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Chapter 12 Digestion The Start of Digestion • The Mouth Food enters here • The Teeth mechanically breaks down food • The Tongue Chemically recognizes food. Moves food around the mouth. Assists in swallowing • Salivary Glands Releases Saliva into the mouth. Saliva starts chemical breakdown and moistens food for swallowing. • The Pharynx The area in the very back of the mouth that receives air from the nasal cavities (air from the nose) and food from the mouth. • Esophagus The food tube. The tube that goes from the mouth to the stomach. Many muscles surround this tube to help swallow. When muscles work to swallow its called Peristalsis • Trachea Tube that goes down to the lungs to breath. This has cartridge rings so it is always open. • Epiglottis covers the Trachea when swallowing so food does not go down into the lungs. Teeth Nasal Cavity Pharynx Mouth Cavity During swallowing the Trachea moves up and forces the Epiglottis to close over the trachea’s opening Swallowing • Step 1: food is chewed in the mouth. Saliva is added for lubrication. Saliva also contains the digestive enzyme Salivary amylase. This enzyme breaks down starches into disaccharides like maltose • Step 2: Food is turned into a Bolus ( a ball of food) and pushed back of mouth by tongue. • Step 3: Muscles move the bolus down the esophagus. This is called peristalsis. The trachea moves up and the epiglottis closes access to the trachea. A muscle in the pharynx closes access to the nasal cavity Nasal Cavity Pharynx Epiglottis Trachea Esophagus Bolus Trachea Into the Stomach • The bolus moves down the esophagus and into the stomach. • The cardiac sphincter prevents the food from going from the stomach back up the esophagus. • A sphincter is a muscle that goes around a tube to act as a valve. • The cardiac sphincter is located at the joining of the stomach and the esophagus • The stomach has many gastric glands the release gastric juices into the stomach • Gastric Juice Contains: – Pepsin enzyme breaks proteins to peptides – HCl acid the acid kills some bacteria, activates pepsin, and breaks up food (but does not digest) – Mucus slime that covers your stomach wall to protect it against the acid • Muscles around the stomach help mix the food with the gastric juices Cardiac Sphincter a Into the Small Intestine • After the stomach the pyloric sphincter opens and lets Chyme pass on into the small intestine • The first part of the small intestine is called the duodenum • The duodenum has ducts that enter the duodenum that release many different chemicals • Duodenum releases – Bile comes from liver. Bile is often stored in the Gall Bladder Emulsifies fat. – Pancreatic Juices • Juices from the organ called the pancreas • Sodium bicarbonate NaHCO3 turns the acidic chyme basic • Pancreatic amylase breaks down starch into disaccharides. Enzyme. • Trypsin breaks down protein into peptides. Enzyme • Lipase breaks down fat. Enzyme • Nuclease breaks down nucleic acid into nucleotides • The small intestine is designed to absorb nutrients. – It has a huge surface area. This is because the inside of the small intestine has finger-like projections called villi. Each villi has finger-like projections called microvilli • The small intestine has a thin layer of mucus over it. Under the mucus are the villi and microvilli. Sugars and amino acids pass through the mucus and get moved into the blood vessels. Enzymes of the Small Intestine • The small intestine has many enzymes that work there to help let materials pass through the wall of the small intestine – Maltase digests maltose into glucose – Peptidase digests peptides into amino acids – Nucleosidases digests nucleotides into bases, sugar, and phosphate • Amino acids, sugars, and components of nucleotides, move into the blood by going through the microvilli • The parts of Fat (glycerol and fatty acids ) get moved into the Lacteal. • The lacteal is part of the lymphatic system. Moving into the Large Intestine • The Large Intestine is shorter in length but wider in diameter • Made up of several parts – Ascending colon – part of colon that goes up – Transverse colon – part of colon that goes along side – Descending colon – part of colon that goes down – Cecum – attached to ascending colon. Goes nowhere – Appendix – attached to cecum. Can get infected. – Rectum – where all the feces is stored. End of colon. – Anus – the muscular opening to expel feces. Transverse Colon Ascending Colon Descending Colon Cecum Rectum Appendix Anus What happens in the Large Intestine • The large intestine is full of bacteria. A lot the bacteria are anaerobic bacteria. – Anaerobic bacteria bacteria that do not use oxygen. Bacteria that will die in the presence of oxygen. • These bacteria break down indigestible materials. They also produce some vitamins that are then absorbed by the large intestine wall. • The large intestine absorbs water out of the waste Identify all the parts • Salivary Glands Review – Salivary amylase, moistens food • Stomach – Gastric Juices: Pepsin, HCl, Mucus • Pancreas – Pancreatic Juices: NaHCO3, Trypsin, Lipase – Insulin hormone is secreted into the blood • This hormone tells cells in the body to take up glucose • This hormone is released after eating when there is high glucose levels in the blood • Pancreas – Blood glucose levels are high releases Insulin • Insulin causes cells to take up glucose – Blood glucose levels are low releases Glucagon • Tells body to break down glycogen into glucose. Glycogen is found in the liver • Tells body to break down fat into glycerol and fatty acids. • Liver =O – Makes Bile – Removes any poisons from the blood – Stores Iron and many vitamins – Stores glycogen. This can be made into glucose – Regulates blood cholesterol levels – Produces Urea: • 2NH3 + CO2 H2N-C-NH2 + H2O Optimal pH for the Enzyme Enzyme Location pH Salivary Amylase Pancreatic Amylase Pepsin Trypsin Mouth. Salivary Gland Duodenum. Pancreas Stomach Pancreas. Duodenum Neutral Basic Acidic Basic Peptidase Nuclease Nucleosidase Small Intestine Pancreas. Duodenum Small Intestine Basic Basic Basic Lipase Pancreas, Duodenum Basic SOURCE ENZYME FOOD PRODUCT MOUTH (salivary glands) Salivary amylase Polysaccharides Maltose STOMACH Pepsin Proteins Peptides PANCREAS Pancreatic amylase Polysaccharides Trypsin Proteins Lipase Fats SMALL INTESTINE Maltase Peptidases Maltose Peptides Maltose Peptides Fatty acids and glycerol Glucose Amino acids FOOD TYPE ENZYME SOURCE PRODUCTS CARBOHYDRATES Salivary amylase Pancreatic amylase Maltase Salivary glands Pancreas Small intestine Maltose Maltose Glucose PROTEINS Pepsin Trypsin Peptidases Stomach mucosa Pancreas Intestinal mucosa Peptides Peptides Amino acids FATS Lipase Pancreas Fatty acids and glycerol Polysaccharides Maltose Salivary amylase Pancreatic Amylase Glucose Maltase Name the Enzyme Involved Proteins Peptides Pepsin Trypsin Fats Amino Acids Peptidase Lipase Glycerol + Fatty Acids Remember to Drink lots of water