Download CE Exam - Laboratory Medicine

CE Exam
Specimen Age Stability for Human Papilloma
Virus DNA Testing Using BD SurePath
Melanie J. Kubik, MD
University of Florida College of Medicine – Jacksonville, Department of Pathology & Laboratory Medicine
Lab Med Winter 2015;46:e13
DOI: 10.1309/LMX0ZO0AKOG8HCSZ
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issue). Continuing Educations Exams are approved to meet licensure
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Course ID: CEUDCY31501
1. Which statement is true about Human Papilloma
Virus (HPV) testing?
a. Cytology (i.e. Pap test) can reliably be used as alonestanding screening tool for HPV infection
b. There is only one method for HPV DNA detection
c. SurePath is FDA approved for Pap test only
d. For HPV DNA testing, there are strict guidelines for
specimen age of SurePath specimens
4. How do the gene products of viral DNA change the
host cell cycle?
a. By causing a mutation in KRAS and EGFR genes
b. By binding to tumor suppressors p53 and
retinoblastoma gene product RB
c. By suppressing P16 gene
d. By overexpression of Her-2neu protein
2. How many new cases of cervical SCC are
diagnosed annually?
a. 20,000
b.12,000
c.50,000
d.4,000
3.
a.
b.
c.
d.
5. All of the following are examples of HR-HPV
except:
a. 16 & 18
b. 6 & 11
c. 31 & 35
d. 39 & 45
All of the following are true about HPV except:
HPV is a double-stranded DNA virus
HPV enters the basal cell layer of the epithelium
HPV becomes integrated into the host DNA
The E6 and E7 gene products of viral DNA deregulate
the host cell cycle in favor of apoptosis
www.labmedicine.com
Winter 2015 | Volume 46, Number 1 Lab Medicine e13