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No. 1 2 3 4 Topic 1 – Building Blocks of Cells What is the function of the flagella of a bacteria cell? What is the function of the cell wall of a bacteria cell? What is the function of the chromosomal DNA in a bacteria cell? What is the function of the plasmid DNA in a bacteria cell? What is the function of a plant cell wall? Answers For movement For support and to keep the cell’s shape Carry most of the genetic material for the bacteria To carry small amounts of extra genetic material For support and to keep the shape of the cell 5 What is the function of chloroplasts? 6 What is the function of the vacuole? Contain chlorophyll which absorb light for photosynthesis Contains sap and helps keep the cell rigid 7 What is the function of the cell membrane? 8 What is the function of the cytoplasm? 9 What is the function of the nucleus? 10 What is the function of mitochondria? 11 12 13 14 What piece of equipment lets us see cells in more detail? How can you calculate the magnification of a microscope? How can you calculate the actual length of a specimen under a microscope? What is a gene? 15 Describe a DNA molecule 16 How do the base pairs in DNA pair up? 17 18 19 Who were the scientists involved in the discovery of DNA? What is the significance of the human genome project? How does genetic engineering work? 20 What are some uses of genetic engineering? 21 Controls the movement of substances in and out of the cell Where chemical reactions take place and contains organelles Contains the DNA and controls the cell’s activity They are where respiration takes place for energy A microscope Objective lens magnification X eyepiece lens magnification Length of the magnified object/magnification A section of DNA that codes for a specific protein Two stands in a double helix linked by base pairs in hydrogen bonds Adenine (A) with Thymine (T) Cytosine (C) with Guanine (G) Franklin, Wilkins, Watson and Crick It was a collaboration between many scientists around the world which lead to a better understanding of human biology and many possible medical advances A gene from one organism is extracted and placed into the DNA of another organism Beta carotene in rice used to treat vitamin A deficiency Production of human insulin by GM bacteria Herbicide resistant crops 22 What are some disadvantages of genetic engineering What is a diploid cell? Seen as dangerous by some Unknown consequences in GM organisms get into the wild A cell dividing to produce two genetically identical, diploid, daughter cells A cell dividing to produce four, genetically unique, haploid, daughter cells A cell with two copies of each chromosome What is a haploid cell? A cell with only one copy of each chromosome When does mitosis happen? During growth, repair or asexual reproduction What happens during fertilization in sexual reproduction? What is cloning Two haploid cells combine to make one diploid cell A type of asexual reproduction that produces genetically identical copies 1. Removal of a diploid nucleus from a body cell 2. Enucleating (removing the nucleus) an egg 3. Insertion of diploid nucleus into enucleated egg 4. Stimulation of diploid nucleus to divide by mitosis 5. Implantation into surrogate mammal Replicating individuals with desirable characteristics It is very difficult to do, so uses many egg cells What is mitosis? 23 What is meiosis? 24 25 26 27 28 29 What are the stages in cloning a mammal 30 What are some advantages of cloning? 31 What are some drawbacks of cloning? 32 What are some risks of cloning? 33 What is a stem cell? Possible medical problems with cloned animals, such as premature aging. A cell that can differentiate into any type of cell 34 What are the advantages of stem cell research? 35 What are disadvantages of stem cell research? 36 What are the risks of stem cell research? 37 38 What decides the type and order of amino acids in a protein made in a cell? More reliable treatments for diseases such as leukaemia The ability to produce matching organs for people in need of donor organs It could be used to clone humans illegally Involves destroying human embryos, which some people see as murder. Stem cells could develop into the wrong type of cell or even cancer. The order of the bases in DNA 39 Describe how protein synthesis works? Transcription: Production of a complimentary strand of mRNA in the nucleus Translation: • Attachment of mRNA to a ribosome • Coding by triplets of bases (codons) in the mRNA for specific amino acids • Amino acids transported to the ribosome by tRNA amino acids linked to form a polypeptide chain A polypeptide chain with a specific number and order of amino acids and a specific shape which have different functions such as enzymes A change in the order of DNA bases which causes a change in the amino acid order in a polypeptide and therefore a change in the structure of the final protein produced. They can be harmful, beneficial or neither. Biological catalysts DNA replication Protein synthesis Digestion Temperature pH Concentration Enzymes are a specific shape to fit their substrate An enzyme that doesn’t work because the shape of the active site has changed its shape • Describe a protein 40 41 What is a gene mutation? 42 43 What is an enzyme? Give some examples of reactions that enzymes catalyse 44 What factors affect enzyme action? 45 What is the ‘lock and key’ hypothesis of how enzymes work Define a denatured enzyme 46 Topic 2 – Organisms and Energy What is respiration? 47 48 In what two ways does the human circulatory system facilitate respiration? Define diffusion 49 Describe aerobic respiration 50 Give a word equation for aerobic respiration The process by which all living organisms release energy from organic molecules 1. Glucose and oxygen diffuse from capillaries into respiring cells 2. Carbon dioxide diffuses from respiring cells into capillaries The movement of particles from an area of high concentration to an area of low concentration The use of oxygen to release energy from glucose, producing water and carbon dioxide as by-products Oxygen+glucoseàcarbon dioxide+water 51 52 Why do heart rate and breathing rate increase during exercise? Exercising muscles are doing more aerobic respiration to produce energy, so need more oxygen and glucose. Waste carbon dioxide can also be removed quicker. 53 How can you calculate cardiac output? What is cardiac output? 54 What is stroke volume? 55 56 57 58 64 What is heart rate? What is anaerobic respiration? Why do cells have to respire anaerobically sometimes during vigorous exercise What is the word equation for anaerobic respiration? What produces more energy, aerobic or anaerobic respiration? How is lactic acid broken down and removed from the body? What is EPOC What do heart rate and breathing rate remain high after exercise has finished? How is a leaf adapted for photosynthesis? 65 66 67 What is the word equation for photosynthesis? What provides the energy for photosynthesis? What is a limiting factor? 68 Give three examples of limiting factors 69 What is transpiration and what drives it 70 71 How is water taken into the roots of a plant? How are minerals taken into the roots of a plant? What do xylem vessels transport? What do phloem vessels transport Define osmosis 59 60 61 62 63 72 73 74 75 76 77 How is a root hair cell adapted for absorbing water What equipment can be used to sample the distribution of organisms in an ecosystem? What factors can affect the distribution of organisms in an ecosystem? Stroke volume X heart rate The volume of blood leaving the heart every minute The volume of blood leaving the heart every beat The number of times the heart beats per minute Respiration without oxygen The cells cannot get enough oxygen to meet the energy demand through aerobic respiration Glucose à Lactic acid Aerobic respiration It reacts with oxygen to form carbon dioxide and water, which are removed in the blood Excessive post exercise oxygen consumption Your cells still need oxygen to break down the lactic acid built up during exercise Large surface area Lots of chlorophyll Stomata for gas exchange Carbon dioxide+wateràoxygen+glucose Light Something that can limit the maximum rate of photosynthesis due to its lack of availability Light intensity Carbon dioxide concentration Temperature The movement of water through a plant, driven by the evaporation of water from the leaves Osmosis Active transport (requiring energy) Water and minerals Glucose The movement of water from an area of high concentration to an area of low concentration through a semi-permeable membrane Large surface area No Chloroplasts • Pooters • Sweep nets/pond nets • Pitfall traps • Quadrats • Light intensity • Temperature • pH 78 Topic 3 – Common Systems How do fossils give evidence for evolution? 79 Why are there some gaps in the fossil record? 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 How do pentadactyl limbs provide evidence for evolution? What is ‘growth’ What causes plants to grow? What causes growth in animals? What is the structure and function of a red blood cell? What is the structure and function of white blood cells? What is the structure and function of platelets? What is the structure and function of blood plasma What is a tissue? What is an organ? What is an organ system? What are the four major blood vessels of the heart? Where does the aorta go from and to? Where does the vena cava go from and to? Where does the pulmonary artery go from and to? Where does the pulmonary vein go from and to? Which side of the heart pumps oxygenated blood? Which side of the heart pumps deoxygenated blood What is the job of the heart valves Which ventricle has a thicker wall and why? What direction to arteries carry blood What direction do veins carry blood? Where do capillaries carry blood and why? What is the function of the mouth in digestion? 103 They show the gradual change in living things over time Conditions do not always allow fossils to form Soft tissue does not easily form a fossil (it decays) Many fossils are yet to be found The similar structure suggests that the all evolved from one common ancestor An increase in mass, length or size Cell division, elongation and differentiation Cell division and differentiation A small cell in a ‘squashed disc’ shape with no nucleus to give it more space to carry oxygen on the haemoglobin it contains Large cells that fight infection by either engulfing pathogens or producing antibodies/antitoxins Fragments of cells that form clots when the skin is cut The liquid part of blood, carries other dissolved chemicals such as glucose and carbon dioxide A group of cells working together A group of tissues working together A group of organs working together Aorta, vena cava, pulmonary artery, pulmonary vein From the left ventricle to the body From the body to the right atrium From the right ventricle to the lungs From the lungs to the left atrium Left Right To prevent blood flowing in the wrong direction (backflow) The left, because it has to pump blood at higher pressure Away from the heart Towards the heart Through tissues, to exchange materials such as oxygen and carbon dioxide Mechanically break up food into a bolus, produce saliva to start digestion with enzymes and lubricate food 104 105 106 107 108 109 110 111 What is the function of the oesophagus in digestion? What is the function of the stomach in digestion? What is the function of the small intestine in digestion? What is the function of the large intestine in digestion? What is the function of the pancreas in digestion? What is the function of the liver in digestion? What is the function of the gall bladder in digestion? What is the alimentary canal? What is peristalsis 112 113 114 115 116 117 118 119 120 121 122 123 124 What enzymes break down carbohydrates and give an example What enzymes break down proteins and give two examples What enzymes break down fats? What do carbohydrates get broken down into? What do proteins get broken down into? What do fats get broken down into? What are the roles of bile? How do villi aid digestion? Which functional foods claim to improve health? How do Probiotics claim to improve health? How do Prebiotics claim to improve health? How do plant stanol esters claim to improve health? To transport the bolus to the stomach Acid kills bacteria on food and allows enzymes to work better, food is churned up Use enzymes to break down food molecules and absorb them into the blood Absorbing water Production of enzymes Production of bile Storage of bile The tube through the body from mouth to anus where digestion happens When the muscular wall of the alimentary canal squeezes and pushes food through it to help digestion Carbohydrases – amylase Proteases – pepsin and trypsin Lipases Simple sugars Amino acids Fatty acids and glycerol To emulsify fats and neutralize stomach acid They increase surface area in the gut and make absorption of nutrients more efficient Probiotics – Lactobacillus and bifidobacteria Prebiotics – oligosaccharides Plant stanol esters By adding to the bacteria in the gut By providing food for the bacteria in the gut By lowering cholesterol