Download GO ON TO THE NEXT PAGE. -28- 8. In 1952 Alfred Hershey and

8. In 1952 Alfred Hershey and Martha Chase used radioactive phosphorus and radioactive sulfur to selectively
label the DNA and proteins of bacteriophage T2, a virus that infects bacteria. After incubating the labeled
bacteriophage particles with Escherichia coli and separating extracellular phage particles from the bacteria,
Hershey and Chase measured the amounts of radioactive phosphorus and sulfur inside infected E. coli cells and
in the liquid growth medium outside the E. coli cells.
(a) Predict the experimental result that would best support the claim that DNA is the source of heritable
information, and provide reasoning to explain how the result supports the claim.
(b) Bacteriophages, like other viruses, consist primarily of a protein coat and packaged DNA. Describe
the function of ONE critical enzyme in bacterial cells that is necessary for replicating bacteriophage
DNA.
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