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Introduction to Genetics Chapter 11-1 Notes The varied patterns of stripes on zebras are due to differences in genetic makeup. No two zebras have identical stripe patterns. Every living thing – plants, animals, microbes & humans have a set of characteristics inherited from its parents. 1. 2. 3. 4. Genetics: Branch of biology that focuses on heredity. Heredity: The transmission of genetic traits from parent to offspring. Gene: Small sections of DNA that code for specific traits. Trait: Specific characteristic that varies from one individual to another. Before scientists knew about DNA & chromosomes heredity was a great mystery! Gregor Mendel Austrian monk, the “Father of Genetics” Studied heredity in garden peas (Pisum sativum) First to develop rules that predict patterns of heredity Interested in genetics when he crossed two pea plans with purple flowers and noticed the offspring had white flowers. Used “quantitative” methods to analyze results! He actually counted the offspring and studied the numbers. Gregor Mendel 1822 - 1884 Why Peas??? 1. Traits are easy to distinguish (tell apart) * Flower color * Seed color * Seed shape * Flower position 2. 3. * Pod color * Pod shape * Plant height Mating of pea flowers is easy to control Pea plants are small, grow easily, mature quickly and produce many offspring. * You get a lot of results, quickly!! Pea Plant Traits What did Mendel do??? Step 1: Used true-breeding plants Produce offspring identical to themselves Similar to a “pure breed” dog Called these the P (parental) generation Step 2: Crossed two P generation plants, each with a different trait. Offspring called the F1 generation Step 3: Allowed F1 generation to self-pollinate. Offspring called the F2 generation Pea Plant Pollination Mendel’s Experiments Mendel’s Results Monohybrid cross: Involves one pair of contrasting traits. The offspring of crosses between parents with different traits are hybrids Example: Cross a plant with purple flowers and a plant with white flowers. Carry the traits of both parents, but only show the traits of one parent Alleles: Different forms of the same gene 1 gene for plant height 2 alleles: tall and short Mendel’s Conclusions Biological inheritance is determined by genes that are passed from one generation to the next. Each of the traits Mendel studied was controlled by one gene that occurred in two contrasting forms. These different forms produced each of the different traits. For example, the gene for plant height occurs in one form that produces tall plants and in another form that produces short plants. Mendel’s Conclusions Principle of Dominance. The Principle of Dominance states that some alleles are dominant and others are recessive. An organism with a dominant allele for a trait will always exhibit that form of the trait. An organism with a recessive allele for a will exhibit that form only when the dominant allele for the trait is not present. Law of Segregation Mendel wondered...were the recessive alleles disappeared, or were they still present in the plants? He determined that the separation, or segregation, of alleles occurred. Two alleles for a trait segregate from each other so that each sex cell (gamete) carries only a single copy of each gene. Law of Independent Assortment After determining that the alleles segregate during the formation of gametes, Mendel wondered if the segregation of one pair of alleles affect the segregation of another pair of alleles? Mendel found that the inheritance of one trait had no effect of the inheritance of another trait. Example: The gene that determines flower color has nothing to do with the gene that determines plant height. concluded that experimented with which is called the which is called the which is called the Gregor Mendel concluded that experimented with Pea plants “Genes” determine traits Some alleles are dominant, and some alleles are recessive Alleles are separated during gamete formation which is called the which is called the Law of Dominance Law of Segregation Inheritance of one trait has no effect on the inheritance of another trait which is called the Law of Independent Assortment