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Download Print - Circulation: Cardiovascular Imaging
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Transcript
collaterals. Oxygen saturation at rest ranged between 91 and 97% and did not decrease significantly during dobutamine. There were no statistically significant differences between parameters as measured for the left versus right type single ventricle. This comprises also the function parameters as given below. Blood flow and pulmonary vascular resistance The Nakata index of the pulmonary arteries was 150±45 mm2/m2 and thus substantially below published reference values of healthy controls.1, 18 Quantitative flow volumes measured in the Downloaded from http://circimaging.ahajournals.org/ by guest on May 3, 2017 inferior and superior vena cava were similar to those measured in the left and right pulmonary blle) e).. In all all ppatients, atie at ien ie n there was artery and they all increased during dobutamine (p<0.05) (Table). elll as dduring urin ur ing in g stress (Figure only trivial retrograde flow in the pulmonary arteries, at rest ass wel well tman analysis showed good ood agreement reement between flow measurem 2). The Bland-Altman measurements obtained ure 3).. During augmented pul ppulmonary flow, in the vena cava and the pulmonary arteries (Figure y artery arter pressure essure and trans transpulmonary lmonar pressure essure gradient radient did only change mean pulmonary slightly and, consequently, vascular resistance was decreased (Table). Blood flow volumes were significantly larger when measured in the aorta compared to the pulmonary arteries and, compared to rest, this difference increased during stress (Table). Thus, the calculated collateral blood flow increased significantly during dobutamine (p<0.01). There was no significant correlation between collateral blood flow and ventricular enddiastolic volumes (r=0.072 at rest and r=-0.062 during dobutamine) or between collateral blood flow and cardiac index (r=-0.072 at rest and r=-0.062 during dobutamine). However, there were statistically significant inverse correlations between collateral blood flow (APC) and both PVR and ergometry derived peak oxygen uptake (r=-0.6, p=0.03 and r=-0.7, p=0.01). Blood flow patterns in the pulmonary arteries were similar at rest and during dobutamine (Figure 2). The profiles showed, in concordance to other reports, some degree of inter-individual variability.28, 29
