Download FREE Solved Full Length Mock Test Paper

C SIR NET, GA TE, IIT-JA M, UGC NET , TIFR , IISc , JEST , JNU, BHU , ISM , IBPS , C SAT, SLET, NIMCET, C TET
IIT-JAM - BIOLOGICAL SCIENCE
MOCK TEST PAPER
Attempt ALL the obj ective questions (Questions 1-100).
Each of these questions carries three marks.
1 negati ve mark for each wrong
answer.
Pattern of questions : MCQs
Total m arks
Dur ation of test
: 300
: 3 Hours
For IIT-JAM, JNU, GATE, NET, NIMCET and Other Entrance Exams
1-C-8, Sheela Chowdhary Road, Talwandi, Kota (Raj.) Tel No. 0744-2429714
Web Site www.vpmclasses.com [email protected]
Phone: 0744-2429714
Mobile: 9001297111, 9829567114, 9001297243
W ebsit e: www.vpmclasses.co m
E-Mail: vpmclasse [email protected] / inf [email protected] m
A ddress: 1-C-8, Shee la Chowdhary Road, SFS, TA LWANDI, KOTA , RAJA STHA N, 324005
Page 1
C SIR NET, GA TE, IIT-JA M, UGC NET , TIFR , IISc , JEST , JNU, BHU , ISM , IBPS , C SAT, SLET, NIMCET, C TET
1.
At the center of all 20 s tandard amino acids is what is termed the α-carbon that is
covalently bonded with four other chemical groups . Which of these four chemical
groups is not a norm al component of all amino acids ?
(A) An amino group
(B) A carboxyl group
(C) A m ethyl group
(D) (C) a s ide chain (R group)
2.
Which process does not generate CO2?
(A) The citric acid cycle
(B) The conversion of pyruvate to lactic acid
(C) The conversion of pyruvate to acetyl-CoA
(D) The conversion of pyruvate to ethanol
3.
The word, us ed for the sm all s olid s upports onto which are spotted hundreds of
thous ands of tiny drops of DNA that can be used to s creen gene express ion, is
(A) Southern blot
(B) Cloning library
(C) DNA microarrays
(D) Northern blot
4.
Protozoans called choano flagellates live in sm all clusters . They look very m uch
like choanocytes, special feeding cells found in s ponges, which are s imple anim als.
Why
might
biologists
find
choano
flagellates
of
great
evolutionary
interes t?
(A) They show how the very firs t organisms m ight have lived.
(B) They might show how the firs t heterotrophs lived.
(C) Offer hint about origin of multicell ular organism
Phone: 0744-2429714
Mobile: 9001297111, 9829567114, 9001297243
W ebsit e: www.vpmclasses.co m
E-Mail: vpmclasse [email protected] / inf [email protected] m
A ddress: 1-C-8, Shee la Chowdhary Road, SFS, TA LWANDI, KOTA , RAJA STHA N, 324005
Page 2
C SIR NET, GA TE, IIT-JA M, UGC NET , TIFR , IISc , JEST , JNU, BHU , ISM , IBPS , C SAT, SLET, NIMCET, C TET
(D) They suggest what the first eukaryotes might have been like.
5.
In a ________ habitat natality exceeds mortality and in a ______ habitat mortality
exceeds natality.
(A) Fragmented. . .hot spot
(B) Tropical. . .polar
(C) In both tropical and pola r environm ents there may be regions where with
differing rates of m ortality and natality.
(D) Natural . . .s ource
6.
The water readily available to plants for absorption by roots is
(A) Gravitational water
(B) Capillary water
(C) Rain water
(D) Hygros copic water
7.
The zoned reserve concept of landscape management calls for:
(A) Man y s m all, interconnected nature preserves .
(B) Protected areas to be s urrounded by trans itional areas .
(C) Bioremediatio n.
(D) As s isting the m ovement of individuals from a source to a s ink population.
8.
To enter or leave a cell, subs tances mus t pass through
(A) A m icrotubule.
(B) The Golgi apparatus .
(C) The nucleus.
(D) The plasm a m embrane.
9.
L-alanine and D-alanine
(A) Are pres ent in virtually all proteins .
(B) Lack an R group.
Phone: 0744-2429714
Mobile: 9001297111, 9829567114, 9001297243
W ebsit e: www.vpmclasses.co m
E-Mail: vpmclasse [email protected] / inf [email protected] m
A ddress: 1-C-8, Shee la Chowdhary Road, SFS, TA LWANDI, KOTA , RAJA STHA N, 324005
Page 3
C SIR NET, GA TE, IIT-JA M, UGC NET , TIFR , IISc , JEST , JNU, BHU , ISM , IBPS , C SAT, SLET, NIMCET, C TET
(C) Are enantiomers .
(D) Are s uper impos able is omers of each other.
10.
The enzyme that converts 3-phos phoglycerate to 2-phosphoglycerate is a
(A) Transferase.
(B) kinas e.
(C) m utase.
(D) phos phorylase
11.
Which of the following DNA sequences is not found in a typical E. coli expression
vector?
(A) A trans cription termination s equence
(B) A ribosom e-binding s ite
(C) A promoter
(D) A telomere
12.
Which of the follow does not apply to a population with a low effective population
s ize?
(A) Genetic drift.
(B) Increased genetic divers ity.
(C) Reduced heterozygos ity.
(D) Increas ed hom ozygos ity.
13.
The relative location of four genes on a chromosom e can be mapped from the
following data on crossover frequencies G Frequency of Cross over
B and D 5%
C and A 15%
A and B 30%
C and B 45%
C and D 50%
Phone: 0744-2429714
Mobile: 9001297111, 9829567114, 9001297243
W ebsit e: www.vpmclasses.co m
E-Mail: vpmclasse [email protected] / inf [email protected] m
A ddress: 1-C-8, Shee la Chowdhary Road, SFS, TA LWANDI, KOTA , RAJA STHA N, 324005
Page 4
C SIR NET, GA TE, IIT-JA M, UGC NET , TIFR , IISc , JEST , JNU, BHU , ISM , IBPS , C SAT, SLET, NIMCET, C TET
Which of the following represents the relative positions of these four genes on the
chrom os ome?
(A) ABCD
(B) ADCB
(C) CABD
(D) CBAD
14.
Species that have a dis proportionately large impact on the maintenance of an
ecos ys tems biodiversity are referred to as :
(A) E xotics
(B) Prim ary producer
(C) Archaea
(D) Keys tone s pecies
15.
A polypeptide is cleaved into peptides by treatm ent with tryps in and cyanogen
brom ide, and the peptides are purified and s equenced. The s equences of the
peptides (from N to C-terminus ) are s hown below. (Note: Trypsin cleaves after K
and R residues ; cyanogen brom ide cleaves after M.)
(A) A.T-3
(B) B.C-1
(C) D.T-4
(D) C.C-2
16.
A songbird that hears the s ongs of other species as well as its own.
Phone: 0744-2429714
Mobile: 9001297111, 9829567114, 9001297243
W ebsit e: www.vpmclasses.co m
E-Mail: vpmclasse [email protected] / inf [email protected] m
A ddress: 1-C-8, Shee la Chowdhary Road, SFS, TA LWANDI, KOTA , RAJA STHA N, 324005
Page 5
C SIR NET, GA TE, IIT-JA M, UGC NET , TIFR , IISc , JEST , JNU, BHU , ISM , IBPS , C SAT, SLET, NIMCET, C TET
(A) Will s in g the s ong of its own species , but needs practice.
(B) Will ins tinctively s ing the song of its s pecies perfectly.
(C) Will sing other songs as well as its own.
(D) Will be confused and not mas ter any s ong.
17.
The function of water in photos ynthes is is to
(A) Com bine with C0 2
(B) Abs orb light energy
(C) Supply electrons in the light-dependent reactions
(D) Transport H, ions in the light-independent (dark) reactions
18.
An e xam ple of associative learning would be:
(A) Classical conditioning
(B) Operant conditioning
(C) Pavlovian conditioning
(D) All of the above
19.
Becaus e proteins can abs orb light maxim ally at 280 nm, they can be identified and
quantified in s olution by using a s pectrophotom eter. Which of the following is true
about the absorption of light by proteins ?
(A) Proteins absorb infrared light.
(B) All amino acids absorb light equally.
(C) The greater the concentration of protein in a solution, the more 280 nm
transmitted light will be detected by a s pectrophotom eter.
(D) Abs orbance of 280 nm light by proteins increas es with the concentration of the
protein.
20.
Which technique is not normally associated with DNA fingerprinting?
(A) Res triction endonucleas e diges tion
(B) The polym erase chain reaction (PRC)
Phone: 0744-2429714
Mobile: 9001297111, 9829567114, 9001297243
W ebsit e: www.vpmclasses.co m
E-Mail: vpmclasse [email protected] / inf [email protected] m
A ddress: 1-C-8, Shee la Chowdhary Road, SFS, TA LWANDI, KOTA , RAJA STHA N, 324005
Page 6
C SIR NET, GA TE, IIT-JA M, UGC NET , TIFR , IISc , JEST , JNU, BHU , ISM , IBPS , C SAT, SLET, NIMCET, C TET
(C) DNA microarray analys is
(D) Southern blotting
21.
High value of B O D (Biochemical Oxygen Dem and) shows
(A) Water is normal
(B) Water is highly polluted
(C) Water is less polluted
(D) None of these
22.
An e xception to cell theory?
(A) Plant cell
(B) Virus
(C) Fungi
(D) Anim al cell
23.
Which of the following amino acids has a net negative charge at pH 7.0?
(A) Glycine
(B) Threonine
(C) As partate
(D) Arginine
24.
The isoelectric point, or pI, of an am ino acid or a protein is
(A) The pH at which the am ino acid or protein has no net charge.
(B) Zero at pH 7.0.
(C) The pH at which the am ino acid or protein is neither hydrophobic nor
hydrophilic.
(D) The meas ure of how hydrophobic an amino acid or protein is .
25.
Peptide bonds , which covalently link two amino acids , result from
(A) The oxidation of amino acids .
(B) The condensation of am ino acids.
Phone: 0744-2429714
Mobile: 9001297111, 9829567114, 9001297243
W ebsit e: www.vpmclasses.co m
E-Mail: vpmclasse [email protected] / inf [email protected] m
A ddress: 1-C-8, Shee la Chowdhary Road, SFS, TA LWANDI, KOTA , RAJA STHA N, 324005
Page 7
C SIR NET, GA TE, IIT-JA M, UGC NET , TIFR , IISc , JEST , JNU, BHU , ISM , IBPS , C SAT, SLET, NIMCET, C TET
(C) The hydrolysis of amino acids .
(D) Hydrogen bonds between amino acids .
26.
DNA s ynthes is takes place in which of following phas e of the cell cycle?
(A) G0
(B) G1
(C) S phas e
(D) G2 phas e
27.
What is the nomenclature for the fatty acid s hown below?
(A) 20:8(D5,6,8, 9,11, 12, 14, 15)
(B) 20:8(D6,7,9, 10,12,13,15,16)
(C) 20:4(D5,8,11, 14)
(D) 20:4(D6,9,12, 15)
28.
By what mechanism would a nonpolar m olecule move across a m embrane if it is
m oving down its concentration gradient?
(A) Facilitated diffus ion
(B) Pass ive transport
(C) Simple diffusion
(D) Acti ve trans port
29.
Presence of AIDS virus cannot be detected by(A) ELIS A
(B) Wes tern blotting
(C) Northern Blot
(D) As s ay of full-length ds DNA
Phone: 0744-2429714
Mobile: 9001297111, 9829567114, 9001297243
W ebsit e: www.vpmclasses.co m
E-Mail: vpmclasse [email protected] / inf [email protected] m
A ddress: 1-C-8, Shee la Chowdhary Road, SFS, TA LWANDI, KOTA , RAJA STHA N, 324005
Page 8
C SIR NET, GA TE, IIT-JA M, UGC NET , TIFR , IISc , JEST , JNU, BHU , ISM , IBPS , C SAT, SLET, NIMCET, C TET
30.
Hum an hemoglobin has four polypeptide subunits : two identical 16,000 molecular
weight á-chains and two identical 16,000 m olecular weight b-chains , whereas the
RNA polym eras e of influenza virus has three unique polypeptide s ubunits : PA, PB1
and PB2. Which of the following s tatements is true?
(A) Influenza virus RNA polymeras e cons ists of protom ers .
(B) Human hemoglobin and influenza virus RNA polym erase are oligom eric
proteins .
(C) Human hemoglobin and influenza virus RNA polym erase are multis ubunit
proteins .
(D) Hum an hemoglobin consists of oligopeptide s ubunits.
31.
The acrosom e of the s perm is form ed from the
(A) Mitochondria
(B) Centros om e
(C) lys os om e
(D) golgi bodies
32.
The level of protein s tructure that des cribes all as pects of the three-dim ens ional
folding of a polypeptide is referred to as the
(A) Quaternary structure.
(B) Secondary structure.
(C) Primary s tructure.
(D) Tertiary s tructure.
33.
X-ra y diffraction and nuclear magnetic resonance (NMR), two techniques used to
s olve the three-dim ensional s tructure of m olecules, differ in that
(A) N MR is lim ited to molecules that can be crys tallized.
(B) NMR is better for analyzing large proteins .
(C) Only molecules to be analyzed by NMR need to be labeled with isotopes.
Phone: 0744-2429714
Mobile: 9001297111, 9829567114, 9001297243
W ebsit e: www.vpmclasses.co m
E-Mail: vpmclasse [email protected] / inf [email protected] m
A ddress: 1-C-8, Shee la Chowdhary Road, SFS, TA LWANDI, KOTA , RAJA STHA N, 324005
Page 9
C SIR NET, GA TE, IIT-JA M, UGC NET , TIFR , IISc , JEST , JNU, BHU , ISM , IBPS , C SAT, SLET, NIMCET, C TET
(D) Only x-ra y diffraction is s uccess ful on all proteins .
34.
Which of the following experiments provided the firs t evidence that the amino acid
s equence of a polypeptide chain contains all the information required to fold the
chain into its native, three-dimensional s tructure?
(A) When ribonucleas e is treated with urea, it los es its catalytic activity.
(B) When denatured ribonuclease is allowed to renature, it regains its catalytic
activity.
(C) When renatured ribonuclease is allowed to denature, it regains its catalytic
activity.
(D) Addition of mercaptoethanol caus es ribonucleas e to regain catalytic activity.
35.
Two or more proteins that have little s equence s imilarity, but s hare the sam e major
s tructural motif and have functional sim ilarities , belong to the s ame
(A) Fold.
(B) Fam ily.
(C) s uper fam ily.
(D) Motif.
36.
Below are the s tandard reduction potentials
for two conjugate redox pair:
Pyru vate-/lactateNAD+/NADH
Which of the following is true?
(A) The pyru vate/lactate conjugate redox pair has a greater tendency to los e
electrons than the NAD+ /NADH redox pair.
(B) Pyru vate has a greater affinity for electrons than NAD+ .
(C) NAD + is a reducing agent.
Phone: 0744-2429714
Mobile: 9001297111, 9829567114, 9001297243
W ebsit e: www.vpmclasses.co m
E-Mail: vpmclasse [email protected] / inf [email protected] m
A ddress: 1-C-8, Shee la Chowdhary Road, SFS, TA LWANDI, KOTA , RAJA STHA N, 324005
Page 10
C SIR NET, GA TE, IIT-JA M, UGC NET , TIFR , IISc , JEST , JNU, BHU , ISM , IBPS , C SAT, SLET, NIMCET, C TET
(D) Under s tandard conditions, NAD+ is m ore likely to be converted to NADH, than
pyruvate is to converted to lactate.
37.
The Hs p70 m olecular chaperone proteins are m ore abundant in cells s tress ed by
elevated temperatures because
(A) Hs p70 is needed to unfold proteins denatured by heat.
(B) Hs p70 is needed to des troy proteins denatured by heat.
(C) Hsp70 is needed to s timulate the aggregation of proteins denatured by heat.
(D) Hsp70 is needed to protect proteins that have been denatured by heat.
38.
Steroid hormones
(A) Bind cell s urface receptors.
(B) Are ins oluble in blood.
(C) Have a very rapid effect (within seconds ) on target cells .
(D) Mediate their effects through s econd mess engers .
39.
Hydrogen bonds between amino acids in a polypeptide occur between which
chem ical groups?
(A) The C=O and C-H groups
(B) The C=O and C-R groups
(C) The C=O groups
(D) The C=O and N-H groups
40.
Proline res idues are mos t likely to occur in which of the following s econdary
s tructures?
(A) An α helix
(B) A β turn
(C) A β s heet
(D) A coiled
Phone: 0744-2429714
Mobile: 9001297111, 9829567114, 9001297243
W ebsit e: www.vpmclasses.co m
E-Mail: vpmclasse [email protected] / inf [email protected] m
A ddress: 1-C-8, Shee la Chowdhary Road, SFS, TA LWANDI, KOTA , RAJA STHA N, 324005
Page 11
C SIR NET, GA TE, IIT-JA M, UGC NET , TIFR , IISc , JEST , JNU, BHU , ISM , IBPS , C SAT, SLET, NIMCET, C TET
41.
Which of the following is true about sickle-cell anemia?
(A) People with s ickle-cell anem ia have inherited one or more alleles for sickle-cell
hemoglobin.
(B) People with sickle-cell anemia have norm al levels of hemoglobin and norm al
numbers of erythrocytes .
(C) People with sickle-cell anemia have sickle-cell hemoglobin m olecules that form
insoluble fibers .
(D) People with s ickle-cell anem ia have a mutation in either the α or β hemoglobin
chains .
42.
Which of the following is true about the s tructure of all immunoglobulins?
(A) The chains are linked by dis ulphide bonds .
(B) They cons is t of two heavy chains and two light chains .
(C) The five class es of imm unoglobulins each have their own characteris tic type of
light chain.
(D) An antigen-binding s ite is form ed by the combination of two heavy chains.
43.
Com plete β-oxidation of a 16-carbon s aturated fatty acid
(A) Generates eight m olecules of NADH.
(B) Requires eight β-oxidation cycles.
(C) Generates eight molecules of FADH 2.
(D) Generates eight molecules of acetyl-CoA
44.
During s keletal mus cle contraction, which of the following narrows ?
(A) The I band
(B) The Z dis k
(C) The A band
Phone: 0744-2429714
Mobile: 9001297111, 9829567114, 9001297243
W ebsit e: www.vpmclasses.co m
E-Mail: vpmclasse [email protected] / inf [email protected] m
A ddress: 1-C-8, Shee la Chowdhary Road, SFS, TA LWANDI, KOTA , RAJA STHA N, 324005
Page 12
C SIR NET, GA TE, IIT-JA M, UGC NET , TIFR , IISc , JEST , JNU, BHU , ISM , IBPS , C SAT, SLET, NIMCET, C TET
(D) The M line
45.
Which of the following is true about the difference between oxidative
phos phorylation and photophos phorylation?
(A) Photophos phorylation occurs only in photosynthetic organisms and oxidative
phos phorylation occurs only in non-photos ynthetic organisms .
(B)In oxidative phosphorylation, NADH donates electrons ; in photophos phorylation
NADPH donates electrons .
(C) Photophos phorylation occurs only in light; oxidative phos phorylation occurs
only in darkness.
(D) In oxidative phosphorylation, O2 is reduced to H 2O; in photophosphorylation,
H 2O is oxidized to O2 .
46.
The num ber of ATP required for urea s ynthes is is :
A) 0
(B) 1
(C) 2
(D) 3
47.
Why are concerns about the individuality of clones s cientifically ques tio nable?
(A) Identical twins have very different personalities , and they are ess entially clones
of each other
(B) Clones of plants are m ade all the tim e when gardeners grow new plants from
cuttings
(C) The environment and not the genes is the major s haper of the pers onality
(D) No clone would ever want to be exactly the s am e as his parent
48.
Which of the following is true about the role of ATP during s keletal mus cle
contraction?
Phone: 0744-2429714
Mobile: 9001297111, 9829567114, 9001297243
W ebsit e: www.vpmclasses.co m
E-Mail: vpmclasse [email protected] / inf [email protected] m
A ddress: 1-C-8, Shee la Chowdhary Road, SFS, TA LWANDI, KOTA , RAJA STHA N, 324005
Page 13
C SIR NET, GA TE, IIT-JA M, UGC NET , TIFR , IISc , JEST , JNU, BHU , ISM , IBPS , C SAT, SLET, NIMCET, C TET
(A) After h ydrolys is of ATP at the m yosin head, Pi and ADP are imm ediately
released.
(B) The release of Pi from myosin is needed for the "power s troke" that caus es
filam ent sliding.
(C) Binding of ATP caus es the m yosin head to bind actin filaments .
(D) The hydrolys is of ATP at the myosin head caus es m yosin to tightly bind the
next actin s ubunit
49.
Which of the following is true of cyclin-dependent kinas es (CDKs )?
(A) They are inactivated by binding to cyclin.
(B) Their activity changes throughout the cell cycle.
(C) They are degraded as a res ult of addition of ubiquitin.
(D) They alter the activity of c yclins .
50.
Which of the following binding cons tants represents the highes t affinity?
(A) K a = 1.0 × 107 M–1
(B) Kd = 1.0 × 10–9 M
(C) Kd = 1.5 × 10–9 M
(D) Ka = 2.0 × 108 M–1
51.
How does hem oglobin bind O2 cooperatively?
(A) The binding of one m olecule of O2 to one s ubunit of hem oglobin enhances the
assem bly of other s ubunits to form a com plete hemoglobin protein.
(B) The binding of one molecule of O2 to one hem oglobin protein enhances the
binding of a m olecule of O2 to a different hemoglobin protein.
Phone: 0744-2429714
Mobile: 9001297111, 9829567114, 9001297243
W ebsit e: www.vpmclasses.co m
E-Mail: vpmclasse [email protected] / inf [email protected] m
A ddress: 1-C-8, Shee la Chowdhary Road, SFS, TA LWANDI, KOTA , RAJA STHA N, 324005
Page 14
C SIR NET, GA TE, IIT-JA M, UGC NET , TIFR , IISc , JEST , JNU, BHU , ISM , IBPS , C SAT, SLET, NIMCET, C TET
(C) The binding of one molecule of O2 to one subunit of hem oglobin enhances the
affinity of the s ame s ubunit for m ore m olecules of O2 .
(D) The binding of one molecule of O2 to one subunit of hem oglobin enhances the
affinity of other subunits for O2 .
52.
What is the role of cytoto xic T cells (TC) in the immune response?
(A) The y produce cytokines and interleukins that s timulate the proliferation of
immune cells .
(B) They produce immunoglobulins (antibodies ) that bind bacteria or viruses and
target them for des truction.
(C) They des troy virally infected cells to which they are complexed through their Tcell receptors .
(D) They inges t large particles and cells by phagocytos is.
53.
What is the biological advantage to the s igmoidal binding curve of hemoglobin for
oxygen?
(A) It ens ures that hemoglobin has a high affinity for o xygen.
(B) It allows hemoglobin to bind oxygen irrevers ibly.
(C) It ensures that hemoglobin can bind oxygen only weakly.
(D) It allows hemoglobin to s hift between low and high affinities for oxygen.
54.
Which of the following is true about the T (tens e) → R (relaxed) transition of
hemoglobin?
(A) The T s tate of hemoglobin binds oxygen with a higher affinity than the R s tate.
(B) The binding of O2 to a s ubunit in the T s tate can cause the transition of other
s ubunits to the R s tate.
(C) The T s tate has a narrower pocket between &946; s ubunits than does the R
s tate.
Phone: 0744-2429714
Mobile: 9001297111, 9829567114, 9001297243
W ebsit e: www.vpmclasses.co m
E-Mail: vpmclasse [email protected] / inf [email protected] m
A ddress: 1-C-8, Shee la Chowdhary Road, SFS, TA LWANDI, KOTA , RAJA STHA N, 324005
Page 15
C SIR NET, GA TE, IIT-JA M, UGC NET , TIFR , IISc , JEST , JNU, BHU , ISM , IBPS , C SAT, SLET, NIMCET, C TET
(D) When hem oglobin undergoes the T →
R trans ition, the s tructures of the
individual s ubunits change dram atically.
55.
Higher alcohol pres ent in waxes is :
(A) Ben zyl
(B) Meth yl
(C) Ethyl
(D) Cetyl
56.
Which of the following is not a function of hem oglobin?
(A) It delivers O2 to peripheral tiss ues .
(B) It removes CO2 from peripheral tiss ues.
(C) It delivers CO2 to the lungs .
(D) It delivers H + to peripheral tiss ues .
57.
The Bohr effect, the effect of pH and CO2 concentration on the binding and releas e
of oxygen by hemoglobin, dictates that
(A) Oxygen binds hem oglobin better at low pH.
(B) Oxygen and H + are bound at the sam e sites in hem oglobin.
(C) The binding of CO2 is invers ely related to the binding of oxygen.
(D) The binding of CO2 is invers ely related to the binding of H+.
58.
Uns aturated fatty acid found in the cod liver oil and containing 5 double bonds is :
(A) Clupanodonic acid
(B) Cervonic acid
(C) Elaidic acid
(D) Tim nodonic acid
59.
Differentiate the following equation us ing the s tandard rules :
Phone: 0744-2429714
Mobile: 9001297111, 9829567114, 9001297243
W ebsit e: www.vpmclasses.co m
E-Mail: vpmclasse [email protected] / inf [email protected] m
A ddress: 1-C-8, Shee la Chowdhary Road, SFS, TA LWANDI, KOTA , RAJA STHA N, 324005
Page 16
C SIR NET, GA TE, IIT-JA M, UGC NET , TIFR , IISc , JEST , JNU, BHU , ISM , IBPS , C SAT, SLET, NIMCET, C TET
(A)
(B)
(C)
(D)
60.
A sim ple plot of V0 vers us [S] is s uperior to a double-reciprocal plot (1/Vo vers us
1/[S]) if you are trying to
(A) Determine Vmax.
(B) Detect allos teric regulation.
(C) Determine the type of inhibition.
(D) Determine the Km.
61.
In competitive inhibition, increas ing concentrations of the inhibitor will have the
following effect on the kinetics of the enzyme:
(A) K m will decreas e.
(B) Vmax will s tay the s ame.
(C) The reaction will ceas e becaus e the inhibitor binds irrevers ibly.
(D) Km / Vmax will s tay the s ame.
62.
Which of the following is a s tructural polysaccharide in plant cells ?
(A) gl ycogen
(B) am ylos e
(C) s tarch
Phone: 0744-2429714
Mobile: 9001297111, 9829567114, 9001297243
W ebsit e: www.vpmclasses.co m
E-Mail: vpmclasse [email protected] / inf [email protected] m
A ddress: 1-C-8, Shee la Chowdhary Road, SFS, TA LWANDI, KOTA , RAJA STHA N, 324005
Page 17
C SIR NET, GA TE, IIT-JA M, UGC NET , TIFR , IISc , JEST , JNU, BHU , ISM , IBPS , C SAT, SLET, NIMCET, C TET
(D) cellulos e
63.
(A)
(B)
(C)
(D)
64.
Which is the s afes t and mos t effective way to develop a vaccine that would protect
the recipient if expos ed to the natural toxin of Vibrio cholerae, the bacterium that
caus es cholera.
(A) Us e purified natural toxin as a vaccine to elicit an immune res ponse.
(B) Us e live toxin-bearing Vibrio cholerae as a vaccine to elicit an immune
response.
(C) Us e a genetically engineered vers ion of the cholera toxin with an altered
carbohydrate-binding site.
(D) Us e a genetically engineered version of the cholera toxin lacking the
carbohydrate-binding site as a vaccine to elicit an imm une res pons e.
65.
Treatm ent of gram -positive bacteria with penicillin will have what effect?
(A) It will inhibit cell wall s ynthesis by hydrolyzing the (α1 →4) bonds that connect
the carbohydrate res idues of the cell wall peptidoglycan.
Phone: 0744-2429714
Mobile: 9001297111, 9829567114, 9001297243
W ebsit e: www.vpmclasses.co m
E-Mail: vpmclasse [email protected] / inf [email protected] m
A ddress: 1-C-8, Shee la Chowdhary Road, SFS, TA LWANDI, KOTA , RAJA STHA N, 324005
Page 18
C SIR NET, GA TE, IIT-JA M, UGC NET , TIFR , IISc , JEST , JNU, BHU , ISM , IBPS , C SAT, SLET, NIMCET, C TET
(B) It will inhibit synthesis of lipopolysaccharides in the outer m embrane.
(C) It will inhibit cell wall s ynthesis by preventing the synthesis of peptide crosslinks in the cell wall peptidoglycan.
(D) It will have no effect on gram -positive bacteria; it is specific to gram -negative
bacteria.
66.
Which of the following is true about reducing ends?
(A) All polys accharides have an equal number of reducing ends as nonreducing
ends .
(B) Polys accharides grow in the direction of the nonreducing end.
(C) Dis accharides are named s tarting with the reducing end.
(D) All disaccharides have one reducing end.
67.
What role do lectins play in the infection of hos t cells by influenza virus?
(A) A plasm a mem brane lectin on the host cell binds the carbohydrate m oiety on
an influenza virus glycoprotein.
(B) Lectins present inside the cell target influenza virus es for trans fer to the
lysos om e.
(C) An influenza virus lectin binds to the carbohydrate moiety on glycoproteins on
the hos t cell s urface.
(D) An influenza virus lectin binds to the carbohydrate moiety on glycolipids on the
host cell surface.
68.
Which of the following is true about the difference between nucleotides and
nucleos ides ?
(A) Nucleotides lack a nitrogenous bas e.
(B) Nucleosides lack a ribose sugar.
(C) Nucleotides lack a phosphate.
(D) Nucleos ides lack a phos phate.
Phone: 0744-2429714
Mobile: 9001297111, 9829567114, 9001297243
W ebsit e: www.vpmclasses.co m
E-Mail: vpmclasse [email protected] / inf [email protected] m
A ddress: 1-C-8, Shee la Chowdhary Road, SFS, TA LWANDI, KOTA , RAJA STHA N, 324005
Page 19
C SIR NET, GA TE, IIT-JA M, UGC NET , TIFR , IISc , JEST , JNU, BHU , ISM , IBPS , C SAT, SLET, NIMCET, C TET
69.
The chemical s ynthes is of DNA
(A) Occurs in a 5’ to 3’ direction.
(B) Is carried out with the growing s trand attached to a solid s upport.
(C) Can add one or m ore nucleotides per chemical cycle.
(D) Requires a DNA template.
70.
If a chemical reaction starts with 1M concentrations each of reactants A and B and
products C and D, under what conditions of K’ eq and ∆G’° will the reaction
proceed in the forward direction (∆G’° = –RT ln K’ eq)?
(A) If K’ eq is greater than 1 and ∆G’° is negative.
(B) If K’ eq is 0 and ∆G’° is negative.
(C) If K’ eq is negative and ∆G’° is negative.
(D) If K’ eq is less than 1 and ∆G’° is pos itive.
71.
Deoxyribonucleic acid (DNA) is different from ribonucleic acid (RNA) in that
(A) DN A contains a 3’ H, whereas RNA contains a 3’ OH.
(B) Only DN A utilizes the bas e uracil.
(C) Only RNA can be hydrolyzed by alkaline conditions .
(D) Only DN A contains a pentos e s ugar.
72.
"Chargaff's rules" about the composition of bas es in DNA dictates that
(A) The sum of purine res idues m ust equal the s um of pyrimidine res idues .
(B) The sum of A-T base pairs m us t equal the s um of G-C bas e pairs .
(C) The bas e com pos ition of DNA is the sam e in all s pecies .
(D) DNA s pecimens isolated from different tiss ues of the sam e species vary in
base compos ition
73.
DNA can be s equenced by the Sanger m ethod in which
Phone: 0744-2429714
Mobile: 9001297111, 9829567114, 9001297243
W ebsit e: www.vpmclasses.co m
E-Mail: vpmclasse [email protected] / inf [email protected] m
A ddress: 1-C-8, Shee la Chowdhary Road, SFS, TA LWANDI, KOTA , RAJA STHA N, 324005
Page 20
C SIR NET, GA TE, IIT-JA M, UGC NET , TIFR , IISc , JEST , JNU, BHU , ISM , IBPS , C SAT, SLET, NIMCET, C TET
(A) Radioactively labeled DNA is s ubjected to four s ets of base-s pecific cleavage
reactions.
(B) Automated sequencing can be done us ing different fluores cent-labeled 2’
deoxynucleotides .
(C) The required DNA synthesis is performed via autom ated chem ical s ynthes is .
(D) The sequence can be read by a las er beam
74.
Which of the following is true concerning a DNA double helix found inside cells ?
(A) The backbone is pos itively charged.
(B) The bases are expos ed through the m ajor groove.
(C) Guanine forms two hydrogen bonds with cytosine.
(D) Adenine forms two hydrogen bonds with cytosine.
75.
Mes senger RNAs (m RNAs )
(A) Are the m olecules that s tore genetic inform ation.
(B) Specify the am ino acid s equences in polypeptide chains .
(C) Can code for only one polypeptide.
(D) Cons is t s olely of protein-coding sequence.
76.
Calculate the value of è in degrees given that:
(A) 60 0
(B) 49.6 0
(C) 0.52 0
(D) 30 0
77.
When dNTPs become depleted in the cell, which of the following enzymes will
regenerate dNTPs from dNDPs?
Phone: 0744-2429714
Mobile: 9001297111, 9829567114, 9001297243
W ebsit e: www.vpmclasses.co m
E-Mail: vpmclasse [email protected] / inf [email protected] m
A ddress: 1-C-8, Shee la Chowdhary Road, SFS, TA LWANDI, KOTA , RAJA STHA N, 324005
Page 21
C SIR NET, GA TE, IIT-JA M, UGC NET , TIFR , IISc , JEST , JNU, BHU , ISM , IBPS , C SAT, SLET, NIMCET, C TET
(A) nucleoside diphos phate kinase
(B) polyphos phate kinase
(C) creatine kinas e
(D) adenylate kinas e
78.
What is 270° in radians ?
(A)
(B)
(C)
(D)
79.
The function of macrophages is to(A) En zyme Secretion
(B) Engulf Cell organell es
(C) Engulf Foreign Material
(D) Kills Invading Bacteria
80.
Extra nuclear genetic material is found(A) Ribosome
(B) ER
(C) Chloroplas t
(D) Centriole
Phone: 0744-2429714
Mobile: 9001297111, 9829567114, 9001297243
W ebsit e: www.vpmclasses.co m
E-Mail: vpmclasse [email protected] / inf [email protected] m
A ddress: 1-C-8, Shee la Chowdhary Road, SFS, TA LWANDI, KOTA , RAJA STHA N, 324005
Page 22
C SIR NET, GA TE, IIT-JA M, UGC NET , TIFR , IISc , JEST , JNU, BHU , ISM , IBPS , C SAT, SLET, NIMCET, C TET
81.
A C3 m us tard plant was grown at 300 ppm of CO2 in 14 h light and 10 h dark
cycles , it was trans ferred to 1000 ppm CO2. This will lead to (other environmental
param eters remaining identical)(A) Increased photos ynthesis
(B) Decreas ed Photos ynthes is
(C) Increas e in Res piration
(D) No Change
82.
Loss of water from the s tom ata of leaves are known as
(A) Guttation
(B) Exudation
(C) Transpiration
(D) Evaporation
83.
During rainy s eas on wooden doors are difficult to open or clos ure becaus e of
(A) Plas molys is
(B) Im bibition
(C) Osm os is
(D) Diffusion
84.
Plasm olysis occurs due to
(A) Abs orption
(B) Os mos is
(C) Endoosmos is
(D) Exos mos is
85.
Acti ve uptake of m inerals by roots mainly depends on the
(A) Availability of oxygen
Phone: 0744-2429714
Mobile: 9001297111, 9829567114, 9001297243
W ebsit e: www.vpmclasses.co m
E-Mail: vpmclasse [email protected] / inf [email protected] m
A ddress: 1-C-8, Shee la Chowdhary Road, SFS, TA LWANDI, KOTA , RAJA STHA N, 324005
Page 23
C SIR NET, GA TE, IIT-JA M, UGC NET , TIFR , IISc , JEST , JNU, BHU , ISM , IBPS , C SAT, SLET, NIMCET, C TET
(B) Tem perature
(C) Light
(D) Availability of CO 2
86.
The hormone which signals the closure of stomata is
(A) Au xins
(B) Cytokinine
(C) Gibberelline
(D) Abs cisic acid
87.
What is the action spectrum of transpiration?
(A) Orange and red
(B) Green and ultraviole t
(C) Blue and red
(D) None of these
88.
Transpiration is leas t in
(A) High atm os pheric hum idity
(B) good soil mois ture
(C) high wind velocity
(D) dry environment
89.
Water absorption takes place through
(A) Lateral roots
(B) Root cap
(C) Root hairs
(D) Tap root
90.
Which aspect of mitos is is affected by colchicine in inducing polyploidy?
(A) DN A duplication
Phone: 0744-2429714
Mobile: 9001297111, 9829567114, 9001297243
W ebsit e: www.vpmclasses.co m
E-Mail: vpmclasse [email protected] / inf [email protected] m
A ddress: 1-C-8, Shee la Chowdhary Road, SFS, TA LWANDI, KOTA , RAJA STHA N, 324005
Page 24
C SIR NET, GA TE, IIT-JA M, UGC NET , TIFR , IISc , JEST , JNU, BHU , ISM , IBPS , C SAT, SLET, NIMCET, C TET
(B) Spindle formation
(C) Cell plate form ation
(D) Chromosome doubling
91.
A cell divides every one m inute. At this rate of divis ion it can fill a 100 m l of beaker
in one hour. How m uch time does it take to fill a 50 m l beaker?
(A) 30 m inutes
(B) 60 m inutes
(C) 59 minutes
(D) one minute
92.
Num ber of m itotic divisions required to produce 128 cells from a s ingle cell is
(A) 7
(B) 8
(C) 16
(D) 32
93.
To initiate translation of m -RNA in eukaryotes , all of the following factors are
required except :
(A) adenos ine and guanos ine triphosphates
(B) eukaryotic initiation factors
(C) form yl m ethionine-t-RNA
(D) m -RNA with the triplet AUG near the 5’ end
94.
Biogas is
(A) Methane rich fuel
(B) eco friendly and pollution free s ource
(C) Propane rich fuel
(D) Both A and C
95.
Enzym e imm obilization is
Phone: 0744-2429714
Mobile: 9001297111, 9829567114, 9001297243
W ebsit e: www.vpmclasses.co m
E-Mail: vpmclasse [email protected] / inf [email protected] m
A ddress: 1-C-8, Shee la Chowdhary Road, SFS, TA LWANDI, KOTA , RAJA STHA N, 324005
Page 25
C SIR NET, GA TE, IIT-JA M, UGC NET , TIFR , IISc , JEST , JNU, BHU , ISM , IBPS , C SAT, SLET, NIMCET, C TET
(A) Convers ion of an active enzym e into inactive form
(B) Providing enzym e with protective covering
(C) Changing a soluble enzyme into ins oluble s tate
(D) Changing pH s o that enzym e is not able to carry out its function
96.
Hum uline is
(A) Carbohydrate
(B) Protein
(C) Fat
(D) Antibiotics
97.
Which category of hypersens itivity BEST des cribes hem olytic diseas e of the
newborn caused by Rh incompatibility?
(A) atopic or anaphylactic
(B) cytotoxic
(C) immune complex
(D) delayed
98.
Which one of the following s tatements concerning imm unoglobulin allotypes is
CORRECT?
(A) Allotypes are found only on heavy chains .
(B) Allotypes are determined by class I MHC genes .
(C) Allotypes are confined to the variable regions .
(D) Allotypes are due to genetic polym orphism within a species.
99.
The class of immunoglobulin pres ent in highes t concentration in the blood of a
human newborn is
(A) IgG.
(B) IgM.
(C) IgA.
Phone: 0744-2429714
Mobile: 9001297111, 9829567114, 9001297243
W ebsit e: www.vpmclasses.co m
E-Mail: vpmclasse [email protected] / inf [email protected] m
A ddress: 1-C-8, Shee la Chowdhary Road, SFS, TA LWANDI, KOTA , RAJA STHA N, 324005
Page 26
C SIR NET, GA TE, IIT-JA M, UGC NET , TIFR , IISc , JEST , JNU, BHU , ISM , IBPS , C SAT, SLET, NIMCET, C TET
(D) IgD.
100.
AIDS is caus ed by a hum an retrovirus that kills
(A) B lym phocytes .
(B) lym phocyte stem cells .
(C) CD4-pos itive T lymphocytes .
(D) CD8-pos itive T lymphocytes
ANSWER KEY
Que stion
Answer
Que stion
Answer
Que stion
Answer
Que stion
Answer
Que stion
Answer
1.(D)
1
D
21
C
41
C
61
B
81
A
2
B
22
B
42
A
62
D
82
C
3
C
23
C
43
D
63
A
83
B
4
C
24
A
44
A
64
D
84
D
5
D
25
B
45
D
65
C
85
A
6
B
26
C
46
D
66
B
86
D
7
A
27
C
47
A
67
C
87
C
8
D
28
C
48
B
68
D
88
A
9
C
29
D
49
C
69
B
89
C
10
C
30
C
50
B
70
A
90
B
11
D
31
D
51
D
71
C
91
C
12
B
32
D
52
C
72
A
92
A
13
C
33
C
53
D
73
D
93
A
14
D
34
B
54
B
74
B
94
D
15
B
35
C
55
D
75
B
95
B
16
B
36
B
56
D
76
D
96
B
17
D
37
D
57
D
77
A
97
D
18
D
38
B
58
A
78
A
98
D
19
D
39
D
59
B
79
C
99
A
20
C
40
B
60
B
80
C
100
C
Not all amino acids have a methyl group bonded to the α-carbon. Only alanine has
a methyl group that is its s ide chain. In addition to having a side chain group, all
amino acids have a carboxyl group, an am ino group, and a hydrogen atom
covalently bonded to the α-carbon.
2.(B)
Under anaerobic conditions , pyruvate (a 3-carbon m olecule) is converted to lactic
acid (a 3-carbon m olecule) and no CO2 is generated.
Phone: 0744-2429714
Mobile: 9001297111, 9829567114, 9001297243
W ebsit e: www.vpmclasses.co m
E-Mail: vpmclasse [email protected] / inf [email protected] m
A ddress: 1-C-8, Shee la Chowdhary Road, SFS, TA LWANDI, KOTA , RAJA STHA N, 324005
Page 27
C SIR NET, GA TE, IIT-JA M, UGC NET , TIFR , IISc , JEST , JNU, BHU , ISM , IBPS , C SAT, SLET, NIMCET, C TET
3.(C)
DNA m icro arrays is the technique to analyze express ion of the thousand genes at
s ame time
4.(C)
Choanocytes bear more than a pass ing res em blance to Choanoflagellates , and
demons trate key s teps in the evolution of anim als . Scientis t Nicole King helped to
es tablish
the
dis tinction.
DNA
s equencing
indicates
that
m ulticellular
choanoflagellates and poriferans are s is ter groups, both des cended from the s am e
eukaryotic clade.
5.(D)
There are a number of models des cribing population s tructure, m any of which have
the capacity to incorporate spatial habitat effects. One such model is the sources ink m odel, that des cribes a s ys tem where some habitats have a natality that is
higher than m ortality (s ource) and others have a mortality that exceeds natality
(s ink)
6.(B)
Capillary water holded in spaces is readily available for root hairs for abs orption
7.(A)
Zoned reserves are important to preserve habitats from hum an developm ent. This
basically m eans that they stop people from harm ing natural environm ents by
preventing them from building in those habitats .
8.(D)
The cell m embrane or plasma m embrane is a biological mem brane that
s eparates the interior of all cells from the outside environm ent. The cell
m embrane is s electively permeable to ions and organic molecules and
controls the m ovement of s ubs tances in and out of cells .
9.(C)
The L- and D-stereoisomer forms of am ino acids are enantiom ers , which means
that they are nonsuperim posable mirror images of each other. Alanine, like all
amino acids beside glycine, has an a-carbon atom to which four different groups
are attached and therefore has a chiral center. Molecules with chiral centers have
s tereois omers (e. g., L-alanine and D-alanine) that are enantiom ers-is om ers that
are nonsuperim posable mirror im ages of each other
Phone: 0744-2429714
Mobile: 9001297111, 9829567114, 9001297243
W ebsit e: www.vpmclasses.co m
E-Mail: vpmclasse [email protected] / inf [email protected] m
A ddress: 1-C-8, Shee la Chowdhary Road, SFS, TA LWANDI, KOTA , RAJA STHA N, 324005
Page 28
C SIR NET, GA TE, IIT-JA M, UGC NET , TIFR , IISc , JEST , JNU, BHU , ISM , IBPS , C SAT, SLET, NIMCET, C TET
10.(C) Mutas es are a s ubclass of isom eras es that catalyze the trans fer of a functional
group from one pos ition to another in the s am e molecule. Phosphoglycerate
m utase catalyzes the trans fer of a phosphoryl group from 3-phos phoglycerate to
generate 2-phosphoglycerate
11.(D) Telom eres , which are needed to maintain yeas t artificial chromos omes (YACs ), are
not found in a typical E. coli express ion vector. A typical E. coli expression vector
contains a promoter, a ribosom e-binding s ite, and a transcription termination
s equence.
12.(B) Genetic diversity is s tudied and is applicable to large population s ize.
13.(C) Based on dis tance between the genes constructed,
14.(D) A ke ys tone s pecies is a s pecies that has a dis proportionately large effect on its
environment relative to its abundance. Such species play a critical role in
m aintaining the s tructure of an ecological comm unity, affecting m any other
organisms in an ecos ys tem and helping to determ ine the types and numbers of
various other species in the comm unity.
15.(B) C-1 or T-2 could be N-term inal peptides becaus e they overlap at their N-term inal
ends .
16.(B) Birds expos ed to s ongs of a different s pecies do not s tart im itating that s ong. Ins tead
they s eem to know to only im itate s ongs com ing from s pecifics . They have the
ability to dis criminate between s ongs of their own s pecies and those of other
s pecies .
Phone: 0744-2429714
Mobile: 9001297111, 9829567114, 9001297243
W ebsit e: www.vpmclasses.co m
E-Mail: vpmclasse [email protected] / inf [email protected] m
A ddress: 1-C-8, Shee la Chowdhary Road, SFS, TA LWANDI, KOTA , RAJA STHA N, 324005
Page 29
C SIR NET, GA TE, IIT-JA M, UGC NET , TIFR , IISc , JEST , JNU, BHU , ISM , IBPS , C SAT, SLET, NIMCET, C TET
17.(D) Photolys is of water in light reaction res ults in formation of protons and electrons
that are directed in formation of ATP and NADPH. That are used in fixation of CO2
in dark reactions
18.(D) As sociative learning is the process by which an ass ociation between two s tim uli or
a behavior and a s timulus is learned. The two forms of associative learning are
class ical and operant conditioning.
19.(D) The abs orbance of light by the s ample is directly proportional to the concentration
of the protein
20.(C) DNA m icroarrays , used only to look at RNA express ion patterns , are not us ed in
DNA
fingerprinting.
DNA
fingerprinting
norm ally
us es
PCR,
restriction
endonucleas e diges tion and southern blotting to detect genetic differences
between individuals
21.(C) BOD repres ents that high demand for oxygen and water ins ide is less polluted
22.(B) Virus is not having mass of protoplasm containing nucleus s urrounded by plasm a
m embrane, it is not living. But, it has genetic m aterial that could reproduce it.
Hence it an exception to cell theory.
23.(C) As partate (as partic acid) has a negatively charged R group and is thus negatively
charged at pH 7.0
24.(A) Amino acids and proteins have a characteris tic pH at which the molecule has no
net charge. This value is a function of all of the ionizable groups (the carboxyl
group, amino group, and certain functional groups) on the amino acids.
25.(B) A peptide bond is formed by rem oval of the elements of water (dehydration) from
the á-carboxyl group of one amino acid with the á-amino group of another.
26.(C) DNA replication is not taking place in S-phase of cell cycle.
Phone: 0744-2429714
Mobile: 9001297111, 9829567114, 9001297243
W ebsit e: www.vpmclasses.co m
E-Mail: vpmclasse [email protected] / inf [email protected] m
A ddress: 1-C-8, Shee la Chowdhary Road, SFS, TA LWANDI, KOTA , RAJA STHA N, 324005
Page 30
C SIR NET, GA TE, IIT-JA M, UGC NET , TIFR , IISc , JEST , JNU, BHU , ISM , IBPS , C SAT, SLET, NIMCET, C TET
27.(C) There are 20 carbon atoms in the fatty acid s hown above, with 4 double bonds
between C-5 and C-6, C-8 and C-9, C-11 and C-12, and C-14 and C-15 (C-1 being
the carboxyl carbon). Therefore, the correct nomencla ture for this fatty acid is
20:4(D 5,8,11, 14).
28.(C) Mem branes are impermeable to mos t polar or charged s olutes , but permeable to
nonpolar compounds . Therefore, as long as the nonpola r m olecule moving across
a mem brane is m oving down its concentration gradient, it will do s o by s imple
diffusion.
29.(D) Presence of AIDS virus detected by both the ELISA and western or northern blot
but not ass ay of full-length ds DNA
30.(C) Both proteins are m ultisubunit proteins because they consis t of two or m ore
polypeptides . The individual polypeptide chains in a multisubunit protein may be
identical or different.
31.(D) Acros om e of the s perm help in penentration of the egg during fertil ization,It is a
cap-like structure derived from the Golgi apparatus
32.(D) All aspects of the three-dim ensional folding of a polypeptide is des cribed by tertiary
s tructure
33.(C) Only certain isotopes , s uch as 1H,
13
C,
15
N,
19
F, and
31
P , poss ess the kind of
nuclear spin needed to produce a detectable NMR s ignal.
34.(B) The only information that specified the correct folding of the protein back to its
native, catalytically active s tate was its am in o acid sequence.
35.(C) Proteins and protein families belong to the same superfamily if they share little
s equence s im ilarity, but have the s ame major s tructural motif and are functionally
Phone: 0744-2429714
Mobile: 9001297111, 9829567114, 9001297243
W ebsit e: www.vpmclasses.co m
E-Mail: vpmclasse [email protected] / inf [email protected] m
A ddress: 1-C-8, Shee la Chowdhary Road, SFS, TA LWANDI, KOTA , RAJA STHA N, 324005
Page 31
C SIR NET, GA TE, IIT-JA M, UGC NET , TIFR , IISc , JEST , JNU, BHU , ISM , IBPS , C SAT, SLET, NIMCET, C TET
36.(B) The s tandard reduction potential is a measure of the affinity of the electron
acceptor of each redox pair for electrons . The electron acceptor of pyruvate/lactate
redox pair (pyruvate) has a greater tendency to gain electrons than the electron
acceptor of the NAD + /NADH redox pair (NAD + ) becaus e the former redox pair has
a greater s tandard reduction potential
than the latter redox pair.
37.(D) Hsp70 protects denatured proteins by binding to regions of unfolded polypeptides
rich in hydrophobic residues , preventing inappropriate aggregation.
38.(B) Steroid hormones (estrogen, proges terone, and cortis ol, for example) are too
hydrophobic to dissolve readily in the blood and are carried on specific carrier
proteins from their point of releas e to their target tiss ues
39.(D) Hydrogen bonds in a polypeptide form between the oxygen atom of the C=O group
of one amino acid and the hydrogen atom of the N-H group of another am ino acid.
40.(B) Proline res idues often occur in β turns becaus e the peptide bond involving the
imino nitrogen of proline ass umes a configuration that is am enable to a tight turn.
41.(C) Sickle-cell hem oglobin m olecules associate abnorm ally with each other, forming
long, fibrous aggregates . These aggregates caus e the dis tortion of the shape of the
erythrocyte
42.(A) There are dis ulphide bonds that link the heavy chains to each other and there is a
disulphide bond that links a light chain to a heavy chain.
43.(D) Each β-oxidation cycle generates one m olecule of NADH, one molecule of FADH 2,
and one molecule of acetyl-CoA, except for the las t β-oxidation cycle, which res ults
in two m olecules of acetyl CoA. Therefore, a 16-carbon s aturated fatty acid will be
completely oxidized by s even β-oxidation cycles , generating eight molecules of
acetyl-CoA.
Phone: 0744-2429714
Mobile: 9001297111, 9829567114, 9001297243
W ebsit e: www.vpmclasses.co m
E-Mail: vpmclasse [email protected] / inf [email protected] m
A ddress: 1-C-8, Shee la Chowdhary Road, SFS, TA LWANDI, KOTA , RAJA STHA N, 324005
Page 32
C SIR NET, GA TE, IIT-JA M, UGC NET , TIFR , IISc , JEST , JNU, BHU , ISM , IBPS , C SAT, SLET, NIMCET, C TET
44.(A) The I band is formed where thick filam ents are abs ent. During s keletal mus cle
contraction, the thick and thin filaments s lide pas t each other, res ulting in the
narrowing of the I band as thick filaments are brought closer together
45.(D) In oxidative phos phorylation, O2 is reduced to H2O at the expense of NADH and
FADH 2, which are oxidized to NAD + and FADH +. In photophos phorylation, H 2O is
oxidized to O2 , with NADP+ accepting electrons from H 2O to generate NADPH.
46.(D) The overall equation of the urea cycle is :
NH3 +CO2 aspartate + 3 ATP + 2 H2O
urea + furm arate + 2 ADP + Pi + AMP +
PPi
47.(A) Clones of plants are made when gardeners grow plants from cuttings, but this fact
has no bearing on the individuality of a hum an clone. The environment and the
genes interact in complex ways to produce the personality, s o a hum an mind
cannot be entirely dependent on environmental factors any more than it can be
entirely dependent on genetic ones . It m ay be true that clones would dis like being
identified with their parent, but they m ay als o relis h the ass ociation – predicting
these feelings is inexact. However, identical twins are indeed hum an beings with
the sam e genomes , and yet they grow up to be very different people. Clones,
raised in even m ore different environments , would probably differ even m ore
greatly. the correct ans wer is 1: Identical twins have very different pers onalities,
and they are essentially clones of each other.
48.(B) Pi release triggers a "power stroke," a conform ational change in the m yos in head
that m oves actin and myosin filaments relative to one another
49.(C) Only immunoblots enable an approxim ation of an antigen's molecular weight
because the ass ay requires the s eparation of proteins in a s ample by an SDS
Phone: 0744-2429714
Mobile: 9001297111, 9829567114, 9001297243
W ebsit e: www.vpmclasses.co m
E-Mail: vpmclasse [email protected] / inf [email protected] m
A ddress: 1-C-8, Shee la Chowdhary Road, SFS, TA LWANDI, KOTA , RAJA STHA N, 324005
Page 33
C SIR NET, GA TE, IIT-JA M, UGC NET , TIFR , IISc , JEST , JNU, BHU , ISM , IBPS , C SAT, SLET, NIMCET, C TET
polyacrylam ide gel, which s eparates proteins by m olecular weight. By comparing
the mobility of the protein antigen of interes t with the mobility of proteins of known
m olecular weight (molecular weight standards ), one can approxim ate the molecular
weight of the antigen. In ELISA assays , proteins in a s am ple are placed inside the
wells of a polys tyrene tray and are never s eparated by size
50.(B) Ka is an ass ociation cons tant that provides a meas ure of the affinity of a ligand L for
a protein P. Ka = [PL]/[P][L]. The reciprocal of the Ka is the dissociation constant Kd.
Kd = [P][L]/[PL]. Therefore, the ans wer with the highes t Ka or the lowes t Kd has the
highes t affinity. The binding cons tant with the highes t affinity is ans wer B: Kd = 1.0
× 10 –9 M, which expressed as a Ka would be Ka = 1.0 × 10 9 M–1
51.(D) The binding of one molecule of O2 to one s ubunit of hem oglobin mediates the
binding of other m olecules of O2 to other s ubunits of hemoglobin by conformational
changes transmitted from one s ubunit to another by s ubunit-s ubunit interactions .
52.(C) Cytoto xic T cells (TC), als o known as killer T cells, des troy virally infected cells . TC
cells identify virally infected cells by having their s urface T-cell receptors bind to
viral antigens displayed on the surface of infected cells .
53.(D) A sigmoid s haped binding curve reflects a transition between a low to a high affinity
s tate. Hemoglobin m us t bind oxygen efficiently in the lungs, where the oxygen
press ure is high, and m us t release oxygen in the tiss ues , where the oxygen
press ure is low.
54.(B) Hem oglobin is an allosteric protein in which the binding of the firs t O2 to a subunit
in the T state leads to conform ation changes of the other subunits to the R s tate,
which has a higher affinity for O 2.
Phone: 0744-2429714
Mobile: 9001297111, 9829567114, 9001297243
W ebsit e: www.vpmclasses.co m
E-Mail: vpmclasse [email protected] / inf [email protected] m
A ddress: 1-C-8, Shee la Chowdhary Road, SFS, TA LWANDI, KOTA , RAJA STHA N, 324005
Page 34
C SIR NET, GA TE, IIT-JA M, UGC NET , TIFR , IISc , JEST , JNU, BHU , ISM , IBPS , C SAT, SLET, NIMCET, C TET
55.(D) A wax is a s imple lipid which is an es ter of a long-chain alcohol and a fatty acid.
The alcohol m ay contain from 12-32 carbon atoms.
56.(D) Hem oglobin does not deliver H + to peripheral tiss ues . Ins tead, it carries the end
products of respiration-H + and CO2-from peripheral tiss ues to the lungs and
kidneys where they are excreted.
57.(D) When the concentration of CO2and H+ is high, the affinity of hem oglobin for oxygen
is decreas ed. This aids in the function of hemoglobin as a trans porter of both
oxygen and cell byproducts . In the peripheral tiss ues where the concentration of
CO2 and H + is high, hem oglobin releases oxygen and takes up CO2 and H +. In the
lungs , as CO2 is excreted and the pH rises , hem oglobin binds m ore oxygen for
transport to the tiss ues
58.(A) The concentrations of the n-3 fatty acids eicosapentaenoic acid (20:5 n-3),
docos apentaenoic acid (22:5 n-3) were higher in the cod liver oil. all-cis7,10,13,16,19-docos apentaenoic acid is an ω - 3 fatty acid with the trivial nam e
clupanodonic acid, comm only called DPA. It is an interm ediary between
eicos apentaenoic acid (EPA, 20:5 ω-3) and docosahexaenoic acid (DHA, 22:6 ω3). Seal oil is a rich source.
59.(B)
60.(B) Allos teric enzymes display sigm oid kinetic behavior rather than hyperbolic kinetic
behavior on s imple plots of Vo vers us [S].
61.(B) Becaus e the s ubs trate and inhibitor compete for the s ame active s ite, a sufficiently
high s ubstrate concentration will always displace the inhibitor from the enzym e's
active s ite.
Phone: 0744-2429714
Mobile: 9001297111, 9829567114, 9001297243
W ebsit e: www.vpmclasses.co m
E-Mail: vpmclasse [email protected] / inf [email protected] m
A ddress: 1-C-8, Shee la Chowdhary Road, SFS, TA LWANDI, KOTA , RAJA STHA N, 324005
Page 35
C SIR NET, GA TE, IIT-JA M, UGC NET , TIFR , IISc , JEST , JNU, BHU , ISM , IBPS , C SAT, SLET, NIMCET, C TET
62.(D) Cellulose is a s tructural polysaccharide in plant cells that give plants tough s talks,
s tems , trunks , and woody parts
63.(A)
Therefore,
64.(D) This is the s afes t vaccine. Such a genetically engineered analog of the cholera
toxin would not be able to bind to or enter cells (and therefore would be harm less)
but m ight s till be able to elicit an immune response. The toxin is a lectin that enters
target cells only after interacting with the carbohydrate moiety on a surface
glycolipid.
65.(C) Penicillin prevents the s ynthes is of the cross -links in the cell wall peptidoglycan of
gram -positive bacteria. This leaves the cell too weak to res is t osm otic lys is .
66.(B) Polys accharides grow in the direction of the nonreducing end
67.(C) The lectin of the influenza virus , the HA protein, binds a sialic acid-containing
oligos accharide on a cell surface glycoprotein, triggering the entry of the virus into
the cell.
68.(D) Nucleos ides lack a phosphate group. Nucleosides (a ribos e sugar and a
nitrogenous base) that contain one or m ore phosphate groups are called
nucleotides .
69.(B)The firs t nucleotide is attached to a s olid s upport. The growing s trand rem ains
attached to this s upport until the oligonucleotide is com plete, at which point the
oligonucleotide is cleaved from the solid s upport and purified.
Phone: 0744-2429714
Mobile: 9001297111, 9829567114, 9001297243
W ebsit e: www.vpmclasses.co m
E-Mail: vpmclasse [email protected] / inf [email protected] m
A ddress: 1-C-8, Shee la Chowdhary Road, SFS, TA LWANDI, KOTA , RAJA STHA N, 324005
Page 36
C SIR NET, GA TE, IIT-JA M, UGC NET , TIFR , IISc , JEST , JNU, BHU , ISM , IBPS , C SAT, SLET, NIMCET, C TET
70.(A) K’ eq = [C][D]/[A][B]. The relations hip between K’ eq and ∆G’° is ∆G’° =–RT ln
K’ eq. The reaction will proceed forward (favor the form ation of products C and (D)
if ∆G’° is negative, which can only be achieved if K’ eq is greater than 1.
71.(C) Under alkaline conditions RNA forms 2’, 3’ cyclic monophos phate derivatives,
resulting in hydrolysis of the phos phodiester bonds that link ribonucleotides in an
RNA chain
72.(A)The number of adenos ine res idues equals the number of thym idine res idues , and the
number of guanos ine res idues equals the num ber of cytidine residues. Therefore, if
A = T and G = C, then A + G = T + C
73.(D) In automated DNA s equencing, the s equencing reactions are electrophores ed
through a capillary tube, and the fluorescent-labeled DNA molecules that pass
through the capillary are read by a laser beam and recorded by a computer
74.(B) The m ajor groove allows cellular proteins to recognize s pecific bas e sequences
75.(B) m RNAs carry the amino acid coding information from DNA so that it can be made
into polypeptide chains by the ribos om e
76.(D) We can rearrange the equation to give :
Therefore, This is the cosine of 30°. You s hould memorize the cosine, sine and
tangents of comm on angles s uch as 0°, 30°, 45°, 60°, 90°, and any
related angles .
Phone: 0744-2429714
Mobile: 9001297111, 9829567114, 9001297243
W ebsit e: www.vpmclasses.co m
E-Mail: vpmclasse [email protected] / inf [email protected] m
A ddress: 1-C-8, Shee la Chowdhary Road, SFS, TA LWANDI, KOTA , RAJA STHA N, 324005
Page 37
C SIR NET, GA TE, IIT-JA M, UGC NET , TIFR , IISc , JEST , JNU, BHU , ISM , IBPS , C SAT, SLET, NIMCET, C TET
77.(A) Nucleos ide diphos phate kinas e catalyzes the trans fer of phosphoryl groups from
ATP to NDPs or dNTPs to generate NTPs or dNTPs , respectively
78.(A)
79.(C) Microphages engulfs foreign material
80.(C) Mitochondria and chloroplas t contains nuclear genetic m aterial
81.(A) An increase in CO2 in C3 mus tard plant from 300ppm to 1000ppm for s ame cycle
keeping other parameters s ame results in increasing photosynthesis and higher
CO2 fi xation in dark cycles .
82.(C) The process of loss of water from leaves is called as trans piration
83.(B) Wooden doors are s wollen during rainy s eason becaus e it im bib es water.
84.(D) Shrinkage of protoplasm occurs due to loss of water called as exosmos is
85.(A) Oxygen availability determines uptake of minerals
86.(D) ABA helps in clos ure of s tom ata.
87.(C) Blue and red light is a key absorption s pectrum .
88.(A) High humidity res ults in lowered trans piration.
89.(C) Root hairs increase area under abs orption
90.(B) Colchicines affects s pindle formation during mitosis by inducing polyploidy.
Phone: 0744-2429714
Mobile: 9001297111, 9829567114, 9001297243
W ebsit e: www.vpmclasses.co m
E-Mail: vpmclasse [email protected] / inf [email protected] m
A ddress: 1-C-8, Shee la Chowdhary Road, SFS, TA LWANDI, KOTA , RAJA STHA N, 324005
Page 38
C SIR NET, GA TE, IIT-JA M, UGC NET , TIFR , IISc , JEST , JNU, BHU , ISM , IBPS , C SAT, SLET, NIMCET, C TET
91.(C) It is in 59 m inutes as a cell divides in one m inute, 60 minutes to fill 100m l beaker.
59 m inutes required to fill half the beaker and remaining one minute for the cells to
fill half are requiring only one minute filling the full beaker.
92.(A) 2 n for n generations
2 n = 128 ; n=7
93.(A) Initiation of polypeptide chain in eukaryotes is similar to the in prokaryotes except:
(A) In eukaryotes form ylation of m ethionine does not takes place.
(B) There are more initiation factor at leas t 10.
(C) 40S subunit ass ocia tes with initiator t-RNA with out the help of m -RNA.
94.(D) Biogas is m ethane and propane rich fuel.
95.(B) Enzym e imm obilization provides protective s hielding for an enzym e
96.(B) Hum uline is a protein
97.(D) Haem olytic dis eas e of the newborn caused by Rh incompatibility is the best
described by delayed hyper sens itivity
98.(D) Allotypes in immunoglobulin are due to polym orphism within a species
99.(A) IgG conc is high in new born baby blood they are s ource of natural antibodies from
m other.
100.(C) CD4 cell are mos t affected in AIDS infection
Phone: 0744-2429714
Mobile: 9001297111, 9829567114, 9001297243
W ebsit e: www.vpmclasses.co m
E-Mail: vpmclasse [email protected] / inf [email protected] m
A ddress: 1-C-8, Shee la Chowdhary Road, SFS, TA LWANDI, KOTA , RAJA STHA N, 324005
Page 39