTIONS AND QUALITY IMPROVEMENT to CONTAIN Carbapenemase-producing Bacteria
• REVIEW OF GUIDANCE
• SCOTTISH ANTIMICROBIAL PRESCRIBING GROUP (SAPG) GUIDANCE WITH RECOMMENDATIONS
FOR EMPIRICAL AND TARGETED USE OF CARBAPENEMS • RAPID IDENTIFICATION THROUGH SCREENING
(TWO-STEP CLINICAL RISK ASSESSMENT) • SURVEILLANCE