Download Calcitonin

CALCITONIN
By Mollie Rubinstein
GLAND
 The Gland that secretes the
hormone is the Thyroid Gland.
 Particularly from the
Parafollicular or from C Cells in the
Thyroid Gland.
 The Thyroid gland is located
anterior to the trachea. Right below
the voice box.
CHEMICAL
C L A S S / TA R G E T T I S S U E
 Calcitonin is in the Amino Acid Class.
 Target Tissues/Organs: Bone, Kidneys and Intestines. There are 3
effects:
• Bone: Calcitonin prevents the activity of Osteoclasts. (Keeps
calcium in bones).
• Kidney: Calcitonin prevents calcium tubular reabsorption.
• Intestine: Prevents calcium absorption in the Intestines.
S O U RC E O F C O N T RO L A N D
H O M E O S TA S I S
 Increased blood calcium levels stimulate the secretion of Calcitonin.
 This secretion is prevented when the concentration of calcium in the blood falls below normal.
 Oesterogens regulate the secretion of Calcitonin. Menopause increases the reduction of
secreting Calcitonin in women.
 The right amount of calcium is needed in the blood to prevent malfunctions such as cardiac
arrhythmia.
 Calcitonin prevents the blood from having too much calcium by allowing the kidneys to cause it
to excrete in Urine and preventing the intestines from absorbing it. This allows for the body to
maintain normal calcium levels and therefore, Homeostasis.
HYPER AND HYPO
Hypersecretion (Too much Calcium in Blood)
1.) Irregular Heart Beat
2.)Abnormal Bone Growth and Structure
3.) Is not the cause of, but can be a symptom of Thyroid cancer.
4.) Can cause calcium to build up in blood and cause Heart Disease.
Hyposecretion (Not Enough Calcium in Blood)
1.) Osteoporosis  Injuries
2.) Muscle Cramping
ANALOGY
 Calcitonin is to the body as a flower stake is to a tall plant.
 Without it, the
plant’s structure
would not hold,
and it would break
Without it, 
our structure
would not hold
and we would
break.
BIBLIOGRAPHY
 http://arbl.cvmbs.colostate.edu/hbooks/pathphys/endocrine/thyroid
/calcitonin.html
 http://www.redorbit.com/education/reference_library/health_1/hum
an-anatomy/1112796052/thyroid-and-parathyroid-glands/\
 http://www.news-medical.net/health/Calcitonin-What-isCalcitonin.aspx
 http://www.ncbi.nlm.nih.gov/pubmed/6896553
 http://www.yourhormones.info/hormones/calcitonin.aspx