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should phage therapy be approved in the us?
should phage therapy be approved in the us?

... antimicrobial-resistant microorganisms (between humans, between animals, and between humans and animals and the environment). Genes encoding antibiotic resistance proteins (such as enzymes that degrade antibiotics) often occur on plasmid DNAs that are mobile and easily transmitted between bacteria. ...
Phage Therapy: Eco-Physiological Pharmacology
Phage Therapy: Eco-Physiological Pharmacology

... Bacterial virus use as antibacterial agents, in the guise of what is commonly known as phage therapy, is an inherently physiological, ecological, and also pharmacological process. Physiologically we can consider metabolic properties of phage infections of bacteria and variation in those properties a ...
The Management of Urinary and Male Genital
The Management of Urinary and Male Genital

... Urinary tract infections (UTIs) are among the most prevalent infectious diseases with a substantial financial burden on society. Unfortunately, in Europe, there are no good data concerning the prevalence of various types of UTIs and their impact on the quality of life of the affected population. Nor ...
Diseases and Conditions Table: Recommendations for
Diseases and Conditions Table: Recommendations for

... This manual is intended to support staff in caring for residents living in Alberta Health Services (AHS) owned and contracted Continuing Care settings who have a known or suspected infectious disease or condition. It is organized in alphabetical order based on either the common or scientific spellin ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)

... is so called because there is an abscessus (Latin word means “a going away or departure”) of portions of the tissue from each other to make room for the suppurated matter lodged between them. Empyema is the accumulation of pus in a preexisting rather than a newly formed cavity. The process of absces ...
Burkholderia pseudomallei and Burkholderia mallei
Burkholderia pseudomallei and Burkholderia mallei

... Although some of these reports are from incorrect species diagnosis, others are confirmed, making the endemic limitations of melioidosis very unclear.5 Sporadic cases and occasional case clusters have recently occurred in Brazil and elsewhere in the Americas.23 Despite recent cases from Madagascar,2 ...
Triclosan - Tufts University
Triclosan - Tufts University

... mammals. However, there have been reports (17) of contact dermatitis, or skin irritation, from exposure to triclosan. There is also evidence (18) that triclosan may cause photoallergic contact dermatitis (PACD), which occurs when the part of the skin exposed to triclosan is also exposed to sunlight. ...
Triclosan White Paper prepared by The Alliance for the Prudent Use... January 2011
Triclosan White Paper prepared by The Alliance for the Prudent Use... January 2011

... has been extensively studied in laboratory animals. When evaluated in chronic oncogenicity studies in mice, rats, and hamsters, treatment-related tumors were found only in the liver of male and female mice (24). Application of the Human Relevance Framework suggested that these tumors arose by way of ...
Appendix D: Nursing and Provider Antibiotic Use Attitudes and Beliefs Surveys (PDF: 417KB/29 pages)
Appendix D: Nursing and Provider Antibiotic Use Attitudes and Beliefs Surveys (PDF: 417KB/29 pages)

... difficile, or C. diff, to overgrow. Every exposure to antibiotics puts residents at risk for developing what the Centers for Disease Control and Prevention (CDC) have called ‘deadly diarrhea.’ ...
PDF
PDF

... When food (e.g., bacteria) is plentiful, amoebae survive and proliferate as single-celled amoebae. However, once the food source has been depleted from an area, some species of amoebae cooperate to spread to new, more fertile hunting grounds. In the case of D. discoideum, this cooperation involves a ...
Serratia Infections: from Military Experiments to Current Practice
Serratia Infections: from Military Experiments to Current Practice

... In the late part of the 19th century, William Coley, an oncologist, developed a formula consisting of Streptococcus pyogenes and S. marcescens that he used to treat sarcoma (219). This treatment, called by names such as Coley’s fluid, Coley’s vaccine, Coley’s toxins, and mixed bacterial vaccine, was ...
OIE International Standards on Antimicrobial Resistance, 2003
OIE International Standards on Antimicrobial Resistance, 2003

... The increasing antimicrobial resistance of important human pathogenic bacteria, and the spread of such bacteria from the closed environment of hospitals into surrounding communities, are increasingly perceived as threats to public health. Any use of antimicrobials, whether in humans, animals, plants ...
ABSTRACT Title of Document:
ABSTRACT Title of Document:

... diseases in humans, as well as myriad animal species. However, the excess or overuse of antibiotics can generate genomic selective pressures to enable microbes to adapt and acquire resistance (Witte, 2000). Antibiotic resistance is an evolutionary artifact of microbes adapting to environmental chang ...
hepatitis c - Journal of the International AIDS Society
hepatitis c - Journal of the International AIDS Society

... migrants and persons who use drugs. Epidemic concentration in urban areas, especially among: population sub-groups with high prevalence of risk behaviours; the socio-economically marginalized; or those with poor access to services, has been well documented. Recent increases in HIV incidence in the r ...
Clostridium difficile - Utrecht University Repository
Clostridium difficile - Utrecht University Repository

... Clostridium difficile is a known cause of diarrhea in neonatal piglets. The objective of this study was twofold. The first objective was to determine the sensitivity of the diagnostic procedures used. At three sow herds fecal samples of neonatal piglets suspected from Clostridium difficile- associat ...
Community-acquired pneumonia in children: Clinical features and
Community-acquired pneumonia in children: Clinical features and

... from Streptococcus pneumoniaeand less commonly from Staphylococcus aureus and group A Streptococcus, which may follow days of upper respiratory tract infection symptoms, is considered abrupt in onset, with the febrile patient appearing ill and sometimes toxic. Respiratory distress is moderate to sev ...
Helicobacter pylori
Helicobacter pylori

... H. pylori is composed of a single circular chromosome with ...
Cysteamine (Lynovex®), a novel mucoactive antimicrobial
Cysteamine (Lynovex®), a novel mucoactive antimicrobial

... an effective mucolytic and biofilm disrupter/preventer, outperforming currently licensed mucolytic/osmotic agents in these functions. Surprisingly, cysteamine was also directly antimicrobial against P. aeruginosa; including mucoid and non-mucoid strains and clinical isolates. Cysteamine was also act ...
MOLECULAR CHARACTERISATION OF METHICILLIN-RESISTANT PHUTI EDWARD MAKGOTLHO  Staphylococcus aureus
MOLECULAR CHARACTERISATION OF METHICILLIN-RESISTANT PHUTI EDWARD MAKGOTLHO Staphylococcus aureus

... for most of health-care associated infections throughout the world. However, in recent years, a more virulent strain of MRSA has emerged in the community defined as community-associated MRSA (CA-MRSA). These emerging strains of CA-MRSA are described to have different antibiotic susceptibility profil ...
Chlorhexidine compounds in cosmetic products Risk assessment of
Chlorhexidine compounds in cosmetic products Risk assessment of

... Enterobacteriaceae. This resistance may result from increased expression of chromosomally located efflux pumps, acquisition of plasmid-encoded efflux pumps, or changes in susceptibility by other presently unknown mechanisms. Literature on the development of resistance due to chlorhexidine in cosmeti ...
CURRICULUM VITAE MIGUEL A. VALVANO, MD. Centre for
CURRICULUM VITAE MIGUEL A. VALVANO, MD. Centre for

... are of fundamental biological importance not only for bacteria but also for all cells. This research also led to proof of principle evidence that novel compounds can be identified (called antibiotic adjuvants), which can increase the permeability of the bacterial outer membrane to common antibiotics ...
- Journal of the International AIDS Society
- Journal of the International AIDS Society

... It remains controversial whether and, if so, the extent to which antiretroviral therapy (ART) results in net benefit if used by HIVpositive persons with a high CD4 count, particularly those with early HIV infection. This controversy is primarily reflecting lack of solid evidence from randomized cont ...
Linköping University Post Print Vaginal cleansing and postoperative infectious
Linköping University Post Print Vaginal cleansing and postoperative infectious

... infectious morbidity are shown in Table 4. Young age (< 40 years of age), obesity, operation time exceeding 90 minutes, peroperative injury of the urinary bladder, and duration of hospital stay exceeding 2 days, were statistically significant risk factors. Contrarily, prophylactic antibiotics and co ...
Virulence factors of enteropathogenic Escherichia co/i
Virulence factors of enteropathogenic Escherichia co/i

... have a role in the pathogenesis of EPEC diarrhoea, other factors were likely to be involved because some VT-negative strains were known to be pathogenic in human volunteers. Wade et al. (1979) also presented evidence of the possible significance of VT when they showed that all three VT-positive stra ...
in vitro Mycoplasma origin
in vitro Mycoplasma origin

... synoviae in poultry and bacterin vaccines against M. hyopneumoniae in pigs. With the difficulties associated with the use of these vaccines as well as the lack of vaccines for other mycoplasmal diseases, antimicrobials are increasingly being used to treat and prevent them (Gautier-Bouchardon et al., ...
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Carbapenem-resistant enterobacteriaceae

Carbapenem-resistant enterobacteriaceae (CRE) or Carbapenemase-producing Enterobacteriaceae (CPE), are gram-negative bacteria that are nearly resistant to the carbapenem class of antibiotics, considered the ""drug of last resort"" for such infections. Enterobacteriaceae are common commensals and infectious agents. Experts fear CRE as the new ""superbug"". The bacteria can kill up to half of patients who get bloodstream infections. Tom Frieden, head of the Centers for Disease Control has referred to CRE as ""nightmare bacteria"".
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