Ninth nuclear cardiology invitational conference, Annapolis
... severity of coronary atherosclerosis, none of them identify patients with active disease and who are at risk of plaque rupture. Consequently, approaches to image the vascular wall are desperately needed to improve understanding of the pathobiology of atherosclerosis, to better risk stratify patients ...
... severity of coronary atherosclerosis, none of them identify patients with active disease and who are at risk of plaque rupture. Consequently, approaches to image the vascular wall are desperately needed to improve understanding of the pathobiology of atherosclerosis, to better risk stratify patients ...
Automated External Defibrillation: Whose life will you need to save?
... In 1999, the Heart and Stroke Foundation of Canada organized a conference, Access to Defibrillation - A Vision for 2000 - Strategies for Canada, to bring together the stakeholders in the drive to increase access to defibrillation. Attendees at the conference included physicians, nurses, paramedics, ...
... In 1999, the Heart and Stroke Foundation of Canada organized a conference, Access to Defibrillation - A Vision for 2000 - Strategies for Canada, to bring together the stakeholders in the drive to increase access to defibrillation. Attendees at the conference included physicians, nurses, paramedics, ...
Role of autonomic reflexes in syncope associated with
... between 8 :00 AM and 1 :00 PM . All cardioactive and vasoactive drugs were withdrawn . Informed consent was obtained from all participants . The method of execution of carotid sinus massage and the head-up tilt test have been previously described and validated (7-9) . Carotid sinus massage was perfo ...
... between 8 :00 AM and 1 :00 PM . All cardioactive and vasoactive drugs were withdrawn . Informed consent was obtained from all participants . The method of execution of carotid sinus massage and the head-up tilt test have been previously described and validated (7-9) . Carotid sinus massage was perfo ...
Basic Science Reports
... in swine produces reductions in both coronary blood flow and left ventricular function. In addition, several studies have shown that the complement system is an important mediator in acute myocardial ischemia. However, it is not clear whether the complement activation that occurs causes myocardial i ...
... in swine produces reductions in both coronary blood flow and left ventricular function. In addition, several studies have shown that the complement system is an important mediator in acute myocardial ischemia. However, it is not clear whether the complement activation that occurs causes myocardial i ...
Teaching Rounds in Cardiac Electrophysiology
... EP study, appeared glistening white, compatible with complete fibrotic replacement (P. Tchou, MD, personal communication, July 2011). Histology may reveal myocardial fibrillar disarray, degeneration, and interstitial fibrosis. In 2 patients with congenital sinus node disease who died suddenly, atrop ...
... EP study, appeared glistening white, compatible with complete fibrotic replacement (P. Tchou, MD, personal communication, July 2011). Histology may reveal myocardial fibrillar disarray, degeneration, and interstitial fibrosis. In 2 patients with congenital sinus node disease who died suddenly, atrop ...
Study of the cholinergic system in the heart and its potential
... organ. Moreover, cardiovascular diseases are one of the most often causes of death in human in middle age. Thus, new information about heart, its function, mechanism of regulation or innervations is desired. Heart is innervated by sympathetic and parasympathetic nerves. So far, the most attention wa ...
... organ. Moreover, cardiovascular diseases are one of the most often causes of death in human in middle age. Thus, new information about heart, its function, mechanism of regulation or innervations is desired. Heart is innervated by sympathetic and parasympathetic nerves. So far, the most attention wa ...
Atrial Tachycardia - Thomas Jefferson University
... • Triggered activity – depolarizations that are triggered by the preceding beat and occur during or after ...
... • Triggered activity – depolarizations that are triggered by the preceding beat and occur during or after ...
Treatment-Specific Approaches for Analysis and Control of
... A Left Ventricular Assist Device (LVAD) is a mechanical pump that helps patients with heart failure conditions. This rotary pump works in parallel to the ailing heart and provides an alternative path for blood flow from the weak left ventricle to the aorta. The LVAD is controlled by the power suppli ...
... A Left Ventricular Assist Device (LVAD) is a mechanical pump that helps patients with heart failure conditions. This rotary pump works in parallel to the ailing heart and provides an alternative path for blood flow from the weak left ventricle to the aorta. The LVAD is controlled by the power suppli ...
ACC/AHA Guideline
... Copies: This document is available on the World Wide Web sites of the American College of Cardiology (www.acc.org) and the American Heart Association (my.americanheart.org). A copy of the document is also available at http://www.americanheart.org/presenter.jhtml?identifier⫽3003999 by selecting eithe ...
... Copies: This document is available on the World Wide Web sites of the American College of Cardiology (www.acc.org) and the American Heart Association (my.americanheart.org). A copy of the document is also available at http://www.americanheart.org/presenter.jhtml?identifier⫽3003999 by selecting eithe ...
Tetralogy of Fallot: from fetus to adult
... A fetal echocardiography is important both for the diagnosis of TOF and for the precise characterization of fetus cardiac anatomy, since the TOF associated anatomical variations have different outcomes. As the four-chamber view usually appears normal, TOF is easily missed in a routine ultrasound. [1 ...
... A fetal echocardiography is important both for the diagnosis of TOF and for the precise characterization of fetus cardiac anatomy, since the TOF associated anatomical variations have different outcomes. As the four-chamber view usually appears normal, TOF is easily missed in a routine ultrasound. [1 ...
Cardiac sympathetic afferent stimulation impairs - AJP
... left cardiac sympathetic afferent nerves, we observed sympathoexcitation and the subsequent elevation in MAP. This was essentially similar to previous studies using rats and dogs (29, 32). It is notable that the elevated MAP occurs subsequent to the increase in RSNA without an increase in HR, sugges ...
... left cardiac sympathetic afferent nerves, we observed sympathoexcitation and the subsequent elevation in MAP. This was essentially similar to previous studies using rats and dogs (29, 32). It is notable that the elevated MAP occurs subsequent to the increase in RSNA without an increase in HR, sugges ...
Cardiac Imaging for Coronary Artery Disease
... • Ischemic territories can be identified by using IV gadolinium for a first-pass perfusion study • Dobutamine infusion visualize segments that become ischemic (ie, demonstrate reduced motion) during stress • Direct assessment of coronary plaques ...
... • Ischemic territories can be identified by using IV gadolinium for a first-pass perfusion study • Dobutamine infusion visualize segments that become ischemic (ie, demonstrate reduced motion) during stress • Direct assessment of coronary plaques ...
Slow and Long-Lasting Modulation of
... sequence, we studied the effect of ectopic pacing on the distribution of action potential durations (APDs) in nine isolated Langendorif-perfused rabbit hearts. A contact electrode probe was used to map right and left ventricular-epicardial monophasic action potentials during three consecutive change ...
... sequence, we studied the effect of ectopic pacing on the distribution of action potential durations (APDs) in nine isolated Langendorif-perfused rabbit hearts. A contact electrode probe was used to map right and left ventricular-epicardial monophasic action potentials during three consecutive change ...
Cryoablation Lesion with Atrial Arrhythmia after Fontan Operation
... • Patients with systemic ventricular dysfunction, bilateral superior venae cavae, and heterotaxy syndrome and those undergoing completion Fontan may exhibit a high incidence of these arrhythmias. • The viable extracardiac Fontan may be the operation of choice in a selected subset of patients. • Seri ...
... • Patients with systemic ventricular dysfunction, bilateral superior venae cavae, and heterotaxy syndrome and those undergoing completion Fontan may exhibit a high incidence of these arrhythmias. • The viable extracardiac Fontan may be the operation of choice in a selected subset of patients. • Seri ...
Simvastatin Modulates Remodeling of Kv4.3 Expression in Rat
... Furthermore, it is believed that suppression of repolarizing potassium currents leading to action potential prolongation provides an explanation for QT prolongation/dispersion, thereby accounting for a major mechanism of arrhythmogenesis [1]. Potassium channels include diverse classes of ion channel ...
... Furthermore, it is believed that suppression of repolarizing potassium currents leading to action potential prolongation provides an explanation for QT prolongation/dispersion, thereby accounting for a major mechanism of arrhythmogenesis [1]. Potassium channels include diverse classes of ion channel ...
Bradycardia in Children During General Anaesthesia
... outcome was reported in 63% of both adults and children, in only 48% of incidents concerning children a good outcome was reported. This might indicate that an incident during general anaesthesia with bradycardia in children has an important risk of poor outcome. An epidemiologic study by Keenan and ...
... outcome was reported in 63% of both adults and children, in only 48% of incidents concerning children a good outcome was reported. This might indicate that an incident during general anaesthesia with bradycardia in children has an important risk of poor outcome. An epidemiologic study by Keenan and ...
Deciphering the Sinus Tachycardias
... POTS, and there is a considerable overlap between these for the two entities. Enhanced automaticity of the sinus node13 and abnormal autonomic regulation with excess sympathetic and reduced parasympathetic tone14 are two principal mechanisms proposed for IST. It is unclear whether these mechanisms a ...
... POTS, and there is a considerable overlap between these for the two entities. Enhanced automaticity of the sinus node13 and abnormal autonomic regulation with excess sympathetic and reduced parasympathetic tone14 are two principal mechanisms proposed for IST. It is unclear whether these mechanisms a ...
The Systolic Murmur—Benign or Serious?
... There are three parameters regarding location that are helpful in establishing the possible cause(s) of a systolic murmur: A. Location on precordium of loudest murmur B. Location(s) of radiation or distribution C. Location within systole ...
... There are three parameters regarding location that are helpful in establishing the possible cause(s) of a systolic murmur: A. Location on precordium of loudest murmur B. Location(s) of radiation or distribution C. Location within systole ...
Caffeine and Ventricular Arrhythmias
... patients (77%), more severe in two (9%), and less severe in three (14%). In those patients with clinical ventricular arrhythmias, caffeine did not significantly alter inducibility or severity of arrhythmias, suggesting little effect on the substrate supporting ventricular arrhythmias. ...
... patients (77%), more severe in two (9%), and less severe in three (14%). In those patients with clinical ventricular arrhythmias, caffeine did not significantly alter inducibility or severity of arrhythmias, suggesting little effect on the substrate supporting ventricular arrhythmias. ...
M P I.
... pulmonary embolism. Significant vascular injury has been estimated to occur in approximately 2% of ablation procedures. Cardiac tamponade. Perforation of the myocardium can lead to bleeding into the pericardial space and cardiac tamponade. This complication is estimated to occur in approximately 1% ...
... pulmonary embolism. Significant vascular injury has been estimated to occur in approximately 2% of ablation procedures. Cardiac tamponade. Perforation of the myocardium can lead to bleeding into the pericardial space and cardiac tamponade. This complication is estimated to occur in approximately 1% ...
The Influence of Cardiac Trabeculae on Ventricular
... From a microstructural point of view the trabeculae are roughly homologous with the ventricular wall. The myocardium is composed for about the 70% of its volume by parallel cardiac muscle cells, or myocytes, having a diameter which varies between 10 and 20 μm and a length that ranges between 80 and ...
... From a microstructural point of view the trabeculae are roughly homologous with the ventricular wall. The myocardium is composed for about the 70% of its volume by parallel cardiac muscle cells, or myocytes, having a diameter which varies between 10 and 20 μm and a length that ranges between 80 and ...
PACES/HRS Expert Consensus Statement on the Recognition and
... innovations for CHD of the 1960s and 1970s, coupled with advances in clinical care, have culminated in an increasing and aging cohort with CHD.10 Survival beyond the first year of life has risen from an estimated 25% 50 years ago to 490% expected survival into adulthood.11,12 In a population-based co ...
... innovations for CHD of the 1960s and 1970s, coupled with advances in clinical care, have culminated in an increasing and aging cohort with CHD.10 Survival beyond the first year of life has risen from an estimated 25% 50 years ago to 490% expected survival into adulthood.11,12 In a population-based co ...
Repaired tetralogy of Fallot: the roles of cardiovascular magnetic
... syndrome but without ventricular septal defect–offers a unique opportunity to examine the long-term effects of severe chronic PR without the confounding effects of cyanosis, ventricular septal defect, pulmonary stenosis, or the sequelae of cardiac surgery. In a review of 72 such cases reported in th ...
... syndrome but without ventricular septal defect–offers a unique opportunity to examine the long-term effects of severe chronic PR without the confounding effects of cyanosis, ventricular septal defect, pulmonary stenosis, or the sequelae of cardiac surgery. In a review of 72 such cases reported in th ...
PACES/HRS Expert Consensus Statement on the Recognition and
... innovations for CHD of the 1960s and 1970s, coupled with advances in clinical care, have culminated in an increasing and aging cohort with CHD.10 Survival beyond the first year of life has risen from an estimated 25% 50 years ago to 490% expected survival into adulthood.11,12 In a population-based co ...
... innovations for CHD of the 1960s and 1970s, coupled with advances in clinical care, have culminated in an increasing and aging cohort with CHD.10 Survival beyond the first year of life has risen from an estimated 25% 50 years ago to 490% expected survival into adulthood.11,12 In a population-based co ...
Myocardial infarction
Myocardial infarction (MI) or acute myocardial infarction (AMI), commonly known as a heart attack, occurs when blood flow stops to a part of the heart causing damage to the heart muscle. The most common symptom is chest pain or discomfort which may travel into the shoulder, arm, back, neck, or jaw. Often it is in the center or left side of the chest and lasts for more than a few minutes. The discomfort may occasionally feel like heartburn. Other symptoms may include shortness of breath, nausea, feeling faint, a cold sweat, or feeling tired. About 30% of people have atypical symptoms, with women more likely than men to present atypically. Among those over 75 years old, about 5% have had an MI with little or no history of symptoms. An MI may cause heart failure, an irregular heartbeat, or cardiac arrest.Most MIs occur due to coronary artery disease. Risk factors include high blood pressure, smoking, diabetes, lack of exercise, obesity, high blood cholesterol, poor diet, and excessive alcohol intake, among others. The mechanism of an MI often involves the rupture of an atherosclerotic plaque, leading to complete blockage of a coronary artery. MIs are less commonly caused by coronary artery spasms, which may be due to cocaine, significant emotional stress, and extreme cold, among others. A number of tests are useful to help with diagnosis, including electrocardiograms (ECGs), blood tests, and coronary angiography. An ECG may confirm an ST elevation MI if ST elevation is present. Commonly used blood tests include troponin and less often creatine kinase MB.Aspirin is an appropriate immediate treatment for a suspected MI. Nitroglycerin or opioids may be used to help with chest pain; however, they do not improve overall outcomes. Supplemental oxygen should be used in those with low oxygen levels or shortness of breath. In ST elevation MIs treatments which attempt to restore blood flow to the heart are typically recommended and include angioplasty, where the arteries are pushed open, or thrombolysis, where the blockage is removed using medications. People who have a non-ST elevation myocardial infarction (NSTEMI) are often managed with the blood thinner heparin, with the additional use angioplasty in those at high risk. In people with blockages of multiple coronary arteries and diabetes, bypass surgery (CABG) may be recommended rather than angioplasty. After an MI, lifestyle modifications, along with long term treatment with aspirin, beta blockers, and statins, are typically recommended.Worldwide, more than 3 million people have ST elevation MIs and 4 million have NSTEMIs each year. STEMIs occur about twice as often in men as women. About one million people have an MI each year in the United States. In the developed world the risk of death in those who have had an STEMI is about 10%. Rates of MI for a given age have decreased globally between 1990 and 2010.