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Transcript
Are There Genetic Paths Common to Obesity,
Cardiovascular Disease Outcomes, and Cardiovascular
Risk Factors?
by Tuomo Rankinen, Mark A. Sarzynski, Sujoy Ghosh, and Claude Bouchard
Circulation Research
Volume 116(5):909-922
February 27, 2015
Copyright © American Heart Association, Inc. All rights reserved.
Pleiotropy of genes with primary association to (A) coronary artery disease (CAD) and (B) body
mass index (BMI).
Tuomo Rankinen et al. Circ Res. 2015;116:909-922
Copyright © American Heart Association, Inc. All rights reserved.
Enrichment of biological pathways and toxicity gene signatures among pleiotropic genes.
Tuomo Rankinen et al. Circ Res. 2015;116:909-922
Copyright © American Heart Association, Inc. All rights reserved.
Interaction networks underlying pleiotropic genes.
Tuomo Rankinen et al. Circ Res. 2015;116:909-922
Copyright © American Heart Association, Inc. All rights reserved.
Analysis of potential regulatory functions of single nucleotide polymorphisms (SNPs) located in
pleiotropic regions.
Tuomo Rankinen et al. Circ Res. 2015;116:909-922
Copyright © American Heart Association, Inc. All rights reserved.