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Genetic Engineering Webquest Topics In Biology Professor Rizzo A. History of Mapping http://www.accessexcellence.org/RC/AB/IE/Short_History_of_Mapping.html 1. How could a gene map lead researchers to new frontiers in drug development? 2. What is recombinant DNA? http://www.accessexcellence.org/RC/AB/BA/aapost/firstcommerce.html 3. What was the first commercial use of genetic engineering? http://www.accessexcellence.org/RC/AB/BA/aapost/otheruses.html 4. Identify some other commercial uses gebetic engineering http://www.accessexcellence.org/RC/AB/IE/Speaking_Language_rDNA.html 5. Letters: ___________ (DNA, Codons, Genes , Nucleotide Bases ) Words: ___________ Sentences: ________ Book: ____________ http://www.accessexcellence.org/RC/AB/IE/Biotechnologys_Impact.html 6. Please summarize the major points of the site above. a) A High-Tech, Low-Risk Technology b) Is Biotechnology Safe? c) Legal Implications B. Human Genome Project http://www.accessexcellence.org/RC/AB/IE/Intro_The_Human_Genome.html 7. What was the goal of the Human Genome Project? 8. What is a genome? 9. What is the “Map of the genome”? http://www.accessexcellence.org/RC/AB/IE/Whose_Genome_is_It.html 10. Who owns researched DNA? 11. How are cells "immortalized"? http://www.accessexcellence.org/RC/AB/BC/J_Michael_Bishop.html 12. Discuss some ethical concerns behind the Human Genome Project. http://www.accessexcellence.org/RC/AB/BC/J_Michael_Bishop.html 13. What is an oncogene? C. Altering DNA http://www.accessexcellence.org/RC/AB/BA/Gene_Therapy_Overview.html 14. Discuss what is meant by the phrase “altered genes”. 15. What are “genetic metabolic diseases”? http://www.accessexcellence.org/RC/AB/BA/aapost/genetherapy.html 16. What is Gene Therapy? 17. How can it be used to assist children with cystic fibrosis? http://www.accessexcellence.org/RC/AB/BA/The_Biopharmaceuticals.html 18. Look over the list of FDA Approved biopharmaceuticals and write down two that may have an impact on you or your family. _____________________________: Treatment for ________________________________________ _____________________________: Treatment for ________________________________________ D. Genetically Modified (GM) / Biotechnological Products and Their Uses Identity http://www.accessexcellence.org/RC/AB/BA/Interview_Weir.html 19. What is DNA fingerprinting? 20. Could there be a concern about using these technologies? Bacteria Uses http://www.accessexcellence.org/RC/AB/BA/aapost/feedstocks.html 21. Identify the benefits of Bioplastics. http://www.accessexcellence.org/RC/AB/BA/Biomining.html 22. Explain what is Biomining? http://www.accessexcellence.org/RC/AB/BA/Cleaning_Up_Wastes.html 23. What is Bioremediation? Agriculture http://www.biotech-info.net/AAASgen.html http://www.accessexcellence.org/RC/AB/BA/Agriculture_Overview.html 24. In three reasons why foods are being genetically modified? 25. Identify four concerns that are making people nervous about genetically modifying agricultural products. http://www.accessexcellence.org/RC/AB/IE/Challenges_Policy.html 26. After reading this like above discuss the following: 27. What are the challenges that new science throws at old policies? 28. What allows the FDA regulate genetically engineered food? http://www.accessexcellence.org/RC/AB/BA/Gene_Gun_Orchid_Color.html 29. How does a Gene Gun work? Transgenic Farm Animals http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/T/TransgenicAnimals.html 30. Explain what is a transgenic animal? 31. How did researchers use transgenic mice? http://www.accessexcellence.org/RC/AB/BA/casestudy4.html 32. How many sheep were needed to produce Dolly? http://news.nationalgeographic.com/news/2002/01/0111_020111genmice.html 33. How did research get these mice to fluoresce under UV light? http://www.accessexcellence.org/RC/AB/BA/asilomar.html 34. Identify two major concerns using GM products to feed the world 35. Briefly, Research and explain how the GM Technologies below are being uses and applied…BRIEFLY Biochips Bioterrorism Xenotransplantations Designer Babies Eugenics (be careful of the sites you visit) Other links: http://www.accessexcellence.org/RC/AB/BA/aapost/apmaster.html The five “Fs: Food, Fiber, Fuel, Feedstocks, Pharmaceuticals http://www.accessexcellence.org/RC/AB/BA/aapost/toolsmaster.html What are the tools of biotechnology? http://www.accessexcellence.org/RC/AB/BA/aapost/backmaster.html How old is biotechnology? What is genetic engineering?