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Characteristics of Viruses – Part 1 Similarities and Differences between Viruses and Cells If you ever had a cold or the flu, you probably hosted viruses. A virus is an infectious agent made up of a core of nucleic acid and a protein coat. Viruses are not cells. Unlike plant and animal cells, a virus package does not include many parts , such as a nucleus, a membrane or organelles that a cell has. Examples of the cellular organelles that are absent in viruses include: ribosomes, mitochondria and chloroplasts. Although viruses are not cells, they do have organized structural parts. Compared to even the smallest cell, a virus is tiny. The virus that causes polio, for example, measures only 20 nanometers in diameter. One nanometer is one billionth of a meter. At that size, 3000 polioviruses could line up across the period at the end of this sentence. All viruses have at least two parts: a protective protein coat and a core of nucleic acid. The protein coat around the core of the nucleic acid is called a capsid. Depending on the virus, the capsid may consist of one or several kinds of protein. The capsid protects the viral nucleic acid core from its environment. In cells, DNA is the hereditary material. Some viruses also contain DNA, while other viruses contain only RNA. In viruses containing RNA, the RNA functions as the hereditary material. Compared to a cell, a virus has a relatively simple existence. Viruses do not eat, respire, or respond to environmental changes as cells do. It should not surprise you, therefore, to learn that viruses have fewer genes than cells have. While a human cell may contain about 100,000 genes and the bacterial cell about 1000, a virus may contain only 5 genes. An Influenza Virus Envelope An envelope is made of an outer lipid layer and an inner protein layer surrounding the capsid. RNA The influenza virus has a total of eight strands of RNA. Many viruses contain DNA rather than RNA. Projections Capsid The proteins in a capsid are determined by the genes in the virus. The spike-like projections on the viral envelope help the virus recognize and attach to a host cell. Next Page