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Endocrine System, Maintaining Homeostasis Chemical Control vs Electrochemical Control • Cells communicate electrochemically (nerve impulse) very rapidly. Cells also communicate chemically (hormones). Chemical communication is slower but the results last longer. • Hormones are chemical regulators produced by cells in one part of the body that affect cells in another part of the body. • In most animals, chemical communication takes place through the glands. Glands are specialized to secrete substances needed by the body. The two major types of glands are: 1. Exocrine Glands – release chemicals into ducts that empty into an organ where the chemical produces its effect. Examples of Exocrine Glands a) Salivary glands – release saliva into the mouth b) Sweat glands – release sweat to the skin’s surface c) Digestive glands – release enzymes that digest food 2. Endocrine Glands – release chemicals directly into the bloodstream to carry chemicals to areas where they are needed. Lacking ducts, they are sometimes called ductless glands. Endocrine glands produce chemicals called hormones. Examples of Endocrine Glands a) Adrenal gland – produces adrenaline b) thyroid – produces thyroxine Types of Hormones Hormones are divided into two main classes based on their chemical structure. 1. Protein hormones – are composed of long chains of amino acids’ 2. Steroid hormones – are made from cholesterol How Hormones Work • Glands are made up of regulator cells. • These cells detect change in the environment (internal or external). • When these cells detect a change, they respond by producing a hormone. • The hormone circulates throughout the blood stream and is delivered to the cells that respond to change. • The cells affected by hormones are called target cells. One-messenger model • The one-messenger model of hormone action means hormones enter the cell membrane directly to exert their effect. • Steroid hormones work this way. Two-messenger model • Some hormones cannot pass directly through the cell membrane. First, they attach to a special protein on the cell’s surface called a receptor. • The interaction between the hormone and the receptor activates an enzyme which causes the production of a second messenger that produces the desired effect. • This is called the two-messenger model of hormone action. Protein hormones work this way. • Assigned Readings: P. 372, 373, 374