Download BI 215 - Butler Community College

Butler Community College
Science, Technology, Engineering, and
Math Division
Alan R. Brown
New Spring 2016
Implement Fall 2016
Textbook Update Fall 2016
COURSE OUTLINE
Majors Biology I (Cell)
Course Description
BI 215. Majors Biology I (Cell). 5 hours credit. This course will enable the student to
develop an understanding of basic biological chemistry; cell structure and function; cell
metabolism, including cellular respiration and photosynthesis; classical genetics,
including cell reproduction and inheritance processes; molecular genetics, including
nucleic acid and protein processes and regulation; and the evolutionary processes of
cells. The learning outcomes and competencies detailed in this course outline meet or
exceed the learning outcomes and competencies specified by the Kansas Core
Outcomes Groups project for this course as approved by the Kansas Board of Regents.
(Transfers as BIO1020).
Required Materials
Brooker, R. J., Widmaier, E. P., Graham, L. E., & Stiling, P. D. Biology. New York:
McGraw Hill Education.
*For complete material(s) information, refer to https://bookstore.butlercc.edu
Butler-assessed Outcomes
The intention is for the student to be able to:
1. Describe the relationship of cell structures to specific cellular functions.
2. Describe the molecular processes for cellular metabolism.
3. Apply the principles of genetics to patterns of inheritance.
4. Identify the molecular mechanisms for cellular evolution.
Learning PACT Skills that will be developed and documented in this course
Through involvement in this course, the student will develop ability in the following
PACT skill area(s):
Analytical Thinking Skills
 Problem solving - Through analytical thinking, experimental design, calculations,
and the statistical analysis of data, the student will develop skills in experimental
biology.
Technology Skills
 Discipline-specific technology – Through the use of computer software and
biotechnology equipment, the student will develop an understanding of biologic
principles and the ability to execute experimental protocols.
Communication Skills
 Creation and delivery of messages- Through a written report on up-to-date
research on the functioning of a cellular organelle or of a cellular metabolic
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pathway, the student will develop abilities to search, comprehend, and write
about the biology of cells.
Major Summative Assessment Task(s)
These Butler-assessed Outcome(s) and the Learning PACT skill(s) will be
demonstrated by:
1. Designing and executing an experiment that demonstrates a sound scientific
process and reporting the results in a scientific paper format. (A skill)
2. Demonstrating technical expertise in using computer software and biotechnology
laboratory equipment in biology. (T skill)
3. Searching biology literature, organizing content, and writing an up-to-date review
about a cell organelle or metabolic pathway. (C skill)
Skills and Competencies
These actions are essential to achieve the course outcomes:
1. Apply the scientific process to and recognize the variables in experimental design.
2. Recognize basic chemical and biochemical molecules and their bonding properties.
3. Describe the molecular and cellular basis of life and the connection between cell
structure and function.
4. Identify the chemical basis of metabolism, physiological processes, cell respiration
and protein synthesis.
5. Describe the classical and molecular basis of genetics.
6. Demonstrate a comprehension of the molecular processes of evolution.
Learning Units
I.
Scientific process and biologic chemistry
A. Describe the steps in the scientific process and how each relates to a specific
area in a scientific paper
B. Describe the differences between a hypothesis, fact, and interpretation
C. Design an experiment in which you can identify the control, independent and
dependent variables, state the hypothesis in a predictive form, and null and
alternative hypotheses
D. Describe the steps of Koch’s postulates for proving causation in biology
E. Diagram the structural formula from the empirical formula for a given molecule
F. Recognize the structural formulas of the following kinds of molecules: glucose,
fructose, sucrose, maltose, starch, fat or triglyceride (saturated and
unsaturated), amino acid, protein (primary, secondary, and tertiary structure),
peptide bond, and the structures of nucleic acids and nucleotides
G. Describe the difference between an ionic and covalent bond
II.
Cell structures and functions
A. Describe the following cellular parts: cell wall, cell membrane, nucleus,
centriole, ribosome, endoplasmic reticulum (smooth and rough), golgi body,
mitochondria, chloroplast, flagella, and cilia
B. Describe the three major points of the cell theory and the significance of each
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C. Describe the structure of the cell membrane and the roles the double
phospholipid layer and proteins play in its operation
D. Describe the direction of flow across a differentially permeable membrane in
hypotonic, hypertonic, and isotonic solutions
E. Describe the difference between diffusion, osmosis, and active transport
F. Distinguish the differences between prokaryotic and eukaryotic cells
III. Cellular Metabolism
A. Describe the laws of thermodynamics in the context of living cells.
B. Identify the general structure and function of enzymes
C. Describe the effects of pH, solute, and temperature on enzyme activity
D. Describe the characteristics of reduction-oxidation reactions by electrons
E. Describe energy production of cells by glycolysis, Krebs (Citric Acid) cycle, and
electron transport processes
F. Describe the differences in the reactions and products between aerobic and
anaerobic respiration
G. Describe the energy generation and macro molecule synthesis processes of
photosynthesis
IV. Genetics
A. Describe the meaning of the terms: chromosome, chromatid, centromere,
mitosis, mitotic cell division, cytokinesis, zygotes, and gametes
B. Describe the major events that occur during the various phases of mitosis
C. Describe and diagram the major events that occur during meiosis
D. Describe major differences between mitosis and meiosis
E. Describe the difference between homologous and non-homologous
chromosomes
F. Describe the meaning of genotype, phenotype, homozygous, heterozygous,
dominant, recessive, allele, gene, and co-dominant
G. Solve genetic problems for crosses between individuals heterozygous for one
trait and for two traits
H. Identify the kinds of gametes the following genotypes can produce: DdTt, DDTt,
ddTT
I. Describe how Mendel’s work proved that genes behave as particles
J. Describe the principles of dominance, recessiveness, and gene segregation
K. Describe the kinds of inheritance and molecular basis of human genetic
diseases like: cystic fibrosis, galactosemia, phenylketonuria (PKU), sickle cell
anemia, and Huntington’s Chorea
L. Describe the inheritance of blood types – ABO and Rh
M. Describe the inheritance of maleness or femaleness in humans
N. Describe how Down’s syndrome occurs and relate this with non-disjunction
O. Describe the structure of nucleic acids
P. Describe the structural differences between DNA and RNA
Q. Describe how DNA replicates
R. Describe the steps involved in transcription and translation
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S. Describe the roles or meaning of the following: codon, anti-codon, amino acid,
protein, messenger RNA, transfer RNA, ribosome, and nucleolus
V.
Cell molecular processes
A. Describe how DNA functions as genetic material
B. Describe DNA replication and repair processes in eukaryote and prokaryotic
cells
C. Describe transcription processes in cells
D. Describe translation of RNA to protein
E. Describe and contrast the transcriptional regulation of prokaryote and eukaryote
cells
F. Describe the intracellular regulation and recycling of cellular proteins
VI. Molecular genetic technology
A. Describe the processes of DNA isolation
B. Describe the enzymatic cleave of DNA and the analysis/recovery of DNA
fragments
C. Describe the general structure of DNA plasmids and their application to cell
transformation
D. Describe the principles of the polymerase chain reaction
E. Describe the processes of DNA sequencing
F. Describe the comparative sizes of prokaryotic and various eukaryotic organisms
G. Describe the influence of alterations in DNA sequences and transposon
insertions on cell evolution
Learning Activities
Learning activities will be assigned to assist the student to achieve the intended learning
outcome(s) through lecture, instructor and student-led class discussion, student
presentation of current biology news, group laboratory activities, practicing with
laboratory equipment, unit questions to answer, and other activities at the discretion of
the instructor. These activities may either be face-to-face or online.
Grade Determination
The student will be graded on learning activities and assessment tasks. Grade
determinants may include the following: daily work, quizzes, unit tests, laboratory
research projects, presentations, class participation, and other methods of evaluation at
the discretion of the instructor.
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