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Transcript
Marieb Chapter 13 Part A PNS
Student version
Copyright © 2010 Pearson Education, Inc.
Peripheral Nervous System (PNS)
• All neural structures outside the brain
•
•
•
Copyright © 2010 Pearson Education, Inc.
Central nervous system (CNS)
Peripheral nervous system (PNS)
Sensory (afferent)
division
Copyright © 2010 Pearson Education, Inc.
Motor (efferent) division
Somatic nervous
system
Autonomic nervous
system (ANS)
Sympathetic
division
Parasympathetic
division
Figure 13.1
Sensory Receptors
• Specialized to respond to changes in their
environment (stimuli)
• Activation results in
•
(awareness of stimulus) and
(interpretation of the meaning
of the stimulus) occur in the brain
Copyright © 2010 Pearson Education, Inc.
Classification of Sensory Receptors
• Can do this based on:
• Stimulus type
• Location
• Structural complexity
Copyright © 2010 Pearson Education, Inc.
Classification by Structural Complexity
1. Complex receptors (special senses)
•
Vision, hearing, equilibrium, smell, and taste
2. Simple receptors for general senses:
•
Tactile sensations (touch, pressure, stretch,
vibration), temperature, pain, and muscle sensation
•
Unencapsulated (naked) or encapsulated dendrites
(covered) as sensors
Copyright © 2010 Pearson Education, Inc.
Unencapsulated Dendrites
• Thermoreceptors
• Cold receptors (10–40ºC)
• Heat receptors (32–48ºC)
•
Also located in
Copyright © 2010 Pearson Education, Inc.
Unencapsulated Dendritic Endings
• Nociceptors (PAIN
receptors!)
• Respond to:
•
•
•
•
• Located in skin, periosteum, joint capsules, tendons,
meninges, blood vessel walls, etc.
Copyright © 2010 Pearson Education, Inc.
Unencapsulated Dendrites
• Light touch receptors
• Tactile (Merkel) discs
• Hair follicle receptors
Copyright © 2010 Pearson Education, Inc.
Copyright © 2010 Pearson Education, Inc.
Table 13.1
Encapsulated Dendrites
• All are mechanoreceptors
•
We will discuss:
• Muscle spindles—muscle stretch
• Golgi tendon organs—stretch in tendons
• Joint receptors—stretch in
articular capsules (a proprioceptor)
Copyright © 2010 Pearson Education, Inc.
Copyright © 2010 Pearson Education, Inc.
Table 13.1
Classification by Stimulus Type
• Mechanoreceptors—respond to touch, pressure,
vibration, stretch, and itch
• Thermoreceptors—sensitive to changes in temperature
• Photoreceptors—respond to light energy (e.g., retina)
• Chemoreceptors—respond to chemicals (e.g., smell,
taste, changes in blood chemistry)
• Nociceptors—sensitive to pain-causing stimuli (e.g.
extreme heat or cold, excessive
pressure, inflammatory chemicals)
Copyright © 2010 Pearson Education, Inc.
Classification by Location
1. Exteroceptors
•
Respond to stimuli arising outside the body
•
Receptors in the skin for touch, pressure,
pain, and temperature
•
Most special sense organs in this class
Copyright © 2010 Pearson Education, Inc.
Classification by Location
2. Interoceptors (visceroceptors)
•
Respond to stimuli arising in internal viscera
and blood vessels
•
Sensitive to chemical changes, tissue
stretch, and temperature changes
Copyright © 2010 Pearson Education, Inc.
Classification by Location
3. Proprioceptors
•
Respond to stretch in skeletal muscles,
tendons, joints, ligaments, and connective
tissue coverings of bones and muscles
•
Inform the cerebellum and cortex of our
position in space
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From Sensation to Perception
• Survival depends upon sensation and
perception
• Sensation: the awareness of changes in the
internal and external environment
• Perception: the conscious interpretation of
those stimuli
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Sensory Integration
• Input comes from exteroceptors,
proprioceptors, and interoceptors
• Input is relayed toward the head, but is
processed along the way
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Sensory Integration
•
The signal can be processed and altered at
three different levels:
1. Receptor level—the sensor receptors
2. Circuit level—ascending pathways
3. Perceptual level—neuronal circuits in the
cerebral cortex
Copyright © 2010 Pearson Education, Inc.
Perceptual level (processing in
cortical sensory centers)
3
Motor
cortex
Somatosensory
cortex
Thalamus
Reticular
formation
Pons
2 Circuit level
(processing in
Spinal
ascending pathways) cord
Cerebellum
Medulla
Free nerve
endings (pain,
cold, warmth)
Muscle
spindle
Receptor level
(sensory reception Joint
and transmission
kinesthetic
to CNS)
receptor
1
Copyright © 2010 Pearson Education, Inc.
Figure 13.2
Processing at the Receptor Level
• Stimulus energy is converted into a graded potential
called a receptor potential (don’t pay attention to the
term generator potential- only used with special
senses)
• In general sense receptors, it works like this:
stimulus


Copyright © 2010 Pearson Education, Inc.
Processing at the Receptor Level
• In special sense organs:
stimulus




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Adaptation of Sensory Receptors
• Adaptation is a change in sensitivity in the
presence of a constant stimulus
• Receptor membranes become less responsive
• So the receptor potentials decline in frequency
or stop
• Why does this happen? Is it a good thing?
Copyright © 2010 Pearson Education, Inc.
Adaptation of Sensory Receptors
• Phasic (fast-adapting) receptors adapt
• Examples:
• Tonic receptors adapt very slowly or not at all
• Examples:
Copyright © 2010 Pearson Education, Inc.
Adaptation - What Happens to Signaling?
Copyright © 2010 Pearson Education, Inc.
Processing at the Circuit Level
• Ascending pathways of three neurons conduct
sensory impulses to the appropriate brain regions
• First-order neurons
• Conduct impulses from the receptor level to the
second-order neurons in the CNS
• Second-order neurons
• Transmit impulses to the thalamus or cerebellum
• Third-order neurons
• Conduct impulses from the thalamus to the
somatosensory cortex (perceptual level)
Copyright © 2010 Pearson Education, Inc.
Perception of Pain
• Definition: an unpleasant sensory and emotional
experience associated with actual or potential tissue
damage
• Warns that you are “at the edge of a cliff!”
• Stimuli include:
•
•
•
Some pain impulses are blocked by inhibitory
endogenous opioids (
)
• Is pain necessary?
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Referred Pain
• Visceral pain afferent fibers travel along the
same pathway as somatic pain fibers
• Referred Pain = pain stimuli arising in the
viscera are perceived as somatic in origin
• Examples:
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Referred Pain
Heart
Lungs and
diaphragm
Liver
Gallbladder
Appendix
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Heart
Liver
Stomach
Pancreas
Small intestine
Ovaries
Colon
Kidneys
Urinary
bladder
Ureters
Pain
• Does everyone have the same pain threshold?
• Does everyone have the same pain tolerance?
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Pain
• Pain tolerance is influenced by many factors:
•
•
•
•
•
•
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How Is Pain Processed?
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Analgesia
• Defined as “
“
• Major Analgesics
•
•
• Other agents that can act as pain relievers
•
•
•
•
•
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•
Classification of Nerves
• Peripheral nerves classified as cranial or spinal nerves
• Most nerves are mixtures of afferent and efferent
fibers and somatic and autonomic (visceral) fibers
(carry sensory + motor = mixed nerves)
• Pure sensory (afferent) or motor (efferent) nerves are
rare (which cranial nerves are purely sensory?)
• Types of fibers in mixed nerves:
• Somatic afferent and somatic efferent
• Visceral afferent and visceral efferent
Copyright © 2010 Pearson Education, Inc.
Regeneration of Nerve Fibers
• Mature neurons can’t divide
• If the soma of a damaged nerve is intact, its axon will
regenerate
• Involves coordinated activity among:
• Macrophages
• Schwann cells
• Axons
• CNS oligodendrocytes bear growth-inhibiting proteins
that prevent CNS fiber regeneration (UGH!)
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