Download Hormone-relationships

Releasing Hormones: Hormones produced by the hypothalamus which control the production and release of
the hormones by the anterior pituitary.
Releasing Hormones:
1. corticotropin releasing hormone (CRH): stimulates production and release of ACTH
2. thyroid releasing hormone (TRH): stimulates the production and release of TSH
3. somatostatin (Growth Hormone inhibiting Factor): inhibits the production and release of growth hormone
4. growth hormone releasing hormone: stimulates the production and release of growth hormone
5. gonadotropin releasing hormone (GnRH): stimulates the production and release of FSH and LH
(Note: Given the GnRH stimulates the production and release of both FSH and LH, you would expect
the pattern of release for both hormones to be identical. It is not. The pattern of production and
release of FSH and LH differ because inhibin (from the ovarian follicle and the corpus luteum) acts
directly at the anterior pituitary to inhibit the production and release of FSH.
6. dopamine: inhibits the production and release of prolactin
Hormone relationships you should know:
------> = stimulates production and release
---/---> = inhibits production and release
GnRH------>LH
GnRH------>FSH
inhibin---/--->FSH (directly at the anterior pituitary, not through GnRH)
LH------>estrogen (ovarian follicle and corpus luteum)
moderate estrogen------>GnRH
high or low estrogen---/--->GnRH
dopamine---/--->prolactin
progesterone---/--->GnRH
TRH------>TSH
TSH------>T4,T3
T4, T3---/--->TRH and TSH
Low osmolarity ------>ADH
GHRH------>GH
IGF-1---/--->GHRH via somatostatin
There are more relationships you should know, add on to this list using the textbooks provided in class.