Download Nuclear Medicine: Ejection Fraction

Ejection fraction
Definition
Ejection fraction is an evaluation of the function of the left ventricle, also called left ventricular ejection fraction (LVEF). It calculates the
proportion of blood ejected from the left ventricle with each heartbeat. If the percentage is lower than 50 percent, then cardiomyopathy
may be present (Richard N. Fogoros, 2003).
Role of molecular imaging
The multiple gated acquisition (MUGA) scan is a non-invasive tool for assessing the function of the heart. The MUGA scan generates a
non-static or moving image of the beating heart, which gives an accurate and reproducible means of measuring and monitoring the
ejection fraction of the cardiac ventricles. In heart attack cases, a MUGA scan localizes the damaged portion of the heart muscle to
evaluate extent of damage.
Radiopharmaceutical
Manufacturer
Trade names
Approved indications in adults
Technetium-99m red blood
cells
Covidien
UltraTag™
Tc99m-labeled red blood cells are used for:
blood pool imaging including cardiac first pass
and gated equilibrium imaging
Technetium-99m sestamibi
Cardinal Health
Covidien
DRAXIMAGE
Lantheus Medical
Imaging
Pharmalucence
Technetium-99m tetrofosmin
GE Healthcare
®
Myocardial perfusion agent that is indicated for:
 Detecting coronary artery disease by
localizing myocardial ischemia
(reversible defects) and infarction (nonreversible defects)
 Evaluating myocardial function
 Developing information for use in
patient management decisions
Myoview™
Myocardial perfusion agent that is indicated for:
 Detecting coronary artery disease by
localizing myocardial ischemia
(reversible defects) and infarction (nonreversible defects)
 The assessment of left ventricular
function (left ventricular ejection
fraction and wall motion)
Cardiolite
MSDS and package insert information
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