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Science 4th primary 2nd term unite1 lesson 2 6 – avoid dangers Lesson 1: The importanc e of levers The main principles of hereditary Introduction: What’s the reason for similarities of traits between family members? Genes are transferred from a generation to the next & the genes affect the traits of organisms. Key term; A trait is a distinct physical characteristic of an organism which is inherited ( got from the parents) or acquired ( determined by the environment ). Example; Eye color The color of the skin The number of fingers Blood groups The gene is heritable unit which is a portion of the chromosome.The gene influences the trait. The chromosome is a compact string of DNA. Mendel’s experiment: Gregor Mendel is the founder of heredity he conducted experiments on pea plants because : 1 Ms. Marim Science 4th primary 2nd term unite1 lesson 2 a- Pea plants are grown fast & easily. b- Their life cycle is short. c- Their flowers are hermaphrodite ( either male or female). Flowers can be self pollinated or artificially pollinated by man. d- They produced a large crop. e- Peas have different types with different traits, so comparison between them is clear. For example a type has long stem & another has short stem. A type with white flowers & another with purple ones. The pods of one pea plant are green while another type has yellow pods. Mendel’s experiment with pea plants to study the seed colors. 1- Pea plants that produced yellow seeds were self pollinated for few generations to ensure a pure trait. The same was done to the type with green seeds. 2- The seeds that resulted were then planted. When their flowers appeared, Mendel removed the stamens before the anther matured. 3- Mendel used cross pollination between a plant which produces green seeds & another which produces yellow seeds, then he covered the pistils to prevent further pollination. The results of Mendel’s experiments were as follow: green Yellow parents First generation yellow seed peas 2 Ms. Marim Second generation Science 4th primary 2nd term unite1 lesson 2 Observation: st All the seeds of the 1 generation were yellow. Green color disappeared. Therefore yellow is the dominant trait while green is the recessive trait. When the first generation plants were allowed to self pollinate, they produced the second generation where ¼ had green seeds & ¾ had yellow seeds. -The dominant character appears in all the individuals of the first generation . -The recessive trait disappears in the individuals of the first generation & appears in the second generation. The same procedure was used to study other traits such as long stems versus short stem ....etc. Mendel chose 7 characters & concluded the dominant & recessive trait. 3 Ms. Marim Science 4th primary 2nd term unite1 lesson 2 Mendel concluded the following from the observations he got: Traits are transmitted from parents to offspring by means of hereditary factors now known as genes. Each trait has 2 factors (genes) one gene is inherited from the father & the other is inherited from the mother. If both genes are similar, the trait that appears is pure. When the 2 genes responsible for a certain trait are different this results in an impure trait (the person that has the trait is a hybrid). During meiosis, gametes are formed. Each gamete has only one gene for a certain trait. Mendel’s laws of inheritance: 1. The law of segregation: Mating 2 individuals with contrasting traits results in the appearance of the dominant trait alone in the first generation. In the second generation both traits appear & the ratio between the dominant trait & the recessive one is 3:1 Segregation of Alleles During gamete formation, alleles segregate from each other so that each gamete carries only a single copy of each gene. Each F1 plant produces two types of gametes—those with the allele for tallness and those with the allele for shortness. The alleles are paired up again when gametes fuse during fertilization. The TT and Tt allele combinations produce tall pea plants; tt is the only allele combination that produces a short pea plant. Using symbols to represent the results of Mendel’s experiments: C : symbol of the dominant yellow color, small c symbol of the recessive green color. CC : a pure dominant trait. cc : represents a pure recessive trait. cc C 1st filial generation ( F1) X c C Parents c (P) (G) Cc yellow hybrid seeds 4 Ms. Marim CC Gametes Science 4th primary 2nd term unite1 lesson 2 Now 2 individuals from the 1st generation pollinate as follows: Parents (P) C c c C C Gametes c x C c (G) 2nd filial generation (F2) CC Cc cc Cc Pollinating 2 pea plants with different flower colors. Yellow seeds Green seeds ( contrasting trait). Purple flowers are dominant while white flowers are recessive. PP purple Parents P x pp white Gametes P p p Pp 1st filial generation (F1) Two hybrid plants from the 1st generation mate as follows Parents P p PP Pp P Pp Purple flowers hybrid purple X Pp hybrid purple Gametes p pp 5 Pp White flowers Ms. Marim Science 4th primary 2nd term unite1 lesson 2 Mendel’s 2nd law: The law of independent assortment of hereditary factors Mendel conducted a mixed pollination between : parents Long stem & purple flowers 2 dominant traits First generation Second generation Short stem & white flowers 2 recessive traits with All plants had purple flowers & long stems 9 long stem & 3 long stem & 3 short stem purple white flowers & purple flowers flowers 1 short stem & short flowers Conclusion : 1- The ratio between the dominant trait & the recessive trait is 12:4 = 3:1. 2- Each trait is inherited independently of the other. During gamete formation , the segregation of the alleles of one allelic pair is independent of the segregation of the alleles of another allelic pair, therefore when 2 individuals with 2 contrasting traits mate , the traits of each pair is inherited independently & appears in the 2nd generation in a ratio 3:1 Enriching information : The inheritance of some traits don’t follow Mendel’s laws, these are non. Mendelian hereditary . 6 Ms. Marim Science 4th primary 2nd term unite1 lesson 2 An activity: Mixed pollination between: Smooth yellow seeds pea plants + wrinkled , green seeds pea plants Dominant traits Recessive traits Observations: 1. In the first generation, pea plants had the dominant traits only ( smooth & yellow seeds). 2. First generation produce the following gametes . YR , Yr , yR , yr 3. The second generation plants produce smooth shaped yellow seeds : wrinkled 9 yellow seeds : smooth & green seeds : wrinkled & green seeds. 3 : 4. : 3 1 The ratio of green seeds to the yellow in the second generation is 12:4 3:1 5. 6. The ratio of smooth seeds to wrinkled ones in the second generation is also 12:4 3:1 7 Ms. Marim Science 4th primary 2nd term unite1 lesson 2 Some dominant & recessive traits which appear in humans & follow Mendelian hereditary laws : Dominant trait Recessive trait 1- The ability to roll the tongue Can’t roll tongue 2- Separate ear lopes Connected ear lopes 3- Wide eyes Narrow eyes 4- Curly hair Straight hair 5- Presence of dimples Absence of dimples 8 Ms. Marim Science 4th primary 2nd term unite1 lesson 2 6- A face without freckles A face with freckles 7- Brown eyes Colored eyes Mutations During DNA duplication, mistakes in DNA replication can occur, the base sequence of the newly formed DNA differs from base sequence of the original DNA. The change in the nucleotide sequence of DNA molecule is called mutation. Mutations disrupt the gene & therefore disrupts an important cell function. The change in the chemical composition of genes Change in hereditary traits. Mutations Beneficial & transmitted to the offspring, Harmful: causes cancer or therefore they’re a source of genetic deformation of newly born or variation. An example ofplant’s. a new trait that appeared in a (These sterility of some Light mutations fur evolved toare help rare.) beach species: Grey mice have a gene that enables them to make a protein called melanin which is the pigment that gives the fur its color. A mutation occurred which disrupted the formation of melanin. The result was appearance of a new trait : light 9 mice survive on white sand dunes, while darker fur help mainland mice survive in fields. fur. Ms. Marim Science 4th primary 2nd term unite1 lesson 2 1- Spontaneous mutations are caused by Exposure to radiation : X ray , atomic radiation. Exposure to chemicals. Exposure to high or very low temperature. Spontaneous mutations variation in traits if they ’re inherited may lead to a varied species 2- Induced mutations are caused by human to get genetic variation in plant & produce desirable traits such as : bigger fruit with better tastes & without seeds. 10 Ms. Marim