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Biochemistry and Much, Much More An Introduction to the Chemistry of Life Five Common Acids 1. 2. 3. 4. 5. Acetic Acid: CH3COOH Hydrochloric Acid: HCl Nitric Acid: HNO3 Sulfuric Acid: H2SO4 Phosphoric: H3PO4 The Magnificent Seven 1. 2. 3. 4. 5. 6. 7. N2 H2 O2 F2 Cl2 Br2 I2 What is Life Made of? § Physical and Chemical sciences alone may not completely explain the nature of life, but they at least provide the essential framework for such an explanation. § All students of life must have a fundamental understanding of organic chemistry and biochemistry. Organic Chemistry § Organic chemistry is the study of Carbon compounds. § Organic compounds are compounds composed primarily of a Carbon skeleton. § All living things are composed of organic compounds. Organic Chemistry § What makes Carbon Special? Why is Carbon so different from all the other elements on the periodic table? § The answer comes from the ability of Carbon atoms to bond together to form long chains and rings. Organic Chemistry Organic Chemistry Carbon can covalently bond with up to four other atoms. Carbon can form immensely diverse compounds, from simple to complex. Methane with 1 Carbon atom DNA with tens of Billions of Carbon atoms Polymers and Monomers § Each of these types of molecules are polymers that are assembled from single units called monomers § Carbohydrate § Protein § Nucleic Acid Monomers Polymer Carbohydrates Monomer Monosaccharide Proteins Amino acids Nucleic acids Nucleotides Carbohydrates § Carbohydrates are made of carbon, hydrogen, and oxygen atoms, always in a ratio of 1:2:1. § Carbohydrates are the key source of energy used by living things. § The building blocks of carbohydrates are sugars, such as glucose and fructose. Carbohydrates § What do the roots § mono-, di-, oligo-, and poly mean? § Each of these roots can be added to the word saccharide to describe the type of carbohydrate you have. Polysaccharides § Most common type of carbohydrate Proteins § Proteins are building blocks of structures called amino acids § Proteins have four levels of structure § A peptide bond forms between amino acids (monomers in a protein) § There are 20 kinds of amino acids Nucleic Acids § Basic unit (monomer) is nucleotide § Nucleotides made up of nitrogen base, phosphate and sugar