Download homeostasis in cortical neurons nicotinamide adenine dinucleotide

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of June 18, 2017.
HIV-1 Trans activator of transcription
protein elicits mitochondrial
hyperpolarization and respiratory deficit,
with dysregulation of complex IV and
nicotinamide adenine dinucleotide
homeostasis in cortical neurons
J. P. Norman, S. W. Perry, K. A. Kasischke, D. J. Volsky
and H. A. Gelbard
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Copyright © 2007 by The American Association of
Immunologists All rights reserved.
Print ISSN: 0022-1767 Online ISSN: 1550-6606.
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J Immunol 2007; 178:3334; ;
doi: 10.4049/jimmunol.178.5.3334
http://www.jimmunol.org/content/178/5/3334
3334
CORRECTIONS
Norman, J. P., S. W. Perry, K. A. Kasischke, D. J. Volsky, and H. A. Gelbard. 2007. HIV-1 Trans activator of
transcription protein elicits mitochondrial hyperpolarization and respiratory deficit, with dysregulation of complex IV and
nicotinamide adenine dinucleotide homeostasis in cortical neurons. J. Immunol. 178: 869 – 876.
Throughout the article, NAD(P)H should have been used in place of NADPH to signify both NADH and NADPH, and
NAD(P)H should have been included with the standard abbreviations given in Footnote 3. The corrected footnote is
shown below.
3
Abbreviations used in this paper: HAD, HIV-1-associated dementia; ⌬␺m, mitochondrial membrane potential; ⌬p, proton motive force; ETC, electron
transport chain; FCCP, carbonyl cyanide-4(trifluoromethoxy)phenylhydrazone; NMDA, N-methyl-D-asparate; pHm, mitochondrial pH; PTD, protein transduction domain; rhod123, rhodamine 123; Tat, trans activator of transcription protein; EYFP, enhanced yellow fluorescent protein; CFP, cyan fluorescent
protein; NAD(P)H, signifies both NADH and NADPH.
In Results, in the fifth heading, the words “NAD⫹/NADH ratio and NADPH” are incorrect. Under that heading, in the
fourth sentence of the second paragraph, the ␦ symbol should have been uppercase. The corrected heading and sentence
are shown below.
The effect was specific for Tat, because the application of ⌬31– 61 Tat did not result in an observable fluorescence change.
The errors have been corrected in the online version, which now differs from the print version as originally published.
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Effects of HIV Tat on NAD(P)H fluorescence