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10N 29 Poutū-te-Rangi 2017 What we will do What we will learn Quick quiz and preliminaries Revisit genetics intro: dominant, recessive, allele, heterozygous, homozygous, punnett square AND introduce genotype and phenotype How to start well Useful definitions for the buzzwords in this topic See why Cystic Fibrosis happens and what being a “carrier” means Use Punnett squares to compare CF scenarios. How genetic diseases affect humans How being a “carrier” can be passed along If time, do a Punnett square on Jimmy and Jeannie How Punnett squares works with dog breeding 10N – Seating Plan Front of lab - Whiteboard HW item Skills practiced HW booklet pages on skeletal system, muscles and joints, blood and heart, circulatory system Pages 1 - 8 Due Thursday 2nd of March 2017 Time management Knowledge of three systems in the body HW booklet pages 9 – 18: circulatory, breathing and digestive systems. Due Monday 20th of March 2017 Time management Knowledge of three systems in the body HW booklet pages 19, 27, 28, 29 Human Reproduction Due Zenday 37th of Octember Human Reproduction Word Meaning Dominant An allele which controls what an organism looks like. (The more powerful message of the two possible) Recessive Only shows up when there are two of these. (The weaker of the two possible – so it shows up when the other one is missing) Homozygous Containing two identical forms of the same gene. (Both dominant or both recessive) Heterozygous An individual containing two different forms of the gene. Allele Different forms of a gene. Genotype The genetic make-up of an individual. The “type-o’-gene”. i.e. is it heterozygous, homozygous dominant or homozygous recessive? Phenotype The physical characteristics of an individual. “Phenotype” is “the TYPE of PHENOmenon”. i.e. – what shows up. For this breed of dog, long hair (H) is dominant of short hair (h) After mating, Jeanny produces six pups Jimmy (hh – short hair) Jeanny (HH – long hair) 1. Draw up a Punnett square to predict the hair length of the pups. For this breed of dog, long hair (H) is dominant of short hair (h) After mating, Jeanny produces six pups Jimmy (hh – short hair) Jeanny (HH – long hair) 1. Draw up a Punnett square to predict the hair length of the pups. 2. Write down what the phenotype and the genotype are for the pups Cystic Fibrosis This is a genetic disease that is passed on when a baby gets TWO copies of the recessive gene. It is normally fatal, with few living past their 30s. If we use: F = healthy f = cystic fibrosis then: FF = homozygous dominant. Does not have CF & cannot pass it on Ff = heterozygous. Does not have CF but CAN pass it on fF = heterozygous. Does not have CF but CAN pass it on ff = homozygous recessive. DOES have CF and CAN pass it on too. heterozygous people are called “carriers” A Mum is healthy and NOT a carrier. Blood tests have figured this out. She marries a man who has CF and they decide to have kids. What are the chances a baby will have CF? What are the chances a baby will be healthy but a carrier? What are the chances a baby will be healthy but not be a carrier? Use a Punnett square to figure out the answers.