Cardiomyocyte proliferation in cardiac development and regeneration
... constriction of the cleavage furrow. Subsequently, we introduced Anillin as an additional marker to evaluate whether a cardiomyocyte will binucleate or divide. Like Ki67, Anillin is absent in G0 phase. In proliferating cells it accumulates in the nucleus during G1, S, and G2 phase, then localizes to ...
... constriction of the cleavage furrow. Subsequently, we introduced Anillin as an additional marker to evaluate whether a cardiomyocyte will binucleate or divide. Like Ki67, Anillin is absent in G0 phase. In proliferating cells it accumulates in the nucleus during G1, S, and G2 phase, then localizes to ...
Role of the autonomic nervous system in the reduced maximal
... Distributions of all variables were evaluated by Levene’s test of equality of variance; parametric tests were used only in case of normal distributions. Differences between the 12 conditions, two levels for acclimatization (SL or WM) times three levels for drug (control, propranolol, or glycopyrrola ...
... Distributions of all variables were evaluated by Levene’s test of equality of variance; parametric tests were used only in case of normal distributions. Differences between the 12 conditions, two levels for acclimatization (SL or WM) times three levels for drug (control, propranolol, or glycopyrrola ...
Percutaneous Left Atrial Appendage Closure Devices for Stroke
... stroke in non-treated patients with atrial fibrillation is 5% per year. Stroke associated with atrial fibrillation is primarily embolic in nature, tends to be more severe than the typical ischemic stroke, and causes higher rates of mortality and disability. As a result, stroke prevention is one of t ...
... stroke in non-treated patients with atrial fibrillation is 5% per year. Stroke associated with atrial fibrillation is primarily embolic in nature, tends to be more severe than the typical ischemic stroke, and causes higher rates of mortality and disability. As a result, stroke prevention is one of t ...
Retrieval of a transcatheter pacemaker in sheep after a mid
... Some may argue that the most common time for retrieval/ extraction would be at end of service. However, for the TPS this may not be the case. With an average implant age of 75 for pacemaker patients and the average longevity of the TPS estimated at 10 years, most patients will not survive past 3 TPS ...
... Some may argue that the most common time for retrieval/ extraction would be at end of service. However, for the TPS this may not be the case. With an average implant age of 75 for pacemaker patients and the average longevity of the TPS estimated at 10 years, most patients will not survive past 3 TPS ...
The Effect of Right Ventricular Filling on the Pressure
... the amount of air above the left ventricular volumetric cylinder. Loops were recorded after a steady state had been achieved (approximately 2-3 minutes). Data were accepted for analysis if the pressure at any time in the initial pressure-volume loop did not differ by more than 5% from pressures obta ...
... the amount of air above the left ventricular volumetric cylinder. Loops were recorded after a steady state had been achieved (approximately 2-3 minutes). Data were accepted for analysis if the pressure at any time in the initial pressure-volume loop did not differ by more than 5% from pressures obta ...
Quantitative Imaging of Diastolic Function using Cardiac Magnetic
... blood velocity and flow, left atrial propagation velocity and atrio-ventricular pressure gradients. Mitral blood velocity and flow were found to have distinct time-courses that become more similar with increasing severity of diastolic dysfunction. Velocity propagation, a wave-like pressure wave phen ...
... blood velocity and flow, left atrial propagation velocity and atrio-ventricular pressure gradients. Mitral blood velocity and flow were found to have distinct time-courses that become more similar with increasing severity of diastolic dysfunction. Velocity propagation, a wave-like pressure wave phen ...
Definitions for a common standard for 2D speckle tracking
... Note that when segmental lengths are different, this fact must be taken into account when computing averages from segmental values. Since the segments are presented with anatomical names corresponding to the LV wall the image refers to, it is necessary that the system recognizes or allows selection ...
... Note that when segmental lengths are different, this fact must be taken into account when computing averages from segmental values. Since the segments are presented with anatomical names corresponding to the LV wall the image refers to, it is necessary that the system recognizes or allows selection ...
Definitions for a common standard for 2D speckle tracking
... Note that when segmental lengths are different, this fact must be taken into account when computing averages from segmental values. Since the segments are presented with anatomical names corresponding to the LV wall the image refers to, it is necessary that the system recognizes or allows selection ...
... Note that when segmental lengths are different, this fact must be taken into account when computing averages from segmental values. Since the segments are presented with anatomical names corresponding to the LV wall the image refers to, it is necessary that the system recognizes or allows selection ...
Verapamil-induced polymorphous ventricular tachycardia
... other preceding conditions was suspected and there was no observed QTc prolongation before the onset of the conversion arrhythmia. The cause of verapamil-induced ventricular arrhythmias is unclear. Interference with the inward calcium current disturbs A V nodal conduction, permitting reentrant rhyth ...
... other preceding conditions was suspected and there was no observed QTc prolongation before the onset of the conversion arrhythmia. The cause of verapamil-induced ventricular arrhythmias is unclear. Interference with the inward calcium current disturbs A V nodal conduction, permitting reentrant rhyth ...
Echocardiographic recognition and implications of
... ABSTRACT The accuracy of two-dimensional echocardiography in the recognition of aberrant ventricular bands and pathologic trabeculations (hypertrophic, fibrotic, or both) was assessed in 35 patients who underwent cardiac transplantation and pathologic examination. At pathologic study the prevalence ...
... ABSTRACT The accuracy of two-dimensional echocardiography in the recognition of aberrant ventricular bands and pathologic trabeculations (hypertrophic, fibrotic, or both) was assessed in 35 patients who underwent cardiac transplantation and pathologic examination. At pathologic study the prevalence ...
For peer review only
... caused by a disturbance in blood supply that did not resolve within 24 hours) confirmed by a standard neurological examination with or without a positive imaging study, or an event of presumed ischemic origin that did not resolve within 24 hours, but the imaging showed a new lesion. 2) Transient isch ...
... caused by a disturbance in blood supply that did not resolve within 24 hours) confirmed by a standard neurological examination with or without a positive imaging study, or an event of presumed ischemic origin that did not resolve within 24 hours, but the imaging showed a new lesion. 2) Transient isch ...
The Autonomic Nervous System and Atrial Fibrillation:The
... junctional reentry (AVNRT) atrial flutter (AFL) and ventricular arrhythmias, clinical electrophysiologists have focused on the myocardial basis of atrial fibrillation (AF). Thus, the strategy for ablation of drug and cardioversion refractory AF was to isolate the myocardial connections from the foca ...
... junctional reentry (AVNRT) atrial flutter (AFL) and ventricular arrhythmias, clinical electrophysiologists have focused on the myocardial basis of atrial fibrillation (AF). Thus, the strategy for ablation of drug and cardioversion refractory AF was to isolate the myocardial connections from the foca ...
Adderall (amphetamine)
... Adults with ADHD may be more prone to procrastination, becoming easily frustrated and taking on many tasks at once while accomplishing none of them. A person may have severe inattention without hyperactivity or impulsivity and still meet criteria for a diagnosis of ADHD. A person with inattentive sy ...
... Adults with ADHD may be more prone to procrastination, becoming easily frustrated and taking on many tasks at once while accomplishing none of them. A person may have severe inattention without hyperactivity or impulsivity and still meet criteria for a diagnosis of ADHD. A person with inattentive sy ...
Guidelines for Cardiac Sonographer Education
... Stress echocardiography. Stress echocardiography is one of the more challenging techniques used in cardiac ultrasonography laboratories. The cardiac sonographer should have extensive experience in the evaluation of patients with ischemic heart disease and a thorough understanding of wall motion abno ...
... Stress echocardiography. Stress echocardiography is one of the more challenging techniques used in cardiac ultrasonography laboratories. The cardiac sonographer should have extensive experience in the evaluation of patients with ischemic heart disease and a thorough understanding of wall motion abno ...
Association of Arginine Vasopressin Levels With Outcomes and the
... Measurement of AVP was part of the primary EVEREST protocol, and subgroup analysis based on baseline AVP was prespecified. Assays for AVP were performed at Covance central laboratories in Geneva and Indianapolis using the Buhlmann radioimmunoassay method.20 Patients were subdivided into high (>8 pg/ ...
... Measurement of AVP was part of the primary EVEREST protocol, and subgroup analysis based on baseline AVP was prespecified. Assays for AVP were performed at Covance central laboratories in Geneva and Indianapolis using the Buhlmann radioimmunoassay method.20 Patients were subdivided into high (>8 pg/ ...
Delayed depolarization of the cog-wheel valve
... mechanism(s) by which shunts are controlled are not well understood (for reviews, see Jones, 1996; Burggren, 1987). Franklin and Axelsson (2000), using an isolated heart model in which the pulmonary outflow tract had been removed, showed that β-adrenergic stimulation reduces resistance in the subpul ...
... mechanism(s) by which shunts are controlled are not well understood (for reviews, see Jones, 1996; Burggren, 1987). Franklin and Axelsson (2000), using an isolated heart model in which the pulmonary outflow tract had been removed, showed that β-adrenergic stimulation reduces resistance in the subpul ...
4D Flow Assessment of Vorticity in Right Ventricular Diastolic
... and ranged from 1.98 mm to 2.60 mm depending on patient size, with a slice thickness of 3 mm for all patients. The field of view was rectangular with voxel volumes ranging from 11.75 to 20.35 mm3 . Other scan parameters were α = 15◦ , TE/TR = 2.85/48.56 ms, venc = 100–150 cm/s and temporal resolutio ...
... and ranged from 1.98 mm to 2.60 mm depending on patient size, with a slice thickness of 3 mm for all patients. The field of view was rectangular with voxel volumes ranging from 11.75 to 20.35 mm3 . Other scan parameters were α = 15◦ , TE/TR = 2.85/48.56 ms, venc = 100–150 cm/s and temporal resolutio ...
Left ventricular performance during prolonged
... during exercise (every 30 min) and after 30 min of recovery. Fluid replacement was provided and monitored during the exercise period. The baseline resting and exercise ejection fractions were 66p2 % and 78p2 % respectively. During exercise, subjects consumed 1816p136 ml of fluid, and the haematocrit ...
... during exercise (every 30 min) and after 30 min of recovery. Fluid replacement was provided and monitored during the exercise period. The baseline resting and exercise ejection fractions were 66p2 % and 78p2 % respectively. During exercise, subjects consumed 1816p136 ml of fluid, and the haematocrit ...
Pericardial Disease - Society of Cardiovascular Anesthesiologists
... and will vary with the respiratory cycle demonstrating pressures of approximately –6 mm Hg at end inspiration and –3 mm Hg at end expiration (NB – as measured by a fluid filled, non-balloon tipped catheter). It is the lowering of intrathoracic and pericardial pressure during inspiration that permits ...
... and will vary with the respiratory cycle demonstrating pressures of approximately –6 mm Hg at end inspiration and –3 mm Hg at end expiration (NB – as measured by a fluid filled, non-balloon tipped catheter). It is the lowering of intrathoracic and pericardial pressure during inspiration that permits ...
Pericardial Diseases: Tamponade and constriction
... superior vena cava) than in the left heart (measured in the pulmonary veins) 9. CXR and cardiac MRI are the two imaging modalities that appear to be most useful in making the definitive diagnosis of congenital absence of the pericardium 9. Pericarditis is an inflammation of the pericardium and can o ...
... superior vena cava) than in the left heart (measured in the pulmonary veins) 9. CXR and cardiac MRI are the two imaging modalities that appear to be most useful in making the definitive diagnosis of congenital absence of the pericardium 9. Pericarditis is an inflammation of the pericardium and can o ...
The role of NT-proBNP in the diagnostics of isolated diastolic
... P , 0.001] and increased with greater severity of the diastolic dysfunction (R ¼ 0.67, P , 0.001). According to the recevier operating characteristic analysis, LV end-diastolic pressure [area under the curve (AUC) 0.84] was the most specific parameter, which had a low sensitivity (61%), however. The ...
... P , 0.001] and increased with greater severity of the diastolic dysfunction (R ¼ 0.67, P , 0.001). According to the recevier operating characteristic analysis, LV end-diastolic pressure [area under the curve (AUC) 0.84] was the most specific parameter, which had a low sensitivity (61%), however. The ...
Colegio Interamericano de Radiología
... or clots within the pericardial cavity. Understanding of the pathophysiological features of cardiac tamponade is essential to diagnosis and treatment. 3 The pericardium is a fibrous sac that contains the heart and that is composed of two layers: the internal or visceral, which is attached to the epic ...
... or clots within the pericardial cavity. Understanding of the pathophysiological features of cardiac tamponade is essential to diagnosis and treatment. 3 The pericardium is a fibrous sac that contains the heart and that is composed of two layers: the internal or visceral, which is attached to the epic ...
Left Ventricular Dysfunction Induced by Monomorphic Ventricular
... yopathy and frequent premature beats, considerable improvement in left ventricular function was observed in 4 of the 5 patients who experienced a notable druginduced decrease in ventricular ectopic activity. This suggests that some patients diagnosed with ventricular arrhythmia secondary to dilated ...
... yopathy and frequent premature beats, considerable improvement in left ventricular function was observed in 4 of the 5 patients who experienced a notable druginduced decrease in ventricular ectopic activity. This suggests that some patients diagnosed with ventricular arrhythmia secondary to dilated ...
Echocardiographic Evaluation of Pericardial Disease
... superior vena cava) than in the left heart (measured in the pulmonary veins)9. CXR and cardiac MRI are the two imaging modalities that appear to be most useful in making the definitive diagnosis of congenital absence of the pericardium9. Pericarditis is an inflammation of the pericardium and can occ ...
... superior vena cava) than in the left heart (measured in the pulmonary veins)9. CXR and cardiac MRI are the two imaging modalities that appear to be most useful in making the definitive diagnosis of congenital absence of the pericardium9. Pericarditis is an inflammation of the pericardium and can occ ...
Myocardial infarction
Myocardial infarction (MI) or acute myocardial infarction (AMI), commonly known as a heart attack, occurs when blood flow stops to a part of the heart causing damage to the heart muscle. The most common symptom is chest pain or discomfort which may travel into the shoulder, arm, back, neck, or jaw. Often it is in the center or left side of the chest and lasts for more than a few minutes. The discomfort may occasionally feel like heartburn. Other symptoms may include shortness of breath, nausea, feeling faint, a cold sweat, or feeling tired. About 30% of people have atypical symptoms, with women more likely than men to present atypically. Among those over 75 years old, about 5% have had an MI with little or no history of symptoms. An MI may cause heart failure, an irregular heartbeat, or cardiac arrest.Most MIs occur due to coronary artery disease. Risk factors include high blood pressure, smoking, diabetes, lack of exercise, obesity, high blood cholesterol, poor diet, and excessive alcohol intake, among others. The mechanism of an MI often involves the rupture of an atherosclerotic plaque, leading to complete blockage of a coronary artery. MIs are less commonly caused by coronary artery spasms, which may be due to cocaine, significant emotional stress, and extreme cold, among others. A number of tests are useful to help with diagnosis, including electrocardiograms (ECGs), blood tests, and coronary angiography. An ECG may confirm an ST elevation MI if ST elevation is present. Commonly used blood tests include troponin and less often creatine kinase MB.Aspirin is an appropriate immediate treatment for a suspected MI. Nitroglycerin or opioids may be used to help with chest pain; however, they do not improve overall outcomes. Supplemental oxygen should be used in those with low oxygen levels or shortness of breath. In ST elevation MIs treatments which attempt to restore blood flow to the heart are typically recommended and include angioplasty, where the arteries are pushed open, or thrombolysis, where the blockage is removed using medications. People who have a non-ST elevation myocardial infarction (NSTEMI) are often managed with the blood thinner heparin, with the additional use angioplasty in those at high risk. In people with blockages of multiple coronary arteries and diabetes, bypass surgery (CABG) may be recommended rather than angioplasty. After an MI, lifestyle modifications, along with long term treatment with aspirin, beta blockers, and statins, are typically recommended.Worldwide, more than 3 million people have ST elevation MIs and 4 million have NSTEMIs each year. STEMIs occur about twice as often in men as women. About one million people have an MI each year in the United States. In the developed world the risk of death in those who have had an STEMI is about 10%. Rates of MI for a given age have decreased globally between 1990 and 2010.