Download Unit 7 Molecular Genetics Module 1 DNA Discovery

UNIT 8 MOLECULAR GENETICS
CHAPTER 16 MODULE #1
THE DISCOVERY OF DNA AND IT’S STRUCTURE
1. Below is a diagram representing Frederick Griffin’s 1928 experiment attempting to show that
DNA was the heritable genetic material. Give a brief description of his methods AND findings.
2. Below is a diagram of Oswald Avery’s 1944 experiment to show that DNA was the heritable
genetic material. Give a brief description of their methods AND findings.
3. Below is a diagram representing Alfred Hershey and Martha Chase’s 1952 experiment to show
that DNA was the heritable genetic material. Give a brief description of their methods AND
findings.
4. Below is a graph representing Erwin Chargaff’s contribution to the discovery of the structure of
DNA. Give a brief description of his contribution and include what is meant by” Chargraff’s
rules”.
5.
Who is the following scientist and what was her contribution to the discovery of DNA’s
structure?
6. Who are the following scientist and what was their contribution to the discovery of DNA’s
structure? When did they make this discovery? What “prize” were they awarded?
7.
8.
Below is a diagram representing the structure of a DNA strand. Label the following
structures: Sugar-phosphate backbone, nitrogen bases, phosphate, deoxyribose, nucleotide,
thymine, adenine, cytosine, and guanine.
Below is a diagram representing the “double helix” structure of DNA.
How wide is a DNA strand?
What is the distance between two pairs of nitrogen bases (rungs of the ladder)?
How many nitrogen base pairs are there in one complete twist of the DNA strand?
9. Which two nitrogen bases are the pyrimidines? Which two are the purines? What is the
structural difference between pyrimidines and purines? What type of bonds form between
nitrogen bases? In the diagram below, label the nitrogen bases.