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... INTRODUCTION TO NUTRITION BCH 282 (Lecture-1) Dr. Saba Abdi BCH 282 Biochemistry of Nutrition (2+0) credit-hours Topics Energy of food, and its determination. Carbohydrates Proteins and fats of diets and their physiological effects. Energy balance. Water balance and sodium and potassium output. Minerals and trace elements in diets and their regulation to prevent epidemic diseases. Vitamins and their importance. . Food poisoning. Exam Mark First CAT : 20 Marks Second CAT : 20 Marks Final : 60 Marks • • • Total = 100 marks Dr.Saba Abdi Books and References 1. Lippincott’s illustrated reviews: Biochemistry 2. Harper’s Biochemistry 3. Understanding normal and clinical nutrition : Whitney , Cataldo , Rolfes Dr.Saba Abdi What is nutrition? The science of nutrition examines the quantitative and qualitative requirements of diet necessary to maintain good health. Dr.Saba Abdi . Diet: the food and beverages a person eats and drinks. Functional Food : Food that contains physiologically active compounds that provide health benefits beyond their nutrient contributions. Energy : The capacity to do work . The energy in food is chemical energy .The body converts this chemical energy to mechanical, electrical and heat energy. Dr.Saba Abdi What is nutrient? A nutrient is a chemical substance in food that helps to maintain the body. Some provide energy. All help build/repair cells and tissues, regulate bodily processes such as breathing. Nutrients also helps to reduce the risk of some diseases. Nutrients can be grouped into 6 classes. Dr.Saba Abdi The six classes of nutrients Nutrients Inorganic nutrients Minerals Organic nutrients Water Protein Carbohydrates Dr.Saba Abdi Lipids(fats) Vitamins Carbohydrates Functions • Provides our brains and body with glucose. Characteristics • 4 calories per gram. Types of Carbohydrates • Simple and complex carbohydrates Dr.Saba Abdi Fats Functions • Carry and help with absorption of the fat-soluble vitamins A, D, E and K. • Protect organs from injury. • Regulate body temperature. • Play important role in growth and development. Characteristics • 9 calories per gram. • Saturated , unsaturated fats and trans fats. Dr.Saba Abdi Proteins-The main building blocks and repair kit for body tissue Functions • Critical for growth, maintenance and repair of • muscles, bones, blood, hair and fingernails. • Key to synthesis of enzymes, hormones, • antibodies and provide essential amino acids. Characteristics • 4 calories per gram. • 20 amino acids total; 9 essential amino acids. Dr.Saba Abdi Vitamins Functions • Help put proteins, fats, and carbohydrates to use. • Essential to regulating growth, maintaining tissue, • releasing energy from food. • Involved in the manufacture of blood cells,hormones, and other compounds. Vitamins are classified by solubility: • Fat-soluble: Vitamins A, D, E and K. •Water-soluble: B vitamins (8 total) and vitamin C Dr.Saba Abdi Minerals Functions • crucial components of enzyme systems • regulate musculoskeletal functions • responsible for nervous system transmission • facilitate blood clotting • ensure normal cardiac rhythm Characteristics: 16 minerals • Major: Sodium, potassium, chloride, calcium, phosphorus, magnesium and sulfur. . • Trace: Iron, zinc, selenium, molybdenum, iodine, Water Functions • Essential for body temperature regulation. • Transportation of nutrients and wastes in the body. • All chemical reactions. • Maintenance of blood volume. • Yields no energy Dr.Saba Abdi Macro. & Micronutrients macronutrients :The intake of these energy-rich molecules is larger than that of the other dietary nutrients. Therefore, they are called the macronutrients. Micronutrients :Those nutrients needed in lesser amounts, vitamins and minerals, are called the micronutrients. Dr.Saba Abdi . Essential nutrient: Nutrients that are either not made in body or are made in insufficient quantities, but are needed for proper functioning of body. They must be supplied to body from food. Non nutrients: Compounds present in food but do not fit within the six classes of nutrients. Such as alcohols, phytochemicals, pigments, additives. Energy yielding nutrients: carbohydrates, fats & proteins. Dr.Saba Abdi Variables which affect nutrient needs: 1. Age 2. Gender 3. Activity Level 4. Climate 5. Health Dr.Saba Abdi Dietary Reference Intakes: DRI consist of four dietary reference standards for the intake of nutrients designated for specific age groups, physiologic states, and gender Dr.Saba Abdi Estimated Average Requirement (EAR) Estimated Average Requirement (EAR): The EAR is the average daily nutrient intake level estimated to meet the requirement of one half of the healthy individuals in a particular life stage and gender group. It is useful in estimating the actual requirements in groups and individuals. Dr.Saba Abdi Recommended Dietary Allowance (RDA) • Recommended Dietary Allowance (RDA): The RDA is the average daily dietary intake level that is sufficient to meet the nutrient requirements of nearly all (97–98%) the individuals in a life stage and gender group. The RDA is not the minimal requirement for healthy individuals; rather, it is intentionally set to provide a margin of safety for most individuals. The EAR serves as the foundation for setting the RDA. If the standard deviation (SD) of the EAR Dr.Saba Abdi Adequate Intake (AI) • Adequate Intake (AI): The AI is set instead of an RDA if sufficient scientific evidence is not available to calculate an EAR or RDA. The AI is based on estimates of nutrient intake by a group (or groups) of apparently healthy people that are assumed to be adequate. For example, the AI for young infants, for whom human milk is the recommended sole source of food for the first four to six months, is based on the estimated daily mean nutrient intake supplied by human milk for healthy, full-term infants who are exclusively breast-fed. Dr.Saba Abdi Tolerable Upper Intake Level (UL) • Tolerable Upper Intake Level (UL): The UL is the highest average daily nutrient intake level that is likely to pose no risk of adverse health effects to almost all individuals in the general population. As intake increases above the UL, the potential risk of adverse effects may increase. The UL is not intended to be a recommended level of intake. The UL are useful because of the increased availability of fortified foods and the increased use of dietary supplements. The UL applies to chronic daily use. For some nutrients, there may be insufficient data on which to develop a UL. Dr.Saba Abdi The Food Guide Pyramid It is an outline of what to eat each day based on the Dietary Guidelines It's a general guide that lets you choose a healthful diet. Dr.Saba Abdi 1. 2. Aim for fitness (aim for healthy weight) Be physically active each day 3. Let the pyramid guide your choices 4. Choose a variety of grains daily, especially whole grains 5. Choose a variety of fruits and vegetables daily. 6. Keep food safe to eat. 7. Choose a diet that is low in saturated fat and cholesterol and moderate in total fat 8. Choose beverages and foods to moderate your intake of sugars 9. Choose and prepare food with less salt Dr.Saba Abdi