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Name ____________________________________ Date ____________ Period _____ Agents of Evolutionary Change Raven Ch. 21 Big Idea 1: THE PROCESS OF EVOLUTION DRIVES THE DIVERSITY AND UNITY OF LIFE. It is not the strongest of the species that survives, nor the most intelligent that survives. It is the one that is the most adaptable to change. ― Charles Darwin (1859) Essential Knowledge:            Natural selection is a major mechanism of evolution Natural selection acts on phenotypic variations within populations. Evolutionary change is also driven by random processes. Biological evolution is supported by scientific evidence from many disciplines including mathematics Organisms share many conserved core processes and features that evolved and are widely distributed among organisms today. Phylogenetic trees and cladograms are graphical representations (models) of evolutionary history that can be tested Speciation and extinction have occurred throughout the Earth’s history. Speciation may occur when two populations become reproductively isolated from each other. Populations of organisms continue to evolve. There are several hypotheses about the origin of life on Earth, each with supporting scientific evidence. Scientific evidence from many different disciplines supports models of the origin of life. Populations Evolve! o Natural Selection__________________________________________________________  ______________________ results in: o differential survival  o differential reproductive success  o “survival of the fittest” who bears more offspring _______________________ evolve  __________________ makeup of population changes over time  favorable traits (_____________________________) become more common Individuals ___________________ evolve… Individuals __________________ or ______________________… Individuals __________________________ or ________________… Individuals ______________________ evolve… Individuals are ______________________ ___________________________ evolve 1 o Variation & Natural Selection   ________________________ is the raw material for natural selection o there have to be _____________________ within population o some individuals must be __________________ than others ________________________- Survival & Reproductive success o o individuals with one phenotype leave more surviving offspring Where does Variation come from?  _______________________   _________________ changes to _________________  errors in mitosis & meiosis (cell division)  environmental damage _________________  mixing of alleles  ______________________ of alleles o   new combinations = new phenotypes spreads variation  Examples: new arrangements in every offspring offspring inherit traits from parent _____________________________________________________, _____________________________________________________, _____________________________________________________, _____________________________________________________, How can the alleles within a population change (evolution)? 5 Agents of evolutionary change 1. ___________________________________ 2. ___________________________________ 3. ___________________________________ 4. ___________________________________ 5. ___________________________________ 2 1. Mutation & Variation  Mutation creates __________________________________ o Mutation rates in _________________________ are __________________ (1 in 100,000 division) o  But are constantly appearing in _________________________ Mutation changes __________________________________________. o As a result, may change:   Protein amino acid sequence  may change protein _________________________?  may change protein _________________________? changes in protein may change __________________ & therefore change __________ 2. Gene Flow  Movement of ___________________ & ____________________ in & out of populations  seed & pollen distribution by __________________________  __________________ of animals 1. sub-populations may have different allele frequencies 2. causes _____________________________ across regions 3. ________________________ differences between populations 3. Non-random mating  ______________________________ 4. Genetic drift  Effect of __________________ events o founder effect  o small group splinters off & starts a new colony bottleneck  some factor (disaster) reduces population to small number & then population recovers & expands again 3 5. Natural selection  Differential ___________________ & _________________ due to changing environmental conditions   climate change  food source availability  predators, parasites, diseases  toxins combinations of _______________________ that provide “_________________” ______________ in the population  _________________________ evolutionary change 4 Measuring Evolution in Populations through Hardy-Weinberg Raven Ch. 21 Populations & gene pools  Concepts:  a ____________________________ is a localized group of ___________________ individuals  gene pool is collection of ______________________ in the population   remember difference between alleles & genes! ________________________________ is how common is that allele in the population  how many _____ vs. _____ in whole population Evolution of populations  Evolution = ________________________________________________________________________  Hypothetical: what conditions would cause allele frequencies to NOT change?  ________________________________________________  _____________________________ all agents of evolutionary change 1. very large population size (no _______________________________) 2. no migration (no __________________________ in or out) 3. no _____________________________ (no genetic change) 4. _______________________________ (no sexual selection) 5. no ___________________________________ (everyone is equally fit) Hardy-Weinberg equilibrium  _____________________________________________________________   preserves allele frequencies Serves as a model (________________________ hypothesis)  natural populations ________________________ in H-W equilibrium  useful model to ___________________________ if forces are acting on a population  measuring evolutionary change Hardy-Weinberg theorem  Counting _____________________________________  assume ____________ alleles = _______, _______  frequency of dominant allele (B) = ________  frequency of recessive allele (b) = ________  frequencies must add to 1 (100%), so: _____ + _____ = 1 5  Counting ____________________________________ ( _____________________________)  frequency of ______________________: p x p = _____  frequency of ______________________: q x q = _____  frequency of ______________________: (p x q) + (q x p) = ______  frequencies of all individuals must add to 1 (100%), so: __________________________ H-W formulas: Alleles: H-W Problem: Individuals: Population: 100 cats, 84 black, 16 white How many of each genotype? Must assume population is in H-W equilibrium Sample Data: How do you explain the data? Sample Data: How do you explain the data? 6 Application of H-W principle  _______________________________  inherit a mutation in gene coding for _________________________  oxygen-carrying blood protein  recessive allele = ___________     normal allele = ___________ low oxygen levels causes RBC to sickle  breakdown of RBC  clogging small blood vessels  damage to organs often __________________ Sickle cell frequency  High frequency of ___________________________  1 in 5 in Central Africans = HbHs  unusual for allele with severe detrimental effects in homozygotes  1 in 100 = HsHs  usually die before reproductive age Why is the Hs allele maintained at such high levels in African populations? Answer: ________________________________  In tropical Africa, where malaria is common:  ________________________________ (normal)   die or reduced reproduction from malaria: HbHb ________________________________   die or reduced reproduction from sickle cell anemia: HsHs ________________________________ are relatively free of both: HbHs  survive & reproduce more, more common in population Example: 7