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ENZYMES Enzymes • Are Proteins • Chemical CATALYSTS which speed up the rate of chemical reactions by lowering the activation energy - the energy needed to get a reaction started • Chemical Reactions = a process that changes or transforms one set of chemicals into another Chemical Reactions • Reactants = Substrates • Reactants (substrates) are elements or chemicals which ENTER into the reaction (on the DULL side of the arrow) • CO2 + H2O--->H2CO3 (carbonic acid) • Products - elements or compounds produced (made or formed) by the reaction (on the pointed side of the arrow) • CO2 + H2O ---> H2CO3 (carbonic acid) Energy • Reactants must collide with enough energy to break old bonds and form new ones • Some reactions RELEASE energy ie: 2H2+O2---> 2H2O + heat • Some reactions ABSORB energy ie: 2H2O----> 2H2+O2 (energy is needed - light reactions of photosynthesis) • Energy is stored in the bonds between molecules • Matter and energy must be conserved - some reactions happen slowly, others happen quickly Enzymes • Provide a SITE (place) where reactants (substrates) can be brought together to react – • the SITE reduces the energy needed • ACTIVE SITE - is a specific shape so that only those substrates will fit = lock & key Factors affecting enzyme reaction rates • pH - some work better in low pH ie: pepsin in stomach • Temperature - most enzymes work at normal body temperature (37 degrees Celsius or 98 degrees F) • Regulatory molecules - switch enzymes on or off Factors affecting enzyme reaction rates • Enzyme concentration - the amount of enzymes available • Substrate concentration - the amount of substrates needed to be worked on • Denaturing - changes in the shape of the protein (enzyme) or the active site ie - frying an egg